1. НАМАЛЯВАНЕ ЧЕСТОТАТА И ТЕЖЕСТТА НА ОСТРИТЕ ИНФЕКЦИИ НА ГОРНИТЕ ДИХАТЕЛНИ ПЪТИЩА СЛЕД УПОТРЕБА НА ХРАНИТЕЛНА ДОБАВКА С БЕТА-ГЛЮКАН, АРАБИНОГАЛАКТАН, ЦИНК И СЕЛЕН
- Author
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Велковски, В., Насева, Е., Воденичаров, В., and Рамшев, Н.
- Subjects
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RESPIRATORY infections , *SELENIUM supplements , *DIETARY supplements , *BETA-glucans , *ARABINOGALACTAN - Abstract
The aim of the study was to evaluate the efficacy of a nutritional supplement containing a combination of Betox-93® beta-1.3/1.6-glucan 100 mg, ResistAid™ arabinogalactan 166 mg, zinc 7 mg and selenium 50 mcg, in patients 10 years of age and older on the frequency of acute upper respiratory tract infections (AURTIs) and the dynamics of their symptoms (severity). Material and methods. 242 patients with at least 3 AURTIs in the past 6 months were followed up for a period of 8 weeks during which they took the nutritional supplement at a dosage according to the product's prescription. The number of AURTIs episodes during the previous 24 weeks of observation, additionaly for the previous 8 weeks, the observation period of 8 weeks and the same 8 weeks as the observation period but the previous year were recorded. A general practitioner ambulatory assessed the intensity (severity) and dynamics of the symptoms of AURTIs during the observation period. Data are collected between September 15, 2022 and January 31, 2023. Results. Patients reported a median of 4 (IQR 3-4) episodes of AURTIs in the previous 24 weeks, of which 1 (IQR 1-2) in the last 8 weeks. The episodes of AURTIs had a median of 1 (IQR 0-1) during the followup period, which is significantly lower than the previous 8 weeks (p < 0.001). A median of 2 (IQR 2-3) AURTIs episodes were reported for the same 8 week period in the previous year, which was significantly more then the follow-up period (p < 0.001). An episode of AURTI was recorded during the follow-up period in 155 patients (64.0%), and in 13 (5.4%) also a second such episode. As expected, the assessed 10 symptoms of AURTIs showed significant improvement between days 1 and 5 in both reported frequency and severity. When evaluating the dynamics of the symptoms during the second episode of AURTI, a significant improvement was proved only in some of them, due to the small number of cases with infection. Conclusion. The results showed that patients' health is improved after supplementation with Betox-93® beta-1.3/1.6-glucan, ResistAid™ arabinogalactan, zinc and selenium dietary supplement. On one hand, the number of AURTI episodes for the observation period was significantly less than the previous 8 weeks, and on the other hand, they are significantly less than the same time interval in the previous year. In addition, a significant improvement in the presence and intensity of 10 recorded symptoms between days 1 and 5 was found for the first episode of AURTI. [ABSTRACT FROM AUTHOR]
- Published
- 2023