1. Diazinium salts with dihydroxyacetophenone skeleton: Syntheses and antimicrobial activity.
- Author
-
Balan AM, Florea O, Moldoveanu C, Zbancioc G, Iurea D, and Mangalagiu II
- Subjects
- Acetophenones pharmacology, Anti-Bacterial Agents pharmacology, Antifungal Agents pharmacology, Feasibility Studies, Green Chemistry Technology, Microbial Sensitivity Tests, Microwaves, Structure-Activity Relationship, Acetophenones chemical synthesis, Anti-Bacterial Agents chemical synthesis, Antifungal Agents chemical synthesis
- Abstract
Herein we report a feasible study concerning syntheses, structure and antimicrobial activity of some new diazinium salts with dihydroxyacetophenone skeleton. A fast, general, environmentally friendly, and facile method for preparation of diazinium salts under microwave and ultrasounds irradiation is presented. Antimicrobial tests prove that some diazine compounds have a remarkable activity against different microorganisms (germs and fungi), the pyrimidine derivatives being more active. Correlations between structure and antimicrobial activity are reported.
- Published
- 2009
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