Search

The purpose of this study was to compare the tactical behaviours of soccer players who differed in their temporal distances from their respective peak height velocity (PHV). Seventy-eight soccer pl...

BACKGROUND: Asthma is a common respiratory disorder with a highly heterogeneous nature that remains poorly understood. The objective was to use whole genome sequencing (WGS) data to identify regions of common genetic variation contributing to lung function in individuals with a diagnosis of asthma. METHODS: WGS data were generated for 1,053 individuals from trios and extended pedigrees participating in the family-based Genetic Epidemiology of Asthma in Costa Rica study. Asthma affection status was defined through a physician’s diagnosis of asthma, and most participants with asthma also had airway hyperresponsiveness (AHR) to methacholine. Family-based association tests for single variants were performed to assess the associations with lung function phenotypes. RESULTS: A genome-wide significant association was identified between baseline FEV(1)/FVC ratio and a single-nucleotide polymorphism in the top hit cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2) (rs12051168; P = 3.6 × 10(−8) in the unadjusted model) that retained suggestive significance in the covariate-adjusted model (P = 5.6 × 10(−6)). Rs12051168 was also nominally associated with other related phenotypes: baseline FEV(1) (P = 3.3 × 10(−3)), postbronchodilator (PB) FEV(1) (7.3 × 10(−3)), and PB FEV(1)/FVC ratio (P = 2.7 × 10(−3)). The identified baseline FEV(1)/FVC ratio and rs12051168 association was meta-analyzed and replicated in three independent cohorts in which most participants with asthma also had confirmed AHR (combined weighted z-score P = .015) but not in cohorts without information about AHR. CONCLUSIONS: These findings suggest that using specific asthma characteristics, such as AHR, can help identify more genetically homogeneous asthma subgroups with genotype-phenotype associations that may not be observed in all children with asthma. CRISPLD2 also may be important for baseline lung function in individuals with asthma who also may have AHR.

Introduction: Among the main challenges faced by coaches of team sports are to create an environment and conditions that will enable players to reach their optimal level of physical performance at the start of the competitive season, and to maintain this level throughout the season. Objective: The purpose of this study was to assess the effects of six weeks of additional training with 3-against-3 (3v3) small-sided games (SSG) on the physical performance of elite nonstarter basketball players. Methods: Eleven professional basketball players (five starters and six nonstarters) performed the same training program throughout the regular season, with the only difference that after each game, the starters (S) performed low intensity shooting drills while the nonstarters (NS) performed half-court 3v3 SSG. At the start and end of the six-week period, the athletes were assessed for muscle power, speed, agility and aerobic power. Two-way analysis of variance and effect sizes were used. Magnitude-based inferential analyses were used to complement the parametric tests. Results: After the six weeks, the S and NS showed improvement (p

Differences in economic and social aspects between Brazilian states/regions can determine participation in running. The purpose of this study was to identify the occurrence of the OUTrun (i.e., Out Running), mapping the main routes carried out by runners, as well as the factors associated with this behavior between different Brazilian regions. The sample comprised 1053 runners of both sexes (women: 426, men: 627) who answered an online questionnaire, providing information related to individual, socioeconomic (SES), and training characteristics. A logistic regression analysis was computed, considering the regions. South and Southeast regions received the largest number of runners, runners from the North and Northeast regions were those who left their states the most to compete. Factors related to the OUTrun were the preferred distance, SES, and age. The results provide information to facilitate access to running events and can provide benefits related to making the practice accessible to a larger number of people.

Aims: to identify and describe the clustering of characteristics related to running amongst Brazilian runners using latent class analysis and to verify if there is a profile associated with better performance. Material and Methods: a sample of 1149 Brazilian runners answered an online questionnaire, that provided information about biological (sex, age, height, weight), training (running pace, frequency and volume/week, motivation), and socioeconomic factors, as well as a multidimensional questionnaire of fear of failure. Latent Class Analysis was used to identify subgroups of Brazilian runners, based on BMI, training volume and frequency/week, motivation, socioeconomic factors, and the fear of failure. Further, a χ2 test was computed to verify statistical differences in the frequency of the descriptive variables between classes. Finally, binary logistic regression analysis estimated factors associated with running performance, with running pace as the dependent variable. Results: It was possible to identify two different classes among Brazilian runners, which were called “amateur runners” and “recreational runners”. Variables that highlighted classes’ differences were: volume and frequency training/week, motivation for the practice, and BMI. Regarding the running performance, logistic regression analysis showed that men (OR=5.39; 95%CI=4.00-7.25), young runners (OR=0.38; 95%CI=0.28-0.51), and “amateur runners” (OR=4.19; 95%CI=2.95-5.94) were more prone to have higher performance. Conclusion: Two distinct classes were found among Brazilian runners that were linked to their performance, highlighting that even among non-professional runners, differences can be observed regarding their classification. Hence, future studies should consider using these classes to properly stratify or identify non-professional runners.

Tem-se observado, nos últimos anos, um aumento substancial no número de praticantes de corrida de rua no Brasil, os quais apresentam perfis e propósitos variados – alguns na busca pela competição/rendimento, outros com propósito de melhora de aspectos relacionados à saúde e qualidade de vida. Nesse sentido, o presente trabalho visa validar um instrumento que permita a caracterização deste público e a verificação do papel desempenhado por fatores de diferentes níveis no desempenho da corrida de rua. A amostra foi composta por 241 indivíduos, de ambos os sexos, com média de idade de 36,1 ± 10,3 anos, praticantes de corrida de rua no Brasil, dos quais 10%, aleatoriamente selecionados, responderam o instrumento duas vezes, respeitando-se o intervalo de um mês entre os dois momentos de resposta. O instrumento passou por dois processos de análise de conteúdo, realizada por avaliadores, seguida pela análise de reprodutibilidade, realizada pelo Coeficiente de Correlação Intraclasse (ICC) e o Coeficiente Kappa, o que indicou alta reprodutibilidade nas respostas, exceto para a variável “bairro de residência”. Assim, verifica-se que o presente instrumento pode ser utilizado na condução de pesquisas futuras, acrescendo os benefícios de sua aplicação no formato eletrônico, permitindo a aplicação em diferentes amostras, bem como a comparação de resultados entre sujeitos de diferentes locais, para além do fornecimento de informações que permitam a ampliação e compreensão acerca dos fatores associados ao desempenho na corrida de rua.

Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we use deep-coverage whole genome sequencing in 8392 individuals of European and African ancestry to discover and interpret both single-nucleotide variants and copy number (CN) variation associated with Lp(a). We observe that genetic determinants between Europeans and Africans have several unique determinants. The common variant rs12740374 associated with Lp(a) cholesterol is an eQTL for SORT1 and independent of LDL cholesterol. Observed associations of aggregates of rare non-coding variants are largely explained by LPA structural variation, namely the LPA kringle IV 2 (KIV2)-CN. Finally, we find that LPA risk genotypes confer greater relative risk for incident atherosclerotic cardiovascular diseases compared to directly measured Lp(a), and are significantly associated with measures of subclinical atherosclerosis in African Americans., Circulating lipoprotein(a) is an important risk factor for cardiovascular disease and shows variability between different ethnic groups. Here, Zekavat et al. perform whole-genome sequencing in individuals of European and African ancestries and find ancestry-specific genetic determinants for lipoprotein(a) levels.

The aim of this study was to analyze the effectiveness of long distance passes performed during the 2014 Brazil FIFA World Cup. All 64 matches were analyzed, however, actions performed during overtime were not included in the sample. The study defined long pass as an action made by a player from the defensive midfield aiming at passing the ball to another teammate located on the offensive field. The action result assessment followed these criteria: shots on goal, ball possession maintenance, loss of ball possession and ball possession recovery. Total long distance passes were also considered in the analysis. Throughout the tournament, 4,512 long distance passes were attempted. The main findings were that 59% resulted on loss, 28% on maintenance and 12% on recovery of the ball possession, but only less than 1% resulted in shots on goal (F = 505.5; p

Background There are a limited number of tests for the assessment of shoulder and pelvic girdle stability. Reliable instruments are important to evaluate movement dysfunction at these joints in order to provide more objective parameters. Objective To evaluate the inter-day reliability of the Upper Body Test in young adults. Methods A reliability study was carried out with three assessments of the shoulder and pelvic girdle stability within 48-h intervals (Monday, Wednesday, and Friday). The OctoBalance® platform was used to perform the Upper Body Test in 31 active young adults (24.5 ± 8 years). Intraclass Correlation Coefficient (ICC2,2) two-way mixed model, Coefficient of Variation, and Bland–Altman plots were used to verify the reliability of the test. The standard error of measurement (SEM) and the minimum detectable difference (MDD95%) were calculated for clinical applicability. Results The Intraclass Correlation Coefficient ranged from 0.87 to 0.94 – Featuring a mean difference of 0.89 (95%CI = −0.19–1.97) to left and 0.95 (95%CI = −0.38–2.27) for the right side, with a low variation coefficient (3.31–5.91%) between the second and third days of assessment. There was a statistically significant difference between the first assessment day and the other test sessions. The Bland–Altman analyses revealed low bias with scores within the limits of agreement. Minimum detectable difference scores were between 4.02 and 5.10, and standard error of measurement between 1.75 and 2.72, depending on the movement side. Conclusion The Upper Body Test presented good inter-day reliability for assessing the stability of the shoulder and pelvic girdle in young active healthy adults.

Resumo Objetivo: Avaliar os efeitos do treinamento de força sobre as hipertrofias renal e cardíaca induzida pela hipertensão renovascular em ratos. Método: Dezoito ratos Wistar foram divididos em três grupos: Sham, hipertenso (2K1C) e hipertenso treinado (2K1C-TR). Os animais foram induzidos a hipertensão renovascular através da ligadura da artéria renal esquerda. O treinamento de força foi iniciado quatro semanas após a indução da hipertensão renovascular, teve duração de 12 semanas e foi realizado a 70% de uma repetição máxima. Ao final foi medida pressão arterial, frequência cardíaca e parâmetros das hipertrofias renal e cardíaca. Resultados: O treinamento de força promoveu a redução da frequência cardíaca (p=0.0025) e da pressão arterial (p=0.01). Além disso, o treinamento diminuiu as massas absolutas do rim (p=0.0001) e coração (p=0.006), e os índices de hipertrofias renal e cardíaca, tanto normalizado pela massa corporal dos animais (p=0.0001 e p=0.001, respectivamente) como normalizado pelo comprimento da tíbia (p=0.004 e p=0.0004, respectivamente). Conclusão: O treinamento de força tem efeitos benéficos na hipertensão renovascular em animais, sendo capaz de reduzir a pressão arterial e a frequência cardíaca, além de atenuar o desenvolvimento das hipertrofias renal e cardíaca em ratos com hipertensão renovascular. Resumen Objetivo: Evaluar los efectos del entrenamiento de fuerza sobre las hipertrofias renal y cardíaca inducidas por la hipertensión renovascular en ratas. Método: Dieciocho ratas se dividieron en tres grupos: simulado, hipertenso (2R1C) e hipertenso entrenado (2R1C-TR). Los animales fueron inducidos a la hipertensión renovascular a través de la ligadura de la arteria renal izquierda. El entrenamiento de fuerza se inició cuatro semanas después de la inducción de la hipertensión renovascular, duró 12 semanas y se realizó al 70% de una repetición máxima. Al final se midió la presión arterial, la frecuencia cardiaca y los parámetros de las hipertrofias renal y cardíaca. Resultados: El entrenamiento de fuerza promovió la reducción de la frecuencia cardíaca (p=0.0025) y la presión arterial (p=0.01). Además el entrenamiento disminuyó las masas absolutas de los riñones (p=0.0001) y el corazón (p=0.006), y los índices de hipertrofias renal y cardíaca, tanto normalizado por la masa corporal de los animales (p=0.0001 e p=0.001, respectivamente) como normalizado por la longitud de la tibia (p=0.004 e p=0.0004, respectivamente). Conclusión: El entrenamiento de fuerza tiene efectos beneficiosos en la hipertensión renovascular en animales, siendo capaz de reducir la presión arterial y la frecuencia cardíaca, además de atenuar el desarrollo de las hipertrofias renal y cardíaca en ratas con hipertensión renovascular. Abstract Objective: To evaluate the effects of strength training on renal and cardiac hypertrophy induced by the renovascular hypertension in rats. Method: Eighteen male rats were divided into three groups: sham, hypertensive (2K1C) and trained hypertensive (2K1C-TR). The animals were induced to renovascular hypertension through ligation of the left renal artery. Strength training was initiated four weeks after the induction of renovascular hypertension, had the duration of 12 weeks and was performed at 70% of one maximum repetition. At the end, it was measured blood pressure, heart rate and parameters of renal and cardiac hypertrophies. Results: Strength training promoted reduction in heart rate (p=0.0025) and blood pressure (p=0.01). In addition, training decreased the absolute masses of the kidney (p=0.0001) and heart (p=0.006), and the indexes of renal and cardiac hypertrophy, both normalized by the body mass of the animals (p=0.0001 e p=0.001, respectively) and by the length of the tibia (p=0.004 e p=0.0004, respectively). Conclusion: Strength training has beneficial effects on renovascular hypertension in animals, being able to reduce blood pressure and heart rate, attenuating the development of renal and cardiac hypertrophies in rats with renovascular hypertension.

The ecological model theory highlights that human development (or a given behavior) is the result of the interaction of variables derived from different levels, comprising those directly related to the subjects and those related to the environment. Given that, the purpose of this study is to establish whether runners’ performance may vary among different Brazilian states, as the factors associated with this difference. The sample comprised 1151 Brazilian runners (61.8% men) that completed an online questionnaire, providing information about biological (sex, age, height, and weight), training (running pace, frequency and volume/week, and motivation), sociodemographic (place of residence and wage) aspects, and perceptions about the environmental influences on the practice. Information about state variables was obtained from official institutes, and comprised the human development index (HDI), athletics events, and violence index. Multilevel analysis was conducted in HLM software. State-level characteristics explained ≈3% of the total variance in running performance. Of the total variance explained for the individual level, 56.4% was associated with male sex (β = −54.98, p &lt, 0.001), age (β = 1.09, 0.001), body mass index (β = 6.86, 0.001), economic status (β = 6.23, p = 0.003), the perception of the natural environment (β = 7.58, p = 0.02), training frequency (β = −16.64, 0.001), and weekly volume (β = −0.30, 0.001). At the state level, only athletics events presented a positive and significant influence on performance. There is a significant role of the environment on the explanation of running performance variability, and given the diversity across states, environmental variables should not be neglected, as they are relevant to the exploration of other variables possibly related to running performance.

Background In leprosy, sensory function of nerves is evaluated with monofilaments test and the motor function with voluntary muscle test, however electroneuromyography is considered as the gold-standard tool. Objectives This study aimed: i) to evaluate the correlation between clinical tests and electroneuromyography for the diagnosis of leprosy neuropathy; and ii) to identify the prevalence of leprosy neuropathy and the most compromised peripheral nerves in leprosy. Methods We analysed the data from a nested case-control study that identified 166 patients diagnosed with leprosy neuropathy confirmed by electromyography. This study was designed for an analysis of correlation between the diagnostic tests. Results The most prevalent type of the neural damage was the sensory and motor multiple mononeuropathy, observed in 62 (37.3%) cases. The highest prevalence was the ulnar nerve in 67 (40.3%) cases. Agreement specified by nerves was moderate, ranging from k = 0.58 in the deep peroneal nerve to k = 0.41 in the posterior tibial nerve). Overall agreement between the clinical tests and electroneuromyography was very poor. Monofilaments test with k = 0.02 (95% CI 0.00-0.12) and voluntary muscle test with 0.16 (95% CI 0.04 to 0.28, P = 0.01). Conclusions There is a low to moderate correlation between clinical tests (monofilaments and voluntary muscle tests) and the electroneuromyography examination. The most prevalent type of neural impairment was the sensory and motor multiple mononeuropathy, and the most affected nerve was the ulnar.

Resumo O estudo verificou a evolução do basquetebol brasileiro a partir dos índices de desempenho (ID) das equipes em três temporadas do Novo Basquete Brasil (2009 a 2012) e determinou valores de referência (percentis) dos principais ID. Os dados foram coletados no site da Liga Nacional de Basquete. Foram analisados em 726 jogos os ID mais frequentes na análise do jogo de basquetebol pela ANOVA de um fator (post hoc de Tukey). A temporada 2011/12 apresentou menor número de arremessos de três pontos e maior de dois pontos, melhor aproveitamento nos lances livres e redução nos rebotes ofensivos. Os percentis indicam alto grau de exigência para a performance das equipes nos ID analisados. Nota-se uma tendência à modificação do estilo de jogo das equipes ao longo das três temporadas. Abstract The study examined the evolution of Brazilian basketball from the performance index (ID) teams in three seasons of Novo BasqueteBrasil (2009 to 2012), and determined reference values (percentiles) of the main ID. Data were collected on the website of the Brazilian National Basketball League. The most frequently ID in the analysis of the game of basketball were analyzed in 726 games by one-way ANOVA (post hoc Tukey). The 2011/12 season had less three-point and more two-points shots, showed an improvement on free-throws and a reduction in offensive rebounds. Percentiles indicate a high level demand for performance of teams among the ID analyzed. There was a tendency to change the game style of the teams over the past three seasons. Resumen El estudio examinó la evolución del baloncesto brasileño a partir de los índices de rendimiento (ID) de los equipos durante tres temporadas de Novo Basquete Brasil (de 2009 a 2012) y determinó los valores de referencia (percentiles) de los principales ID. Los datos se recopilaron en la página web de la Liga Nacional de Basquete. Se analizaron en 726 partidos por ANOVA de una vía (post hoc de Tukey). La temporada 2011-2012 tuvo menos tiros de tres puntos y más tiros de dos puntos, mostró una mejora en los tiros libres y una reducción en los rebotes ofensivos. Los percentiles indican un elevado grado de exigencia en el desempeño de los equipos de los ID analizados. Hubo una tendencia a cambiar el estilo de juego de los equipos durante las últimas tres temporadas.

Resumo Objetivo Determinar a validade e confiabilidade intra e interavaliadores da utilizacao de cronometros e videos para registro do tempo de execucao do Line Drill Test (LDT), comparando‐as a fotocelula. Metodo Vinte e dois atletas universitarios de basquetebol e handebol executaram o LDT em uma unica tentativa. O tempo de execucao foi registrado simultaneamente por fotocelula (padrao‐ouro) e avaliadores com cronometros manuais. Simultaneamente, o teste foi filmado para posterior analise por avaliadores cegados com relacao aos demais tempos obtidos. Foram determinados os seguintes indices: a) coeficiente de correlacao intraclasse; b) coeficiente de variacao; c) maxima diferenca absoluta para um mesmo teste; e d) erro tipico. Resultados Nao houve diferenca estatistica no uso dos equipamentos. As correlacoes interavaliador e entre os equipamentos foram elevadas (r = 0.993 a r = 1.000; p Conclusao Os resultados sugerem que a utilizacao de equipamentos de baixo custo (cronometros e câmeras) para registrar o tempo de execucao do LDTe valida e confiavel.

AIMS This study aimed to verify th erelation ship between of anthropometric and physical performance variables with game-related statistics in professional elite basketball players during a competition. METHODS Eleven male basketball players were evaluated during 10 weeks in two distinct moments (regular season and playoffs). Overall, 11 variables of physical fitness and 13 variables of game-related statistics were analysed. RESULTS The following significant Pearson’scorrelations were found in regular season: percentage of fat mass with assists (r = -0.62) and steals (r = -0.63); height (r = 0.68), lean mass (r = 0.64), and maximum strength (r = 0.67) with blocks; squat jump with steals (r = 0.63); and time in the T-test with success ful two-point field-goals (r = -0.65), success ful free-throws (r = -0.61), and steals (r = -0.62). However, in playoffs, only stature and lean mass maintained these correlations (p ≤ 0.05). CONCLUSIONS The anthropometric and physical characteristics of the players showed few correlations with the game-related statistics in regular season, and these correlations are even lower in the playoff games of a professional elite Champion ship, wherefore, not being good predictors of technical performance.

The objective of the present study is to evaluate and compare the effect of a nutritional intervention between adolescent and adult. In a before and after quasi-experimental clinical study, 32 athletes (21 adults, age range 20–32 years; 11 adolescents, age range: 12–19 years) participated in a nutritional counselling consisting of four consultations separated by an interval of 45 to 60 days. The athlete’s eating behaviour, body composition and nutrition knowledge were evaluated at the beginning and at the end of the protocol. Both groups increased lean body mass and nutritional knowledge. Adolescents increased their mid-arm muscle circumference and improved meal frequency, and daily water intake. Athletes of both groups improved their ingestion of vegetables and fruits and decreased the ingestion of sweets and oils. Adolescents showed a higher prevalence of individuals that remained within or approached to the recommendations of sweets. This is the first study to evaluate and compare the effect of a nutritional intervention between adolescent and adult athletes body composition, eating behaviour and nutritional knowledge. The nutritional counselling has been effective in promoting beneficial changes on the athlete’s eating behaviour, nutritional knowledge and body composition, however, some healthy changes were only experienced by adolescents, especially in the frequency of meals and the intake of sweets.

DOI: http://dx.doi.org/10.5007/1980-0037.2017v19n2p242 The aim of this research was to evaluate the performance and tactical behavior of youth soccer players of teams from base categories. The sample consisted of 152 male soccer players aged 11-17 years who participated in the in the U-13 (n = 50), U-15 (n = 62) and U-17 (n = 40) Sergipe State Championship in the year 2015. The System of Tactical Assessment in Soccer (FUT-SAT) was used to identify the players’ tactical behavior based on the fundamental tactical principles. The main results of the study show that players presented higher tactical offensive performance (50.8 ± 9.8 points) compared to defensive performance (34.3 ± 5.7 points) (p < 0.001; d = 2,1), and the Depth Mobility principle presented the highest performance indices in the offensive phase (64.1 ± 8.7; F = 54.4; p < 0.001; partial ƞ² = 0.26). Defensive Coverage showed the highest performance indexes in the defensive phase (46.1 ± 24.3; F = 54.4; p < 0.001; partial ƞ² = 0.26).