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Start Over Author "Chenavier, Yves" Topic 1,8-naphthalimide Topic fluorescence
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1. Thiazonaphthalimide derivatives: Synthesis and interaction with DNA.

Author

Botz, Alexandra, Chenavier, Yves, Pécaut, Jacques, Delangle, Pascale, and Gateau, Christelle

Subjects
*CHEMICAL synthesis, *ISOMERS, *FLUORESCENCE, *NUCLEAR magnetic resonance, *SINGLE crystals, *X-ray diffraction
Abstract

The synthesis of several thiazonaphthalimide derivatives is described. The exclusive formation of angular rather than linear isomers was unequivocally demonstrated by NMR and single crystal X-ray diffraction. Their photophysical properties and ability to bind calf-Thymus DNA with affinities in the range of 10 4 makes them interesting candidates to probe DNA by fluorescence. [ABSTRACT FROM AUTHOR]

Published
2018
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