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169 results on '"Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE)"'

1. Chemical Sensors Based on New Polyamides Biobased on (Z) Octadec-9-Enedioic Acid and β-Cyclodextrin

Author: Philippe Guégan, Véronique Bennevault, Jean-François Feller, Matthieu Sollogoub, Mickaël Castro, Mickaël Ménand, Lisday Duarte, Sananda Nag, Elena Zaborova, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), LIMATB_UBS, Laboratoire d'Ingénierie des Matériaux de Bretagne (LIMATB), Université de Bretagne Sud (UBS)-Université de Brest (UBO)-Institut Brestois du Numérique et des Mathématiques (IBNM), Université de Brest (UBO)-Université de Brest (UBO)-Université de Bretagne Sud (UBS)-Université de Brest (UBO)-Institut Brestois du Numérique et des Mathématiques (IBNM), Université de Brest (UBO)-Université de Brest (UBO), Institut Parisien de Chimie Moléculaire (IPCM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université de Bretagne Sud (UBS)-Institut Brestois du Numérique et des Mathématiques (IBNM), Université de Brest (UBO)-Université de Brest (UBO)-Université de Brest (UBO)-Université de Bretagne Sud (UBS)-Institut Brestois du Numérique et des Mathématiques (IBNM), Université de Brest (UBO)-Université de Brest (UBO)-Université de Brest (UBO), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Polymers and Plastics, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Hydrophobic effect, chemistry.chemical_compound, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Desorption, Polymer chemistry, Materials Chemistry, Organic chemistry, Physical and Theoretical Chemistry, chemistry.chemical_classification, Conductive polymer, Nanocomposite, Cyclodextrin, Organic Chemistry, Layer by layer, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 0104 chemical sciences, [CHIM.POLY]Chemical Sciences/Polymers, Monomer, chemistry, Polyamide, 0210 nano-technology
Abstract: International audience; The synthesis of new biobased polyamides from different β-cyclodextrin monomers and the (Z) octadec-9-enedioic acid is investigated. The aim of this study is to design different sensors, having different sensibilities and selectivities to a set of various volatile organic compounds (VOC) relevant in the early detection of lung cancer. The sensors are obtained from the synthesized polyamides, using multiwalled carbon nanotubes as conductive nanofillers and a layer by layer process. The conductive polymer nanocomposites (CPC) designed from the heptakis-6-amino β-cyclodextrin and 6A,6D diamino β-cyclodextrin have a high affinity for polar protic solvents, while the CPC having a matrix based on 6A,6D diamino 2A-G,3A-G,6B,6C,6E,6F,6G nonadeca-O-benzyl-β-cyclodextrin develops hydrophobic interactions with nonpolar solvents. Due to a higher accessibility of cyclodextrin, the chemoresistive response of the hydrophilic linear polyamide CPC is larger than one of the hydrophilic branched polyamide CPC. As required, the VOC diffusion/desorption phenomenon is reversible for all the sensors.
Published: 2016
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2. Processes at nanopores and bio-nanointerfaces: general discussion

Author: Yi-Tao Long, Gourav Bhattacharya, Kim McKelvey, Wolfgang Schuhmann, Yi-Lun Ying, Lane A. Baker, Richard M. Crooks, Yanfang Wu, Chrys. O. Chikere, Michael V. Mirkin, Martin A. Edwards, Julie V. Macpherson, Paul W. Bohn, Naren Das, Henry S. White, Liping Wen, Frédéric Kanoufi, Christine Kranz, Juan Pelta, Cyril O. Ehi-Eromosele, Christophe Antoine, Hang Ren, Wojciech Nogala, Zuzanna S. Siwy, Qiong Cai, Lei Jiang, Katherine A. Willets, Zhong-Qun Tian, Jennifer A. Rudd, Hassan Alzahrani, Niklas Ermann, Sebastien Balme, Patrick R. Unwin, Richard J. Nichols, Institut Européen des membranes (IEM), Université de Montpellier (UM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Centre National de la Recherche Scientifique (CNRS), Respiratory Epidemiology and Public Health, Imperial College London-Royal Brompton Hospital-National Heart and Lung Institute [UK], Sir AlisterHardyFoundationforOceanScience, TheLaboratory,CitadelHill,PlymouthPL12PB,UK, Interfaces, Traitements, Organisation et Dynamique des Systèmes (ITODYS (UMR_7086)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Universität Ulm - Ulm University [Ulm, Allemagne], Sch Biol & Chem Sci, Queen Mary University of London (QMUL), Electrode Processes, Intitute of Physical Chemistry, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Department of Analytical Chemistry, Ruhr-Universität Bochum [Bochum], Department of Materials Sciences and Engineering, State University of New York (SUNY), Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM), Université Paris Diderot - Paris 7 (UPD7)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), and Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Nanopore, Materials science, [CHIM]Chemical Sciences, Nanotechnology, 02 engineering and technology, Physical and Theoretical Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, 0210 nano-technology, 01 natural sciences, ComputingMilieux_MISCELLANEOUS, 0104 chemical sciences
Abstract: International audience
Published: 2018
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3. From current trace to the understanding of confined media

Author: Juan Pelta, Loïc Auvray, Bruno Le Pioufle, Laurent Bacri, Jean Roman, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Systèmes et Applications des Technologies de l'Information et de l'Energie (SATIE), École normale supérieure - Cachan (ENS Cachan)-Université Paris-Sud - Paris 11 (UP11)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-École normale supérieure - Rennes (ENS Rennes)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Centre National de la Recherche Scientifique (CNRS), Institut d'Alembert (IDA), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC (UMR_7057)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Université Paris-Seine-Université Paris-Seine-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Bio-MIcroSystèmes et BioSensors (SATIE-BIOMIS), Systèmes d'Information et d'Analyse Multi-Echelles (SIAME), École normale supérieure - Rennes (ENS Rennes)-Université Paris-Sud - Paris 11 (UP11)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan)-Université Gustave Eiffel (UNIV GUSTAVE EIFFEL)-École normale supérieure - Rennes (ENS Rennes)-Université Paris-Sud - Paris 11 (UP11)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan)-Université Gustave Eiffel (UNIV GUSTAVE EIFFEL)-Systèmes et Applications des Technologies de l'Information et de l'Energie (SATIE), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan)-Université Gustave Eiffel (UNIV GUSTAVE EIFFEL), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan), and École normale supérieure - Cachan (ENS Cachan)
Subjects: chemistry.chemical_classification, Materials science, Drop (liquid), Biophysics, Complex system, Nanoparticle, Conductance, 02 engineering and technology, Surfaces and Interfaces, General Chemistry, Polymer, Polymers: From Adsorption to Translocation - Topical Issue in Memoriam Loïc Auvray (1956-2016), 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Nanopore, chemistry, Chemical physics, General Materials Science, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, 0210 nano-technology, Biotechnology
Abstract: International audience; Nanopores constitute devices for the sensing of nano-objects such as ions, polymer chains, proteins or nanoparticles. We describe what information we can extract from the current trace. We consider the entrance of polydisperse chains into the nanopore, which leads to a conductance drop. We describe the detection of these current blockades according to their shape. Finally, we explain how data analysis can be used to enhance our understanding of physical processes in confined media.
Published: 2018
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4. Corrosion at the carbon steel-clay borehole water interface under anoxic alkaline and fluctuating temperature conditions

Author: Marc Labat, Yannick Linard, Michel L. Schlegel, Eddy Foy, Cécile Blanc, Sylvie Daumas, Sophia Necib, Service d'études analytiques et de réactivité des surfaces (SEARS), Département de Physico-Chimie (DPC), CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Agence Nationale pour la Gestion des Déchets Radioactifs (ANDRA), CFG Servives (CFG Servives), CFG services, Institut méditerranéen d'océanologie (MIO), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Archéomatériaux et Prévision de l'Altération (LAPA - UMR 3685), Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M) (NIMBE UMR 3685), Institut Rayonnement Matière de Saclay (IRAMIS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut Rayonnement Matière de Saclay (IRAMIS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), ANDRA and EDF, Service d'études analytiques et de réactivité des surfaces ( SEARS ), Département de Physico-Chimie ( DPC ), Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement ( LAMBE - UMR 8587 ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université de Cergy Pontoise ( UCP ), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne ( UEVE ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Paris-Saclay, Agence Nationale pour la Gestion des Déchets Radioactifs ( ANDRA ), CFG Servives ( CFG Servives ), Institut de Recherche pour le Développement ( IRD ), Laboratoire Archéomatériaux et Prévision de l'Altération ( LAPA - UMR 3685 ), Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M) ( NIMBE UMR 3685 ), Institut Rayonnement Matière de Saclay ( IRAMIS ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ) -Institut Rayonnement Matière de Saclay ( IRAMIS ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Institut Rayonnement Matière de Saclay (IRAMIS), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)
Subjects: Materials science, Sulfide, Carbon steel, 020209 energy, General Chemical Engineering, 02 engineering and technology, engineering.material, Corrosion, Cathodic protection, Siderite, chemistry.chemical_compound, Nuclear waste repository, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Silicate minerals, 0202 electrical engineering, electronic engineering, information engineering, General Materials Science, Anoxic, chemistry.chemical_classification, Metallurgy, General Chemistry, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, Anoxic waters, 6. Clean water, Fe-silicate, chemistry, [ CHIM.MATE ] Chemical Sciences/Material chemistry, engineering, Clay, [ CHIM.ANAL ] Chemical Sciences/Analytical chemistry, 0210 nano-technology, Layer (electronics)
Abstract: International audience; Coupons of carbon steel were corroded in situ in anoxic clay porewater under slightly alkaline conditions. Sample damage was less than 1 $\mu$m for 9 months at 85 °C only, and corrosion interfaces were covered by a thin, protective layer of Fe-silicate. The damage was more significant for samples exposed to room temperature transients (up to 38 μm for two years), and the long-term surface differentiated in cathodic (Fe-silicate covered) areas and anodic crevices filled with siderite, chukanovite, $\beta$-Fe$_2$(OH)$_3$Cl, and covered by tubercles. Sulfide compounds were detected, and were related to the metabolism of sulfate-reducing prokaryotes detected by microbiological techniques.
Published: 2018
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5. Dynamics of a polyelectrolyte through aerolysin channel as a function of applied voltage and concentration

Author: Bénédicte Thiebot, Laurent Bacri, Loïc Auvray, Manuela Pastoriza-Gallego, Juan Pelta, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Matière et Systèmes Complexes (MSC (UMR_7057)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Matière et Systèmes Complexes (MSC), and ANR-17-CE09-0044,EPSILOMICS,Système de puces nanofluidiques pour le dosage de biomarqueurs en quantité epsilon dans les échantillons biologiques humains(2017)
Subjects: 0301 basic medicine, Materials science, media_common.quotation_subject, Population, Biophysics, Aerolysin, 02 engineering and technology, Asymmetry, Effective nuclear charge, 03 medical and health sciences, Exponential growth, General Materials Science, education, media_common, education.field_of_study, Surfaces and Interfaces, General Chemistry, 021001 nanoscience & nanotechnology, Polyelectrolyte, Exponential function, 030104 developmental biology, [CHIM.POLY]Chemical Sciences/Polymers, Chemical physics, 0210 nano-technology, [PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], Biotechnology, Voltage
Abstract: International audience; We describe the behaviour of a polyelectrolyte in confined geometry. The transport of a polyelectrolyte, dextran sulfate, through a recombinant protein channel, aerolysin, inserted into a planar lipid bilayer is studied as a function of applied voltage and polyelectrolyte concentration and chain length. The aerolysin pore has a weak geometry asymmetry, a high number of charged residues and the polyelectrolyte is strongly negatively charged. The resulting current blockades were characterized by short and long dwelling times. Their frequency varies exponentially as a function of applied voltage and linearly as a function of polyelectrolyte concentration. The long blockade duration decreases exponentially when the electrical force increases. The ratio of the population of short events to the one of long events decreases when the applied voltage increases and displays an exponential variation. The long residence time increases with the polyelectrolyte chain length. We measure a reduction of the effective charge of the polyelectrolyte at the pore entry and inside the channel. For a fixed applied voltage, + / - 100 mV, at both sides of the protein pore entrance, the events frequency is similar as a function of dextran sulfate concentration. The mean blockade durations are independent of polyelectrolyte concentration and are similar for both entrances of the pore and remain constant as a function of the electrical force.
Published: 2018
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6. Energy conversion at nanointerfaces: general discussion

Author: Dongping Zhan, Christine Kranz, Andrea Vezzoli, Hassan Alzahrani, Chuan Zhao, Alina Galeyeva, Wolfgang Schuhmann, Frédéric Kanoufi, Thomas J. P. Hersbach, Kim McKelvey, Richard M. Crooks, Zhugen Yang, Patrick R. Unwin, Robert Hillman, Yanfang Wu, Katherin Willets, Chrys. O. Chikere, Yi-Tao Long, Tobias Löffler, Cameron Luke Bentley, Shelley D. Minteer, Paul W. Bohn, Marc T. M. Koper, Zhong-Qun Tian, Jennifer A. Rudd, Juan Pelta, Denis Öhl, Richard J. Nichols, Cyril O. Ehi-Eromosele, Daniel Commandeur, Julie V. Macpherson, Wojciech Nogala, Andrew G. Ewing, Hang Ren, Michael V. Mirkin, Interfaces, Traitements, Organisation et Dynamique des Systèmes (ITODYS (UMR_7086)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Universität Ulm - Ulm University [Ulm, Allemagne], Sch Biol & Chem Sci, Queen Mary University of London (QMUL), Electrode Processes, Intitute of Physical Chemistry, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Department of Analytical Chemistry, Ruhr-Universität Bochum [Bochum], School of Chemistry, The University of Sydney, The University of Sydney, Université Paris Diderot - Paris 7 (UPD7)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE)
Subjects: Materials science, MEDLINE, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Engineering physics, 0104 chemical sciences, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Energy transformation, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], Physical and Theoretical Chemistry, 0210 nano-technology, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2018
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7. Electrochemical Behavior of Stainless Steels for Sudomotor Dysfunction Applications

Author: Armelle Ringuedé, Mamie Sancy, Michel Cassir, N. Vejar, José H. Zagal, X. Gonzalez, Virginie Lair, Sophie Griveau, Fethi Bedioui, Amandine Calmet, Laboratoire d'Electrochimie, Chimie des Interfaces et Modélisation pour l'Energie (LECIME - UMR 7575) (LECIME), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC), Laboratoire d'Electrochimie et de Chimie Analytique (LECA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Unité de pharmacologie chimique et génétique et d'imagerie (UPCGI - UMR 8151 / UMR_S 1022 ), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Materials science, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Electrochemistry, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, Dielectric spectroscopy, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Composite material, 0210 nano-technology, ComputingMilieux_MISCELLANEOUS, Sudomotor dysfunction
Abstract: AISI 304L is used in Sudoscan(TM) technology (Impeto Medical Inc.) for the early diagnosis of small fiber neuropathy caused by type-2 diabetes or cystic fibrosis. In a recent paper, several substitute electrodes were analyzed, among which the biocompatib
Published: 2018
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8. The impact of paper constituents on the efficiency of mechanical strengthening by polyaminoalkylalkoxysilanes

Author: Isabelle Fabre-Francke, Bertrand Lavédrine, Hervé Cheradame, Odile Fichet, Anne-Laurence Dupont, Sabrina Paris-Lacombe, Camille Piovesan, Laboratoire de Physico-chimie des Polymères et des Interfaces (LPPI), Fédération INSTITUT DES MATÉRIAUX DE CERGY-PONTOISE (I-MAT), Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Centre de Recherche pour la Conservation des Collections (CRCC), Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche sur la Conservation (CRC ), Muséum national d'Histoire naturelle (MNHN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN)-Ministère de la Culture et de la Communication (MCC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), CY Cergy Paris Université (CY)-CY Cergy Paris Université (CY), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE)
Subjects: Paper, Copolymer networks, Materials science, Polymers and Plastics, Binary mixtures, Alkalinity, Tensile resistance, 02 engineering and technology, Pulp, engineering.material, Plasticity, 010402 general chemistry, 01 natural sciences, Lignin, Inter-fiber bonding, chemistry.chemical_compound, Paper Making, Aminoalkylalkoxysilane copolymer, Deacidification, Tensile Strength, Ultimate tensile strength, Chemical pulp, Chemical Treatment, Composite material, Chemical Pulping, Papermaking, Pulp (paper), Copolymers, Chemical bonds, Additives, Sizing (finishing operation), 021001 nanoscience & nanotechnology, Fillers, Sizing, Folding endurance, 0104 chemical sciences, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Mechanical strengthening, [CHIM.POLY]Chemical Sciences/Polymers, chemistry, Mechanical pulp, Lignins, engineering, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], 0210 nano-technology
Abstract: International audience; The aim of the research was to evaluate the influence of certain components of paper such as lignin and papermaking additives (fillers and sizing) on the efficiency of a recently proposed treatment for simultaneous deacidification and mechanical strengthening with polyaminosiloxane copolymer networks. Mixed mechanical and chemical pulp papers containing various additives were treated with aminoalkylalkoxysilanes (AAAS) by immersion or by spray. Upon treatment, the deposited alkaline reserve varied from 0.34 to 1.14 mol kg −1 . For all the papers, copolymers formed from binary mixtures of a di- and a tri-functional AAAS provided the best improvement in the mechanical properties, i.e. in the tensile strength and the folding endurance, indicating an increase in the interfiber bonding energy and in the paper flexibility and plasticity, respectively. It was found that fillers had no influence while sizing hampered the efficiency of the treatment. The presence of mechanical pulp was shown to have a significant impact on the effect of the treatments as well by increasing the tensile resistance more than the folding endurance, indicating an increase in the paper rigidity. This observation was attributed to the response of lignin to the treatment.
Published: 2017
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9. Functionalized Solid-State Nanopore Integrated in a Reusable Microfluidic Device for a Better Stability and Nanoparticle Detection

Author: Bruno Le Pioufle, Gilles Patriarche, Juan Pelta, Jean Roman, Olivier Français, Nathalie Jarroux, Laurent Bacri, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Centre de Nanosciences et de Nanotechnologies [Marcoussis] (C2N), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Electronique, Systèmes de communication et Microsystèmes (ESYCOM), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Paris-Est Marne-la-Vallée (UPEM)-ESIEE Paris, Systèmes d'Information et d'Analyse Multi-Echelles (SATIE-SIAME), Systèmes et Applications des Technologies de l'Information et de l'Energie (SATIE), École normale supérieure - Cachan (ENS Cachan)-Université Paris-Sud - Paris 11 (UP11)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-École normale supérieure - Rennes (ENS Rennes)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan)-Université Paris-Sud - Paris 11 (UP11)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-École normale supérieure - Rennes (ENS Rennes)-Université de Cergy Pontoise (UCP), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Paris-Est Marne-la-Vallée (UPEM)-ESIEE Paris, Bio-MIcroSystèmes et BioSensors (SATIE-BIOMIS), Systèmes d'Information et d'Analyse Multi-Echelles (SIAME), Université Paris-Seine-Université Paris-Seine-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan)-Université Paris-Sud - Paris 11 (UP11)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-École normale supérieure - Rennes (ENS Rennes)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Centre National de la Recherche Scientifique (CNRS)-Systèmes et Applications des Technologies de l'Information et de l'Energie (SATIE), Université Paris-Seine-Université Paris-Seine-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), École normale supérieure - Rennes (ENS Rennes)-Université Paris-Sud - Paris 11 (UP11)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan)-Université Gustave Eiffel (UNIV GUSTAVE EIFFEL)-École normale supérieure - Rennes (ENS Rennes)-Université Paris-Sud - Paris 11 (UP11)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan)-Université Gustave Eiffel (UNIV GUSTAVE EIFFEL)-Systèmes et Applications des Technologies de l'Information et de l'Energie (SATIE), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan)-Université Gustave Eiffel (UNIV GUSTAVE EIFFEL), and Université Paris-Est Marne-la-Vallée (UPEM)-ESIEE Paris-Conservatoire National des Arts et Métiers [CNAM] (CNAM)
Subjects: chemistry.chemical_classification, polymer brush, Materials science, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, Biomolecule, Microfluidics, Nanoparticle, Nanotechnology, 02 engineering and technology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Polymer brush, 01 natural sciences, 0104 chemical sciences, solid-state nanopore, Nanopore, Membrane, chemistry, Ionic conductance, General Materials Science, Nanorod, nanopore functionalization, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, 0210 nano-technology
Abstract: International audience; Electrical detection based on single nanopores is an efficient tool to detect biomolecules, particles and study their morphology. Nevertheless the surface of the solid-state membrane supporting the nanopore should be better controlled. Moreover, nanopore should be integrated within microfluidic architecture to facilitate control fluid exchanges. We built a reusable microfluidic system integrating a decorated membran, rendering the drain and refill of analytes and buffers easier. This process enhances strongly ionic conductance of the nanopore and its lifetime. We highlight the reliability of this device by detecting gold nanorods and spherical proteins.
Published: 2017
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10. Pitting corrosion modelling by means of a stochastic cellular automata-based model

Author: Annie Chaussé, Cristian Felipe Pérez-Brokate, Dung Di Caprio, Jacques de Lamare, Damien Féron, Service de la Corrosion et du Comportement des Matériaux dans leur Environnement (SCCME), Département de Physico-Chimie (DPC), CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut de Recherche de Chimie Paris (IRCP), Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Ministère de la Culture (MC)-Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ministère de la Culture (MC)
Subjects: Cellular automata, Materials science, 020209 energy, General Chemical Engineering, Stochastic cellular automata, Pitting, 02 engineering and technology, Electrolyte, Corrosion, Cathodic protection, Electrolytes, Charge transfer, Stochastic cellular automaton, Cathodic reactions, Acid corrosion, 0202 electrical engineering, electronic engineering, information engineering, Pitting corrosion, passivity, General Materials Science, [PHYS.COND]Physics [physics]/Condensed Matter [cond-mat], ComputingMilieux_MISCELLANEOUS, Macroscopic methods, Electric connectors, Modelling studies, Mesoscopic physics, Stochastic systems, Metallurgy, General Chemistry, Mechanics, 021001 nanoscience & nanotechnology, Random walk, Cellular automaton, Corrosion modelling, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Stochastic models, Electric connections, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], 0210 nano-technology
Abstract: International audience; We use stochastic Cellular Automata (CA) based modelling for corrosion studies at a mesoscopic scale. Physico-chemical phenomena that cannot be satisfactorily described by standard deterministic and macroscopic methods are represented. Materials are described by a 3D lattice where each cell has a state. Phenomena are represented as simple transition rules defining the evolution of the cells with given probabilities. Diffusion in the electrolyte is modelled as a random walk. Charge transfer corresponds to simultaneous anodic and cathodic reactions with special emphasis on their electric connection ensuring electric balance. We study evolution of pitting corrosion in terms of pit size morphology and acidity of the electrolyte. Starting from metal covered by a passive layer with a single defect, a cavity starts growing inside the metal and notably the exterior basic environment delays the dissolution of the protective passive layer. Results are in accordance with published experimental results on pitting corrosion.
Published: 2017
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11. On the development of polarizable and Lennard-Jones force fields to study hydration structure and dynamics of actinide(III) ions based on effective ionic radii

Author: Valentina Migliorati, Riccardo Spezia, Paola D'Angelo, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Dipartimento di Chimica, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and Università degli Studi di Roma 'La Sapienza' [Rome]
Subjects: hydration, rare earth elements, water molecules, Ionic radius, Solvation, General Physics and Astronomy, chemistry.chemical_element, 02 engineering and technology, Actinide, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Force field (chemistry), 0104 chemical sciences, Ion, Lennard-Jones potential, Berkelium, chemistry, Polarizability, Chemical physics, Physics::Atomic and Molecular Clusters, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], Physical and Theoretical Chemistry, Atomic physics, 0210 nano-technology
Abstract: International audience; In this contribution, we show how it is possible to develop polarizable and non-polarizable force fields to study hydration properties of a whole chemical series based on atomic properties such as ionic radii. In particular, we have addressed the actinide(III) ion series, from U3+ to Cf3+, for which X-ray absorption data and effective ionic radii are available. A polarizable force field has been re-parameterized improving the original one [M. Duvail et al., J. Chem. Phys. 135, 044503 (2011)] which was based on solid state ionic radii. The new force field does not depend on solid state properties but directly on the liquid phase ones, and it can be used to study these ions in liquid water without any ambiguity. Furthermore, we have shown that it is possible to parameterize also a non-polarizable potential using standard Lennard-Jones and Coulombic forces, which can be transferred to other systems in condensed phase. The structural and dynamical properties of these two force fields are compared to each other and with data available in the literature, providing a good agreement. Moreover, we show the comparison with experimental X-ray absorption data that are very well reproduced by both force fields.
Published: 2017
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12. How Does CeIII Nitrate Dissolve in a Protic Ionic Liquid? A Combined Molecular Dynamics and EXAFS Study

Author: Valentina Migliorati, Riccardo Spezia, Alessandra Serva, Paola D'Angelo, Dipartimento di Chimica, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Università degli Studi di Roma 'La Sapienza' [Rome], Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA)
Subjects: Lanthanoid ions, Cerium compounds, Metal ions in aqueous solution, Inorganic chemistry, 02 engineering and technology, Molecular dynamics, 010402 general chemistry, Ligands, 01 natural sciences, Catalysis, Ion, chemistry.chemical_compound, ethylammonium nitrate, EXAFS spectroscopy, icosahedral structure, lanthanoid ions, molecular dynamics, Chemistry (all), Ethylammonium nitrate, Metal ions, X ray absorption, Coordination geometry, Nitrates, Extended X-ray absorption fine structure, Molecular dynamics simulations, Organic Chemistry, Icosahedral structure, Extended X ray absorption fine structure spectroscopy, General Chemistry, Bidentate ligands, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Ionic liquids, Solvation shell, Protic ionic liquids, Extended Xray absorption fine structure (EXAFS) spectroscopies, chemistry, Heavy metals, Existing structure, Ionic liquid, Physical chemistry, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], 0210 nano-technology, Angular distribution, Distribution functions
Abstract: International audience; A diluted solution of Ce(NO3)3 in the protic ionic liquid (IL) ethylammonium nitrate (EAN) was investigated using molecular dynamics (MD) simulations and extended X-ray absorption fine structure (EXAFS) spectroscopy. For the first time polarizable effects were included in the MD force field to describe a heavy metal ion in a protic IL, but, unlike water, they were found to be unessential. The CeIII ion first solvation shell is formed by nitrate ions arranged in an icosahedral structure, and an equilibrium between monodentate and bidentate ligands is present in the solution. By combining distance and angular distribution functions it was possible to unambiguously identify this peculiar coordination geometry around the ions dissolved in solution. The metal ions are solvated within the polar domains of the EAN nanostructure and the dissolved salt induces almost no reorganization of the pre-existing structure of EAN upon solubilization.
Published: 2017
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13. Elasticity, Adhesion, and Tether Extrusion on Breast Cancer Cells Provide a Signature of Their Invasive Potential

Author: Sid Labdi, Bénédicte Thiebot, Juan Pelta, Georgiy Smolyakov, Childérick Séverac, Clément Campillo, Etienne Dague, Institut des Technologies Avancées en sciences du Vivant (ITAV), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Équipe Ingénierie pour les sciences du vivant (LAAS-ELIA), Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse 1 Capitole (UT1)-Université Toulouse - Jean Jaurès (UT2J), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse 1 Capitole (UT1)-Université Toulouse - Jean Jaurès (UT2J)-Institut National Polytechnique (Toulouse) (Toulouse INP), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées
Subjects: 0301 basic medicine, Materials science, Cell, Nanotechnology, 02 engineering and technology, Metastasis, 03 medical and health sciences, medicine, cancer, metastasis, General Materials Science, Elasticity (economics), [PHYS.MECA.BIOM]Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph], [SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials, single-cell force spectroscopy, Elastic modulus, ComputingMilieux_MISCELLANEOUS, invasivity, biology, Force spectroscopy, tethers, 021001 nanoscience & nanotechnology, medicine.disease, nanomechanics, Fibronectin, adhesion, 030104 developmental biology, medicine.anatomical_structure, Cancer cell, Biophysics, biology.protein, Extrusion, [SDV.IB]Life Sciences [q-bio]/Bioengineering, AFM, 0210 nano-technology
Abstract: International audience; We use single-cell force spectroscopy to compare elasticity, adhesion, and tether extrusion on four breast cancer cell lines with an increasing invasive potential. We perform cell attachment/detachment experiments either on fibronectin or on another cell using an atomic force microscope. Our study on the membrane tether formation from cancer cells show that they are easier to extrude from aggressive invasive cells. Measured elastic modulus values confirm that more invasive cells are softer. Moreover, the adhesion force increases with the invasive potential. Our results provide a mechanical signature of breast cancer cells that correlates with their invasivity.
Published: 2016
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14. Three dimensional discrete stochastic model of occluded corrosion cell

Author: Cristian Felipe Pérez-Brokate, Annie Chaussé, Damien Féron, Jacques de Lamare, Dung Di Caprio, Service de la Corrosion et du Comportement des Matériaux dans leur Environnement (SCCME), Département de Physico-Chimie (DPC), CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut de Recherche de Chimie Paris (IRCP), Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ministère de la Culture (MC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Materials science, Stochastic modelling, 020209 energy, General Chemical Engineering, [SDV]Life Sciences [q-bio], 02 engineering and technology, Electrolyte, Cathodic protection, Corrosion, Electrolytes, Cathodic reactions, Acid corrosion, 0202 electrical engineering, electronic engineering, information engineering, Galvanic cell, Uniform and localized corrosion, General Materials Science, Diffusion (business), [PHYS.COND]Physics [physics]/Condensed Matter [cond-mat], ComputingMilieux_MISCELLANEOUS, Modelling studies, Three dimensional (3-D) modeling, Mesoscopic physics, Stochastic systems, Metallurgy, General Chemistry, Mechanics, 021001 nanoscience & nanotechnology, Anode, C. Passivity, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Stochastic models, Localized corrosion, Discrete stochastic models, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], 0210 nano-technology, Electric balance
Abstract: International audience; We present a stochastic three dimensional (3D) model for corrosion at a mesoscopic scale. The competition between uniform and localized corrosion is studied, with special emphasis given to the connection between the anodic and cathodic reactions. Even if the reactions happen at different places, they are linked and occur simultaneously, maintaining an electric balance. We focused on the particular case of an occluded corrosion on a metal covered by a non reactive layer, where two growth regimes are evidenced and controlled by the diffusion of species in the electrolyte.
Published: 2016
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15. Cyclodextrin‐cobalt (II) molecule‐ion pairs as precursors to active Co3O4/ZrO2 catalysts for the complete oxidation of formaldehyde: Influence of the cobalt source

Author: Lei Bai, Maryam Safariamin, Frédéric Wyrwalski, Jean-François Lamonier, Rudina Bleta, Cédric Przybylski, Eric Monflier, Anne Ponchel, Anhui University [Hefei], Unité de Catalyse et de Chimie du Solide - Site Artois (UCCS Artois), Université d'Artois (UA)-Université de Lille, Sciences et Technologies-Ecole Centrale de Lille-Ecole Nationale Supérieure de Chimie de Lille (ENSCL)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), UCCS Équipe Catalyse Supramoléculaire, Unité de Catalyse et Chimie du Solide - UMR 8181 (UCCS), Centrale Lille Institut (CLIL)-Université d'Artois (UA)-Centrale Lille-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Lille-Centrale Lille Institut (CLIL)-Université d'Artois (UA)-Centrale Lille-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Lille, Centrale Lille Institut (CLIL)-Université d'Artois (UA)-Centrale Lille-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Lille, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Université d'Artois (UA)-Centrale Lille-Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université d'Artois (UA)-Centrale Lille-Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Université d'Artois (UA)-Centrale Lille-Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Subjects: inorganic chemicals, Inorganic chemistry, Formaldehyde, chemistry.chemical_element, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Catalysis, chemistry.chemical_compound, Dynamic light scattering, Cobalt catalysts, Organic chemistry, Molecule, Cyclodextrin, [CHIM]Chemical Sciences, Physical and Theoretical Chemistry, Cobalt oxide, chemistry.chemical_classification, Chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Supramolecular complex, Zirconia, 0210 nano-technology, Dispersion (chemistry), Formaldehyde oxidation, Cobalt
Abstract: International audience; The present paper reports on the use of β-cyclodextrin (β-CD) during the preparation of zirconia-supported cobalt oxide catalysts by impregnation and their performances in the complete oxidation of formaldehyde. The effect of β-CD was carefully characterized at different stages of the preparation with respect to three cobalt precursors (i.e. cobalt nitrate, acetate and acetylacetonate) by UV–Vis spectroscopy, dynamic light scattering, mass spectrometry, TG-MS analysis, X-ray diffraction and temperature-programmed reduction. It was found that β-CD had a strong impact on the final properties of catalysts, both in terms of reducibility and dispersion of active species. The results were rationalized to the occurrence of complexation between the cobalt precursor and β-CD and highlighted the pivotal role played by the counteranion. The best combination was obtained using cobalt nitrate with a β-CD/cobalt ratio 0.1 while the beneficial impact of cyclodextrins for the impregnation method was successfully extended to other cyclodextrins (α-CD and γ-CD).
Published: 2016
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16. Deciphering of polycationic carbohydrate based non‐viral gene delivery agents by ESI‐LTQ‐Orbitrap using CID/HCD pairwise tandem mass spectrometry

Author: Cédric Przybylski, Véronique Bonnet, Juan M. Benito, Carmen Ortiz Mellet, José M. García Fernández, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Instituto de Investigaciones Químicas (IIQ), Universidad de Sevilla-Consejo Superior de Investigaciones Científicas [Spain] (CSIC), Laboratoire de Glycochimie, des Antimicrobiens et des Agroressources (LG2A) UMR7378 UPJV/CNRS, Université de Picardie Jules Verne (UPJV), Universidad de Sevilla, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Universidad de Sevilla / University of Sevilla-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Laboratoire de Glycochimie, des Antimicrobiens et des Agro-ressources - UMR CNRS 7378 (LG2A ), Université de Picardie Jules Verne (UPJV)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Universidad de Sevilla / University of Sevilla, Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC)-Universidad de Sevilla, and Institut de Chimie du CNRS (INC)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Collision-induced dissociation, Chemistry, General Chemical Engineering, Context (language use), 02 engineering and technology, General Chemistry, Computational biology, Transfection, 010402 general chemistry, 021001 nanoscience & nanotechnology, Tandem mass spectrometry, Orbitrap, Mass spectrometry, 01 natural sciences, Combinatorial chemistry, 3. Good health, 0104 chemical sciences, law.invention, chemistry.chemical_compound, law, Sense (molecular biology), [CHIM]Chemical Sciences, 0210 nano-technology, DNA
Abstract: For almost three decades, gene therapy has been gaining interest to efficiently treat some severe diseases. In such context, the discovery of an efficient non-viral gene carrier to deliver genetic material into targeted cell nuclei is of prime importance. Numerous synthetic vectors that have been designed exhibit high transfection efficiency but also suffer from extensive cytotoxicity, thus justifying efforts to synthesize more bio-compatible ones, for example, with carbohydrate scaffolds. In this sense, cyclodextrins (CDs) are well known to present low to very low cytotoxicity in humans and have potential, after polycationization, to serve as suitable compaction/transfection agents for RNA/DNA. However, such polycationic CDs must be accurately characterized to establish a straightforward structure¿biological activity relationship which is guided by the nitrogen/phosphorus ratio (N/P). In the study herein, we demonstrated that electrospray-(tandem) mass spectrometry (ESI-(MS)MS) combining Collision Induced Dissociation (CID) and Higher Collision induced Dissociation (HCD) is a useful tool for such synthetic agent characterization. The suitability of CID/HCD pairwise combination was investigated for the structural deciphering of five representative members of a polycationic cyclodextrin library. Our approach allows for easy access to content, type and localisation of amino groups thereby offering a useful tool to correlate the synthetic delivery agent with effective compaction of oligo-/polynucleotides.
Published: 2016
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17. Design of Laccase–Metal Organic Framework-Based Bioelectrodes for Biocatalytic Oxygen Reduction Reaction

Author: Christian Serre, Saad Sene, Christine Mousty, Ludovic Legrand, Annie Chaussé, Snehangshu Patra, Nathalie Steunou, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Lavoisier de Versailles (ILV), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie de Clermont-Ferrand (ICCF), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Sigma CLERMONT (Sigma CLERMONT)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Laccase, oxygen reduction reaction, ABTS, bioelectrocatalysis, Chemistry, MIL-100(Fe), Inorganic chemistry, 02 engineering and technology, Porosimetry, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, MOFs, 0104 chemical sciences, laccase, chemistry.chemical_compound, Electrode, Molecule, Ionic conductivity, [CHIM]Chemical Sciences, General Materials Science, Metal-organic framework, 0210 nano-technology, Mesoporous material
Abstract: International audience; Laccase in combination with 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) as a mediator is a well-known bioelectrocatalyst for the 4-electron oxygen reduction reactions (ORR). The present work deals with the first exploitation of mesoporous iron(III) trimesate-based metal organic frameworks (MOF) MIL-100(Fe) (MIL stands for materials from Institut Lavoisier) as a new and efficient immobilization matrix of laccase for the building up of biocathodes for ORR. First, the immobilization of ABTS in the pores of the MOF was studied by combining micro-Raman spectroscopy, X-ray powder diffraction (XRPD), and N2 porosimetry. The ABTS-MIL-100(Fe)-based modified electrode presents excellent properties in terms of charge transfer kinetics and ionic conductivity as well as a very stable and reproducible electrochemical response, showing that MIL-100(Fe) provides a suitable and stabilizing microenvironment for electroactive ABTS molecules. In a second step, laccase was further immobilized on the MIL-100(Fe)-ABTS matrix. The Lac-ABTS-MIL-100(Fe)-CIE bioelectrode presents a high electrocatalytic current density of oxygen reduction and a reproducible electrochemical response characterized by a high stability over a long period of time (3 weeks). These results constitute a significant advance in the field of laccase-based bioelectrocatalysts for ORR. According to our work, it appears that the high catalytic efficiency of Lac-ABTS-MIL-100(Fe) for ORR may result from a synergy of chemical and catalytic properties of MIL-100(Fe) and laccase.
Published: 2016
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18. Consolidation of artificially degraded polyurethane ester foam with aminoalkylalkoxysilanes

Author: Agnès Lattuati-Derieux, Jean-Baptiste d'Espinose de Lacaillerie, Hervé Cheradame, Bertrand Lavédrine, Eleonora Pellizzi, Centre de Recherche pour la Conservation des Collections (CRCC), Centre de Recherche sur la Conservation (CRC ), Muséum national d'Histoire naturelle (MNHN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Sciences et Ingénierie de la Matière Molle (SIMM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-PSL Research University (PSL)-ESPCI ParisTech-Université Pierre et Marie Curie - Paris 6 (UPMC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Polyurethane, Materials science, Polymers and Plastics, Scanning electron microscope, Aminoalkylalkoxysilanes, 02 engineering and technology, Conservation, 010402 general chemistry, 01 natural sciences, chemistry.chemical_compound, Materials Chemistry, Magic angle spinning, Composite material, Fourier transform infrared spectroscopy, chemistry.chemical_classification, Contemporary art, Foams, Polymer, Artificial degradation, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Compression (physics), 0104 chemical sciences, Reinforcement, Monomer, [CHIM.POLY]Chemical Sciences/Polymers, chemistry, Polymerization, Mechanics of Materials, [SDE]Environmental Sciences, 0210 nano-technology
Abstract: International audience; Museum artifacts made of polyurethane ester foam are frequently affected by conservation issues mainly related to the loss of their mechanical properties. Modification of mechanical properties often leads to structure crumbling and in some cases to the loss of the entire artifact. A previous study evaluated the possibility to reinforce new flexible industrial polyurethane ester foam with aminoalkylalkoxysilane (AAAS) based treatments. In this paper AAAS are applied on artificially degraded polyurethane ester foam to investigate the possibility to reinforce already degraded objects. Two AAAS, the 3-Aminopropylmethyldiethoxysilane and the N-(2-Aminoethyl)-3-aminopropylmethyldimethoxysilane have been tested. AAAS solutions at different concentrations have been used to apply the monomers on the foam samples by immersion. Mechanical properties have been studied by Compression Force Deflection Test, which shows that after AAAS treatment the resistance of the foam to compression improves and the cell collapse is prevented. The color of the samples, before and after consolidation, has been monitored to assess the impact of the treatment on the visual aspect of the foam. AAAS distribution in the thickness of the samples has been investigated by Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). Silicon Magic angle spinning nuclear magnetic resonance (29Si MAS NMR) has been used to confirm AAAS polymerization and to evaluate its average polymer chain length. 29Si MAS NMR has also been used to investigate the behavior of AAAS polymers in time by analyzing four years old reinforced samples. The results highlighted the stability of the poly-AAAS chains after four years of natural aging.
Published: 2016
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19. Evaluation of the Effect of Chemical or Enzymatic Synthesis Methods on Biodegradability of Polyesters

Author: Bruno Baréa, Philippe Guégan, Fabio Ziarelli, Yann Raoul, Laurent Goujard, Nathalie Jarroux, Pierre-Jean Roumanet, E. Ferre, Jean Petit, Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ingénierie des Agro-polymères et Technologies Émergentes (UMR IATE), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Organisation Nationale Interprofessionnelle des Graines et Fruits Oléagineux (ONIDOL), ONIDOL, Fédération des Sciences Chimiques de Marseille (FRSCM), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut Parisien de Chimie Moléculaire (IPCM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UMR237-Aix Marseille Université (AMU)-Avignon Université (AU), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Institut National de la Recherche Agronomique (INRA), École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Institut National de la Recherche Agronomique (INRA), and École Centrale de Marseille (ECM)-Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Polymers and Plastics, Biosynthèse, 02 engineering and technology, Catalyse, Biodégradation, 01 natural sciences, Biodégradabilité, chemistry.chemical_compound, Materials Chemistry, Organic chemistry, Candida, chemistry.chemical_classification, 000 - Autres thèmes, Synthèse chimique, Polymer, 021001 nanoscience & nanotechnology, Enzyme immobilisée, 6. Clean water, Polyester, Biodegradability, visual_art, visual_art.visual_art_medium, Activité enzymatique, 0210 nano-technology, Acide oléique, Glycérol, Environmental Engineering, Materials science, 010402 general chemistry, Elastomer, Enzyme catalysis, Catalysis, Metal, Glycerol, [CHIM]Chemical Sciences, Q60 - Traitement des produits agricoles non alimentaires, Biodegradation, Enzymatic polyesters, 0104 chemical sciences, chemistry, Estérification, Chemical polyesters
Abstract: International audience; This work compares the biodegradability of polyesters produced by an esterification reaction between glycerol and oleic di-acid (D 18:1) issued from green chemical pathways, via either classical thermo-chemical methods, or an enzymatic method using the immobilized lipase of Candida antartica B (Novozym 435). An elastomeric polymer synthesized by enzymatic catalysis is more biodegradable than an elastomeric thermo-chemical polyester synthesized by a standard chemical procedure. This difference lies in percentage of the dendritic motifs, in values of the degree of substitution, and certainly in cross-links inducing an hyper-branched structure less accessible to the lipolytic enzymes in a waste treatment plant. However, when the elastomeric polymer synthesized by enzymatic catalysis is processed at high temperature as required for certain industrial applications, it presents an identical rate of biodegradation than the chemical polyester. The advantages of the thermo-chemical methods are greater speed and lower cost. Enzymatic synthesis appears be suited to producing polyesters, devoid of metallic catalysts, which must be used without processing at high temperature to keep a high biodegradability.
Published: 2016
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20. Dynamic characterization of inter and intralamellar domains of Cobalt-based layered double hydroxides upon electrochemical oxidation

Author: Fabrice Leroux, Ozlem Sel, Christine Taviot-Guého, Fatemeh Razzaghi, Ulla Gro Nielsen, Hubert Perrot, Erik Elkaim, Nicholai Daugaard Jensen, Christine Mousty, Sophie Peulon, Pierre Vialat, Institut de Chimie de Clermont-Ferrand (ICCF), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Sigma CLERMONT (Sigma CLERMONT)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Interfaces et Systèmes Electrochimiques (LISE), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), University of Southern Denmark (SDU), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Layered double hydroxides, General Chemical Engineering, Diffusion, Inorganic chemistry, Analytical chemistry, chemistry.chemical_element, 02 engineering and technology, Electrolyte, engineering.material, 010402 general chemistry, Electrochemistry, 01 natural sciences, Redox, Materials Chemistry, [CHIM]Chemical Sciences, Voltammetry, General Chemistry, Quartz crystal microbalance, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Electrochemical oxidation, chemistry, engineering, [CHIM.OTHE]Chemical Sciences/Other, 0210 nano-technology, Cobalt
Abstract: International audience; This work investigated in situ changes in the structure of the layered double hydroxides (LDH) during electrochemical processes as well as followed the ion motion related to the charge balancing process. Electrogravimetric measurements, using an electrochemical quartz crystal microbalance (EQCM), allowed one to monitor simultaneously changes in current and in microbalance frequency when electroactive films of Co2Al–NO3 LDH were subjected to voltammetry potential cycling in alkaline solutions (0.1 M COH, C = Li+, Na+, and K+). EQCM results showed a strong dependence of the electrochemical process on the nature of electrolyte cations. Operando X-ray diffraction measurements, carried out during potential cycling of Co2Al–NO3 films in KOH electrolyte, showed the diffusion of OH– species gradually replacing NO3–. Total X-ray scattering experiments recorded ex situ on Co2Al–NO3 after successive oxidation and reduction revealed the presence of a high level of structural disorders even in the pristine material. A quantitative analysis of the local distribution of the cations by the analysis of the pair distribution functions highlighted the presence of different Co sites with distinct modification of Co–OH distances in the first coordination shells after oxidation/reduction.
Published: 2016
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21. Bimodal Acidity at the Amorphous Silica/Water Interface

Author: Marialore Sulpizi, Frederik Tielens, Dominique Costa, Morgane Pfeiffer-Laplaud, Marie-Pierre Gaigeot, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche de Chimie Paris (IRCP), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), Laboratoire de Chimie de la Matière Condensée de Paris (LCMCP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Collège de France (CdF (institution))-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), HRLS (Hermit) [2DSFG], Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), Université Pierre et Marie Curie - Paris 6 (UPMC)-Collège de France (CdF)-Centre National de la Recherche Scientifique (CNRS), Johannes Gutenberg - Universität Mainz (JGU), Chemistry, Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), and Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF (institution))-Institut de Chimie du CNRS (INC)
Subjects: Siloxanes, Chemistry, Acidity, Interfaces, Thermodynamic integration, Silica, 02 engineering and technology, [CHIM.MATE]Chemical Sciences/Material chemistry, Noncovalent, interactions, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Amorphous solid, Ab initio molecular dynamics, General Energy, Deprotonation, Computational chemistry, Chemical physics, Physical and Theoretical Chemistry, Amorphous silica, 0210 nano-technology
Abstract: International audience; Understanding the microscopic origin of the acid base behavior of mineral surfaces in contact with water is still a challenging task, for both the experimental and the theoretical communities. Even for a relatively simple material, such as silica, the origin of the bimodal acidity behavior is still a debated topic. In this contribution we calculate the acidity of single sites on the humid silica surface represented by a model for the hydroxylated amorphous surface. Using a thermodynamic integration approach based on ab initio molecular dynamics, we identify two different acidity values. In particular, some convex geminals and some type of vicinals are very acidic (pKa = 2.9 and 2.1, respectively) thanks to a special stabilization of their deprotonated forms. This recalls the behavior of the out-of-plane silanols on the crystalline (0001) alpha-quartz surface, although the acidity here is even stronger. On the contrary, the concave geminals and the isolated groups present a quite high pKa (8.9 and 10.3, respectively), similar to the one of silicic acid in liquid water.
Published: 2015
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22. Stalking Higher Energy Conformers on the Potential Energy Surface of Charged Species

Author: Alvaro Cimas, Vincent Brites, Marie-Pierre Gaigeot, Riccardo Spezia, James M. Lisy, Nicolas Sieffert, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Département de Chimie Moléculaire (DCM), Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), University of Illinois at Urbana-Champaign [Urbana], University of Illinois System, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Joseph Fourier - Grenoble 1 (UJF), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Université Joseph Fourier - Grenoble 1 (UJF)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Time Factors, Surface Properties, Nanotechnology, 02 engineering and technology, Lithium, Molecular Dynamics Simulation, 010402 general chemistry, Kinetic energy, 01 natural sciences, Cluster (physics), Physical and Theoretical Chemistry, Conformational isomerism, Internal energy, Chemistry, Water, 021001 nanoscience & nanotechnology, Potential energy, Transition state, 0104 chemical sciences, Computer Science Applications, Kinetics, Chemical physics, Potential energy surface, Quantum Theory, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], 0210 nano-technology, Isomerization
Abstract: International audience; Combined theoretical DFT-MD and RRKM methodologies and experimental spectroscopic infrared predissociation (IRPD) strategies to map potential energy surfaces (PES) of complex ionic clusters are presented, providing lowest and high energy conformers, thresholds to isomerization, and cluster formation pathways. We believe this association not only represents a significant advance in the field of mapping minima and transition states on the PES but also directly measures dynamical pathways for the formation of structural conformers and isomers. Pathways are unraveled over picosecond (DFT-MD) and microsecond (RRKM) time scales while changing the amount of internal energy is experimentally achieved by changing the loss channel for the IRPD measurements, thus directly probing different kinetic and isomerization pathways. Demonstration is provided for Li(+)(H2O)3,4 ionic clusters. Nonstatistical formation of these ionic clusters by both direct and cascade processes, involving isomerization processes that can lead to trapping of high energy conformers along the paths due to evaporative cooling, has been unraveled.
Published: 2015
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23. FIB patterning of dielectric, metallized and graphene membranes: A comparative study

Author: James Yates, Bérangère Toury, Philippe Guégan, E. Bourhis, A. Morin, E. Tarnaud, Jérôme Mathé, Ali Madouri, Jacques Gierak, Quentin Wilmart, Xavier Lafosse, Stéphane Guilet, Fabien Montel, Gilles Patriarche, Christian Ulysse, Loïc Auvray, A. Hemamouche, Bernard Plaçais, Laboratoire de photonique et de nanostructures (LPN), Centre National de la Recherche Scientifique (CNRS), Laboratoire des Multimatériaux et Interfaces (LMI), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Chimie des polymères (LCP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut Parisien de Chimie Moléculaire (IPCM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Pierre Aigrain (LPA), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Instituto de Tecnologia Química e Biológica António Xavier (ITQB), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC (UMR_7057)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Parisien de Chimie Moléculaire (IPCM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Universidade Nova de Lisboa (NOVA), and Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Fabrication, Materials science, chemistry.chemical_element, Nanotechnology, 02 engineering and technology, Nitride, 01 natural sciences, law.invention, chemistry.chemical_compound, Nanopores, FIB, law, 0103 physical sciences, Electrical and Electronic Engineering, Gallium, [PHYS.COND.CM-MSQHE]Physics [physics]/Condensed Matter [cond-mat]/Mesoscopic Systems and Quantum Hall Effect [cond-mat.mes-hall], 010302 applied physics, Graphene, Ultra-thin membranes, Dielectric films, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Atomic and Molecular Physics, and Optics, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Amorphous solid, Boron nitride, Nanopore, Membrane, chemistry, 0210 nano-technology
Abstract: International audience; Fabrication of nanopores and nanomasks has recently emerged as an area of considerable interest for research applications ranging from optics, to electronics and to biophysics. In this work we evaluate and compare the fabrication of nanopores, using a finely focused gallium beam, in free-standing membranes/films made of Si, SiN, and SiO2 (having thicknesses of a few tens of nanometers) and also in graphene and hexagonal boron nitride (h-BN) atomically thin suspended sheets. Mechanical resistance, charging effects and patterning performances are evaluated and compared. In spite of the very different properties of the membranes we report that reproducible nanopore fabrication in the sub-10 nm range can be achieved in both amorphous and atomically thin sheets using Ga+ focused ion beams (FIB).
Published: 2014
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24. The amorphous silica-liquid water interface studied by ab initio molecular dynamics (AIMD): local organization in global disorder

Author: Dominique Costa, Marialore Sulpizi, Alvaro Cimas, Frederik Tielens, Marie-Pierre Gaigeot, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Chimie de la Matière Condensée de Paris (site Paris VI) (LCMCP (site Paris VI)), Université Pierre et Marie Curie - Paris 6 (UPMC)-Collège de France (CdF)-Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS), Johannes Gutenberg - University of Mainz (JGU), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Institut de Recherche de Chimie Paris (IRCP), Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), GENCI at IDRIS [c2013082217], CINES supercomputer centers in France, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Collège de France (CdF (institution))-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Johannes Gutenberg - Universität Mainz (JGU), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), Chemistry, Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU)
Subjects: Models, Molecular, Proton, Surface Properties, amorphous silica, water, geminal silanols, 02 engineering and technology, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, Ab initio molecular dynamics, Computational chemistry, Molecule, General Materials Science, Quartz, Geminal, Molecular Structure, Chemistry, ab initio molecular dynamics, Hydrogen Bonding, [CHIM.MATE]Chemical Sciences/Material chemistry, Silanes, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Silicon Dioxide, 0104 chemical sciences, Amorphous solid, Chemical physics, Quantum Theory, Amorphous silica, Protons, 0210 nano-technology, Vicinal
Abstract: International audience; The structural organization of water at a model of amorphous silica-liquid water interface is investigated by ab initio molecular dynamics (AIMD) simulations at room temperature. The amorphous surface is constructed with isolated, H-bonded vicinal and geminal silanols. In the absence of water, the silanols have orientations that depend on the local surface topology (i.e. presence of concave and convex zones). However, in the presence of liquid water, only the strong inter-silanol H-bonds are maintained, whereas the weaker ones are replaced by H-bonds formed with interfacial water molecules. All silanols are found to act as H- bond donors to water. The vicinal silanols are simultaneously found to be H- bond acceptors from water. The geminal pairs are also characterized by the formation of water H- bonded rings, which could provide special pathways for proton transfer(s) at the interface. The first water layer above the surface is overall rather disordered, with three main domains of orientations of the water molecules. We discuss the similarities and differences in the structural organization of the interfacial water layer at the surface of the amorphous silica and at the surface of the crystalline (0001) quartz surface.
Published: 2014
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25. Protein Unfolding Through Nanopores

Author: Juan Pelta, Abdelghani Oukhaled, Loïc Auvray, Jérôme Mathé, Laurent Bacri, Manuela Pastoriza-Gallego, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire Matériaux Polymères aux Interfaces (MPI), Université d'Évry-Val-d'Essonne (UEVE), Matière et Systèmes Complexes (MSC (UMR_7057)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Bacri, Laurent, and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Models, Molecular, Protein Denaturation, Protein Conformation, Biophysics, Ionic bonding, Translocation, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Biochemistry, Nanopores, Protein structure, Structural Biology, Electric field, Molecule, Animals, Humans, Denaturation (biochemistry), ComputingMilieux_MISCELLANEOUS, Protein Unfolding, Chemistry, Protein Stability, Single-molecule technique, Proteins, General Medicine, 021001 nanoscience & nanotechnology, 0104 chemical sciences, [PHYS.COND.CM-SCM] Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], Crystallography, Nanopore, Electric detection, Unfolded protein response, Protein folding, 0210 nano-technology, [PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft]
Abstract: International audience; In this mini-review we introduce and discuss a new method, at single molecule level, to study the protein fold-ing and protein stability, with a nanopore coupled to an electric detection. Proteins unfolded or partially folded passing through one channel submitted to an electric field, in the presence of salt solution, induce different detectable blockades of ionic current. Their duration depends on protein conformation. For different studies proteins through nanopores, com-pletely unfolded proteins induce only short current blockades. Their frequency increases as the concentration of denatur-ing agent or temperature increases, following a sigmoidal denaturation curve. The geometry or the net charge of the nanopores does not alter the unfolding transition, sigmoidal unfolding curve and half denaturing concentration or half temperature denaturation. A destabilized protein induces a shift of the unfolding curve towards the lower values of the de-naturant agent compared to the wild type protein.Partially folded proteins exhibit very long blockades in nanopores. The blockade duration decreases when the concentration of denaturing agent increases. The variation of these blockades could be associated to a possible glassy behaviour.
Published: 2014

26. Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection

Author: Cristine Gonçalves, Marie-Pierre Gosselin, Hervé Cheradame, Philippe Guégan, Mathieu Berchel, Virginie Malard, Paul-Alain Jaffrès, Patrick Midoux, Chantal Pichon, Centre de biophysique moléculaire (CBM), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Chimie, Electrochimie Moléculaires et Chimie Analytique (CEMCA), Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Chimie des polymères (LCP), Institut Parisien de Chimie Moléculaire (IPCM), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut Parisien de Chimie Moléculaire (IPCM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université de Brest (UBO)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Polymers, [SDV]Life Sciences [q-bio], Green Fluorescent Proteins, Melanoma, Experimental, Pharmaceutical Science, 02 engineering and technology, Transfection, 03 medical and health sciences, RNA interference, Cell Line, Tumor, Humans, Polyethyleneimine, Gene silencing, Luciferase, Cationic liposome, Histidine, RNA, Messenger, RNA, Small Interfering, Luciferases, Cytotoxicity, Polymer, 030304 developmental biology, 0303 health sciences, Liposome, Chemistry, Imidazoles, Phosphoramidate, 021001 nanoscience & nanotechnology, Biochemistry, Liposomes, RNA, 0210 nano-technology, HeLa Cells
Abstract: International audience; Lipopolyplexes formulations resulting from association of nucleic acid, cationic liposomes and a cationic polymer are attracting formulations for siRNA delivery. Herein, imidazole- and imidazolium-based liposomes in association with histidinylated polymers are studied to produce siRNA lipopoplyplexes (LPRi) subsequently used for gene silencing. Several kinds of imidazole/histidine liposomes and cationic polymers are tested. The gene silencing effect is evaluated with synthetic siRNA directed against EGFP or luciferase mRNA, in HeLa cells stably expressing EGFP or B16F10 melanoma cells stably expressing luciferase, respectively. SiRNA formulations are compared with those prepared using some commercial transfection reagents. One formulation called His-lPEI LPRi100 comprising siRNA, histidinylated lPEI (His-lPEI) and liposomes 100 made with O,O-dioleyl-N-[3N-(N-methylimidazolium iodide)propylene] phosphoramidate and O,O-dioleyl-N-histamine phosphoramidate appears to give the best specific inhibition of gene expression at 10 nM siRNA in a dose-dependent manner with low cytotoxicity. This formulation exhibits a size and a zeta potential of 60 nm and +84 mV, respectively. According to our previous works, histidinylated lipopolyplexes appears as a versatile formulation for DNA, mRNA and siRNA transfection.
Published: 2014
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27. The unique photophysical properties of the Peridinin-Chlorophyll-a-Protein

Author: Riccardo Spezia, Marilena Di Valentin, Donatella Carbonera, Alberto Mezzetti, Dipartimento di Scienze Chimiche [Padova], Università degli Studi di Padova = University of Padua (Unipd), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement - UMR 8516 (LASIRE), Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Service de Bioénergétique, Biologie Stucturale, et Mécanismes (SB2SM), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Universita degli Studi di Padova, Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Centrale Lille Institut (CLIL), Dipartimento di Scienze Chimiche, Universita degli Studi di Padova = University of Padua = Université de Padoue, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement ( LAMBE - UMR 8587 ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université de Cergy Pontoise ( UCP ), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne ( UEVE ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Spectrochimie Infrarouge et Raman - UMR 8516 ( LASIR ), Université de Lille-Centre National de la Recherche Scientifique ( CNRS ), Service de Bioénergétique, Biologie Stucturale, et Mécanismes ( SB2SM ), Centre National de la Recherche Scientifique ( CNRS ) -Institut de Biologie Intégrative de la Cellule ( I2BC ), and Université Paris-Sud - Paris 11 ( UP11 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ) -Université Paris-Sud - Paris 11 ( UP11 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS )
Subjects: Energy transfer, Protozoan Proteins, Nanotechnology, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, peridinin-chlorophyll-protein, chemistry.chemical_compound, Molecular Biology, Chemistry, photoprotection, Cell Biology, General Medicine, Photochemical Processes, 021001 nanoscience & nanotechnology, light-harvesting, Carotenoids, 0104 chemical sciences, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Peridinin, [ CHIM.THEO ] Chemical Sciences/Theoretical and/or physical chemistry, Dinoflagellida, peridinin, 0210 nano-technology
Abstract: Peridinin-Chlorophyll-a-Proteins (PCPs) are water-soluble light harvesting complexes from dinoflagellates. They have unique light-harvesting and energy transfer properties which have been studied in details in the last 15 years. This review aims to give an overview on all the main aspects of PCPs photophysics, with an emphasis on some aspects which have not been reviewed in details so far, such as vibrational spectroscopy studies, theoretical calculations, and magnetic resonance studies. A paragraph on the present development of PCPs towards technological applications is also included.
Published: 2014
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28. Novel aliphatic polyesters from an oleic acid based monomer. Synthesis, epoxidation, cross-linking and biodegradation

Author: Fabrice Laflèche, Yann Raoul, Nathalie Jarroux, Philippe Guégan, Sylvain Claude, Pierre-Jean Roumanet, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), ONIDOL, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Organisation Nationale Interprofessionnelle des Graines et Fruits Oléagineux (ONIDOL), Unité de Nutrition Humaine - Clermont Auvergne (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne (UCA), Institut Parisien de Chimie Moléculaire (IPCM), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Renewable resources, Condensation polymer, Materials science, Polymers and Plastics, [SDV]Life Sciences [q-bio], Diol, General Physics and Astronomy, Epoxide, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, chemistry.chemical_compound, Polymer chemistry, Materials Chemistry, Organic chemistry, Poly(ester), chemistry.chemical_classification, Organic Chemistry, Fatty acids derivatives, Polymer, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Polyester, Oleic acid, Monomer, chemistry, Polymerization, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], 0210 nano-technology
Abstract: The synthesis of polymeric materials based on monomers from renewable feedstocks is a steadily growing field. New aliphatic polyesters derived from the 1,18-(Z)-octadec-9-enedioic acid (D18:1), a high oleic sunflower oil fatty acid derivative, and aliphatic diols of different molecular weight (from 1,3-propanediol to 1,12-dodecanediol) have been synthesized and characterized. The polymerization was undertaken by direct bulk polycondensation of a diacid with a diol, with or without a metal catalyst, leading to viscous liquid to solid semi-crystalline polyesters at room temperature, depending on the diol type. The molecular weights of polyesters ranged between 7000 and 20,000 g mol −1 . The main attractive aspects of these polyesters are the renewable biomass origin of the diacid and the presence of double bonds on the polymer backbone (oleic acid derivative) allowing subsequent chemical modifications. The epoxidation of these double bonds was undertaken on the macromolecular chains to induce the photochemical cross-linking of the epoxide functions. Transparent and homogeneous cross-linked films were made by photo-polymerization of the epoxy units with less than 5% of extractible products. Enzymatic degradation of these polyesters (cross-linked) was poor over 8 weeks.
Published: 2013
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29. Trace lead analysis based on carbon-screen-printed-electrodes modified via 4-carboxy-phenyl diazonium salt electroreduction

Author: Nizar Bellakhal, Stéphane Dorbes, Sarra Bouden, Annie Chaussé, Christine Vautrin-Ul, Omar El Tall, Mohamed Dachraoui, Interfaces, Traitements, Organisation et Dynamique des Systèmes (ITODYS (UMR_7086)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de chimie de coordination (LCC), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie de Toulouse (ICT-FR 2599), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut National des Sciences Appliquées et de Technologie [Tunis] (INSAT), Laboratoire de Chimie Analytique et Electrochimie, Faculté des Sciences de Tunis, Interfaces, Confinement, Matériaux et Nanostructures ( ICMN), Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université de Tunis El Manar (UTM), Centre de Recherche sur la Matière Divisée (CRMD), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Centre de recherche sur la matière divisée (CRMD), and Université d'Orléans (UO)
Subjects: Trace Amounts, Square wave voltammetry, 02 engineering and technology, Electrochemistry, 01 natural sciences, Analytical Chemistry, Adsorptive stripping voltammetry, Chronoamperometry, Limit of Detection, electrochemical analysis, Environmental analysis, Chemistry, [SDE.IE]Environmental Sciences/Environmental Engineering, pH, article, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Electrode, pollutant, Environmental Pollutants, 0210 nano-technology, Lead detection, Limit of quantifications, Oxidation-Reduction, Anodic oxidation, Inorganic chemistry, Chemical detection, Electrochemical reductions, chemistry, Adsorption, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Humans, Zinc compounds, human, Screen-printed carbon electrodes, Electrodes, Reduction, Detection limit, Manganese, lead, Electrolytic reduction, 010401 analytical chemistry, Trace analysis, Diazonium Compounds, Electrochemical Techniques, electrode, Carbon, 0104 chemical sciences, Electrochemical electrodes, Surface coating, Screen printed electrodes, Carbon screen-printed electrode, Voltammetry, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], diazonium compound, oxidation reduction reaction
Abstract: International audience; This paper describes the use of 4-carboxyphenyl-grafted screen-printed carbon electrodes (4-CP-SPEs) for trace lead analysis. These novel and simple use of electrodes were easily prepared by the electrochemical reduction of the corresponding diazonium salt. Pb detection was then performed by a three-steps method in order to avoid oxygen interference: (i) immersion of the grafted screen-printed electrode (SPE) in the sample and adsorption of Pb(II), (ii) reduction of adsorbed Pb(II) by chronoamperometry (CA), and (iii) oxidation of Pb by Anodic Square Wave Voltammetry (SWV). The reoxidation response was exploited for lead detection and quantification. In order to optimize the analytical responses, the influence of the adsorption medium pH and the adsorption time were investigated. Moreover, an interference study was carried out with Cu(II), Hg(II), Al(III), Mn(II), Zn(II), Cd(II) and no major interference can be expected to quantify Pb(II). The described method provided a limit of detection and a limit of quantification of 1.2 × 10-9 M and 4.1 × 10-9 M, respectively. These performances indicate that the 4-CP-SPE could be considered as an efficient tool for environmental analysis.
Published: 2013
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30. Influence of the Pairwise Potential on the Tangential Momentum Accommodation Coefficient: a Multi-Scale Study applied to the Argon on Pt(111) System

Author: Vincent Brites, Guy Lauriat, Thanh Tung Pham, Céline Léonard, Quy-Dong To, Laboratoire de Modélisation et Simulation Multi Echelle (MSME), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Paris-Est Marne-la-Vallée (UPEM), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Est Marne-la-Vallée (UPEM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), and Université Paris-Seine-Université Paris-Seine
Subjects: Surface (mathematics), Physics, Argon, Solid-state physics, Scale (ratio), Computation, chemistry.chemical_element, 02 engineering and technology, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, Molecular physics, Electronic, Optical and Magnetic Materials, Momentum, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Molecular dynamics, chemistry, 0103 physical sciences, Pairwise comparison, Atomic physics, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, 010306 general physics, 0210 nano-technology
Abstract: International audience; The tangential momentum accommodation coefficient (TMAC) of argon atoms on a Pt(111) surface has been investigated using a multi-scale computational approach in order to emphasize the effect of the Pt-Ar pairwise potential on this parameter. For the different Pt-Ar pairwise potentials available in the literature, the TMAC has been determined by Molecular Dynamics simulations from the difference of the incident and reflected velocities of projected Ar atoms on the atomistic Pt surface. Temperature and incident angle dependencies of this parameter are also explored. A new Pt-Ar potential has also been calculated using periodic density functional theory computations. The resulting potential successfully reproduced the available experimental data and is compared with the previous empirical potentials. The TMAC deduced from our pairwise potential is 0.42 at T = 300 K.
Published: 2013
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31. DNA Unzipping and Protein Unfolding Using Nanopores

Author: Loïc Auvray, Abdelghani Oukhaled, Céline Merstorf, Juan Pelta, Jérôme Mathé, Manuela Pastoriza-Gallego, Jacques Gierak, Laurent Bacri, Benjamin Cressiot, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de photonique et de nanostructures (LPN), Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Matériaux Polymères aux Interfaces (MPI), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Bacri, Laurent, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC (UMR_7057)), Université d'Évry-Val-d'Essonne (UEVE), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)
Subjects: 0303 health sciences, Materials science, Orders of magnitude (temperature), 02 engineering and technology, 021001 nanoscience & nanotechnology, [PHYS.COND.CM-SCM] Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], 03 medical and health sciences, Nanopore, chemistry.chemical_compound, chemistry, Chemical physics, Unfolded protein response, 0210 nano-technology, [PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], DNA, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology
Abstract: We present here an overview on unfolding of biomolecular structures as DNA double strands or protein folds. After some theoretical considerations giving orders of magnitude about transport timescales through pores, forces involved in unzipping processes … we present our experiments on DNA unzipping or protein unfolding using a nanopore. We point out the difficulties that can be encountered during these experiments, such as the signal analysis problems, noise issues, or experimental limitations of such system.
Published: 2012

32. Transport of Long Neutral Polymers in the Semidilute Regime through a Protein Nanopore

Author: Juan Pelta, Anne-Laure Biance, Laurent Bacri, Loïc Auvray, Abdelghani Oukhaled, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique de la Matière Condensée et Nanostructures (LPMCN), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Matière et Systèmes Complexes (MSC (UMR_7057)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)
Subjects: Materials science, Polymers, PACS: 82.35.Pq, 87.16.dp, 36.20.Ey, Lipid Bilayers, General Physics and Astronomy, Nanotechnology, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, chemistry.chemical_compound, Hemolysin Proteins, Nanopores, chemistry.chemical_classification, Molecular mass, Biological Transport, Polymer, Radius, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Molecular Weight, Dwell time, Nanopore, Reptation, Monomer, [CHIM.POLY]Chemical Sciences/Polymers, chemistry, Chemical physics, 0210 nano-technology, Ethylene glycol, [PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft]
Abstract: We investigate the entrance of single poly(ethylene glycol) chains into an $\ensuremath{\alpha}$-hemolysin channel. We detect the frequency and duration of the current blockades induced by large neutral polymers, where chain radius is larger than pore diameter. In the semidilute regime, these chains pass only if the monomer concentration is larger than a well-defined threshold. Experiments are performed in a very large domain of concentration and molecular mass, up to $35%$ and 200 kDa, respectively, which was previously unexplored. The variation of the dwell time as a function of molecular mass shows that the chains are extracted from the semidilute solution in contact with the pore by a reptation mechanism.
Published: 2012
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33. Dynamics of Completely Unfolded and Native Proteins through Solid-State Nanopores as a Function of Electric Driving Force

Author: E. Bourhis, Laurent Bacri, Jacques Gierak, Benjamin Cressiot, Juan Pelta, Ralf Jede, Loïc Auvray, Jean-Michel Betton, Abdelghani Oukhaled, Manuela Pastoriza-Gallego, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de photonique et de nanostructures (LPN), Centre National de la Recherche Scientifique (CNRS), Biochimie Structurale, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], RAITH GmbH, Matière et Systèmes Complexes (MSC (UMR_7057)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), ANR-08-BLAN-0094,TRANSFOLDPROT,Dynamics and mechanics of protein transport, interaction and folding through different protein channels at the single molecule level(2008), ANR-06-NANO-0028,ACTIVE NANOPORES,Fluorescently or chemically active solid state nanopores made by focused ions beam for the detection or synthesis of passing macromolecules(2006), ANR-08-NSCI-0006,Nanopore(2008), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), and ANR-08-NSCI-0006,Nanopore,Novel force spectroscopy with nanopores(2008)
Subjects: Electric fields, [PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], General Physics and Astronomy, 02 engineering and technology, Radiation Dosage, 010402 general chemistry, Biological transpor, 01 natural sciences, Nanopores, Electromagnetic Fields, Computer Simulation, General Materials Science, Conformation, Protein Unfolding, Membrane potential, Chemistry, General Engineering, Proteins, 021001 nanoscience & nanotechnology, Nanostructures, 0104 chemical sciences, Exponential function, Transport protein, Crystallography, Nanopore, Electroporation, Electrical transport, Models, Chemical, Chemical physics, Unfolded protein response, Stress, Mechanical, 0210 nano-technology, Porosity, Order of magnitude, Protein adsorption, Voltage
Abstract: International audience; We report experimentally the dynamic properties of the entry and transport of unfolded and native proteins through a solid-state nanopore as a function of applied voltage, and we discuss the experimental data obtained as compared to theory. We show an exponential increase in the event frequency of current blockades and an exponential decrease in transport times as a function of the electric driving force. The normalized current blockage ratio remains constant or decreases for folded or unfolded proteins, respectively, as a function of the transmembrane potential. The unfolded protein is stretched under the electric driving force. The dwell time of native compact proteins in the pore is almost 1 order of magnitude longer than that of unfolded proteins, and the event frequency for both protein conformations is low. We discuss the possible phenomena hindering the transport of proteins through the pores, which could explain these anomalous dynamics, in particular, electro-osmotic counterflow and protein adsorption on the nanopore wall.
Published: 2011
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34. Chemical and Physicochemical Investigation of an Aminoalkylalkoxysilane As Strengthening Agent for Cellulosic Materials

Author: Zied Souguir, Bertrand Lavédrine, Jean-Baptiste d'Espinose de Lacaillerie, Anne-Laurence Dupont, Hervé Cheradame, Centre de Recherche pour la Conservation des Collections (CRCC), Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physico-Chimie des Polymères et des Milieux Dispersés (PPMD), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-ESPCI ParisTech-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Paper, Magnetic Resonance Spectroscopy, Polymers and Plastics, Alkylation, Sodium Hypochlorite, Surface Properties, Nanofibers, Bioengineering, 02 engineering and technology, Degree of polymerization, Alkalies, 010402 general chemistry, 01 natural sciences, Polymerization, Biomaterials, chemistry.chemical_compound, symbols.namesake, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Materials Chemistry, medicine, Organic chemistry, Library Materials, Reactivity (chemistry), Fiber, Cellulose, Amines, aminopropylmethyldiethoxysilane, Chemistry, Hydrolysis, [CHIM.MATE]Chemical Sciences/Material chemistry, Silanes, 021001 nanoscience & nanotechnology, eye diseases, 0104 chemical sciences, Maillard reaction, [CHIM.POLY]Chemical Sciences/Polymers, Sodium hypochlorite, symbols, Strengthening, Swelling, medicine.symptom, 0210 nano-technology, Oxidation-Reduction
Abstract: International audience; AMDES (aminopropylmethyldiethoxysilane) was used to investigate the physicochemical and chemical events related to the introduction of aminoalkylalkoxysilanes in cellulosic materials. Using 29Si CP-MAS and 1H NMR to study the reactivity and structural modification of AMDES in the paper it was shown that polymerization occurs in situ. The distribution of the active compound on the surface of the fibers and throughout the fibers’ thickness was visualized by SEM-EDS. A relation between moisture content, fiber swelling, and uptake of AMDES was found. To better represent old and brittle documents, the paper was predegraded by oxidation with sodium hypochlorite. XRD confirmed the advanced destruction of the amorphous areas of cellulose. Adding AMDES in the oxidized paper resulted in improved mechanical properties, a roughly unmodified degree of polymerization of cellulose, but a slight increase in the yellowing, probably due to several possible reaction products such as imines, amine, amides, and Maillard reactions products. The deacidification efficacy was established and the strengthening effect was shown to arise from the interaction of AMDES with the cellulose fibers.
Published: 2011
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35. Dynamics of Colloids in Single Solid-State Nanopores

Author: E. Bourhis, Juan Pelta, B. Schiedt, Abdelghani Oukhaled, Jacques Gierak, Gilles Patriarche, Laurent Bacri, Loïc Auvray, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de photonique et de nanostructures (LPN), Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC (UMR_7057)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Matière et Systèmes Complexes (MSC), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)
Subjects: Materials science, Nanoparticle, Ionic bonding, High voltage, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, [INFO.INFO-SI]Computer Science [cs]/Social and Information Networks [cs.SI], 0104 chemical sciences, Surfaces, Coatings and Films, Electrophoresis, Colloid, Nanopore, Nanopores, Colloidal particles, Chemical physics, Materials Chemistry, Electrical properties, Nanoparticles, Colloids, Physical and Theoretical Chemistry, Current (fluid), 0210 nano-technology, Voltage
Abstract: International audience; We use solid-state nanopores to study the dynamics of single electrically charged colloids through nanopores as a function of applied voltage. We show that the presence of a single colloid inside of the pore changes the pore resistance, in agreement with theory. The normalized ionic current blockade increases with the applied voltage and remains constant when the electrical force increases even more. We observe short and long events of current blockades. Their durations are associated, respectively, with low and high current variation. The ratio of long events increases with the electrical force. The events frequency increases exponentially as a function of applied voltage and saturates at high voltage. The dwelling time decreases exponentially at low and medium voltages when the electrical force increases. At large voltages, this time decreases inversely proportionally to the applied voltage. The long events are associated with translocation events. We show that the dynamics of colloids through the nanopore is governed mainly by two mechanisms, by the free-energy barrier at relatively low and medium voltages and by the electrophoresis mechanism at high voltage.
Published: 2011
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36. Estimating the stabilities of actinide aqueous species. Influence of sulfoxy-anions on uranium(IV) geochemistry and discussion of Pa(V) first hydrolysis

Author: Pierre Vitorge, Jean-Paul Gaudet, Thomas Vercouter, Catherine Beaucaire, Vannapha Phrommavanh, Bertrand Siboulet, Dominique You, Colin J. Marsden, Michael Descostes, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay-Université d'Évry-Val-d'Essonne (UEVE)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine, Laboratoire de Spéciation des Radionucléides et des Molécules (LSRM), Département de Physico-Chimie (DPC), CEA-Direction de l'Energie Nucléaire (CEA-DEN), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-CEA-Direction de l'Energie Nucléaire (CEA-DEN), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Mesures et Modélisation de la Migration des Radionucléides (L3MR), Service d'Etudes du Comportement des Radionucléides (SECR), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Département de Physico-Chimie (DPC), Service de Chimie des Procédés de Séparation (SCPS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Chimie des éléments d & f (LCPQ), Laboratoire de Chimie et Physique Quantiques (LCPQ), Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'étude des transferts en hydrologie et environnement (LTHE), Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique de Grenoble (INPG)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), and Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Carbonate, Thiosulphate, General Chemical Engineering, Inorganic chemistry, Analytical chemistry, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Chemical reaction, Actinides, Compounds of carbon, Equilibrium constant, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, Aqueous solution, Chemistry, Hydrolysis, General Chemistry, Actinide, Sulphate, 021001 nanoscience & nanotechnology, Decomposition, 0104 chemical sciences, Groundwaters, 13. Climate action, Sulfite, Solvolysis, 0210 nano-technology, [CHIM.CHEM]Chemical Sciences/Cheminformatics, Waste disposal
Abstract: Qualitative chemical information is used as a guideline for correlations between equilibrium constants or between equilibrium constants and atomic charges (deduced from quantum mechanics calculations). Pa(V) and Nb(V) hydrolysis constants are also recalculated from experimental data. log K 1 ° ( A n IV / R O 2 2 − ) = 6.5 9 ± 0.5 5 ( S 2 O 3 2 − ) , 10.0 6 ± 0.8 8 ( S O 3 2 − ) , 11.9 7 ± 1.0 7 ( C O 3 2 − ) , and 10.0 5 ± 0.8 8 ( HP O 4 2 − ) are estimated based on the trend of affinity for An cations in the series C O 3 2 − > HP O 4 2 − ≈ S O 3 2 − > S O 4 2 − ≈ S 2 O 3 2 − . These ideas and values are used to discuss U(IV) chemistry in S-containing ground-waters.
Published: 2007
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37. Reactivity of uranium in geopolymers, confinement matrices proposed to encapsulate MgZr waste

Author: Davide Rodrigues, Sylvie Delpech, Céline Cannes, D. Lambertin, Nicole Barré, Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Service des Procedés de Décontamination et d'Enrobage des Déchets (SPDE), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)
Subjects: Nuclear and High Energy Physics, Inorganic chemistry, chemistry.chemical_element, 02 engineering and technology, 01 natural sciences, 010305 fluids & plasmas, Corrosion, Ion, chemistry.chemical_compound, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, 0103 physical sciences, [CHIM]Chemical Sciences, General Materials Science, Reactivity (chemistry), ComputingMilieux_MISCELLANEOUS, Aqueous solution, Chemistry, [CHIM.MATE]Chemical Sciences/Material chemistry, Uranium, 021001 nanoscience & nanotechnology, Geopolymer, Nuclear Energy and Engineering, Hydroxide, 0210 nano-technology, [CHIM.RADIO]Chemical Sciences/Radiochemistry, Fluoride
Abstract: The U reactivity has been examined in three geopolymer (GP) formulations: GP, GP containing 1.25 M of NaF (GP-NaF) and GP containing 1.25 M of NaF and a double concentration of NaOH (GP-NaF-NaOH). In a previous study, two mechanisms representative of uranium oxidation in basic aqueous solutions have been proposed, depending on the ratio of the fluoride and hydroxide ions concentrations (RF/OH). For RF/OH 1, U is continuously corroded (mechanism B). We have exploited the results on the GP pH evolution to understand the uranium behavior in geopolymers. With NaF at the saturated concentration in the geopolymers, if pH > 13.8, RF/OH is lower than 1, while for pH
Published: 2019
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38. Interactions of aggregating peptides probed by IR-UV action spectroscopy

Author: Anouk M. Rijs, Mart Greuell, Sjors Bakels, Eline M Meijer, Jérôme Mahé, Marie-Pierre Gaigeot, Sebastiaan B. A. Porskamp, George Rouwhorst, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), and Radboud University, Institute for Molecules and Materials, FELIX Laboratory
Subjects: Spectrophotometry, Infrared, Dimer, Peptide, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Protein Aggregates, chemistry.chemical_compound, Molecule, Physical and Theoretical Chemistry, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, Molecular Structure, Hydrogen bond, Intermolecular force, Hydrogen Bonding, Chromophore, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Crystallography, Monomer, chemistry, Intramolecular force, Quantum Theory, Spectrophotometry, Ultraviolet, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], Peptides, 0210 nano-technology
Abstract: Peptide aggregation, the self-assembly of peptides into structured beta-sheet fibril structures, is driven by a combination of intra- and intermolecular interactions. Here, the interplay between intramolecular and formed inter-sheet hydrogen bonds and the effect of dispersion interactions on the formation of neutral, isolated, peptide dimers is studied by infrared action spectroscopy. Therefore, four different homo- and hetereogeneous dimers formed from three different alanine-based model peptides have been studied under controlled and isolated conditions. The peptides differ from one another in the presence and location of a UV chromophore containing cap on either the C- or N-terminus. Conformations of the monomers of the peptides direct the final dimer structure: strongly hydrogen bonded or folded structures result in weakly bound dimers. Here the intramolecular hydrogen bonds are favored over new intermolecular hydrogen bond interactions. In contrast, linearly folded monomers are the ideal template to form parallel beta-sheet type structures. The weak intramolecular hydrogen bonds present in the linear monomers are replaced by the stronger inter-sheet hydrogen bond interactions. The influence of π-π disperion interactions on the structure of the dimer is minimal, the phenyl rings have the tendency to fold away from the peptide backbone to favour intermolecular hydrogen bond interactions. Quantum chemical calculations confirm our experimental observations.
Published: 2019
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39. Infrared-Assisted Synthesis of Prebiotic Glycine

Author: Ariel Pérez-Mellor, Jean-Xavier Bardaud, Debora Scuderi, Suvasthika Indrajith, Riccardo Spezia, Yannick Jeanvoine, Antonio Largo, Joël Lemaire, Institut de Chimie Physique (ICP), Institut de Chimie du CNRS (INC)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ecole Normale Supérieure Paris-Saclay (ENS Paris Saclay), Universidad de Valladolid [Valladolid] (UVa), Laboratoire Analyse, Modélisation et Matériaux pour la Biologie et l'Environnement (LAMBE - UMR 8587), Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Laboratoire de chimie théorique (LCT), and Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)
Subjects: IR-assisted synthesis, prebiotic chemistry, Infrared, complex organic molecules, 02 engineering and technology, 010402 general chemistry, Photochemistry, Mass spectrometry, 01 natural sciences, Acetic acid, chemistry.chemical_compound, ion-molecule reactions, Hydroxylamine, Fragmentation (mass spectrometry), Irradiation, Physical and Theoretical Chemistry, 021001 nanoscience & nanotechnology, Atomic and Molecular Physics, and Optics, 3. Good health, 0104 chemical sciences, Moléculas orgánicas complejas, chemistry, Molecular vibration, Glycine, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], 0210 nano-technology, glycine
Abstract: Producción Científica, A novel approach has been developed to synthesize complex organic molecules (COMs) relevant to prebiotic chemistry, using infrared (IR) radiation to trigger the reaction. An original laboratory reactor working at low gas density and using IR irradiation was developed. In this way, glycine, the simplest brick of life, has been synthesized by assisting ion–molecule reaction with IR laser light. The ion‐molecule complex constituted by acetic acid and hydroxylamine was formed in a mass spectrometer reactor and then irradiated with IR photons. As photoproducts, we obtained both glycine structures and some of its isomers. Anharmonic vibrational frequency calculations and fragmentation dynamics simulations allow for a better interpretation of the experimental data. This novel approach can be now extended to study other new synthetic pathways responsible for the formation of further COMs also with potential prebiotic relevance., ANR DynBioReact. Grant Number: ANR-14-CE06-0029-01, CNRS program INFINITI (project ASTROCOL). Grant Number: 2013-0562-T, Chiraux IRUV (RTRA), Labex Palm, Paris Scalay
Published: 2020
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40. Characterization of home-made graphite/PDMS microband electrodes for amperometric detection in an original reusable glass-NOA®-PDMS electrophoretic microdevice

Author: Fethi Bedioui, Jérémie Gouyon, Anne Varenne, Fanny d’Orlyé, Sophie Griveau, Institute of Chemistry for Life and Health Sciences (iCLeHS), Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS), Agence de l'Environnement et de la Maîtrise de l'Energie (ADEME), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE - UMR 8587), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Unité de pharmacologie chimique et génétique et d'imagerie (UPCGI - UMR 8151 / UMR_S 1022 ), Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Electrochimie et de Chimie Analytique (LECA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Nationale Supérieure de Chimie de Paris- Chimie ParisTech-PSL (ENSCP)-Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Synthèse, électrochimie, imagerie et systèmes analytiques pour le Diagnostic (SEISAD), Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS - UM 4 (UMR 8258 / U1022)), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), and GRIVEAU, SOPHIE
Subjects: Electrophoresis, [CHIM.ANAL] Chemical Sciences/Analytical chemistry, Materials science, General Chemical Engineering, Microfluidics, Microchip, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, chemistry.chemical_compound, Chronoamperometry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Electrochemistry, Screen printing, Polydimethylsiloxane, 021001 nanoscience & nanotechnology, Amperometry, 0104 chemical sciences, Microelectrode, chemistry, Chemical engineering, Electrode, Cyclic voltammetry, 0210 nano-technology
Abstract: International audience; A new dismountable and reusable microchip for electrophoretic separation coupled to amperometric detection was developed. For this purpose, a new home made three-microbands electrode system was developed and microfabricated based on screen-printing for the inclusion of graphite/polydimethylsiloxane (C-PDMS) composite in microchannels down to 30 μm width. The composition of the composite as well as the fabrication methodology were optimized for an easy handling and an optimized electrochemical behavior. The electrochemical characterization of this composite material was first performed in bulk format (disc-shaped electrode, 6 mm diameter). It was then transposed to the micrometric scale for its integration in an original glass-NOA81®-PDMS microfluidic device allowing for reversible sealing. The microband electrodes were characterized by scanning electron microcopy and cyclic voltammetry, illustrating a good control of the microelectrode width. Then, the analytical performances of the C-PDMS composite microelectrodes were evaluated using Ru(NH3)63+ and FcMeOH as model electroactive molecules. The electrophoretic separation and quantitation of Ru(NH3)63+ were then performed in a background electrolyte made of hydrochloric acid and sodium chloride, leading to a LOD and a LOQ of 3.4 μmol L−1 and 11.3 μmol L−1, respectively. The re-openable NOA-based microdevice permits to regenerate the electrode surface by simply repositioning the microband on a new spot, allowing for robust analysis in a reusable system.
Published: 2020
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41. Mechanical Anisotropy in GNNQQNY Amyloid Crystals

Author: Eric C. Wong, Guillaume Lamour, Roy Nassar, Hongbin Li, Calvin K. Yip, Jörg Gsponer, Jennifer M. Bui, University of British Columbia (UBC), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE)
Subjects: Steered molecular dynamics, 0301 basic medicine, Aggregates, Materials science, Amyloid, Assembly mechanism, 02 engineering and technology, Molecular dynamics, Protein aggregation, Amplitude modulation, Degrees of freedom (mechanics), Stiffness, Crystal, Atomic force microscopy, 03 medical and health sciences, Nanomechanical property, Frequency modulation, Mechanisms, medicine, General Materials Science, Physical and Theoretical Chemistry, Anisotropy, Glycoproteins, Mechanical anisotropy, Proteins, 021001 nanoscience & nanotechnology, Into-structure, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, 030104 developmental biology, Directional dependence, Crystal architecture, Structure mechanics, Biophysics, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], medicine.symptom, 0210 nano-technology, Directional variation
Abstract: International audience; Mapping the nanomechanical properties of amyloids can provide valuable insights into structure and assembly mechanisms of protein aggregates that underlie the development of various human diseases. Although it is well-known that amyloids exhibit an intrinsic stiffness comparable to that of silk (1-10 GPa), a detailed understanding of the directional dependence (anisotropy) of the stiffness of amyloids and how it relates to structural features in these protein aggregates is missing. Here we used steered molecular dynamics (SMD) simulations and amplitude modulation-frequency modulation (AM-FM) atomic force microscopy to measure the directional variation in stiffness of GNNQQNY amyloid crystals. We reveal that individual crystals display significant mechanical anisotropy and relate this anisotropy to subtle but mechanically important differences in interactions between interfaces that define the crystal architecture. Our results provide detailed insights into the structure-mechanics relationship of amyloid that may help in designing amyloid-based nanomaterials with tailored mechanical properties.
Published: 2018
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42. In situ XANES measurements during electrodeposition of thin film: Example of birnessite, a promising material for environmental applications

Author: Anne Pensel, Sophie Peulon, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE)
Subjects: In situ, Auxiliary electrode, Birnessite, Materials science, Synchrotron measurements, Thin films, General Chemical Engineering, Nanotechnology, 02 engineering and technology, 010402 general chemistry, Electrochemistry, 01 natural sciences, Electrochemical cell, Electrochemical cells, Electrodeposition, Manganese oxide, Layered manganese oxide, Counter electrodes, Electrochemical measurements, Thin film, Environmental applications, Electrodes, Real interest, Continuous flow, Oxides, Continuous flows, 021001 nanoscience & nanotechnology, XANES, 0104 chemical sciences, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], 0210 nano-technology, Large surfaces
Abstract: International audience; This paper highlights the potentialities of a very simple electrochemical set-up for studying the electrodeposition of thin film in real time by in situ XANES measurements. This study focuses on birnessite, a promising non-toxic manganese oxide for various applications. The main originality of this device comes from its window used as a counter electrode allowing the electrodeposition on large surfaces (some cm 2 ), exactly like in a classical electrochemical cell. The quality of the in situ XANES measurements is comparable to that of ex situ measurements demonstrating the real interest of this continuous flow electrochemical cell for characterising compounds during electrochemical measurements. Moreover, the electrodeposited thin films are similar to those obtained in a classical electrochemical cell, as illustrated by the ex situ characterizations (XANES, XRD and SEM). Thus, this promising set-up will allow the studies of numerous materials in the future.
Published: 2018
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43. Structural definition of the BIL and DL: a new universal methodology to rationalize non-linearχ(2)(ω) SFG signals at charged interfaces, includingχ(3)(ω) contributions

Author: Daria Ruth Galimberti, Simone Pezzotti, Y. Ron Shen, Marie-Pierre Gaigeot, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Department of Physics [Berkeley], University of California [Berkeley], University of California-University of California, University of California [Berkeley] (UC Berkeley), and University of California (UC)-University of California (UC)
Subjects: Physics, Work (thermodynamics), Sum-frequency generation, Liquid water, General Physics and Astronomy, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Interpretation (model theory), [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Nonlinear system, Third order, Normal mode, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], Physical and Theoretical Chemistry, Atomic physics, 0210 nano-technology
Abstract: International audience; This work provides unambiguous definitions from theoretical simulations of the two interfacial regions named the BIL (binding interfacial layer) and DL (diffuse layer) at charged solid/water and air/water interfaces. The BIL and DL nomenclature follows the pioneering work of Wen et al. [Phys. Rev. Lett. 2016, 116, 016101]. Our definitions are based on the intrinsic structural properties of water only. Knowing the BIL and DL interfacial regions, one is then able to deconvolve the χ(2)(ω) non-linear SFG (sum frequency generation) response into χ(2)BIL(ω) and χ(2)DL(ω) contributions, thus providing a detailed molecular interpretation of these signals and of the measured total SFG. We furthermore show that the χ(2)DL(ω) spectrum arises from the χ(3)(ω) non-linear third order contribution of bulk liquid water, here calculated for several charged interfaces and shown to be universal. The χ(2)DL(ω) contribution therefore has the same origin in terms of molecular normal modes at any charged interface. The molecular interpretation of χ(2)BIL(ω) is hence at the heart of the unambiguous molecular comprehension and interpretation of the measured total SFG signal at any charged interface.
Published: 2018
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44. Interaction of TiO2 nanoparticles with proteins from aquatic organisms: the case of gill mucus from blue mussel

Author: Serge Pin, Véronique Legros, Florence Gonnet, Aurélie Paquirissamy, Olivier Spalla, Clémence Bénatar, Régis Daniel, Jean Philippe Renault, Corinne Chanéac, Adeline Bourgeault, Laboratoire Interdisciplinaire sur l'Organisation Nanométrique et Supramoléculaire (LIONS), Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M) (NIMBE UMR 3685), Institut Rayonnement Matière de Saclay (IRAMIS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut Rayonnement Matière de Saclay (IRAMIS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Laboratoire de Chimie de la Matière Condensée de Paris (LCMCP), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Institut Rayonnement Matière de Saclay (IRAMIS), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)
Subjects: Interaction, nanoLC-MS/MS, Health, Toxicology and Mutagenesis, Protein Corona, 02 engineering and technology, 010501 environmental sciences, Tandem mass spectrometry, 01 natural sciences, chemistry.chemical_compound, Adsorption, Aromatic amino acids, Environmental Chemistry, Gill mucus, Polyacrylamide gel electrophoresis, 0105 earth and related environmental sciences, [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, Chromatography, Chemistry, Protein, 1D PAGE, technology, industry, and agriculture, General Medicine, 021001 nanoscience & nanotechnology, Pollution, Mucus, Unfolded protein response, Biophysics, Mussel, 0210 nano-technology, TiO2 nanoparticles, Protein adsorption
Abstract: International audience; To better understand the mechanisms of TiO2 nanoparticle (NP) uptake and toxicity in aquatic organisms, we investigated the interaction of NPs with the proteins found in gill mucus from blue mussels. Mucus is secreted by many aquatic organisms and is often their first line of defense against pathogens, xenobiotics, and other sources of environmental stress. Here, five TiO2 NPs and one SiO2 NP were incubated with gill mucus and run out on a one-dimensional polyacrylamide gel for a comparative qualitative analysis of the free proteins in the mucosal solution and the proteins bound to NPs. We then used nanoscale liquid chromatography coupled with tandem mass spectrometry to identify proteins of interest. Our data demonstrated dissimilar protein profiles between the crude mucosal solution and proteins adsorbed on NPs. In particular, extrapallial protein (EP), one of the most abundant mucus proteins, was absent from the adsorbed proteins. After thermal denaturation experiments, this absence was attributed to the EP content in aromatic amino acids that prevents protein unfolding and thus adsorption on the NP. Moreover, although the majority of the protein corona was qualitatively similar across the NPs tested here (SiO2 and TiO2), a few proteins in the corona showed a specific recruitment pattern according to the NP oxide (TiO2 vs SiO2) or crystal structure (anatase TiO2 vs rutile TiO2). Therefore, protein adsorption may vary with the type of NP. Graphical abstract Proteins with adsorption selectivity as identified from isolated bands.
Published: 2017
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45. Deconvolution of BIL-SFG and DL-SFG spectroscopic signals reveals order/disorder of water at the elusive aqueous silica interface

Author: Daria Ruth Galimberti, Marie-Pierre Gaigeot, Simone Pezzotti, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE)
Subjects: Aqueous solution, Materials science, Analytical chemistry, Ab initio, General Physics and Astronomy, 02 engineering and technology, Electrolyte, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Amorphous solid, Ion, Crystallinity, Molecular dynamics, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph], Physical and Theoretical Chemistry, 0210 nano-technology, Spectroscopy, ComputingMilieux_MISCELLANEOUS
Abstract: Through the prism of the rather controversial and elusive silica/water interface, ab initio DFT-based molecular dynamics simulations of the structure and non-linear SFG spectroscopy of the interface are analysed. Following our recent work [Phys. Chem. Chem. Phys., 2018, 20, 5190-5199], we show that once the interfacial water is decomposed into BIL (Binding Interfacial Layer) and DL (Diffuse Layer) interfacial regions, the SFG signals can be deconvolved and unambiguously interpreted, and a global microscopic understanding on silica/water interfaces can be obtained. By comparing crystalline quartz/water and amorphous (fused) silica/water interfaces, the dependence of interfacial structural and spectroscopic properties on the degree of surface crystallinity is established, while by adding KCl electrolytes at the quartz/water interface, the chaotropic effect of ions on the interfacial molecular arrangement is unveiled. The evolution of structure and SFG spectra of silica/water interfaces with respect to increasing surface deprotonation, i.e., with respect to pH conditions, is also evaluated. Spectroscopic BIL-SFG markers that experimentally allow one detect the water order/disorder in the BIL as a function of surface hydroxylation and ion concentration are revealed, while the pH-induced modulations in the experimentally recorded SFG spectra are rationalized in terms of changes in both BIL and DL SFG signatures.
Published: 2019
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46. Ionic transport through a protein nanopore: a Coarse-Grained Molecular Dynamics Study

Author: Delphine Dessaux, Nathalie Basdevant, Rosa Ramirez, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE)
Subjects: Materials science, [PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], Lipid Bilayers, Static Electricity, Ionic bonding, lcsh:Medicine, FOS: Physical sciences, 02 engineering and technology, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, Force field (chemistry), Article, Molecular dynamics, Computational biophysics, Hemolysin Proteins, Nanopores, Electric field, Ionic conductivity, Physics - Biological Physics, Lipid bilayer, lcsh:Science, Ions, Multidisciplinary, Ion Transport, lcsh:R, Electric Conductivity, 021001 nanoscience & nanotechnology, 3. Good health, 0104 chemical sciences, [SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Nanopore, Chemical physics, Biological Physics (physics.bio-ph), lcsh:Q, 0210 nano-technology, Biological physics, Order of magnitude
Abstract: The MARTINI coarse-grained (CG) force field is used to test the ability of CG models to simulate ionic transport through protein nanopores. The ionic conductivity of CG ions in solution was computed and compared with experimental results. Next, we studied the electrostatic behavior of a solvated CG lipid bilayer in salt solution under an external electric field. We showed this approach correctly describes the experimental conditions under a potential bias. Finally, we performed CG molecular dynamics simulations of the ionic transport through a protein nanopore ($\alpha$-hemolysin) inserted in a lipid bilayer, under different electric fields, for 2-3 microseconds. The resulting $I-V$ curve is qualitatively consistent with experiments, although the computed current is one order of magnitude smaller. Current saturation was observed for potential biases over $\pm~350$~mV. We also discuss the time to reach a stationary regime and the role of the protein flexibility in our CG simulations., Comment: 13 pages, 6 figures in the main text. 3 pages, 4 figures in the supplement
Published: 2019
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47. Films minces de birnessite électrodéposés : Un matériau éco-compatible pour éliminer des métaux lourds de l'eau

Author: R. Choumane, Sophie Peulon, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), and Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE)
Subjects: Sorbent, Materials science, Birnessite, chemistry.chemical_element, 02 engineering and technology, Wastewater treatment, 010402 general chemistry, Electrochemistry, depollution, 01 natural sciences, Colloid and Surface Chemistry, Adsorption, Electrodeposition, Desorption, Cadmium, Sorption, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, chemistry, Chemical engineering, Heavy metals, 13. Climate action, Ionic strength, Layered manganese oxides, 0210 nano-technology, Phyllomanganate
Abstract: International audience; Sorption is an efficient process for transferring heavy metals from polluted water to solid phase. Birnessite, which is a non-toxic layered manganese oxide, is particularly interesting for this objective due to its high sorption capacities towards heavy metals. In this paper, pure and nanostructured birnessite was synthesized as adherent thin films onto a solid substrate by electrochemistry with different characteristics for high sorption (e.g. mass, Average Oxidation States of Mn (AOS)). Sorption of lead (Pb (II)) and cadmium (Cd (II)) by these films was studied in terms of pH, ionic strength, sorption isotherm and kinetic order. The birnessite thin film with the highest AOS after synthesis (3.76) presents significant adsorption capacity for Pb (II) (538 mg-Pb/g) and Cd (II) (254 mg-Cd/g). A total decontamination at room temperature without filtration and energy input was obtained on model solutions and real effluents by increasing only the number of samples or the surface of electrodeposited birnessite on one sample. These birnessite thin films appear as very interesting eco-friendly sorbents for eliminating Pb (II) and Cd (II) from polluted aquatic media due to their easy synthesis and optimization process, and the possible reuses by efficient desorption in very low-cost conditions.
Published: 2019
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48. Two-Photon-Triggered Photorelease of Caged Compounds from Multifunctional Harmonic Nanoparticles

Author: Daniel Ortiz, Raphaël De Matos, Gabriel Campargue, Jérémy Vuilleumier, Yannick Mugnier, Christophe Mas, Luigi Bonacina, Laure Menin, Ronan Le Dantec, Geoffrey Gaulier, Samuel Constant, Sandrine Gerber-Lemaire, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Atheris Laboratories, Laboratoire SYstèmes et Matériaux pour la MEcatronique (SYMME), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry]), Université de Genève = University of Geneva (UNIGE), Group for Functionalized Biomaterials, Ecole Polytechnique Fédérale de Lausanne (EPFL), and Université de Genève (UNIGE)
Subjects: Materials science, Nanoparticle, ddc:500.2, 02 engineering and technology, Conjugated system, Light-triggered uncaging, 010402 general chemistry, Photochemistry, 01 natural sciences, Coumarin-based photosensitive tether, Nanomaterials, Two-photon excitation microscopy, General Materials Science, ComputingMilieux_MISCELLANEOUS, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, 3. Good health, 0104 chemical sciences, Covalent bond, Surface functionalization, Release quantification, Femtosecond, Surface modification, Harmonic nanoparticles, Nanocarriers, 0210 nano-technology
Abstract: The design of stimuli-responsive nanocarriers has raised much attention to achieve higher local concentration of therapeutics and mitigate the appearance of drug resistance. The combination of imaging properties and controlled photorelease of active molecules within the same nanoconjugate has a great potential for theranostic applications. In this study, a system for NIR light-triggered release of molecular cargos induced by the second harmonic emission from bismuth ferrite harmonic nanoparticles (BFO HNPs) is presented. Silica-coated BFO HNPs were covalently conjugated to a photocaging tether based on coumarin (CM) and l-tryptophan (Trp) as a model molecular cargo. Upon femtosecond pulsed irradiation at 790 nm, Trp was efficiently released from the NP surface in response to the harmonic emission of the nanomaterial at 395 nm. The emitted signal induced the photocleavage of the CM-Trp carbamate linkage resulting in the release of Trp, which was monitored and quantified by ultrahigh performance liquid chromatography-mass spectrometry (UHPLC-MS). While a small fraction of the uncaging process could be attributed to the nonlinear absorption of CM derivatives, the main trigger responsible for Trp release was established as the second harmonic signal from BFO HNPs. This strategy may provide a new way for the application of functionalized HNPs in dual imaging delivery theranostic protocols.
Published: 2019
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49. Development, characterization, and biological assessment of biocompatible cellulosic wound dressing grafted Aloe vera bioactive polysaccharide

Author: Faouzi Sakli, Nathalie Jarroux, Hatem Majdoub, Fatma Salah, Fahad M. Alminderej, Zouhour Ouanes, Olek Maciejak, Emna El Golli-Bennour, Yassine El Ghoul, Université de Monastir - University of Monastir (UM), Qassim University [Kingdom of Saudi Arabia], Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Laboratoire des Interfaces et Matériaux Avancés [Monastir] (LIMA), Faculté des Sciences de Monastir (FSM), and Université de Monastir - University of Monastir (UM)-Université de Monastir - University of Monastir (UM)
Subjects: Dressings, Polymers and Plastics, Biocompatibility, [SDV]Life Sciences [q-bio], 02 engineering and technology, Cotton, 010402 general chemistry, 01 natural sciences, Aloe vera, chemistry.chemical_compound, Response surface methodology, Acemannan grafting, [CHIM]Chemical Sciences, Acemannan, biology, Chemical modification, Biomaterial, 021001 nanoscience & nanotechnology, biology.organism_classification, Grafting, 0104 chemical sciences, Antibacterial, Cellulose fiber, chemistry, 0210 nano-technology, Antibacterial activity, Nuclear chemistry
Abstract: International audience; In order to improve healthcare of injured people, deacetylated acemannan extracted from Aloe vera leaves, having high inhibitory properties, was used as an antimicrobial finish on traditional cotton items. Response surface methodology was employed to define quadratic relationships between the polysaccharide grafting degree and the treatment process properties. An optimized modification process, offering the highest funtionalization degree, is obtained. The cellulosic fiber morphology and roughness modifications induced by polymer grafting are revealed using Atomic Force Microscopy and Scanning Electron Microscopy. Infra Red spectroscopy was used to confirm the grafting effectiveness. Thermogravimetric Analysis and Differential Scanning Calorimeter were further employed to confirm chemical modification. Considering the potential use of this new biomaterial, original properties were also studied. Finishing treatment seems to preserve mechanical properties, and hydrophilicity of the cellulosic substrate. MTT assay were done in HepG2 cells to ensure that the obtained dressings are non-toxic. The biomaterial showed high biocompatibility and promoted cell viability. Antimicrobial studies showed that grafting treatment conserved polymer antibacterial activity. Optimized cotton dressings exhibited a significant inhibitory effect against Staphylococcus aureus and Escherichia coli bacteria, killed respectively at 70.2% and 72.4%.
Published: 2019
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50. Aerolysin, a Powerful Protein Sensor for Fundamental Studies and Development of Upcoming Applications

Author: F. Gisou van der Goot, Benjamin Cressiot, Hadjer Ouldali, Juan Pelta, Manuela Pastoriza-Gallego, Laurent Bacri, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement (LAMBE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Université d'Évry-Val-d'Essonne (UEVE)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Saclay (COmUE), Ecole Polytechnique Fédérale de Lausanne (EPFL), and ANR-17-CE09-0044,EPSILOMICS,Système de puces nanofluidiques pour le dosage de biomarqueurs en quantité epsilon dans les échantillons biologiques humains(2017)
Subjects: Pore Forming Cytotoxic Proteins, [PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], Bacterial Toxins, Aerolysin, size and sequence discrimination, Bioengineering, Nanotechnology, 02 engineering and technology, single molecule, 01 natural sciences, label-free, Nanopores, toxin proaerolysin, Molecule, nanopore, Instrumentation, membrane-channel, electrical sensor, Fluid Flow and Transfer Processes, chemistry.chemical_classification, wild-type, Pore-forming toxin, Oligonucleotide, Process Chemistry and Technology, Biomolecule, protein unfolding, 010401 analytical chemistry, alpha-hemolysin, aeromonas-hydrophila, access resistance, confined medium dynamics, 021001 nanoscience & nanotechnology, molecule mass-spectrometry, lipid-bilayer, 0104 chemical sciences, Characterization (materials science), enzyme-activity, Nanopore, chemistry, Protein folding, 0210 nano-technology
Abstract: International audience; Nanopore electrical approach is a breakthrough in single molecular level detection of particles as small as ions, and complex as biomolecules. This technique can be used for molecule analysis, and characterization as well as for the understanding of confined medium dynamics in chemical or biological reactions. Altogether, the information obtained from these kinds of experiments will allow to address challenges in a variety of biological fields. The sensing, design and manufacture of nanopores is crucial to obtain these objectives. For some time now, aerolysin, a pore forming toxin, and its mutants have shown high potential in real time analytical chemistry, size discrimination of neutral polymers, oligosaccharides, oligonucleotides and peptides at monomeric resolution, sequence identification, chemical modification on DNA, potential biomarkers detection and protein folding analysis. This review focuses, on the results obtained with aerolysin nanopores on the fields of chemistry, biology, physics and biotechnology. We discuss and compare as well the results obtained with other protein channel sensors.
Published: 2019
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