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1. Lipoxygenase Inhibiting Two New Sterols from Capparis spinosa.

Author

Razaq, Abdul, Ahmed, Ejaz, Sharif, Ahsan, Rasool, Muhammad Azam, Arshad, Muhammad, Anjum, Muhammad Imran, Iqbal, Sajid, Sher, Muhammad, and Nawaz, Zahid

Subjects
*LIPOXYGENASES, *ENZYME inhibitors, *STEROLS, *CAPPARIS spinosa, *NUCLEAR magnetic resonance spectroscopy
Abstract

Spinosol A (1) and spinosol B (2) were isolated as new steroids from the chloroform soluble fraction of Capparis spinosa. The structures of both 1 and 2 were elucidated with the help of chemical tests and sophisticated spectroscopic techniques (1D and 2D NMR, EIMS, HREIMS). The compounds 1 and 2 showed significant inhibitory potential against the Lipoxygenase enzyme. [ABSTRACT FROM AUTHOR]

Published
2017

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