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SAR-FOR-REG is a prospective observational study. All Sarcoidosis patients seen at Morgagni Hospital, Forlì (Italy), between July 2024 and July 2026, will be recorded in the SAR-FOR-REG database. At every visit, KSQ, mMRC and FAS score will be administered and data will be collected: symptoms, examination, laboratory tests, radiological tests (CT, MRI, CT/PET, US), lung function, cardiovascular tests, drugs, comorbidities, family history. Primary Objective. to create a registry to be used for clinical studies: 1) predictive factors of disease exacerbation, deterioration despite treatment, side effects; 2) outcome of paucisymptomatic patients treated with steroids; 3) role of symptoms in therapeutic decisions; 4) KSQ and FAS validation in Italian speaking population; 5) heart involvement incidence [ABSTRACT FROM AUTHOR]

Viene descritto un caso clinico in cui la malattia renale cronica all'esordio non presentava difficoltà nell'inquadramento diagnostico (pielonefrite cronica associata a calcolosi renale). Gli esami successivi hanno invece mostrato la presenza di una lieve ipercalcemia con soppressione del PTH. Vengono analizzate le possibili cause di ipercalcemia ed in ultimo dei livelli elevati di 1,25 (OH)2 vit. D. Segue una breve rassegna delle forme cliniche della sarcoidosi con un esame delle possibili indagini diagnostiche utili a formulare la diagnosi di sarcoidosi. Infine il decorso clinico con la risposta favorevole alla terapia steroidea rende ragione dei molteplici aspetti patogenetici implicati nel danno renale da sarcoidosi.

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