1. Screening for Cryptococcal Antigenemia and Burden of Cryptococcosis at the Time of HIV Diagnosis: A Retrospective Multicenter Study
- Author
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Wen Chien Ko, Chun-Yuan Lee, Yuan-Ti Lee, Wang-Da Liu, Chia-Jui Yang, Chin Shiang Tsai, Chien-Ching Hung, Wei-Ting Hsu, Sung-Hsi Huang, Hsin-Yun Sun, Chun-Eng Liu, Po-Liang Lu, Hong-An Chen, and Mao-Song Tsai
- Subjects
0301 basic medicine ,Microbiology (medical) ,medicine.medical_specialty ,Cryptococcal antigen ,030106 microbiology ,HIV diagnosis ,03 medical and health sciences ,0302 clinical medicine ,Late presenter ,Internal medicine ,medicine ,Opportunistic infections ,030212 general & internal medicine ,Original Research ,Proportional hazards model ,business.industry ,Medical record ,Hazard ratio ,Care cascade ,medicine.disease ,People living with HIV ,Infectious Diseases ,Increased risk ,Multicenter study ,Cryptococcosis ,business ,Cryptococcal meningitis - Abstract
Introduction Screening for cryptococcal antigen (CrAg) is recommended for people living with HIV (PLWH) who present with low CD4 lymphocyte counts. Real-world experience is important to identify gaps between the guidelines and clinical practice. We investigated the trends of CrAg testing and prevalence of cryptococcal antigenemia among PLWH at the time of HIV diagnosis and the related mortality in Taiwan from 2009 to 2018. Methods Medical records of newly diagnosed PLWH seeking care at six medical centers around Taiwan between 2009 and 2018 were reviewed. The annual trends of PLWH who had CrAg testing and cryptococcal antigenemia were examined by Cochran-Armitage test. Among PLWH with CD4
- Published
- 2021