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152 results on '"Shi, Shuting"'

22. A Domain Generalization Method Based on Hybrid Meta-Learning for Face Anti-Spoofing

Author

Shuting Wei Shuting Wei, Zhiyuan Shi Shuting Wei, Zhibin Gao Zhiyuan Shi, Sheng Zhang Zhibin Gao, and Lianfen Huang Sheng Zhang

Subjects
General Computer Science
Abstract

For face anti-spoofing, many methods have been proposed to improve the security of face recognition systems. Due to distribution discrepancies among different domains, it is difficult to seek a generalized space which can generalize well to unseen attacks. In this paper, we propose a framework based on meta-learning method to improve the generalization ability of face anti-spoofing. The feature extractor is trained with forcing the distribution of real faces more compact while the distribution of fake faces is more dispersed among domains. Then we add a hybrid-domain meta learner module to simulate multiple domain shift scenarios. Moreover, we add a refined triplet mining to constrain the distance between real faces and fake ones. Multiple gradient information is integrated to optimize the feature extractor and train the model with good generalization performance to unseen attacks of various scenarios. Extensive experiments on four public datasets show that our proposed method can get better generalization ability to unseen target domain compared with state-of-the-art methods. &nbsp

Published
2022

29. Impact of CnRx Structure on Soft Error Rates of Flip-Flop Designs at 22-nm FD SOI Node

Author

Elash, Christopher J., Li, Zongru, Jin, Chen, Chen, Li, Wen, Shi-Jie, Fung, Rita, Xing, Jiesi, Shi, Shuting, Yang, Zhi Wu, and Bhuva, Bharat L.

Abstract

Embedded Silicon Germanium (eSiGe) is used in the channel region of PFET devices at the 22-nm FD SOI node. The use of eSiGe results in channel regions becoming strained, which results in better hole mobility and increased performance. However, if the active diffusion regions are too short on each side of a PFET gate, then the effect of channel strain is reduced, and performance is reduced. The Continuous Active Diffusion (CnRx) layout construct suggested by the foundry is a way to help keep channel strain present within a single-cell design. In this article, the CnRx construct is implemented in a 22-nm FD SOI test chip and soft error rates (SER) of stacked-transistor flip-flops (FFs) are shown to increase with heavy ion irradiation. The effect of channel strain on PFETs results in higher collected charges from ion strikes, and charges are more easily passed between adjacent transistors through strained channels. However, with careful schematic and layout design, these effects can be mitigated to produce both high-performance and radiation-tolerant cells using the CnRx construct.

Published
2023
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39. Engineered Hydroxyapatite Nanoadjuvants with Controlled Shape and Aspect Ratios Reveal Their Immunomodulatory Potentials

Author

Zhang, Lei, primary, Liang, Zhihui, additional, Chen, Chen, additional, Yang, Xuecheng, additional, Fu, Duo, additional, Bao, Hang, additional, Li, Min, additional, Shi, Shuting, additional, Yu, Ge, additional, Zhang, Yixuan, additional, Zhang, Caiqiao, additional, Zhang, Weiting, additional, Xue, Changying, additional, and Sun, Bingbing, additional

Published
2021
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44. Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity

Author

Zhihui Liang, Xia Xinyu, Shi Shuting, Xuehu Ma, Haoru Zhu, and Bingbing Sun

Subjects
Squalene, CpG Oligodeoxynucleotide, medicine.medical_treatment, 030231 tropical medicine, alpha-Tocopherol, MF59, Polysorbates, Adaptive Immunity, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Immune system, Immunogenicity, Vaccine, Adjuvants, Immunologic, Adjuvanticity, medicine, Animals, Humans, 030212 general & internal medicine, Clinical Trials as Topic, Vaccines, General Veterinary, General Immunology and Microbiology, business.industry, Immunogenicity, Public Health, Environmental and Occupational Health, Toxoid, Acquired immune system, Drug Combinations, Infectious Diseases, Immunology, Molecular Medicine, business, Adjuvant
Abstract

In conjugate, inactivated, recombinant, and toxoid vaccines, adjuvants are extensively and essentially used for enhanced and long-lasting protective immune responses. Depending on the type of diseases and immune responses required, adjuvants with different design strategies are developed. With aluminum salt-based adjuvants as the most used ones in commercial vaccines, other limited adjuvants, e.g., AS01, AS03, AS04, CpG ODN, and MF59, are used in FDA-approved vaccines for human use. In this paper, we review the uses of different adjuvants in vaccines including the ones used in FDA-approved vaccines and vaccines under clinical investigations. We discuss how adjuvants with different formulations could affect the magnitude and quality of adaptive immune response for optimized protection against specific pathogens. We emphasize the molecular mechanisms of various adjuvants, with the aim to establish structure-activity relationships (SARs) for designing more effective and safer adjuvants for both preventative and therapeutic vaccines.

Published
2018

45. A Single Event Transient Harden Structure for Flip-Flop with RC Filter

Author

Zhou Xiaobin, Zhou Xinjie, Guo Gang, Liu Zhun, Shi Shuting, Tao Wei, and Hui Ning

Subjects
Digital electronics, Physics, business.industry, Low-pass filter, Electrical engineering, Hardware_PERFORMANCEANDRELIABILITY, Chip, law.invention, CMOS, Single event upset, law, Hardware_INTEGRATEDCIRCUITS, Transient (oscillation), business, Radiation hardening, Flip-flop, Hardware_LOGICDESIGN
Abstract

With the feature size of CMOS technology scaling down, the IC chips is increasing every year which makes the Single Event Effect (SEE) severer in space application than before. Especially for high-frequency digital circuits, the Single Event Upset (SEU) and Single Event Transient (SET) effect could cause soft errors of data. Although dual interlocked storage cell (DICE) flip-flop has a good anti-radiation characteristic, with the frequency of circuits become higher, more soft errors appear due to Single Event Transient Effect. This paper proposed a new radiation harden structure which based on resistance-capacitance filtering for flip-flop, and we compared it with two other radiation hardened structures. The test chip was based on 0.18μm CMOS technology, and the radiation experiment was carried out in Innovative Center of Radiation Hardening Applied Technology in China Institute of Atomic Energy. The result showed the liner energy transfer (LET) of flip-flop with the new radiation harden structure is larger than 37 MeV•cm2/mg which means it could satisfied the requirements of space application.

Published
2018

48. Facile electrochemical determination of sertraline at nanomolar concentration using bimetallic MXene NbTiCTxand MWCNTs hybridized electrodes as sensing platform

Author

Tang, Nana, Wei, Yanping, He, Quanguo, Shi, Shuting, Zhou, Chuanqin, Chen, Aiting, and Liu, Jun

Abstract

A novel and facile electrochemical determination of Sertraline at nanomolar concentration using bimetallic MXene NbTiCTxand MWCNTs hybridized electrodes as sensing platforms is demonstrated. NbTiCTx/MWCNTs composites were produced by etching NbTiAlC to obtain NbTiCTx, and ultrasonically mixing this with MWCNTs. An electrochemical sensor based on NbTiCTx/MWCNTs nanocomposite modified (NbTiCTx/MWCNTs/GCE) was constructed, for use in the sensitive detection of Sertraline (SER). The successful preparation of NbTiCTx/MWCNTs and the electrochemical performance of the electrodes were verified by Scanning electron microscopy, X-ray diffraction, cyclic voltammetry and electrochemical impedance characterization methods. The experimental results show that NbTiCTx/MWCNTs/GCE can increase the SER oxidation peak current, with two good linear relationships (R2 = 0.9910 and 0.9967) between the current and the concentration of SER (5.0–10.0 μM and 10.0–100.0 μM), with a detection limit of 0.16 μM (S/N = 3). The sensor has good selectivity, repeatability, reproducibility and stability, and enables the sensitive determination of SER in human serum and urine samples of clinical biological fluids. It is believed that this work is significant and is of broad interest for work in innovative material development and biomedical applications.

Published
2024
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