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Street scene of horses at hitching posts. Building on North side was once the Chard Shoe Store, torn down in 1901. North Meridian Street Belle Plaine. Building on South Side was Miss Mersens candy and millenery.

Interior of Ehrenberg Drug Store. Cigar case, stove. P.C. Ehrenberg on left. Belle Plaine.

Shoe Store (interior).

Financial advisers recommend a diverse portfolio to respond to market fluctuations across sectors. Similarly, nature has evolved a diverse portfolio of species to maintain ecosystem function amid environmental fluctuations. In urban planning, public health, transport and communications, food production, and other domains, however, this feature often seems ignored. As we enter an era of unprecedented turbulence at the planetary level, we argue that ample responses to this new reality — that is, response diversity — can no longer be taken for granted and must be actively designed and managed. We describe here what response diversity is, how it is expressed and how it can be enhanced and lost.

Problems of poor network interoperability in electric vehicle (EV) infrastructure, where data about real-time usage or consumption is not easily shared across service providers, has plagued the widespread analysis of energy used for transportation. In this article, we present a high-resolution dataset of real-time EV charging transactions resolved to the nearest second over a one-year period at a multi-site corporate campus. This includes 105 charging stations across 25 different facilities operated by a single firm in the U.S. Department of Energy Workplace Charging Challenge. The high-resolution data has 3,395 real-time transactions and 85 users with both paid and free sessions. The data has been expanded for re-use such as identifying charging behaviour and segmenting user groups by frequency of usage, stage of adoption, and employee type. Potential applications include but are not limited to simulating and parameterizing energy demand models; investigating flexible charge scheduling and optimal power flow problems; characterizing transportation emissions and electric mobility patterns at high temporal resolution; and evaluating characteristics of early adopters and lead user innovation., Measurement(s) Unit of Electric Charge Technology Type(s) Internet Mobile Technology Factor Type(s) charging station location Sample Characteristic - Environment office Sample Characteristic - Location contiguous United States of America Machine-accessible metadata file describing the reported data: 10.6084/m9.figshare.14357123

Digital health is a rapidly developing field which is positioned to transform the manner in which healthcare is delivered, especially amongst adolescents and young adults. In order to assess the efficacy of novel medical devices, clinicians and researchers often turn to the literature for guidance. Randomized control trials and the systematic reviews and meta-analyses that they inform are considered to be at the top of the evidence hierarchy. While they are excellent tools to identify and to summarize the best available evidence to answer a specific research question, they are poorly equipped to provide a more expansive understanding of the body of relevant literature in a timely manner. In this letter we discuss the utility of the scoping review, an underutilized style of academic writing designed to map key concepts in a body of literature. This method is ideal when reporting on the fast-paced field of digital medicine, as it allows for rapid synthesis of the available literature.

Purpose Microbial keratitis (MK) is the most common non-surgical ophthalmic emergency admission in the UK. However, few prospective health-economic studies of MK have been performed, and no specific healthcare resources group (HRG) code exists. This study is designed to determine the feasibility of a data collection tool derived from the microbiology ophthalmology group (MOG) clinical record form, to enable quantification of direct costs of inpatient care, as well as prospective capture of epidemiological data relating to outcomes of MK. Methods Clinical, demographic and economic data were collected retrospectively between January and December 2013 for 101 consecutive patients admitted with MK, using an adaption of the MOG toolset. The direct cost of admission (COA) was calculated using national reference costs and compared to actual income to generate profit/deficit profiles for individual patients. Indices of multiple deprivation were used to assess effect of deprivation on the COA. Results The total income generated through discharge coding was £252,116, compared to a COA of £357,075, yielding a deficit of £104,960 (median: £754 per patient). The cost deficit increased significantly with length of stay (LOS, p Conclusion LOS is the key driver for COA of care for MK admissions. Protocols should encourage discharge of patients who are able to self-administer treatment after the sterilisation phase. The MOG-derived data collection toolset captures pertinent clinical data for quantification of COA. Further development into a multiuser and multisite platform is required for robust prospective testing, together with expansion to capture indirect costs of disease burden, including impact of treatment, visual morbidity and quality of life.

When recovering from the pandemic, it is important for Planet Earth to address the Global Agenda 2030, including food and water crises, and to bounce forward sustainably. The World Economic Forum’s Global Risk Report and Global Agenda 2030 provide a framework for action and an integrated global science agenda response, involving food and health, is essential. The UN 2021 Summit on Food Systems provides an opportunity for the global science community to come together to address the Summit’s Action Tracks, including building resilience to vulnerabilities, shocks and stresses. There would be major global benefits to have an international scientific network working with the UN to address the mandates of the UN Food Summit and Global Agenda 2030.

The Nordic Model is the 20th-century Scandinavian recipe for combining stable democracies, individual freedom, economic growth and comprehensive systems for social security. But what happens when Sweden and Finland – two countries topping global indexes for competitiveness, productivity, growth, quality of life, prosperity, and equality – start doubting themselves and their future? Is the Nordic Model at a crossroads? Historically, consensus, continuity, social cohesion, and broad social trust have been hailed as key components for the success and for the self-images of Sweden and Finland. In the contemporary, however, political debates in both countries are increasingly focused on risks, threats, and worry. Social disintegration, political polarization, geopolitical anxieties, and threat of terrorism are often dominant themes. This book focuses on what appears to be a paradox: countries with low income differences, high faith in social institutions, and relatively high cultural homogeneity becoming fixated on the fear of polarization, disintegration, and diminished social trust. Unpacking the presentist discourse of "worry" and a sense of interregnum at the face of geopolitical tensions, digitalization, and globalization, as well as challenges to democracy, the chapters take steps back in time and explore the current conjecture through the eyes of historians and social scientists, addressing key aspects of and challenges to both the contemporary and future Nordic Model. In addition, the functioning and efficacy of the participatory democracy and current protocols of decision-making are debated. This work is essential reading for students and scholars of the welfare state, social reforms, and populism, as well as Nordic and Scandinavian studies. peerReviewed

Yashadhana A, Zhang JH, Yasmin S, Morjaria P, Holland P, Faal H, et al. Action needed to improve equity and diversity in global eye health leadership. Eye. 2020;34:1051–4. Article Google Scholar Plant GT, Mtanda AT, Arden GB, Johnson GJ. An epidemic of optic neuropathy in Tanzania: characterization of the visual disorder and associated peripheral neuropathy. J Neurol Sci. 1997;145:127–40. CAS Article Google Scholar Chaglasian M, Fingeret M, Gunvant Davey P, Huang W, Leung D, Ng E, et al. The development of a reference database with the Topcon 3D OCT-1 Maestro. Clin Ophthalmol. 2018;12:849–57. Article Google Scholar Girkin CA, Sample PA, Liebmann JM, Jain S, Bowd C, Becerra LM, et al. African Descent and Glaucoma Evaluation Study (ADAGES). Arch Ophthalmol. 2010;128:541–50. Article Google Scholar Poon LY-C, Antar H, Tsikata E, Guo R, Papadogeorgou G, Freeman M, et al. Effects of age, race, and ethnicity on the optic nerve and peripapillary region using spectral-domain OCT 3D volume scans. Transl Vis Sci Technol. 2018;7:12. Article Google Scholar Download references This research was funded by Fight for Sight (grant reference: 24RCO5). Department of Global Health, School of Medicine, University of St Andrews, St Andrews, UK Frederick R. Burgess & Andrew Blaikie Department of Ophthalmology, Princess Alexandra Eye Pavilion, Edinburgh, UK Frederick R. Burgess Dr Agarwal’s Eye Hospital, Dar es Salaam, Tanzania Kazim Dhalla Muhimbili University of Health & Allied Sciences, Dar es Salaam, Tanzania Celina F. Mhina You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar Correspondence to Frederick R. Burgess. We are an international team investigating Tanzanian Endemic Optic Neuropathy (TEON) in Dar es Salaam, Tanzania. FRB, AB, CFM and KD have no competing interests to declare. Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Reprints and Permissions Burgess, F.R., Dhalla, K., Mhina, C.F. et al. Normative data for peripapillary retinal nerve fibre layer OCT scans in patients of African descent. Eye (2020). https://doi.org/10.1038/s41433-020-01180-8 Download citation Received: 23 July 2020 Revised: 01 September 2020 Accepted: 03 September 2020 Published: 11 September 2020 DOI: https://doi.org/10.1038/s41433-020-01180-8

A global effort is ongoing in the scientific community and in the Maker Movement, which focuses on creating devices and tinkering with them, to reverse engineer commercial medical equipment and get it to healthcare workers. For these low-tech solutions to have a real impact, it is important for them to coalesce around approved designs., 8 pages, 1 figure

Since the late 1990s, the trend of plastic waste shipment from developed to developing countries has been increasing. In 2017, China announced an unprecedented ban on its import of most plastic waste, resulting in a sharp decline in global plastic waste trade flow and changes in the treatment structure of countries, whose impacts on global environmental sustainability are enormous but yet unexamined. Here, through the life cycle assessment (LCA) method, we quantified the environmental impacts of changes in the flow patterns and treatment methods of 6 types of plastic waste in 18 countries subsequent to the ban. In the short term, the ban significantly improved four midpoint indicators of environmental impact, albeit contributed to global warming. An annual saving of about 2.35 billion euros of eco-cost was realized, which is equivalent to 56% of plastic waste global trade value in 2017. To achieve global environmental sustainability in the long run, countries should gradually realize the transition from export to domestic management, and from landfill to recycling, which would realize eco-costs savings of about 1.54–3.20 billion euros., China announced a ban on its import of most plastic waste in 2017, resulting in an impact on global environmental sustainability. Here the authors quantify the environmental impacts of changes in the flow patterns and treatment methods of 6 types of plastic waste in 18 countries subsequent to the ban.

We present the Tesco Grocery 1.0 dataset: a record of 420 M food items purchased by 1.6 M fidelity card owners who shopped at the 411 Tesco stores in Greater London over the course of the entire year of 2015, aggregated at the level of census areas to preserve anonymity. For each area, we report the number of transactions and nutritional properties of the typical food item bought including the average caloric intake and the composition of nutrients. The set of global trade international numbers (barcodes) for each food type is also included. To establish data validity we: i) compare food purchase volumes to population from census to assess representativeness, and ii) match nutrient and energy intake to official statistics of food-related illnesses to appraise the extent to which the dataset is ecologically valid. Given its unprecedented scale and geographic granularity, the data can be used to link food purchases to a number of geographically-salient indicators, which enables studies on health outcomes, cultural aspects, and economic factors., Measurement(s)food product type • Purchase • nutrient • energy intake • geographic locationTechnology Type(s)digital curationFactor Type(s)age • sex • population densitySample Characteristic - Environmentgrocery storeSample Characteristic - LocationGreater London Region Machine-accessible metadata file describing the reported data: 10.6084/m9.figshare.11799765

Consumers in most developed countries have greater access to safer food than ever before, yet the issue of consumer perception on the safety of the food supply, the control infrastructure and existing and new process technologies is often not positive. A series of high profile food incidents, which have been ineffectively managed by both the regulators and the industry, and where there has been a failure to be open and transparent, have sensitised a proportion of consumers to scary stories about the food supply. There has been concomitant damage to consumer confidence in (i) the safety of food, (ii) the food industry’s commitment to producing safe food and (iii) the authorities’ ability to oversee the food chain. Threats to consumers’ health and their genuine concerns have to be addressed with effective risk management and the protection of public health has to be paramount. Dealing with incorrect fears and misperceptions of risk has also to be addressed but achieving this is very difficult. The competencies of social scientists are needed to assist in gaining insights into consumer perceptions of risk, consumer behaviour and the determinants of trust. Conventional risk communication will not succeed on its own and more innovative and creative communication strategies are needed to engage with consumers using all available media channels in an open and transparent way. The digital media affords the opportunity to revolutionise engagement with consumers on food safety and nutrition-related issues.

The rapid growth of mobile phones, automated speech recognizing personal assistants, and internet access among the elderly provides new opportunities for incorporating such technologies into clinical research and personalized medical care. Alzheimer’s disease is a good test case given the need for early detection, the high rate of clinical trial failures, the need to more efficiently recruit patients for trials, and the need for sensitive and ecologically valid trial outcomes.

Complexities in food supply chains were highlighted by the so called ‘horsegate’ crisis in 2013, where beef meat was fraudulently adulterated with horse meat causing widespread recalls and subsequent investigations across both retail and food service markets in the European Union (EU). The beef supply chain is a complex supply chain, with global (EU and Non EU) sourcing strategies in order to secure supply. However, managing these complex supply chains can be difficult and consequentially can expose vulnerabilities similar to that of horsemeat, where horsemeat was found in beef meat within EU supply chains. Six months after the crisis broke, an independent review into the integrity and assurance of food supply networks was commissioned by the UK government and undertaken by Professor Chris Elliott of Queen’s University, Belfast. The review recommended eight pillars of food integrity to industry and government: consumers first, zero tolerance, intelligence gathering, laboratory services, audit, government support, leadership and crisis management. This article examines the extent to which these recommendations have been implemented using personal communications from Professor Chris Elliott and relevant industry bodies. Following the review, industry attitudes have changed substantially, testing and surveillance systems have been integrated into normal industry practice and the government is more prepared for future incidents through the establishment of the National Food Crime Unit (NFCU). Horsegate raised the profile of food fraud and crime in supply chains and despite improvements to date, further collaboration between industry and government is required in order to align fully with the recommendations., Food safety: Food fraud prevention is improved after the ‘horsegate’ scandal Industry and government have learned their lessons after the incident in 2013 where beef meat was substituted with horsemeat. Using personal communications with representatives of relevant industry bodies, Moira Dean from the Queen’s University Belfast in UK and her colleagues examined measures the UK government and food industry have taken in response to the horsemeat scandal. They found significant improvement in the understanding and prevention of food fraud, with well-integrated testing and surveillance systems, along with a new government body to take a leadership role in such crises. Yet, collaboration between industry and government is yet to be enhanced. Given the complexities of international food supply chains, the UK lessons and recommendations to improve the integrity of food supply systems, set out in a review commissioned after the horsemeat crisis are relevant to other countries.

Faced with an economic crisis as large and rapid as that precipitated by the COVID-19 pandemic, economists have turned to new 'fast indicators' based on big data, as Andy Haldane and Shiv Chowla of the Bank of England explain.

Traditional sources of retail price information, such as scanner data and government price surveys, are not available for cannabis. To help fill this gap, between October 2016 and July 2018 the UC Agricultural Issues Center collected online retail price ranges for dried cannabis flower and cannabis-oil cartridges at retailers around California. During this 21-month time period, the legal landscape of the California cannabis market underwent three broad regulatory changes: adult-use decriminalization, licensing and regulation and mandatory testing. This article provides unique primary data on legal cannabis prices in California before and after each of these three changes. Our data are imperfect but do provide a glimpse of the patterns of California cannabis prices at different times. For dried cannabis flower, we observe relatively stable retail prices over the 21-month period at both the top and bottom ends of the price range. For cannabis-oil cartridges, we observe relatively stable prices at the bottom end but increasing prices at the top end between November 2017 and July 2018.

In 2018, we surveyed cannabis growers about their experiences with California's commercial cultivation legalization system. Our results suggest high rates of noncompliance with the new regulations. Of the respondents, 31% reported income from cannabis and had not applied for cultivation licenses, indicating a violation of state regulations. These findings highlight the need to further explore conditions that might incentivize growers to apply for cultivation licenses. Respondents' answers and comments indicate modifications to cannabis cultivation licensing programs might be needed to reduce compliance costs and regulatory inconsistencies and to overcome threats of legal repercussions from enhanced bureaucratic oversight. Growers characterized legalization as a process that excludes small growers, contributes to an increase in black market sales and undermines the economies in rural communities. More research is necessary, including on the socioeconomic and environmental contributions that unlicensed small cannabis growers make to rural regions.

We need to feed an estimated population in excess of 9 billion by 2050 with diminishing natural resources, whilst ensuring the health of people and the planet. Herein we connect the future global food demand to the role of agricultural and food science in producing and stabilising foods to meet the global food demand. We highlight the challenges to food and agriculture systems in the face of climate change and global megatrends that are shaping the future world. We discuss the opportunities to reduce food loss and waste, and recover produce that is currently wasted to make this the new raw ingredient supply for the food industry. Our systems-based perspective links food security to agricultural productivity, food safety, health and nutrition, processing and supply chain efficiency in the face of global and industry megatrends. We call for a collaborative, transdisciplinary approach to the science of food security, with a focus on enabling technologies within a context of social, market and global trends to achieve food and nutritional security.

This chapter is co-authored by Dr. Andrew Power, head of the largest art school in Ireland, the Institute of Art, Design, and Technology (IADT) and Dr. Michael MacDonnell, the former dean of Quinn Business School, the leading undergraduate business school in Ireland at University College Dublin (UCD). yes

The first crops obtained through new plant breeding techniques are close to commercialization. Regulatory issues will determine the adoption of the techniques by breeders. Supplementary information The online version of this article (doi:10.1038/nbt.2142) contains supplementary material, which is available to authorized users.

Community Supported Agriculture operations (CSAs) have grown rapidly in recent years. The original model, in which members support a farming operation by paying for produce in advance and receive a share of the farm's produce in return, has been adapted, with much innovation. Since little research existed on CSAs in the Central Valley, we surveyed and carried out in-depth interviews with 54 CSA farmers and two CSA organizers in the Central Valley and surrounding foothills. Here we focus on four aspects of these CSA operations: type, economic viability, farmer characteristics and farm attributes. We found two main CSA models, box and membership/share. Fifty-four percent of the CSAs reported being profitable, and the average gross sales per acre were $9,084. CSA farmers are diverse in political orientation, yet are generally younger, better educated and more likely to be women than the general farming population. CSA farms are relatively small, with a median size of 20 acres; have a median membership of 60 (585 average); use agroecological methods; cultivate agrobiodiversity; and utilize growing practices that generally meet or exceed National Organic Program standards.