117 results on '"Frank Kandziora"'
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2. Becoming an affiliated society of Brain and spine
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Frank Kandziora and Wilco Peul
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
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3. The 2023 Best Paper Awards of our society's Brain & Spine Journal
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Wilco Peul and Frank Kandziora
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
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4. Brain and spine has an impact factor
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Frank Kandziora and Wilco Peul
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
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5. Importance of health policy and systems research for strengthening rehabilitation in health systems: a call to action to accelerate progress
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Walter R. Frontera, Wouter De Groote, Abdul Ghaffar, the Health Policy & Systems Research for Rehabilitation Group, Iben Axen, Muhammad Ehab Azim, Linamara Battistella, Kristian Borg, Ines Campos, Rodrigo Castro, Joaquim Chaler, Leighton Chan, Ignacio Devesa, Deniz Evcik, Giorgio Ferriero, Gerard E. Francisco, Simon French, Steven A. Gard, Douglas P. Gross, Matthieu Guemann, Louise Gustafsson, Allen Heinemann, Claire D. Johnson, Frank Kandziora, Carlotte Kiekens, Jae-Young Lim, Thorsten Meyer, Peggy Nelson, Randolph J. Nudo, Tamara Ownsworth, Wilco Peul, Farooq Azam Rathore, Stefano Respizzi, Christine Rolland, Carla Sabariego, Furqan Ahmed Siddiqi, Manoj Sivan, Birkan Sonel Tur, Henk J. Stam, and Aimee Stewart
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rehabilitation ,health policy ,health services ,evidence-based practice ,research ,world health organisation (WHO) ,Other systems of medicine ,RZ201-999 ,Medical technology ,R855-855.5 - Published
- 2023
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6. Conservative or surgical treatment of pyogenic spinal infection. A retrospective multicenter binational retrospective cohort study.
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Jonathan Neuhoff, Andreas Kramer, Ann-Kathrin Jörger, Olga Berkulian, Santhosh Thavarajasingam, Benjamin Davies, Bernhard Meyer, Frank Kandziora, Ehab Shiban, Andreas Demetriades, and Florian Ringel
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2023
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7. The 'Reviewer of the Year' award 2022/2023
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Frank Kandziora and Wilco Peul
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2023
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8. Why you should publish in a special topic issue of the Brain and Spine Journal
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Frank Kandziora and Wilco Peul
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2023
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9. SPINE20 recommendations 2023: One Earth, one family, one future WITHOUT spine DISABILITY
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Harvinder S. Chhabra, Koji Tamai, Hana Alsebayel, Sami AlEissa, Yahya Alqahtani, Markus Arand, Saumyajit Basu, Thomas R. Blattert, André Bussières, Marco Campello, Giuseppe Costanzo, Pierre Côté, Bambang Darwano, Jörg Franke, Bhavuk Garg, Rumaisah Hasan, Manabu Ito, Komal Kamra, Frank Kandziora, Nishad Kassim, So Kato, Donna Lahey, Ketna Mehta, Cristiano M. Menezes, Eric J. Muehlbauer, Rajani Mullerpatan, Paulo Pereira, Lisa Roberts, Carlo Ruosi, William Sullivan, Ajoy P. Shetty, Carlos Tucci, Sanjay Wadhwa, Ahmed Alturkistany, Jamiu O. Busari, Jeffrey C. Wang, Marco G.A. Teli, Shanmuganathan Rajasekaran, Raghava D. Mulukutla, Michael Piccirillo, Patrick C. Hsieh, Edward J. Dohring, Sudhir K. Srivastava, Jeremie Larouche, Adriaan Vlok, and Margareta Nordin
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Spine care ,Equity ,Digital ,Poverty ,Standardization ,Patient safety ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Introduction: The purpose is to report on the fourth set of recommendations developed by SPINE20 to advocate for evidence-based spine care globally under the theme of “One Earth, One Family, One Future WITHOUT Spine DISABILITY”. Research question: Not applicable. Material and methods: Recommendations were developed and refined through two modified Delphi processes with international, multi-professional panels. Results: Seven recommendations were delivered to the G20 countries calling them to: - establish, prioritize and implement accessible National Spine Care Programs to improve spine care and health outcomes. - eliminate structural barriers to accessing timely rehabilitation for spinal disorders to reduce poverty. - implement cost-effective, evidence-based practice for digital transformation in spine care, to deliver self-management and prevention, evaluate practice and measure outcomes. - monitor and reduce safety lapses in primary care including missed diagnoses of serious spine pathologies and risk factors for spinal disability and chronicity. - develop, implement and evaluate standardization processes for spine care delivery systems tailored to individual and population health needs. - ensure accessible and affordable quality care to persons with spine disorders, injuries and related disabilities throughout the lifespan. - promote and facilitate healthy lifestyle choices (including physical activity, nutrition, smoking cessation) to improve spine wellness and health. Discussion and conclusion: SPINE20 proposes that focusing on the recommendations would facilitate equitable access to health systems, affordable spine care delivered by a competent healthcare workforce, and education of persons with spine disorders, which will contribute to reducing spine disability, associated poverty, and increase productivity of the G20 nations.
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- 2023
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10. 25 years of EUROSPINE
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Frank Kandziora, Marco Teli, Jürgen Meier, and Julie-Lyn Noel
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2023
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11. Rupture of the Superior Sagittal Sinus in Penetrating Head Injury—Management of a Rare Trauma Mechanism
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Holger Schlag, Jonathan Neuhoff, Jens Castein, Christoph Hoffmann, and Frank Kandziora
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penetrating head injury ,superior sagittal sinus ,penetrating brain injury ,fractures ,Surgery ,RD1-811 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Civilian penetrating head injury caused by foreign objects is rare in Germany (Europe), but can result in complex neurovascular damage. We report on a patient who in suicidal intent inflicted on himself a penetrating brain injury near the vertex with a captive bolt gun. A laceration at the junction of the middle to the posterior third of the superior sinus occurred by bolt and bone fragments leading to critical stenosis and subsequent thrombosis. Upon surgery, the proximal and distal sinus openings were completely thrombosed. The sinus laceration was closed by suture and the intraparenchymal bone fragments were retrieved. Postoperative angiography disclosed persistent occlusion of the superior sagittal sinus. The patient did not develop any symptoms due to venous congestion (edema, hemorrhage), suggesting sufficient collateral venous outflow. The patient completely recovered despite the complexity of the lesion.
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- 2022
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12. Future prospects after our successful launch of Brain & Spine
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Wilco Peul and Frank Kandziora
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2022
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13. EUROSPINE and EANS statement about Putin's Ukraine war
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Thomas Blattert, Andreas K. Demetriades, Frank Kandziora, and Wilco Peul
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2022
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14. Reviewing is fun. The Reviewer of the Year Award of the Brain and Spine Journal
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Frank Kandziora and Wilco Peul
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2022
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15. Brain and Spine: Our journal is now indexed in PubMed Central
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Frank Kandziora, Thomas Blattert, Andreas K. Demetriades, and Wilco Peul
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2022
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16. The influence of surgeon experience and subspeciality on the reliability of the AO spine sacral classification system
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Brian Karamian, Gregory Schroeder, Jose Canseco, Lorin Benneker, Frank Kandziora, Shanmuganathan Rajasekaran, Cumhur Öner, Klaus Schnake, Christopher Kepler, and Alexander Vaccaro
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Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2021
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17. Arachnoid cyst with bony erosion of the posterior frontal sinus wall as cause of a subdural empyema after pansinusitis
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Holger Schlag, Christoph Hoffmann, Jens Castein, Jonathan Neuhoff, and Frank Kandziora
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Arachnoid cyst ,Bone erosion ,Pansinusitis ,Subdural empyema ,Surgery ,RD1-811 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Intracranial arachnoid cysts (AC) can lead to a bony thinning of the surrounding skull. We present a young man, in whom a frontal AC has caused a thinning of the frontal calvaria and of the posterior wall of the frontal sinus. This bony vulnerability allowed a frontal sinusitis to spread intracranially and finally led to a subdural empyema with neurological deterioration. The treatment consisted of an emergency craniotomy with evacuation of the empyema and appropriate antibiotic treatment of the causing pathogen (Streptococcus intermedius).
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- 2020
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18. Análise biomecânica de variáveis relacionadas à resistência ao arrancamento dos parafusos do sistema de fixação vertebral Biomechanical analysis of the variables related to the pullout strength of screws in the vertebral fixation system
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Rodrigo César Rosa, Patrícia Silva, Antonio Carlos Shimano, José Batista Volpon, Helton L.A. Defino, Philip Schleicher, and Frank Kandziora
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Coluna vertebral ,Parafusos ósseos ,Biomecânica ,Procedimentos ortopédicos ,Bovinos ,Spine ,Bone screws ,Biomechanics ,Orthopedic procedures ,Cattle ,Medicine ,Orthopedic surgery ,RD701-811 - Abstract
OBJETIVO: Observar a influência do diâmetro do orifício-piloto nos diferentes modos de preparo: sonda de ponta romba, sonda de ponta cortante e broca, com o propósito de avaliar o nível de resistência ao arrancamento de parafusos com diâmetro diverso. MÉTODOS: Parafusos de 5, 6 e 7mm foram inseridos nos corpos de prova de osso bovino. O orifício-piloto foi confeccionado por meio de sonda de ponta romba, sonda de ponta cortante e broca. O diâmetro da perfuração foi menor, igual e maior do que o diâmetro interno do parafuso. Após a inserção dos implantes, nos três diferentes diâmetros para cada modo de preparo do orifício-piloto, foram realizados os ensaios mecânicos de arrancamento. Os ensaios mecânicos realizados em máquina universal de ensaio Emic®, software Tesc 3.13, célula de carga de 2.000N, velocidade de aplicação de força de 2mm/min, pré-carga de 5N e tempo de acomodação de 10 segundos. A propriedade avaliada nos ensaios mecânicos foi a força máxima de arrancamento. RESULTADOS: No grupo de parafusos de 5 e 6mm foi observado aumento na resistência ao arrancamento quando o diâmetro do orifício-piloto era menor que o diâmetro interno do parafuso em todos os modos de preparo (sonda de ponta romba, sonda de ponta cortante e broca). Não foi observada diferença estatística no grupo de parafusos de 7mm para todos os diâmetros de perfuração e modo de preparo do orifício-piloto. CONCLUSÃO: O diâmetro do orifício-piloto influencia a resistência ao arrancamento dos parafusos de sistema de fixação vertebral. A realização de orifício-piloto de diâmetro maior que o diâmetro interno do parafuso reduz a resistência ao arrancamento do implante, independente do modo de preparo do orifício-piloto.OBJECTIVE: To observe the relevance of the pilot hole in the different manners of preparation: dull-tipped probe, cutting-tip probe, and burr, for the purpose of evaluating the level of pullout strength of screws with different diameters. METHODS: Screws of 5, 6, and 7 mm were inserted in the bovine bone test samples. The pilot hole was made with the dull-tipped probe, the cutting-tip probe, and burr. The perforation diameter was smaller, equal, and larger than the inner diameter of the screw. Mechanical pullout assays were performed in the three diameters for each manner of preparation of the pilot hole after inserting the implant. The mechanical assays were performed in an Emic®, Software Tesc 3.13 universal machine with load cell of 2000 N, load application speed of 2 mm/min, pre-load of 5 N, and accommodation time of 10 seconds. The property evaluated in the mechanical assays was the maximum pullout strength. RESULTS: In the group with 5 mm and 6 mm screws, and increase was observed in the pullout strength when the pilot hole diameter was smaller than the inner diameter of the screw in all manners of preparation (dull-tipped probe, cutting-tip probe, and burr). No statistical difference was seen in the seven millimeter screw group for all perforation diameters and manners of preparing the pilot hole. CONCLUSION: The pilot hole diameter has an influence upon the pullout strength of the screws in the vertebral fixation system. The making of a pilot hole with diameter larger than the inner diameter of the screw reduces the pullout strength of the implant, irrespective of the manner of preparation of the pilot hole.
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- 2008
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19. Estudo da influência do diâmetro do orifício piloto na resistência ao arrancamento do parafuso pedicular The influence of pilot hole diameter on screw oullout resistance
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José Roberto Benites Vendrame, Antônio Carlos Shimano, Frank Kandziora, and Helton Luiz Aparecido Defino
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Coluna vertebral ,Parafusos ósseos ,Biomecânica ,Spine ,Bone screws ,Biomechanics ,Medicine ,Orthopedic surgery ,RD701-811 - Abstract
A influência do diâmetro do orifício piloto em relação ao diâmetro interno do parafuso na resistência ao arrancamento do parafuso pedicular foi o objetivo do estudo. Foram utilizados parafusos de 5, 6 e 7 mm do sistema USS de fixação vertebral, os quais foram inseridos nos corpos de prova de madeira, poliuretana e osso. O orifício piloto para a inserção do parafuso foi realizado com brocas de diâmetro inferior, igual e superior ao diâmetro interno do parafuso. Ensaios mecânicos de arrancamento foram realizados em máquina universal de teste. Nos corpos de prova de madeira, poliuretana e osso a realização do orifício piloto com brocas de diâmetro maior que o diâmetro interno do parafuso produziu diminuição da força máxima de arrancamento dos implantes nos ensaios de arrancamento, tendo sido observada diferença estatística. O diâmetro da perfuração do orifício piloto em relação ao diâmetro interno do parafuso exerce influência na resistência ao arrancamento do implante, tendo sido observado aumento da resistência ao arrancamento com a utilização de brocas de diâmetro menor que o diâmetro interno e redução da resistência ao arrancamento com a utilização de brocas com diâmetro maior que o diâmetro interno do parafuso.The influence of the diameter of the pilot hole compared to the inner diameter of the screw on the pull-out resistance of a pedicular screw was studied. 5-, 6-, and 7-mm USS system screws for vertebral fixation were inserted into wood, polyurethane and bone test bodies. The pilot hole for screw insertion was drilled with burrs of smaller, equal or wider diameter than the inner diameter of the screw. Mechanical pull-out assays were performed using a universal testing machine. In the wood, polyurethane and bone test bodies, a pilot hole drilled with burrs of a wider diameter than the inner diameter of the screw produced reduced maximum pull-out strength on the implants, with statistical significance. The drilling diameter of the pilot hole compared to the inner diameter of the screw influences implant pull-out strength, with an increased pull-out resistance being observed with the use of smaller diameter burrs as compared to the inner diameter, and a reduction of pull-out resistance being observed with the use of burrs of a wider diameter than the inner diameter of the screw.
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- 2008
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20. Estudo da influência do modo de preparação do orifício piloto e do macheamento na ancoragem dos parafusos pediculares Study of the influence of the type of pilot hole preparation and tapping on pedicular screws fixation
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Helton Luiz Aparecido Defino, José Roberto Benites Vendrame, Antônio Carlos Shimano, and Frank Kandziora
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Fixação de fratura ,Parafusos ósseos ,Coluna vertebral ,Fracture fixation ,Bone screws ,Spine ,Medicine ,Orthopedic surgery ,RD701-811 - Abstract
Foram realizados ensaios mecânicos com parafusos do sistema de fixação vertebral USIS para o estudo da influência do tipo de preparo do orifício piloto com sonda ou brocas e o macheamento do trajeto do orifício piloto, na resistência ao arrancamento dos implantes. Os parafusos foram inseridos em corpos de prova de madeira, poliuretana e osso bovino. O preparo do orifício piloto foi realizado com sondas e brocas de 3,5mm. Foram formados três grupos experimentais: I-perfuração com sonda, II-perfuração com broca e III-perfuração com broca e macheamento. Após a sua inserção nos corpos de prova foram realizados ensaios de arrancamento em máquina universal de teste. Foi observado aumento da resistência ao arrancamento dos implantes com a realização do orifício piloto com sondas e a diferença estatística foi significativa em relação ao preparo com broca e broca associada ao macheamento. Não foi observada diferença na resistência ao arrancamento dos parafusos com o macheamento do trajeto do orifício piloto.Mechanical assays were performed with screws of the USIS vertebral fixation system for the study of the influence of type of pilot hole preparation with probe or burr and tapping of the pilot hole pathway on pedicular screw pullout. The screws were inserted into wood, polyurethane and bovine bone test bodies. The pilot hole was prepared with probes and burrs of 3.5 mm. Three experimental groups were formed: I -drilling with a probe, II - drilling with a burr, and III - drilling with burr and tapping. After screw insertion into the test bodies, pullout assays were performed with a universal test machine. Increased screw pullout resistance was observed when the pilot hole was drilled with a probe, with a statistically significant difference compared to preparation with a burr and with a burr in combination with tapping. No difference in screw pullout resistance was observed with tapping of the pilot hole pathway.
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- 2007
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21. Influência do diâmetro do orifício piloto na resistência ao arrancamento dos parafusos do corpo vertebral The influence of pilot hole diameter on screw pullout resistance
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Helton L. A. Defino, Célia Regina Galloro Wichr, Antônio Carlos Shimano, and Frank Kandziora
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Coluna vertebral ,Parafusos osso ,Biomecânica ,Spine ,Bone screw ,Biomechanics ,Medicine ,Orthopedic surgery ,RD701-811 - Abstract
Foram realizados ensaios mecânicos com o objetivo de avaliar a influência do diâmetro do orifício piloto em relação ao diâmetro interno do parafuso na resistência ao arrancamento dos parafusos do sistema de fixação vertebral aplicados no corpo da vértebra. O estudo foi realizado em duas etapas. Na primeira etapa foram utilizados corpos de prova de poliuretana para a colocação de parafusos de 5mm e, 6mm , e na segunda etapa os parafusos foram inseridos na face lateral dos corpos das vértebras lombares de suínos. O orifício piloto foi realizado com brocas de diâmetro menor, igual ou maior que o diâmetro interno do parafuso. Foram realizados ensaios mecânicos de arrancamento em máquina universal de teste para a avaliação da força máxima de arrancamento dos implantes. Foi observado que o diâmetro do orifício piloto em relação ao diâmetro interno do parafuso influencia na resistência ao arrancamento dos implantes.Mechanical assays were performed in order to assess the influence of pilot hole diameter versus screw's inner diameter on screw pullout resistance in the vertebral fixation systems applied to the vertebral body. The study was conducted in two stages. In the first, polyurethane test bodies were used for placing 5 and 6 mm screws, and, in the second stage, the screws were inserted into the lateral surface of the lumbar vertebral bodies of pigs. The pilot hole was built with drills with smaller, similar or larger diameter than screws' inner diameter. Mechanical pullout assays were performed using a universal test machine for the assessment of maximum pullout screw resistance. The diameter of the pilot hole versus screw's inner diameter was shown to influence screw pullout resistance.
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- 2007
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22. Hybrid Stabilization of Thoracic Spine Fractures with Sublaminar Bands and Transpedicular Screws: Description of a Surgical Alternative and Review of the Literature
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Marie-Therese Unterweger, Frank Kandziora, and Klaus J. Schnake
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Orthopedic surgery ,RD701-811 - Abstract
Stabilization of unstable thoracic fractures with transpedicular screws is widely accepted. However, placement of transpedicular screws can cause complications, particularly in the thoracic spine with physiologically small pedicles. Hybrid stabilization, a combination of sublaminar bands and pedicle screws, might reduce the rate of misplaced screws and can be helpful in special anatomic circumstances, such as preexisting scoliosis and osteoporosis. We report about two patients suffering from unstable thoracic fractures, of T5 in one case and T3, T4, and T5 in the other case, with preexisting scoliosis and extremely small pedicles. Additionally, one patient had osteoporosis. Patients received hybrid stabilization with pedicle screws adjacent to the fractured vertebral bodies and sublaminar bands at the level above and below the pedicle screws. No complications occurred. Follow-up was 12 months with clinically uneventful postoperative courses. No signs of implant failure or loss of reduction could be detected. In patients with very small thoracic pedicles, scoliosis, and/or osteoporosis, hybrid stabilization with sublaminar bands and pedicle screws can be a viable alternative to long pedicle screw constructs.
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- 2015
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23. Estudo da influência do torque de inserção na resistência ao arrancamento dos parafusos pediculares The influence of insertion torque on pedicular screws' pullout resistance
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Vânia Custódio Leite, Antônio Carlos Shimano, Gilson Antonio Pereira Gonçalves, Frank Kandziora, and Helton Luiz Aparecido Defino
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Coluna vertebral ,Parafusos ósseos ,Biomecânica ,Dispositivos de fixação ortopédica ,Spine ,Bone screws ,Biomechanics ,Orthopedic fixation devices ,Medicine ,Orthopedic surgery ,RD701-811 - Abstract
Foram realizados ensaios mecânicos para avaliação do torque de inserção na resistência ao arrancamento dos parafusos pediculares. Foram utilizadas no estudo 30 vértebras de suínos da raça Landrace, nas quais parafusos de 5mm foram inseridos nos pedículos vertebrais. O orifício piloto foi realizado com brocas de 2,5mm, 3,8mm e 4,5mm. Foram realizados ensaios mecânicos de arrancamento dos implantes em máquina universal de testes. Foi observado aumento do torque de inserção dos parafusos com a perfuração do orifício piloto com diâmetro menor que o diâmetro interno do parafuso, e redução com o orifício piloto maior que o diâmetro interno do parafuso. Foi observada diferença estatística entre os valores do torque de inserção. A resistência ao arrancamento dos implantes aumentou com a perfuração do orifício piloto com valores menores que o diâmetro interno do parafuso e diminuiu com a perfuração com diâmetro maior que o diâmetro interno do parafuso. Foi observada diferença estatística dos valores da resistência ao arrancamento dos implantes apenas com a perfuração do orifício piloto com diâmetro maior que o diâmetro interno do parafuso.Mechanical assays were performed in order to evaluate the effect of the insertion torque on the pullout resistance of pedicular screws. Thirty vertebrae of Landrace pigs were used in the study, with 5-mm screws being inserted into the vertebral pedicles. The pilot hole was drilled with 1.5, 3.8 and 4.5 mm burrs. Mechanical assays of implant pullout resistance were performed with a universal testing machine. An increase in the insertion torque of the screws was observed when a pilot hole with a smaller diameter than the inner diameter of the screw was drilled, and a reduction was observed when the diameter of the pilot hole was larger than the inner diameter of the screw. A statistically significant difference in the insertion torque values was observed. The pullout resistance of the implants increased when the pilot hole had a smaller diameter than the inner diameter of the screw and decreased when the pilot hole had a larger diameter than the inner diameter of the screw. A statistically significant difference in implant pullout resistance was observed only when the diameter of the pilot hole was larger than the inner diameter of the screw.
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- 2008
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24. Health professionals’ perspective on the applicability of AO Spine PROST (patient reported outcome Spine trauma) in people with a motor-complete traumatic or non-traumatic spinal cord injury
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Aline J. Hakbijl - van der Wind, Marcel W. M. Post, Tijn van Diemen, Klaus J. Schnake, Lorin M. Benneker, Frank Kandziora, Shanmuganathan Rajasekaran, Gregory D. Schroeder, Alexander R. Vaccaro, F. Cumhur Öner, and Said Sadiqi
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Outcome measure ,Health ,Orthopedics and Sports Medicine ,Surgery ,Spine trauma ,Spinal cord injury ,Function ,AO spine PROST - Abstract
Purpose The AO Spine PROST (Patient Reported Outcome Spine Trauma) was developed for people with spine trauma and minor or no neurological impairment. The purpose is to investigate health professionals’ perspective on the applicability of the AO Spine PROST for people with motor-complete traumatic or non-traumatic spinal cord injury (SCI), using a discussion meeting and international survey study. Methods A discussion meeting with SCI rehabilitation physicians in the Netherlands was performed, followed by a worldwide online survey among the AO Spine International community, involved in the care of people with SCI. Participants rated the comprehensibility, relevance, acceptability, feasibility and completeness of the AO Spine PROST on a 1–5 point scale (5 most positive). Comments could be provided per question. Results The discussion meeting was attended by 13 SCI rehabilitation physicians. The survey was completed by 196 participants. Comprehensibility (mean ± SD: 4.1 ± 0.8), acceptability (4.0 ± 0.8), relevance (3.9 ± 0.8), completeness (3.9 ± 0.8), and feasibility (4.1 ± 0.7) of the AO Spine PROST were rated positively for use in people with motor-complete traumatic or non-traumatic SCI. Only a few participants questioned the relevance of items on the lower extremities (e.g., walking) or missed items on pulmonary functioning and complications. Some recommendations were made for improvement in instructions, terminology and examples of the tool. Conclusion Health professionals found the AO Spine PROST generally applicable for people with motor-complete traumatic or non-traumatic SCI. This study provides further evidence for the use of the AO Spine PROST in spine trauma care, rehabilitation and research, as well as suggestions for its further development.
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- 2023
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25. SPINE20 recommendations 2022: spine care-working together to recover stronger
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Bambang Darwono, Koji Tamai, Pierre Côté, Sami Aleissa, Agus Hadian Rahim, Paulo Pereira, Hana Alsobayel, Harvinder S. Chhabra, Giuseppe Costanzo, Manabu Ito, Frank Kandziora, Donna Lahey, Cristiano M. Menezes, Sohail Bajammal, William J. Sullivan, Peter Vajkoczy, Alaa Ahmad, Markus Arand, Saiful Asmiragani, Thomas R. Blattert, Jamiu Busari, Edward J. Dohring, Bernardo Misaggi, Eric J. Muehlbauer, Raghava D. Mulukutla, Everard Munting, Michael Piccirillo, Carlo Ruosi, Ahmed Alturkistany, Marco Campello, Patrick C. Hsieh, Marco G. A. Teli, Jeffrey C. Wang, and Margareta Nordin
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Wellness ,Rehabilitation ,Value-based care ,Capacity building ,Orthopedics and Sports Medicine ,Surgery ,HEALTH ,SPINE20 ,POLICY - Abstract
Purpose Globally, spine disorders are the leading cause of disability, affecting more than half a billion individuals. However, less than 50% of G20 countries specifically identify spine health within their public policy priorities. Therefore, it is crucial to raise awareness among policy makers of the disabling effect of spine disorders and their impact on the economic welfare of G20 nations. In 2019, SPINE20 was established as the leading advocacy group to bring global attention to spine disorders. Methods Recommendations were developed through two Delphi methods with international and multi-professional panels. Results In 2022, seven recommendations were delivered to the leaders of G20 countries, urging them to: Develop action plans to provide universal access to evidence-based spine care that incorporates the needs of minorities and vulnerable populations. Invest in the development of sustainable human resource capacity, through multisectoral and inter-professional competency-based education and training to promote evidence-based approaches to spine care, and to build an appropriate healthcare working environment that optimizes the delivery of safe health services. Develop policies using the best available evidence to properly manage spine disorders and to prolong functional healthy life expectancy in the era of an aging population. Create a competent workforce and improve the healthcare infrastructure/facilities including equipment to provide evidence-based inter-professional rehabilitation services to patients with spinal cord injury throughout their continuum of care. Build collaborative and innovative translational research capacity within national, regional, and global healthcare systems for state-of-the-art and cost-effective spine care across the healthcare continuum ensuring equality, diversity, and inclusion of all stakeholders. Develop international consensus statements on patient outcomes and how they can be used to define and develop pathways for value-based care. Recognize that intervening on determinants of health including physical activity, nutrition, physical and psychosocial workplace environment, and smoking-free lifestyle can reduce the burden of spine disabilities and improve the health status and wellness of the population. At the third SPINE20 summit 2022 which took place in Bali, Indonesia, in August 2022, 17 associations endorsed its recommendations. Conclusion SPINE20 advocacy efforts focus on developing public policy recommendations to improve the health, welfare, and wellness of all who suffer from spinal pain and disability. We propose that focusing on facilitating access to systems that prioritize value-based care delivered by a competent healthcare workforce will reduce disability and improve the productivity of the G20 nations.
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- 2022
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26. SPINE20 recommendations 2021
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Giuseppe Costanzo, Bernardo Misaggi, Luca Ricciardi, Sami I. AlEissa, Koji Tamai, Fahad Alhelal, Yahya Alqahtani, Hana I. Alsobayel, Markus Arand, Massimo Balsano, Thomas R. Blattert, Marco Brayda-Bruno, Jamiu O. Busari, Marco Campello, Harvinder S. Chhabra, Francesco Ciro Tamburrelli, Pierre Côté, Bambang Darwono, Frank Kandziora, Giovanni A. La Maida, Eric J. Muehlbauer, Raghava D. Mulukutla, Paulo Pereira, Shanmuganathan Rajasekaran, Dominique A. Rothenfluh, William J. Sullivan, Eeric Truumees, Edward J. Dohring, Tim Pigott, Ajoy P. Shetty, Marco G. A. Teli, Jeffrey C. Wang, Christopher Ames, Johannes R. Anema, Anand Bang, Kenneth M. C. Cheung, Douglas P. Gross, Scott Haldeman, Salvatore Minisola, Rajani Mullerpatan, Stefano Negrini, Louis-Rachid Salmi, M. Silvia Spinelli, Adriaan Vlok, Kwadwo P. Yankey, Fabio Zaina, Ahmed Alturkistany, Jörg Franke, Ulf R. Liljenqvist, Michael Piccirillo, and Margareta Nordin
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Clinical Sciences ,Clinical Neurology ,Biomedical Engineering ,Clinical Research ,Behavioral and Social Science ,Humans ,Orthopedics and Sports Medicine ,Pandemics ,Aged ,Science & Technology ,Advocacy group ,G20 ,Recommendation ,Spine ,SPINE20 ,Rehabilitation ,Pain Research ,COVID-19 ,Settore MED/34 - Medicina Fisica e Riabilitativa ,Quality Education ,recommendation ,spine ,advocacy group ,Good Health and Well Being ,Orthopedics ,Italy ,Surgery ,Spinal Diseases ,Neurosciences & Neurology ,Chronic Pain ,Life Sciences & Biomedicine ,CHRONIC PAIN - Abstract
Purpose The focus of SPINE20 is to develop evidence-based policy recommendations for the G20 countries to work with governments to reduce the burden of spine disease, and disability. Methods On September 17–18, 2021, SPINE20 held its annual meeting in Rome, Italy. Prior to the meeting, the SPINE20 created six proposed recommendations. These recommendations were uploaded to the SPINE20 website 10 days before the meeting and opened to the public for comments. The recommendations were discussed at the meeting allowing the participants to object and provide comments. Results In total, 27 societies endorsed the following recommendations. SPINE20 calls upon the G20 countries: (1) to expand telehealth for the access to spine care, especially in light of the current situation with COVID-19. (2) To adopt value-based interprofessional spine care as an approach to improve patient outcomes and reduce disability. (3) To facilitate access and invest in the development of a competent rehabilitation workforce to reduce the burden of disability related to spine disorders. (4) To adopt a strategy to promote daily physical activity and exercises among the elderly population to maintain an active and independent life with a healthy spine, particularly after COVID-19 pandemic. (5) To engage in capacity building with emerging countries and underserved communities for the benefit of spine patients. (6) To promote strategies to transfer evidence-based advances into patient benefit through effective implementation processes. Conclusions SPINE20’s initiatives will make governments and decision makers aware of efforts to reduce needless suffering from disabling spine pain through education that can be instituted across the globe.
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- 2022
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27. Lumbo-sacral Junction Instability by Traumatic Sacral Fractures: Isler’s Classification Revisited – A Narrative Review
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Rishi M Kanna, Shanmuganathan Rajasekaran, Gregory D Schroeder, Klaus Schnake, Alexander R Vaccaro, Lorin Benneker, Cumhur F Oner, Frank Kandziora, and Emiliano Vialle
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Orthopedics and Sports Medicine ,Surgery ,Neurology (clinical) - Abstract
Study Design Narrative review Objectives Multiple classifications have been proposed for sacral fractures since the last century. While initial classifications focussed on vertical and transverse fractures, the recent fracture classifications encompass all injury patterns. In 1990, Isler classified unilateral vertical sacral fractures based on its potential influence on lumbo-sacral joint (LSJ) stability. Methods We re-visited the original description of Isler’s classification of sacral fractures and subsequent studies that have cited it. We will further describe basic LSJ anatomy, evolution of sacral classification systems and the use of Isler’s classification system as it relates to LSJ instability and chronic low back pain. Results Isler described a subset of unilateral vertical sacral fractures where the fracture line exited medial or through the L5-S1 facet joint, based on radiographic review of 193 sacral fractures (incidence -3.5%). He stated that such a fracture should be recognised as it can impede hemi-pelvis reduction and can result in late LSJ instability. The article has been cited in 106 studies and only a few studies have described the incidence of this variant. Nevertheless, the injury is considered as an indication for surgical fixation. Conclusion A review of various classifications indicates that sacral fractures have three important bio-mechanical implications, namely, pelvic ring continuity (vertical fractures), spino-pelvic alignment (high transverse fractures) and lumbo-sacral joint integrity (Isler’s fractures). Though there is a universal recognition of Isler’s fractures and its impact on LSJ integrity, there is a lack of clinical and bio-mechanical evidence regarding the concept of instability caused by a unilateral Isler fracture.
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- 2022
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28. Die Untersuchung der Lendenwirbelsäule
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Frank Kandziora, Jonathan Neuhoff, and Holger Schlag
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business.industry ,Medicine ,business - Published
- 2021
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29. Leitliniengerechte Therapie von Verletzungen der subaxialen Halswirbelsäule
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Jens Castein, Matti Scholz, Frank Kandziora, and Philipp Schleicher
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Gynecology ,medicine.medical_specialty ,business.industry ,Fracture fixation ,Emergency Medicine ,medicine ,Orthopedics and Sports Medicine ,Surgery ,Hand surgery ,business - Abstract
Verletzungen der subaxialen HWS nehmen zu und weisen ein im Vergleich zu Brust- und Lendenwirbelsaule erhohtes neurologisches Risiko auf. Dargestellt werden die aktuellen Behandlungsempfehlungen gemas den Therapieempfehlungen der Sektion Wirbelsaule (DGOU) und der S1-Leitlinie der DGU. Der vorliegende 2. Teil des Beitrags beschreibt die korrekte Indikationsstellung und Therapieplanung fur Halswirbelverletzungen. Ausgehend von der AOSpine-Klassifikation fur subaxiale HWS-Verletzungen konnen Entscheidungen uber eine konservative oder operative Therapie sowie einzelne Details der Therapie getroffen werden. Die grundlegenden Therapieprinzipien lauten Entlastung neurologischer Strukturen, Wiederherstellung von Stabilitat und Rekonstruktion/Erhalt des physiologischen Alignments.
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- 2021
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30. Reliability, validity and responsiveness of the Dutch version of the AOSpine PROST (Patient Reported Outcome Spine Trauma)
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F. Cumhur Oner, Jens R. Chapman, Alexander R. Vaccaro, Frank Kandziora, Klaus J. Schnake, Lorin Michael Benneker, Said Sadiqi, Allard J. F. Hosman, Marcel F. Dvorak, Marcel W M Post, S. Rajasekaran, and Extremities Pain and Disability (EXPAND)
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medicine.medical_specialty ,Intraclass correlation ,Concurrent validity ,610 Medicine & health ,Spine trauma ,Spearman's rank correlation coefficient ,GUIDE ,Correlation ,Patient perspective ,03 medical and health sciences ,0302 clinical medicine ,Cronbach's alpha ,QUALITY-OF-LIFE ,SF-36 ,medicine ,Content validity ,AOSpine PROST ,Orthopedics and Sports Medicine ,Function ,Reliability (statistics) ,030222 orthopedics ,HEALTH-STATUS ,business.industry ,INSTRUMENTS ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,Health ,Physical therapy ,Surgery ,Patient-reported outcome ,business ,Outcome instrument ,030217 neurology & neurosurgery - Abstract
Purpose To validate the Dutch version of AOSpine PROST (Patient Reported Outcome Spine Trauma). Methods Patients were recruited from two level-1 trauma centers from the Netherlands. Next to the AOSpine PROST, patients also filled out SF-36 for concurrent validity. Descriptive statistics were used to analyze the characteristics. Content validity was assessed by evaluating the number of inapplicable or missing questions. Also floor and ceiling effects were analyzed. Internal consistency was assessed by calculating Cronbach’s α and item-total correlation coefficients (itcc). Spearman correlation tests were performed within AOSpine PROST items and in correlation with SF-36. Test–retest reliability was analyzed using Intraclass Correlation Coefficients (ICC). Responsiveness was assessed by calculating effect sizes (ES) and standardized response mean (SRM). Factor analysis was performed to explore any dimensions within AOSpine PROST. Results Out of 179 enrolled patients, 163 (91.1%) were included. Good results were obtained for content validity. No floor or ceiling effects were seen. Internal consistency was excellent (Cronbach’s α = 0.96, itcc 0.50–0.86), with also good Spearman correlations (0.25–0.79). Compared to SF-36, the strongest correlation was seen for physical functioning (0.79; p p 1), explaining 65.4% of variance. Conclusions Very satisfactory results were obtained for reliability, validity and responsiveness of the Dutch version of AOSpine PROST. Treating surgeons are encouraged to use this novel and validated tool in clinical setting and research to contribute to evidence-based and patient-centered care.
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- 2021
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31. Primäre benigne Knochentumoren der Wirbelsäule
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Christoph Hoffmann, Andreas Pingel, and Frank Kandziora
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business.industry ,Medicine ,business - Published
- 2020
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32. Minimal-invasive Techniken bei traumatischen Halswirbelsäulenverletzungen
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Matti Scholz, Frank Kandziora, Philipp Schleicher, and Andreas Pingel
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Gynecology ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,030208 emergency & critical care medicine ,Hand surgery ,Cervical spine ,03 medical and health sciences ,0302 clinical medicine ,Emergency Medicine ,Medicine ,Orthopedics and Sports Medicine ,Surgery ,business - Abstract
Wahrend minimal-invasive Verfahren fur die Versorgung von Brust- und Lendenwirbelverletzungen inzwischen Standard sind, sind solche Techniken an der Halswirbelsaule (HWS) noch nicht etabliert. Dies hat neben anatomischen und technischen Grunden auch die Ursache darin, dass das altbewahrte ventrale Vorgehen bereits die Kriterien der Minimal-Invasivitat weitgehend erfullt und auf die meisten Verletzungen anwendbar ist. Die vorhandene Literatur besteht im Wesentlichen aus Fallberichten und kleinen Kohortenstudien, deren Ergebnisse vorgestellt werden. Von nahezu samtlichen offenen Verfahren, v. a. an der oberen HWS, aber auch an der subaxialen HWS, ist auch eine minimal-invasive Variante beschrieben. Die Weiterentwicklung dieser vielversprechenden Techniken im Rahmen groser Studien steht noch aus.
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- 2020
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33. Leitliniengerechte Diagnostik bei Verletzungen der subaxialen Halswirbelsäule
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Frank Kandziora, Philipp Schleicher, Matti Scholz, and Jens Castein
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Gynecology ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,030208 emergency & critical care medicine ,Hand surgery ,Guideline ,Cervical spine ,03 medical and health sciences ,0302 clinical medicine ,Emergency Medicine ,medicine ,Orthopedics and Sports Medicine ,Surgery ,business - Abstract
Verletzungen der subaxialen Halswirbelsaule (HWS) nehmen zu und weisen ein im Vergleich zu Brust- und Lendenwirbelsaule hohes neurologisches Risiko auf. Dargestellt werden die aktuellen Behandlungsempfehlungen gemas den Empfehlungen der Sektion Wirbelsaule (Deutsche Gesellschaft fur Orthopadie und Unfallchirurgie, DGOU) sowie der S1-Leitlinie der Deutschen Gesellschaft fur Unfallchirurgie (DGU). Sowohl hoch- als auch niedrigenergetische Unfalle konnen eine HWS-Verletzung zur Folge haben. Besteht der klinische Verdacht auf das Vorliegen einer HWS-Verletzung, ist eine schnittbildgebende Untersuchung (CT/MRT) Methode der Wahl. Die Klassifikation der Verletzung erfolgt anhand der AOSpine-Klassifikation fur subaxiale Verletzungen. Davon ausgehend kann eine Entscheidung uber eine konservative oder eine operative Therapie sowie einzelne Details der Versorgung getroffen werden.
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- 2020
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34. Minimal-invasive transforaminale lumbale interkorporelle Fusion
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Frank Kandziora and Christoph-Heinrich Hoffmann
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Foraminal stenosis ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,Hand surgery ,medicine.disease ,Spondylolisthesis ,Degenerative disc disease ,03 medical and health sciences ,Plastic surgery ,0302 clinical medicine ,Lumbar interbody fusion ,Orthopedic surgery ,medicine ,Orthopedics and Sports Medicine ,Surgery ,Complication rate ,business ,Nuclear medicine ,030217 neurology & neurosurgery - Abstract
Fusion und Stabilisation lumbaler Bewegungssegmente in einer minimal-invasiven Technik. Degenerative Bandscheibenerkrankungen, Segmentdegenerationen, degenerative Spondylolisthesen, isthmische Spondylolisthesen, Pseudarthrosen, andere spinale Instabilitaten, Bandscheibenvorfall, Revisionsoperationen bei Postnukleotomiesyndrom, neuroforaminale Stenosen, Facettenarthrose. Hohergradige Spondylolisthesen (Meyerding Grad III und IV, Spondyloptosen), Notwendigkeit bilateraler Wurzeldekompression, Wirbelkorperfrakturen, Tumoren, hohergradige spinale Instabilitaten, primare spinale Deformitaten, Multi-level-Pathologien. Ipsilateraler minimal-invasiver Zugang zur Lendenwirbelsaule (LWS) mithilfe eines selbsthaltenden tubularen Retraktorsystems, partielle oder vollstandige Facettektomie, Implantation von Pedikelschrauben und des TLIF(„transforaminal lumbar interbody fusion“)-Cages unter Schonung der Nervenwurzeln, Fusion, kontralaterale Pedikelschraubeninsertion in minimal-invasiver oder perkutaner Technik. Postoperative Mobilisation nach physiotherapeutischer Anleitung, Rontgenkontrolle nach Mobilisation (LWS im Stehen, 2 Ebenen), Follow-up-Untersuchung (klinisch und radiologisch) nach 6 bis 12 Wochen sowie 1 Jahr postoperativ. Fusionsrate >90 %, vergleichbar mit der offenen TLIF. Komplikationsraten niedriger als bei offener TLIF. Kurzere Bestrahlungszeiten und -dosen, niedrigerer intraoperativer Blutverlust. Geringes chirurgisches Trauma fuhrt zu kurzerer Hospitalisationszeit und Arbeitsunfahigkeit. Signifikante Reduktion des ODI (Oswestry Disability Index) und VAS(visuelle Analogskala)-Scores.
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- 2020
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35. Two-level ACDF with a zero-profile stand-alone spacer compared to conventional plating: a prospective randomized single-center study
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Frank Kandziora, Philipp Schleicher, Andreas Pingel, B Onal, Christoph-Heinrich Hoffmann, and Matti Scholz
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medicine.medical_specialty ,Single Center ,law.invention ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Randomized controlled trial ,law ,Statistical significance ,medicine ,Clinical endpoint ,Humans ,Orthopedics and Sports Medicine ,Prospective Studies ,030222 orthopedics ,business.industry ,Dysphagia ,Surgery ,Spinal Fusion ,Treatment Outcome ,Radiological weapon ,Cervical Vertebrae ,Secondary Outcome Measure ,Neurosurgery ,medicine.symptom ,business ,Bone Plates ,030217 neurology & neurosurgery ,Diskectomy - Abstract
Stand-alone zero-profile devices have already proven safety, and a reduced dysphagia rate was assumed. So far, no level-one evidence is available to prove the proposed advantages of zero-profile implants in multilevel procedures. The aim of this RCT was to compare the clinical and radiological outcome of a zero-profile spacer versus cage + plate in two-level ACDF. Consecutive patients with contiguous two-level cDD were randomly assigned either to the interventional group (zero-profile device) or to the control group (cage + plate). Primary endpoint of the study was the prevalence of dysphagia at 24 months. Disability, progress of adjacent segment degeneration, fusion status and loss of correction were analyzed as secondary outcome measure. Primary outcome parameter was statistically analyzed by Chi-square test. Forty-one patients met inclusion criteria and were randomly assigned to the interventional and the control group. Dysphagia was frequent in either group at 3 months FU favoring interventional group (p = 0.078). At final FU, less patients of the interventional group complained about dysphagia, but the difference was not significant. No relevant differences at final FU were recorded for NPDI, loss of correction and adjacent-level degeneration. Fusion rate was slightly lower in the interventional group. Two-level ACDF either by a stand-alone zero-profile spacer or cage + plate is safe. Using a zero-profile cage dysphagia was infrequent at 24 months, but the value did not reach statistical significance in comparison with the cage + plate. Hence, this randomized trial was not able to prove the proposed clinical superiority for dysphagia rates for zero-profile anchored spacer in two-level cDD.
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- 2020
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36. Wirbelsäulenverletzungen im Kindesalter – Ergebnisse einer nationalen Multizenterstudie mit 367 Patienten
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Andreas Badke, Matti Scholz, Christian Herren, Frank Kandziora, Christian Knop, Jan-Sven Jarvers, Christian Blume, Alexander C. Disch, Thomas Weiß, Holger Meinig, Holger Siekmann, Christoph Strüwind, Thomas Welk, Peter C. Strohm, Philipp Kobbe, Michael Kreinest, Michael Ruf, Hauke Rüther, Matthias K. Jung, Christoph E. Heyde, Ulrich J. Spiegl, Oliver Gonschorek, and Stefan Matschke
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Gynecology ,medicine.medical_specialty ,Injury control ,business.industry ,Accident prevention ,Poison control ,Pediatric spine ,Conservative treatment ,Multicenter study ,Emergency Medicine ,medicine ,Orthopedics and Sports Medicine ,Surgery ,business - Abstract
Generell stellen Wirbelsaulenverletzungen bei Kindern im Alter unter 16 Jahren eine seltene Verletzungsentitat dar. Fur Deutschland liegen keine belastbaren Daten bezuglich der Epidemiologie von Verletzungen der Wirbelsaule im Kindesalter vor. Gerade bei padiatrischen Patienten, bei denen sowohl die Anamnese, die klinische Untersuchung, aber auch die Durchfuhrung der bildgebenden Diagnostik haufig erschwert sind, mussen samtliche Hinweise auf eine Verletzung der Wirbelsaule mitberucksichtigt werden. Das Ziel der vorliegenden Studie war die Bereitstellung epidemiologischer Daten von padiatrischen Patienten mit Wirbelsaulenverletzungen in Deutschland, um diese zukunftig in die Entscheidungsfindung bei der Diagnostik und Therapie dieser Patienten einfliesen lassen zu konnen. Im Rahmen einer nationalen Multizenterstudie wurden retrospektiv Patientendaten innerhalb eines Zeitraums von 7 Jahren aus 6 Wirbelsaulenzentren erhoben. Neben den demografischen Daten wurden der Unfallmechanismus, die betroffene Wirbelsaulenregion und auch die Begleitverletzungen erhoben. Zudem erfolgte die Erfassung der bildgebenden Diagnostik sowie der jeweiligen Therapie. Es konnten 367 Kinder (weiblich: mannlich = 1:1,2) mit insgesamt 610 Verletzungen an der Wirbelsaule in die Studie eingeschlossen werden. Das mittlere Alter betrug 12 (±3,5) Jahre. Die haufigsten Unfallmechanismen in allen Altersgruppen waren ein Sturz aus unter 3 m Hohe sowie Verkehrsunfalle. Die bildgebende Diagnostik musste nur in Ausnahmefallen in Narkose durchgefuhrt werden. Wahrend jungere Kinder (0 bis 9 Jahre) eher Verletzungen im Bereich der Halswirbelsaule erlitten, zeigten sich Verletzungen der thorakolumbalen Wirbelsaule eher bei Kindern >10 Jahren. Die Kinder wiesen haufige Begleitverletzungen an Kopf und Extremitaten auf. Im Bereich der Wirbelsaule befanden sich weitere Verletzungen meist benachbart und nur selten in anderen Regionen. Rund 75 % der Kinder wurden konservativ behandelt. Die Ergebnisse unterscheiden sich von den Erkenntnissen aus der Erwachsenenmedizin und beschreiben spezielle Gegebenheiten fur padiatrische Patienten mit Wirbelsaulenverletzungen. Trotz gewisser Limitationen konnen sie so bei der Entscheidungsfindung uber die durchzufuhrende Diagnostik und Therapie dieser Patienten helfen.
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- 2020
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37. 187. An international validation of the AO Spine Upper Cervical Injury Classification
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Mark Lambrechts, Gregory D. Schroeder, Brian Karamian, Jose A. Canseco, Christopher K. Kepler, F. Cumhur Oner, Lorin M. Benneker, Shanmuganathan Rajasekaran, Marcel F. Dvorak, Frank Kandziora, Mohammad El-Sharkawi, Richard J. Bransford, Andrei F. Joaquim, Masahiko Takahata, Waeel Hamouda, Klaus J. Schnake, and Alexander R. Vaccaro
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Surgery ,Orthopedics and Sports Medicine ,Neurology (clinical) - Published
- 2022
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38. Development and reliability of the AOSpine CROST (Clinician Reported Outcome Spine Trauma): a tool to evaluate and predict outcomes from clinician’s perspective
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Jeroen J. M. Renkens, Lorin Michael Benneker, Emiliano Neves Vialle, Jens R. Chapman, Said Sadiqi, Sander P. J. Muijs, Frank Kandziora, Alexander R. Vaccaro, Klaus J. Schnake, Marcel W M Post, F. Cumhur Oner, Orthopedics and Sports Medicine, and Extremities Pain and Disability (EXPAND)
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medicine.medical_specialty ,LUMBAR SPINE ,Intraclass correlation ,Kyphosis ,Clinician perspective ,610 Medicine & health ,Spine trauma ,CLASSIFICATION ,PARAMETERS ,Cohen's kappa ,Quality of life ,Cronbach's alpha ,FRACTURES ,QUALITY-OF-LIFE ,medicine ,NEUROLOGICAL-STATUS ,INJURY ,Humans ,Orthopedics and Sports Medicine ,Patient Reported Outcome Measures ,AOSpine CROST ,Reliability (statistics) ,Observer Variation ,Surgeons ,RELEVANT ,Descriptive statistics ,business.industry ,Reproducibility of Results ,Clinical parameters ,medicine.disease ,Outcome (probability) ,KYPHOSIS ,Radiological parameters ,Spinal Injuries ,Physical therapy ,Surgery ,business ,Outcome instrument - Abstract
Purpose To report on the development of AOSpine CROST (Clinician Reported Outcome Spine Trauma) and results of an initial reliability study. Methods The AOSpine CROST was developed using an iterative approach of multiple cycles of development, review, and revision including an expert clinician panel. Subsequently, a reliability study was performed among an expert panel who were provided with 20 spine trauma cases, administered twice with 4-week interval. The results of the developmental process were analyzed using descriptive statistics, the reliability per parameter using Kappa statistics, inter-rater rater agreement using intraclass correlation coefficient (ICC), and internal consistency using Cronbach’s α. Results The AOSpine CROST was developed and consisted of 10 parameters, 2 of which are only applicable for surgically treated patents (‘Wound healing’ and ‘Implants’). A dichotomous scoring system (‘yes’ or ‘no’ response) was incorporated to express expected problems for the short term and long term. In the reliability study, 16 (84.2%) participated in the first round and 14 (73.7%) in the second. Intra-rater reliability was fair to good for both time points (κ = 0.40–0.80 and κ = 0.31–0.67). Results of inter-rater reliability were lower (κ = 0.18–0.60 and κ = 0.16–0.46). Inter-rater agreement for total scores showed moderate results (ICC = 0.52–0.60), and the internal consistency was acceptable (α = 0.76–0.82). Conclusions The AOSpine CROST, an outcome tool for the surgeons, was developed using an iterative process. An initial reliability analysis showed fair to moderate results and acceptable internal consistency. Further clinical validation studies will be performed to further validate the tool.
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- 2020
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39. Screw-Related Complications After Instrumentation of the Osteoporotic Spine: A Systematic Literature Review With Meta-Analysis
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Roger Härtl, M. Spruit, Jack E. Zigler, Jean Ouellet, Frank Kandziora, Elke Rometsch, Christian Mazel, Kathrin Espinoza, and Venugopal K. Menon
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musculoskeletal diseases ,complications ,medicine.medical_treatment ,Osteoporosis ,Dentistry ,medicine ,Orthopedics and Sports Medicine ,ddc:610 ,screw loosening ,Instrumentation (computer programming) ,Pedicle screw ,Review Articles ,pedicle screws ,business.industry ,screw augmentation ,medicine.disease ,musculoskeletal system ,equipment and supplies ,osteoporosis ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,aged ,Systematic review ,surgical procedures, operative ,Screw loosening ,Meta-analysis ,Spinal fusion ,spinal fusion ,adverse effects ,Surgery ,Neurology (clinical) ,business - Abstract
Study Design: Systematic literature review with meta-analysis. Objective: Osteoporosis is common in elderly patients, who frequently suffer from spinal fractures or degenerative diseases and often require surgical treatment with spinal instrumentation. Diminished bone quality impairs primary screw purchase, which may lead to loosening and its sequelae, in the worst case, revision surgery. Information about the incidence of spinal instrumentation-related complications in osteoporotic patients is currently limited to individual reports. We conducted a systematic literature review with the aim of quantifying the incidence of screw loosening in osteoporotic spines. Methods: Publications on spinal instrumentation of osteoporotic patients reporting screw-related complications were identified in 3 databases. Data on screw loosening and other local complications was collected. Pooled risks of experiencing such complications were estimated with random effects models. Risk of bias in the individual studies was assessed with an adapted McHarm Scale. Results: From 1831 initial matches, 32 were eligible and 19 reported screw loosening rates. Studies were heterogeneous concerning procedures performed and risk of bias. Screw loosening incidences were variable with a pooled risk of 22.5% (95% CI 10.8%-36.6%, 95% prediction interval [PI] 0%-81.2%) in reports on nonaugmented screws and 2.2% (95% CI 0.0%-7.2%, 95% PI 0%-25.1%) in reports on augmented screws. Conclusions: The findings of this meta-analysis suggest that screw loosening incidences may be considerably higher in osteoporotic spines than with normal bone mineral density. Screw augmentation may reduce loosening rates; however, this requires confirmation through clinical studies. Standardized reporting of prespecified complications should be enforced by publishers.
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- 2020
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40. Konservative Behandlung von Wirbelfrakturen in BWS und LWS – was geht wie?
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Ulas Yildiz, Philipp Schleicher, Jens Castein, and Frank Kandziora
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Gynecology ,medicine.medical_specialty ,education.field_of_study ,business.industry ,Population ,Intervertebral disc ,medicine.disease ,Surgery ,Conservative treatment ,03 medical and health sciences ,Stenosis ,0302 clinical medicine ,Lumbar ,medicine.anatomical_structure ,Deconditioning ,medicine ,Orthopedics and Sports Medicine ,Spinal canal ,030212 general & internal medicine ,education ,business ,030217 neurology & neurosurgery ,Pain therapy - Abstract
The basis for assessing thoracolumbar vertebral body fractures are two established classification systems. Important, especially in terms of further treatment, is the distinction between osteoporotic and healthy bones. The AO Spine classification offers a comprehensive tool for healthy bones to reliably specify the morphological criterias (alignment, integrity of the intervertebral disc, fragment separation, stenosis of the spinal canal). In addition to the fracture morphology, the OF classification for osteoporotic fractures includes patient-specific characteristics to initiate adequate therapy. In general an adequate pain therapy is required for early rehabilitation. While in the bone healthy population, physiotherapy reduces the risk of muscle deconditioning, in the osteoporotic population it additionally serves to prevent subsequent fractures. Unlike osteoporotic patients, bone healthy patients with vertebral fractures should not undergo a corset/orthosis treatment.
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- 2019
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41. Prof. Herbert Junghanns (1902 – 1986) – eine widersprüchliche Karriere
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Frank Kandziora and Wolfgang Dube
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Orthopedics and Sports Medicine ,Surgery - Published
- 2019
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42. Sagittale Balance und posttraumatische Kyphose – Teil 2
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Frank Kandziora, Matti Scholz, Philipp Schleicher, and Andreas Pingel
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business.industry ,Medicine ,business - Published
- 2019
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43. Treatment of Fractures of the Thoracolumbar Spine: Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)
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Ulrich J. Spiegl, Wolfgang Lehmann, S. Katscher, Philipp Kobbe, Erol Gercek, Philipp Schleicher, Christian W. Müller, Rainer H. Meffert, Stefan Hauck, Christoph Josten, Alexander Hoelzl, Christian Knop, Akhil P. Verheyden, Christian Schinkel, Christoph Ulrich, Frank Kandziora, Helmut Ekkerlein, Matti Scholz, and Axel Partenheimer
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medicine.medical_specialty ,Section (typography) ,Article ,German ,03 medical and health sciences ,0302 clinical medicine ,morphological modifiers ,medicine ,Orthopedics and Sports Medicine ,Orthodontics ,030222 orthopedics ,thoracolumbar spine fracture ,business.industry ,therapy recommendations ,traumatic vertebral body fractures ,Thoracolumbar spine ,operative therapy ,language.human_language ,3. Good health ,Spine (zoology) ,conservative therapy ,Orthopedic surgery ,language ,Surgery ,Neurology (clinical) ,Operative therapy ,business ,030217 neurology & neurosurgery - Abstract
Study Design: Abstract consensus paper with systematic literature review. Objective: The aim of this study was to establish recommendations for treatment of thoracolumbar spine fractures based on systematic review of current literature and consensus of several spine surgery experts. Methods: The project was initiated in September 2008 and published in Germany in 2011. It was redone in 2017 based on systematic literature review, including new AOSpine classification. Members of the expert group were recruited from all over Germany working in hospitals of all levels of care. In total, the consensus process included 9 meetings and 20 hours of video conferences. Results: As regards existing studies with highest level of evidence, a clear recommendation regarding treatment (operative vs conservative) or regarding type of surgery (posterior vs anterior vs combined anterior-posterior) cannot be given. Treatment has to be indicated individually based on clinical presentation, general condition of the patient, and radiological parameters. The following specific parameters have to be regarded and are proposed as morphological modifiers in addition to AOSpine classification: sagittal and coronal alignment of spine, degree of vertebral body destruction, stenosis of spinal canal, and intervertebral disc lesion. Meanwhile, the recommendations are used as standard algorithm in many German spine clinics and trauma centers. Conclusion: Clinical presentation and general condition of the patient are basic requirements for decision making. Additionally, treatment recommendations offer the physician a standardized, reproducible, and in Germany commonly accepted algorithm based on AOSpine classification and 4 morphological modifiers.
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- 2018
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44. Treatment of Atlas Fractures: Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)
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Andreas Korge, Frank Kandziora, Klaus J. Schnake, Andreas Pingel, Philipp Schleicher, P. Kluger, Ulas Yildiz, Matthias Pumberger, and Matti Scholz
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medicine.medical_specialty ,injury ,cervical spine ,C1/2 fusion ,Article ,Posterior stabilization ,German ,surgery ,axial compression ,03 medical and health sciences ,0302 clinical medicine ,C1 ,atlas osteosynthesis ,Atlas (anatomy) ,Axial compression ,medicine ,Orthopedics and Sports Medicine ,atlas ,030222 orthopedics ,Posterior fusion ,business.industry ,General surgery ,language.human_language ,instability ,medicine.anatomical_structure ,fracture ,transverse atlantal ligament (TAL) ,Orthopedic surgery ,language ,Traumatic spondylolisthesis ,Narrative review ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Study Design: Narrative review and expert recommendation. Objectives: To establish treatment recommendations for atlas fractures based on the knowledge of the experts of the Spine Section of the German Society for Orthopaedics and Trauma. Methods: Neither high-level evidence studies comparing conservative and operative management nor studies matching different operative treatment strategies exist. This recommendation summarizes the knowledge of the experts of the Spine Section of the German Society for Orthopaedics and Trauma with regard to the treatment of atlas fractures. Results: Most atlas fractures are the result of compression forces. A valuable morphological classification system has been described by Gehweiler. For an adequate diagnosis, a computed tomography is mandatory. To distinguish between stable and unstable type 3 injuries, it is necessary to evaluate the integrity of the transverse atlantal ligament (TAL) with magnetic resonance imaging and to classify the TAL lesions. The majority of atlas fractures are stable and will be successfully managed conservatively. Unstable atlas fractures (type 3b and sagittal split type 4 fractures) should be treated by surgical stabilization. Unstable atlas fractures (type 3b) with a midsubstance ligamentous disruption or severely dislocated ligamentous bony avulsions of the TAL can successfully be treated by a C1/2 fusion. Unstable atlas fractures (type 3b) with a moderately dislocated ligamentous bony avulsion of the TAL and sagittal split type 4 fractures may be treated by atlas osteosynthesis only. Conclusions: Whereas the majority of atlas fractures can be managed conservatively, in specific fracture patterns surgical treatment strategies have become the standard of care.
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- 2018
45. Treatment of Injuries to the Subaxial Cervical Spine: Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)
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Andreas Badke, Miguel Pishnamaz, Erol Gercek, Gregor Schmeiser, M. Reinhold, Philipp Hartung, Philipp Kobbe, Helmut Ekkerlein, Matti Scholz, Stefan Matschke, Frank Kandziora, Klaus J. Schnake, Volker Zimmermann, Christian W. Müller, Bernhard Ullrich, Thomas Weiss, Florian Hans Brakopp, Gregor Stein, Philipp Schleicher, Jan-Sven Jarvers, Robert Morrison, and René Hartensuer
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medicine.medical_specialty ,injury ,Section (typography) ,Article ,German ,03 medical and health sciences ,0302 clinical medicine ,lower cervical spine ,subaxial cervical spine ,medicine ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,ACDF ,Orthodontics ,business.industry ,Cervical spine ,language.human_language ,Spine (zoology) ,fracture ,consensus ,treatment recommendations ,Orthopedic surgery ,language ,Surgery ,Neurology (clinical) ,business ,German Society for Orthopaedics and Trauma ,030217 neurology & neurosurgery - Abstract
Study Design: Expert consensus. Objectives: To establish treatment recommendations for subaxial cervical spine injuries based on current literature and the knowledge of the Spine Section of the German Society for Orthopaedics and Trauma. Methods: This recommendation summarizes the knowledge of the Spine Section of the German Society for Orthopaedics and Trauma. Results: Therapeutic goals are a stable, painless cervical spine and protection against secondary neurologic damage while retaining maximum possible motion and spinal profile. The AOSpine classification for subaxial cervical injuries is recommended. The Canadian C-Spine Rule is recommended to decide on the need for imaging. Computed tomography is the favoured modality. Conventional x-ray is preserved for cases lacking a “dangerous mechanism of injury.” Magnetic resonance imaging is recommended in case of unexplained neurologic deficit, prior to closed reduction and to exclude disco-ligamentous injuries. Computed tomography angiography is recommended in high-grade facet joint injuries or in the presence of vertebra-basilar symptoms. A0-, A1- and A2-injuries are treated conservatively, but have to be monitored for progressive kyphosis. A3 injuries are operated in the majority of cases. A4- and B- and C-type injuries are treated surgically. Most injuries can be treated with anterior plate stabilization and interbody support; A4 fractures need vertebral body replacement. In certain cases, additive or pure posterior instrumentation is needed. Usually, lateral mass screws suffice. A navigation system is advised for pedicle screws from C3 to C6. Conclusions: These recommendations provide a framework for the treatment of subaxial cervical spine Injuries. They give advice about diagnostic measures and the therapeutic strategy.
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- 2018
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46. Verletzungen der Halswirbelsäule: ventrale Spondylodesetechniken
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Frank Kandziora, Philipp Schleicher, Matti Scholz, and Andreas Pingel
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Gynecology ,030222 orthopedics ,03 medical and health sciences ,medicine.medical_specialty ,0302 clinical medicine ,Cervical fracture ,business.industry ,Cervical approach ,medicine ,business ,medicine.disease ,030217 neurology & neurosurgery - Abstract
ZusammenfassungVentrale Spondylodesetechniken werden regelhaft zur Versorgung von Verletzungen der Halswirbelsäule angewandt. Dieser Beitrag soll Ihnen Indikationen, die technische Umsetzung, Nachbehandlung wie auch die potenziellen Komplikationen ventraler Spondylodesetechniken an der Halswirbelsäule näher bringen.
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- 2018
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47. Sagittale Balance und posttraumatische Kyphose
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Frank Kandziora, Jörg Franke, and Andreas Pingel
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Gynecology ,medicine.medical_specialty ,business.industry ,medicine ,business ,Spine trauma - Abstract
ZusammenfassungDieser Übersichtsartikel soll in die Grundlagen der sagittalen Balance der Wirbelsäule einführen, die diagnostischen Maßnahmen und insbesondere die Messmethoden des Wirbelsäulenprofils und der Beckenparameter darstellen sowie als typisches Krankheitsbild einer sagittalen Deformität die posttraumatische Kyphose vorstellen. In einem zweiten Teil in einem der folgenden Hefte werden die spezifischen konservativen und operativen Behandlungsmethoden von sagittalen Profilstörungen unter besonderer Berücksichtigung der posttraumatischen kyphotischen Wirbelsäulendeformitäten beschrieben.
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- 2018
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48. Thorakolumbale Frakturen
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Matti Scholz and Frank Kandziora
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- 2017
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49. Dorsale atlantoaxiale Stabilisierung in Goel-Harms-Technik
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Matti Scholz, Frank Hildebrand, Frank Kandziora, and Philipp Kobbe
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030222 orthopedics ,medicine.medical_specialty ,Sports medicine ,business.industry ,General surgery ,MEDLINE ,030208 emergency & critical care medicine ,Hand surgery ,03 medical and health sciences ,Plastic surgery ,0302 clinical medicine ,Emergency Medicine ,medicine ,Orthopedics and Sports Medicine ,Surgery ,Internal Fixators ,business - Published
- 2017
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50. Therapieempfehlungen zur Versorgung von Verletzungen der subaxialen Halswirbelsäule
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Thomas Weiß, Christian W. Müller, Stefan Matschke, Gregor Stein, Jan-Sven Jarvers, Florian Hans Brakopp, Philipp Kobbe, Miguel Pishnamaz, Volker Zimmermann, Frank Kandziora, Klaus J. Schnake, M. Reinhold, Helmut Ekkerlein, Robert Morrison, Matti Scholz, Bernhard Ullrich, Andreas Badke, Gregor Schmeiser, Rene Hartensuer, Erol Gercek, Philipp Hartung, and Philipp Schleicher
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Gynecology ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,Cervical spine ,Bone screws ,03 medical and health sciences ,0302 clinical medicine ,X ray computed ,Bone plate ,medicine ,Orthopedics and Sports Medicine ,Surgery ,business ,030217 neurology & neurosurgery - Abstract
ZusammenfassungIm Rahmen eines Konsensusprozesses der Arbeitsgruppe „subaxiale HWS-Verletzungen“ der Sektion Wirbelsäule der DGOU erfolgte in 4 Sitzungen im Jahre 2016 die Erstellung der vorliegenden Therapieempfehlungen unter Berücksichtigung der vorhandenen Literatur. Therapieziele sind eine dauerhaft stabile, schmerzfreie Halswirbelsäule und der Schutz vor sekundären neurologischen Schäden unter größtmöglicher Berücksichtigung der Beweglichkeit und des Wirbelsäulenprofils. Aufgrund der Praktikabilität und der guten Evaluation hinsichtlich Reliabilität sollte die AOSpine-Klassifikation für subaxiale HWS-Verletzungen für die Klassifikation zur Anwendung kommen. Es wird die Canadian C-Spine Rule als klinischer Algorithmus zur Entscheidung hinsichtlich der Notwendigkeit einer bildgebenden Diagnostik empfohlen. Bei gemäß dieser Regel anamnestisch oder klinisch hohem Verdacht auf eine strukturelle, instabile Verletzung ist die Spiral-CT der HWS Verfahren der Wahl. Die konventionelle Röntgendiagnostik in 2 Ebenen bleibt Fällen vorbehalten, in denen kein „gefährlicher Unfallmechanismus“ vorliegt. Die Indikation für die MRT der HWS wird vor allem bei nicht erklärbaren neurologischen Symptomen, bei geplanter geschlossener Reposition und dorsaler Stabilisierung und zum Ausschluss vermuteter diskoligamentärer Verletzungen empfohlen, wobei hier je nach Befundkonstellation eine abgestufte Dringlichkeit gilt. Die CT-Angiografie wird bei höhergradigen Facettengelenkverletzungen oder bei Vorliegen vertebrobasilärer Symptome empfohlen. Die konventionelle Funktionsdiagnostik wird ausschließlich in Form der ärztlich geführten dynamischen Bildwandlerdurchleuchtung bei persistierendem Verdacht auf eine instabile Verletzung empfohlen. Die therapeutische Strategie richtet sich primär nach der Verletzungsmorphologie, die in der AOSpine-Klassifikation beschrieben wird. A0-Frakturen sollten konservativ behandelt werden. A1- und A2-Frakturen sollten meistens konservativ behandelt werden, wobei die segmentale Kyphose in Einzelfällen eine OP-Indikation bedingen kann. A3-Frakturen stellen in den meisten Fällen eine OP-Indikation dar, in Einzelfällen ist eine konservative Behandlung möglich. A4-Frakturen sowie die B- und C-Verletzungen bedürfen einer operativen Therapie. Die ventrale Plattenspondylodese mit interkorporeller Abstützung (bei Berstungskomponente durch Korporektomie und Wirbelkörperersatz) wird für die meisten Verletzungen empfohlen, eine rein dorsale oder zusätzlich dorsale Stabilisierung kann bei besonderer Befundkonstellation möglich oder sogar notwendig sein. In diesen Fällen ist die Instrumentierung mit Massa-lateralis-Schrauben zumeist ausreichend; bei Anwendung von Pedikelschrauben in Höhe C III – C VI wird ein Navigationssystem empfohlen. Bei Vorliegen einer ankylosierenden Grunderkrankung (M3-Modifikator) wird hingegen die dorsale, langstreckige Stabilisierung favorisiert.
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- 2017
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