19,270 results
Search Results
2. Could kinesiology taping of the inspiratory muscles help manage chronic breathlessness? An opinion paper.
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Banerjee, G., Rose, A., Briggs, M., Plant, P., and Johnson, M. I.
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TREATMENT of dyspnea ,RESPIRATORY muscles ,TAPING & strapping ,CHRONIC diseases ,PHYSICAL therapy ,TREATMENT effectiveness ,NURSES ,RESPIRATION ,ALTERNATIVE medicine ,PALLIATIVE treatment - Abstract
Chronic or refractory breathlessness adversely affects quality of life. Current treatment strategies for managing breathlessness are often inadequate in providing complete relief. Kinesiology taping is generally used in musculoskeletal practice for preventive and rehabilitative purposes. Recently, our attention was drawn to the plausible mechanism(s) and indication for use of kinesiology taping for managing chronic breathlessness. We present a brief review of the scientific rationale and efficacy of kinesiology taping for respiratory function-related outcomes. Through this publication, we hope to catalyse discussions amongst palliative care professionals and researchers on the potential use of kinesiology taping in the management of chronic breathlessness. [ABSTRACT FROM AUTHOR]
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- 2022
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3. Acupuncture Therapy as an Evidence-Based Nonpharmacologic Strategy for Comprehensive Acute Pain Care: The Academic Consortium Pain Task Force White Paper Update.
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Nielsen, Arya, Dusek, Jeffery A, Taylor-Swanson, Lisa, and Tick, Heather
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PERIOPERATIVE care , *ONLINE information services , *CINAHL database , *MEDICAL databases , *INTENSIVE care units , *HOSPITAL emergency services , *ACADEMIC medical centers , *OUTPATIENT medical care , *ACUPUNCTURE , *SYSTEMATIC reviews , *EVIDENCE-based medicine , *ALTERNATIVE medicine , *CONSORTIA , *MEDLINE , *PAIN management , *POSTOPERATIVE pain , *ACUTE diseases - Abstract
Background A crisis in pain management persists, as does the epidemic of opioid overdose deaths, addiction, and diversion. Pain medicine is meeting these challenges by returning to its origins: the Bonica model of multidisciplinary pain care. The 2018 Academic Consortium White Paper detailed the historical context and magnitude of the pain crisis and the evidence base for nonpharmacologic strategies. More than 50% of chronic opioid use begins in the acute pain care setting. Acupuncture may be able to reduce this risk. Objective This article updates the evidence base for acupuncture therapy for acute pain with a review of systematic reviews and meta-analyses on postsurgical/perioperative pain with opioid sparing and acute nonsurgical/trauma pain, including acute pain in the emergency department. Methods To update reviews cited in the 2018 White Paper, electronic searches were conducted in PubMed, MEDLINE, CINAHL, and the Cochrane Central Register of Controlled Trials for "acupuncture" and "acupuncture therapy" and "acute pain," "surgery," "peri-operative," "trauma," "emergency department," "urgent care," "review(s) ," "systematic review," "meta-analysis," with additional manual review of titles, links, and reference lists. Results There are 22 systematic reviews, 17 with meta-analyses of acupuncture in acute pain settings, and a review for acute pain in the intensive care unit. There are additional studies of acupuncture in acute pain settings. Conclusion The majority of reviews found acupuncture therapy to be an efficacious strategy for acute pain, with potential to avoid or reduce opioid reliance. Future multicenter trials are needed to clarify the dosage and generalizability of acupuncture for acute pain in the emergency department. With an extremely low risk profile, acupuncture therapy is an important strategy in comprehensive acute pain care. [ABSTRACT FROM AUTHOR]
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- 2022
- Full Text
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4. Naturopathy, complementary and integrative medicine in medical education – position paper by the GMA Committee Integrative Medicine and Perspective Pluralism.
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Homberg, Angelika, Scheffer, Christian, Brinkhaus, Benno, Fröhlich, Ulrike, Huber, Roman, Joos, Stefanie, Klose, Petra, Kramer, Klaus, Ortiz, Miriam, Rostock, Matthias, Valentini, Jan, and Stock-Schröer, Beate
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INTEGRATIVE medicine , *MEDICAL education , *ALTERNATIVE medicine , *NATUROPATHY , *MEDICAL care , *INTERPROFESSIONAL education - Abstract
Background: A large part of the population in Germany makes use of naturopathic, complementary and integrative medical treatments. There are now numerous scientific studies that provide evidence of efficacy for certain indications. At German medical faculties, selected procedures and their application are taught within the cross-sectoral unit called QB 12 and some elective courses, with a focus on specific aspects are offered. So far, however, there has been no structured curriculum that longitudinally anchors teaching across medical studies and enables all students to consider naturopathic and complementary medical options for patient care later on and to integrate them effectively into the diagnostic and treatment process. Objective: The aim of this position paper is to show the relevance of this topic for medical education, to clarify terminology and to present core competencies and possible implementation options for training. Method: The Integrative Medicine and Perspective Pluralism Committee of the German Association for Medical Education developed this position paper in a multi-stage consensual process, in cooperation with the Forum of University Work Groups on Naturopathic Treatment and Complementary Medicine. Results: First, different umbrella terms were discussed and an existing definition of integrative medicine and health was chosen for subsequent use. Building on this step, the status of education and its scientific foundation in Germany was considered in an international context. In the next step, a competency profile for medical training, consisting of seven areas of competency, was developed and described in detail with regard to naturopathic, complementary and integrative medicine. Implementation options were identified using possible starting points in the curriculum and using established examples of best practice. Conclusion: Despite different priorities at each faculty, it was possible to find an agreement on the development of competencies and anchoring them in medical education on the basis of a common definition of terms. Currently, the implementation in the mandatory and elective areas is very heterogeneous. As part of the current revision of the Medical Licensure Act, there are many possible starting points for the integration of naturopathic and complementary medical teaching content, especially in interprofessional and general practice courses. The implementation and accompanying research of targeted teaching settings should lay the foundations for a long-term and binding integration into medical education. Overall, it is clear that medical education in the field of naturopathy and complementary and integrative medicine has the potential to develop comprehensive core medical competencies. [ABSTRACT FROM AUTHOR]
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- 2022
- Full Text
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5. Publishing scientifically sound papers in Traditional and Complementary Medicine
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Ciro Isidoro
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Alternative medicine ,Complementary medicine ,Peer-reviewed journals ,Traditional medicine ,Journal of Traditional and Complementary Medicine ,Medicine - Abstract
Non-conventional medical practices that make use of dietary supplements, herbal extracts, physical manipulations, and other practices typically associated with folk and Traditional Medicine are increasingly becoming popular in Western Countries. These practices are commonly referred to by the generic, all-inclusive term “Complementary and Alternative Medicine.” Scientists, practitioners, and medical institutions bear the responsibility of testing and proving the effectiveness of these non-conventional medical practices in the interest of patients. In this context, the number of peer-reviewed journals and published articles on this topic has greatly increased in the recent decades. In this editorial article, we illustrate the policy of the Journal of Traditional and Complementary Medicine for publishing solid and scientifically sound papers in the field of Traditional and Complementary Medicine.
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- 2016
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6. Relationships and implications for complementary and alternative medicine in Aotearoa New Zealand : a discussion paper
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Te Huia, Maria and Mercer, Christine
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- 2019
7. The legacy and implications of the body-mind-spirit osteopathic tenet: A discussion paper evaluating its clinical relevance in contemporary osteopathic care
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Jorge E. Esteves, Francesco Cerritelli, Francesca Baroni, Jerry Draper-Rodi, Rafael Zegarra-Parodi, and Christian Lunghi
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030222 orthopedics ,medicine.medical_specialty ,business.industry ,Native american ,media_common.quotation_subject ,Alternative medicine ,Context (language use) ,Clinical Practice ,03 medical and health sciences ,0302 clinical medicine ,Complementary and alternative medicine ,medicine ,Musculoskeletal function ,Engineering ethics ,030212 general & internal medicine ,Sociocultural evolution ,business ,Diversity (politics) ,media_common - Abstract
A current osteopathic tenet inherited from Native American principles involves viewing each person as a dynamic interaction of body-mind-spirit (BMS). Because of its traditional medicine heritage and current evidence-based approach, the osteopathic profession is, arguably, uniquely positioned to promote evidence-informed person-centered approaches that transcend improvements in pain and musculoskeletal function. It may be particularly relevant in the context of integrating the BMS tenet into osteopathic care according to the diversity of patients’ values and sociocultural assumptions towards health, symptoms, and subsequent care, which range from the typical Western to complementary and alternative medicine perspectives. There is currently a lack of robust clinical practice frameworks in this area, confusing patients and practitioners and blurring professional identities. The current commentary provides an opportunity to initiate discussions in the profession with a rationale for creating a roadmap to develop an evidence-informed framework for osteopathic care that integrates the BMS tenet.
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- 2021
8. White Paper AGA: Functional Dyspepsia
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Nimish Vakil, Colin W. Howden, Paul Moayyedi, and Jan Tack
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medicine.medical_specialty ,Hepatology ,business.industry ,Treatment outcome ,Gastroenterology ,Alternative medicine ,medicine.disease ,Food and drug administration ,03 medical and health sciences ,0302 clinical medicine ,White paper ,Functional gastrointestinal disorder ,Internal medicine ,Family medicine ,medicine ,030211 gastroenterology & hepatology ,Patient-reported outcome ,030212 general & internal medicine ,business ,Pharmaceutical industry - Abstract
Functional dyspepsia remains a major challenge for clinicians with no approved drugs available in the Western World. In October 2016, a meeting was held in Washington, DC, sponsored by the American Gastroenterological Association's Center for Diagnostics and Therapeutics, which included members of the Food and Drug Administration (FDA) and the pharmaceutical industry, experts in FD, and representatives of patient organizations. This white paper summarizes our current status, progress with a validated patient reported outcome instrument in functional dyspepsia, future directions and needs.
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- 2017
9. White Paper on Natural Products
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Megan Musselman, Micheline Goldwire, Jennifer Phillips, Rena Gosser, Scot Walker, Scott A. Coon, Judith A. Smith, Anne L. Hume, Michael Gabay, Andrew M. Abe, and Mary L. Chavez
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medicine.medical_specialty ,Hospital setting ,Alternative medicine ,Pharmacists ,030226 pharmacology & pharmacy ,Natural (archaeology) ,Care setting ,03 medical and health sciences ,Professional Role ,0302 clinical medicine ,White paper ,Patient Education as Topic ,Patient-Centered Care ,Humans ,Medicine ,Pharmacology (medical) ,Community or ,030212 general & internal medicine ,Medical prescription ,Biological Products ,Traditional medicine ,business.industry ,Clinical pharmacy ,Family medicine ,Drug and Narcotic Control ,business ,Follow-Up Studies - Abstract
The American College of Clinical Pharmacy (ACCP) published an initial white paper on herbal products in 2000. Since then, the global market for natural products has continued to expand, with tens of millions of consumers using such products on an annual basis in the United States alone. However, despite this expansion, natural products remain largely unregulated compared with prescription medications, have moderate- to low-level clinical evidence for efficacy, and continue to have safety concerns, including adulteration and misbranding. As comprehensive medication management experts, clinical pharmacists are uniquely qualified to navigate these concerns and advise patients appropriately. To develop and recommend a suitable care plan involving natural products, clinical pharmacists must establish a strong pharmacist-patient relationship, assess the appropriateness of therapy, educate the patient regarding key issues, and continuously monitor and follow up on the effectiveness of the care plan. This process should not only occur in an individual community or hospital setting, but also whenever a patient transitions from one care setting to another in cooperation with other clinicians.
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- 2016
10. White Paper AGA: Gastroparesis: Clinical and Regulatory Insights for Clinical Trials
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Pankaj J. Pasricha, William L. Hasler, Michael Camilleri, and Henry P. Parkman
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medicine.medical_specialty ,Hepatology ,business.industry ,Clinical study design ,media_common.quotation_subject ,Gastroenterology ,Alternative medicine ,medicine.disease ,Article ,Surgery ,Clinical trial ,03 medical and health sciences ,Presentation ,0302 clinical medicine ,White paper ,Drug development ,030220 oncology & carcinogenesis ,medicine ,Clinical endpoint ,030211 gastroenterology & hepatology ,Gastroparesis ,Intensive care medicine ,business ,media_common - Abstract
Gastroparesis continues to represent a large unmet clinical need and a major opportunity for new drug development. This has led to increasing interest by federal funding agencies, regulatory bodies, and industry. This article summarizes the proceedings of the gastroparesis section of the “Drug Development Conference: Clinical Endpoints in Upper GI Disorders” organized by the American Gastroenterological Association in Washington, DC, on October 27–28, 2016. The presentation, diagnosis, and current therapeutic strategies are briefly reviewed, followed by a detailed discussion of the regulatory strategy, recommended endpoints, and future directions.
- Published
- 2017
11. Lost in translation? Comparing the effectiveness of electronic-based and paper-based cognitive aids
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Stuart Marshall
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medicine.medical_specialty ,Medical education ,Decision support system ,business.industry ,MEDLINE ,Alternative medicine ,030208 emergency & critical care medicine ,Cognition ,Paper based ,medicine.disease ,Checklist ,03 medical and health sciences ,0302 clinical medicine ,Anesthesiology and Pain Medicine ,Acquired immunodeficiency syndrome (AIDS) ,030202 anesthesiology ,Anesthesiology ,medicine ,business - Published
- 2017
12. A pragmatic randomized trial comparing tablet computer informed consent to traditional paper-based methods for an osteoporosis study
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Nicole C. Wright, Amy H. Warriner, Sebastian E. Sattui, Meredith L. Kilgore, Amy S. Mudano, Wilson D. Pace, Walter L. Calmbach, Phillip J. Foster, Jeffrey R. Curtis, Cora E. Lewis, Kenneth G. Saag, and Mary Elkins Melton
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medicine.medical_specialty ,Osteoporosis ,Alternative medicine ,Article ,law.invention ,Tablet computer ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,Informed consent ,law ,medicine ,030212 general & internal medicine ,Pharmacology ,lcsh:R5-920 ,business.industry ,General Medicine ,Paper based ,16. Peace & justice ,medicine.disease ,Pragmatic clinical trials ,3. Good health ,Clinical trial ,Comprehension ,030220 oncology & carcinogenesis ,Physical therapy ,business ,lcsh:Medicine (General) - Abstract
Objective Methods to improve informed consent efficiency and effectiveness are needed for pragmatic clinical trials. We compared informed consent using a tablet computer to a paper approach to assess comprehension and satisfaction of patients and clinic staff for a future osteoporosis clinical trial. Methods Nine community-based practices identified and recruited patients to compare the informed consent processes (tablet vs. paper) in a mock osteoporosis clinical trial. The tablet informed consent included an animation summarizing the trial, complete informed consent document, and questions to assess and reinforce comprehension of the study. Participants were women age ≥55 years with ≥1 year of alendronate use. We surveyed participants to assess comprehension and satisfaction and office staff for satisfaction and perceived time demands. Results The nine practices enrolled 33 participants. There was not a significant difference in comprehension between the tablet vs. paper informed consent [mean (SD) tablet: 12.2 (1.0) vs. paper: 11.4 (1.7)]. Office staff preferred the tablet to the paper informed consent for identifying potential study participants (two-sided t-test p = 0.02) despite an increased perceived time spent to complete the tablet process [tablet: 28.3 min (SD 16.3) vs. paper: 19.0 min (SD 6.9); p = 0.08]. Conclusions Although, there were no significant differences in participant satisfaction and comprehension with the tablet informed consent compared to a paper informed consent, patients and office staff trended towards greater satisfaction with the tablet informed consent. Larger studies are needed to further evaluate the utility of electronic informed consent in pragmatic clinical trials.
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- 2016
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13. Postural assessment in pen-and-paper-based observational methods and their associated health effects: a review
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Baba Md Deros, Ahmad Rasdan Ismail, Nur Syazwani Mohd Nawi, Jaharah A Ghani, and Ezrin Hani Sukadarin
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Upper Arms ,medicine.medical_specialty ,Work activity ,Posture ,Alternative medicine ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Adverse health effect ,Humans ,Medicine ,0501 psychology and cognitive sciences ,Musculoskeletal Diseases ,Safety, Risk, Reliability and Quality ,050107 human factors ,business.industry ,05 social sciences ,Public Health, Environmental and Occupational Health ,Human factors and ergonomics ,Paper based ,Observational methods in psychology ,030210 environmental & occupational health ,Occupational Diseases ,Physical therapy ,Observational study ,Ergonomics ,business ,Safety Research - Abstract
This review describes standardized ergonomics assessment based on pen-and-paper observational methods for assessing ergonomics risk factors.The three main objectives are to analyze published pen-and-paper observational methods, to extract and understand the risk levels of each method and to identify their associated health effects.The authors searched scientific databases and the Internet for materials from 1970 to 2013 using the following keywords: ergo, posture, method, observational, postural angle, health effects, pain and diseases. Postural assessments of upper arms, lower arms, wrists, neck, back and legs in six pen-and-paper-based observational methods are highlighted, extracted in groups and linked with associated adverse health effects.The literature reviewed showed strengths and limitations of published pen-and-paper-based observational methods in determining the work activities, risk levels and related postural angles to adverse health effects. This provided a better understanding of unsafe work postures and how to improve these postures.Many pen-and-paper-based observational methods have been developed. However, there are still many limitations of these methods. There is, therefore, a need to develop a new pen-and-paper-based observational method for assessing postural problems.
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- 2016
14. European Pain Federation position paper on appropriate opioid use in chronic pain management
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Asbjørn Mohr Drewes, Bart Morlion, Marie Fallon, Hans G. Kress, Esther M. Pogatzki-Zahn, Henry J McQuay, G Mikus, J Perez-Cajaraville, Giustino Varrassi, Jcd Wells, Tony O'Brien, and Lona L. Christrup
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medicine.medical_specialty ,Attitude of Health Personnel ,Pain medicine ,Alternative medicine ,Chronic noncancer pain ,Driving ability ,03 medical and health sciences ,0302 clinical medicine ,Clinical Protocols ,Journal Article ,medicine ,Prevalence ,Humans ,Pain Management ,030212 general & internal medicine ,Practice Patterns, Physicians' ,Cancer pain ,Psychiatry ,Intensive care medicine ,Induced bowel dysfunction ,Toxicity ,business.industry ,Patient Selection ,Public health ,Long-term treatment ,Chronic pain ,Primary care physician ,Double-blind ,Oxycodone/naloxone ,medicine.disease ,Analgesics, Opioid ,Europe ,Anesthesiology and Pain Medicine ,Pain Clinics ,Induced constipation ,Position paper ,Position Paper ,Chronic Pain ,business ,030217 neurology & neurosurgery - Abstract
UNLABELLED: Poorly controlled pain is a global public health issue. The personal, familial and societal costs are immeasurable. Only a minority of European patients have access to a comprehensive specialist pain clinic. More commonly the responsibility for chronic pain management and initiating opioid therapy rests with the primary care physician and other non-specialist opioid prescribers. There is much confusing and conflicting information available to non-specialist prescribers regarding opioid therapy and a great deal of unjustified fear is generated. Opioid therapy should only be initiated by competent clinicians as part of a multi-faceted treatment programme in circumstances where more simple measures have failed. Throughout, all patients must be kept under close clinical surveillance. As with any other medical therapy, if the treatment fails to yield the desired results and/or the patient is additionally burdened by an unacceptable level of adverse effects, the overall management strategy must be reviewed and revised. No responsible clinician will wish to pursue a failed treatment strategy or persist with an ineffective and burdensome treatment. In a considered attempt to empower and inform non-specialist opioid prescribers, EFIC convened a European group of experts, drawn from a diverse range of basic science and relevant clinical disciplines, to prepare a position paper on appropriate opioid use in chronic pain. The expert panel reviewed the available literature and harnessed the experience of many years of clinical practice to produce these series of recommendations. Its success will be judged on the extent to which it contributes to an improved pain management experience for chronic pain patients across Europe. SIGNIFICANCE: This position paper provides expert recommendations for primary care physicians and other non- specialist healthcare professionals in Europe, particularly those who do not have ready access to specialists in pain medicine, on the safe and appropriate use of opioid medications as part of a multi-faceted approach to pain management, in properly selected and supervised patients. ispartof: European Journal of Pain vol:21 issue:1 pages:3-19 ispartof: location:England status: published
- Published
- 2017
15. Position paper Statin intolerance – an attempt at a unified definition. Position paper from an International Lipid Expert Panel
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Dimitri P. Mikhailidis, Assen Goudev, Manfredi Rizzo, Robert S. Greenfield, Daniel Lighezan, Karam Kostner, Richard Ceska, Dragan M. Djuric, Maciej Banach, Wilbert S. Aronow, Daniel Pella, Michael H. Davidson, Nathan D. Wong, Corina Serban, Marlena Broncel, Marat V. Ezhov, Jacek Rysz, Stephen J. Nicholls, Steven R. Jones, Peter P. Toth, Kausik K. Ray, Raman Puri, Vasilis G. Athyros, Paul Muntner, Zlatko Fras, Michel Farnier, Laszlo Bajnok, Dragana Nikolic, Khalid Al-Rasadi, Patrick M. Moriarty, and G. Kees Hovingh
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medicine.medical_specialty ,Statin ,business.industry ,medicine.drug_class ,Alternative medicine ,Placebo-controlled study ,nutritional and metabolic diseases ,General Medicine ,Disease ,computer.software_genre ,3. Good health ,law.invention ,Randomized controlled trial ,law ,Post-hoc analysis ,medicine ,Position paper ,lipids (amino acids, peptides, and proteins) ,cardiovascular diseases ,Data mining ,business ,Intensive care medicine ,Adverse effect ,computer - Abstract
Statins are one of the most commonly prescribed drugs in clinical practice. They are usually well tolerated and effectively prevent cardiovascular events. Most adverse effects associated with statin therapy are muscle-related. The recent statement of the European Atherosclerosis Society (EAS) has focused on statin associated muscle symptoms (SAMS), and avoided the use of the term 'statin intolerance'. Although muscle syndromes are the most common adverse effects observed after statin therapy, excluding other side effects might underestimate the number of patients with statin intolerance, which might be observed in 10-15% of patients. In clinical practice, statin intolerance limits effective treatment of patients at risk of, or with, cardiovascular disease. Knowledge of the most common adverse effects of statin therapy that might cause statin intolerance and the clear definition of this phenomenon is crucial to effectively treat patients with lipid disorders. Therefore, the aim of this position paper was to suggest a unified definition of statin intolerance, and to complement the recent EAS statement on SAMS, where the pathophysiology, diagnosis and the management were comprehensively presented.
- Published
- 2015
16. Remembering Wing Yuen Lee: surprises, silences and subtexts in oral testimony [Paper in: Islands of Memory.]
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Boileau, Joanna
- Published
- 2009
17. Challenges and Opportunities Faced by Biofield Practitioners in Global Health and Medicine: A White Paper
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Rauni Prittinen King and Erminia Guarneri
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Licensure ,Medical education ,medicine.medical_specialty ,education ,business.industry ,Alternative medicine ,Core competency ,General Medicine ,Original Articles ,Interprofessional education ,030205 complementary & alternative medicine ,03 medical and health sciences ,0302 clinical medicine ,White paper ,practitioner ,Energy medicine ,030220 oncology & carcinogenesis ,Family medicine ,Health care ,Global health ,medicine ,energy medicine ,business ,profession ,Biofield - Abstract
Biofield therapies (BTs) are increasingly employed in contemporary healthcare. In this white paper, we review specific challenges faced by biofield practitioners resulting from a lack of (1) a common scientific definition of BT; (2) common educational standards for BT training (including core competencies for clinical care); (3) collaborative team care education in complementary and alternative medicine (CAM) and in integrative health and medicine (IHM); (4) a focused agenda in BT research; and (5) standardized devices and scientifically validated mechanisms in biofield research. We present a description of BT and discuss its current status and challenges as an integrative healthcare discipline. To address the challenges cited and to enhance collaboration across disciplines, we propose (1) standardized biofield education that leads to professional licensure and (2) interprofessional education (IPE) competencies in BT training required for licensed healthcare practitioners and encouraged for other practitioners using these therapies. Lastly, we discuss opportunities for growth and a potential strategic agenda to achieve these goals. The Academy of Integrative Health and Medicine (AIHM) provides a unique forum to facilitate development of this emerging discipline, to facilitate IPE, and to further increase the availability of BT to patients.
- Published
- 2015
18. Evidence and expert opinions: Dry needling versus acupuncture (III) — The American Alliance for Professional Acupuncture Safety (AAPAS) White Paper 2016
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Arthur Yin Fan, Yong-ming Li, and Jun Xu
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China ,medicine.medical_specialty ,Consensus ,Acupuncture Therapy ,MEDLINE ,Alternative medicine ,Myofascial pain syndrome ,030226 pharmacology & pharmacy ,03 medical and health sciences ,0302 clinical medicine ,White paper ,Physicians ,Acupuncture ,medicine ,Humans ,Pharmacology (medical) ,Cooperative Behavior ,Myofascial Pain Syndromes ,Expert Testimony ,Societies, Medical ,Dry needling ,Health professionals ,Traditional medicine ,business.industry ,Myofascial pain ,General Medicine ,medicine.disease ,United States ,030205 complementary & alternative medicine ,Alliance ,Complementary and alternative medicine ,Needles ,Ashi ,Practice Guidelines as Topic ,Physical therapy ,Acupuncture needle ,business ,Acupuncture Points ,030217 neurology & neurosurgery - Abstract
In the United States and other Western countries, dry needling has been a topic in academic and legal fields. This White Paper is to provide the authoritative information of dry needling versus acupuncture to academic scholars, healthcare professionals, administrators, policymakers, and the general public by providing the authoritative evidence and expertise regarding critical issues of dry needling and reaching a consensus. We conclude that Dr. Travell, Dr. Gunn, Dr. Baldry and others who have promoted dry needling by simply rebranding (1) acupuncture as dry needling and (2) acupuncture points as trigger points (dry needling points). Dry needling simply using English biomedical terms (especially using "fascia" hypothesis) in replace of their equivalent Chinese medical terms. Dry needling is an over-simplified version of acupuncture derived from traditional Chinese acupuncture except for emphasis on biomedical language when treating neuromuscularskeletal pain (dry needling promoters redefined it as "myofascial pain"). Trigger points belong to the category of Ashi acupuncture points in traditional Chinese acupuncture, and they are not a new discovery. By applying acupuncture points, dry needling is actually trigger point acupuncture, an invasive therapy (a surgical procedure) instead of manual therapy. Dr. Travell admitted to the general public that dry needling is acupuncture, and acupuncture professionals practice dry needling as acupuncture therapy and there are several criteria in acupuncture profession to locate trigger points as acupuncture points. Among acupuncture schools, dry needling practitioners emphasize acupuncture's local responses while other acupuncturists pay attention to the responses of both local, distal, and whole body responses. For patients' safety, dry needling practitioners should meet standards required for licensed acupuncturists and physicians.
- Published
- 2017
19. Non-insulin antidiabetic pharmacotherapy in patients with established cardiovascular disease:a position paper of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy
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Sven Wassmann, Thomas Walther, Gianluigi Savarese, Juan Carlos Kaski, Juan Tamargo, Basil S. Lewis, Christian Torp-Pedersen, Thomas Andersen Schmidt, Claudio Ceconi, Christoph H. Saely, Lorenz Koller, Alexander Niessner, Keld Kjeldsen, Stefan Agewall, Giuseppe M.C. Rosano, and Heinz Drexel
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safety ,medicine.medical_specialty ,medicine.medical_treatment ,Cardiology ,Myocardial Infarction ,Alternative medicine ,MEDLINE ,Disease ,030204 cardiovascular system & hematology ,outcomes ,Incretins ,Glucagon-Like Peptide-1 Receptor ,drugs ,NO ,03 medical and health sciences ,0302 clinical medicine ,Pharmacotherapy ,et-al ,prevention ,Internal medicine ,Diabetes mellitus ,inhibitors ,medicine ,Journal Article ,Humans ,Hypoglycemic Agents ,Glycoside Hydrolase Inhibitors ,In patient ,030212 general & internal medicine ,Sodium-Glucose Transporter 2 Inhibitors ,Societies, Medical ,risk ,Glycated Hemoglobin ,Dipeptidyl-Peptidase IV Inhibitors ,Diabetes-mellitus ,business.industry ,heart-failure ,Insulin ,medicine.disease ,Metformin ,Europe ,Stroke ,events ,Diabetes Mellitus, Type 2 ,Cardiovascular Diseases ,Position paper ,Cardiology and Cardiovascular Medicine ,business - Published
- 2018
20. Patient preference: a comparison of electronic patient-completed questionnaires with paper among cancer patients
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M.C. Brown, Petra Martin, Christine Lam, Chongya Niu, Wei Xu, Mary Mahler, M. Otsuka, Dan Pringle, H. Hon, Sinead Cuffe, Jodie Villeneuve, Rebecca Charow, Osvaldo Espin-Garcia, Geoffrey Liu, Shabbir M.H. Alibhai, Jodie Jenkinson, and Ravi M. Shani
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Adult ,Male ,Paper ,medicine.medical_specialty ,Multivariate analysis ,020205 medical informatics ,education ,Alternative medicine ,02 engineering and technology ,Affect (psychology) ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Neoplasms ,Surveys and Questionnaires ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,Humans ,Aged ,Genetic testing ,Aged, 80 and over ,Internet ,medicine.diagnostic_test ,Computers ,business.industry ,Significant difference ,Age Factors ,Cancer ,Patient Preference ,Middle Aged ,medicine.disease ,Patient preference ,Preference ,Oncology ,Computers, Handheld ,030220 oncology & carcinogenesis ,Family medicine ,Multivariate Analysis ,Female ,Comprehension ,business - Abstract
In this study, we compared cancer patients preference for computerised (tablet/web-based) surveys versus paper. We also assessed whether the understanding of a cancer-related topic, pharmacogenomics is affected by the survey format, and examined differences in demographic and medical characteristics which may affect patient preference and understanding. Three hundred and four cancer patients completed a tablet-administered survey and another 153 patients completed a paper-based survey. Patients who participated in the tablet survey were questioned regarding their preference for survey format administration (paper, tablet and web-based). Understanding was assessed with a ‘direct’ method, by asking patients to assess their understanding of genetic testing, and with a ‘composite’ score. Patients preferred administration with tablet (71%) compared with web-based (12%) and paper (17%). Patients
- Published
- 2015
21. Nutritional Support in Cancer Patients: A Position Paper from the Italian Society of Medical Oncology (AIOM) and the Italian Society of Artificial Nutrition and Metabolism (SINPE)
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Paolo Pedrazzoli, Giordano D. Beretta, Mariateresa Nardi, Agostino Paccagnella, Alessandro Laviano, Carmine Pinto, Emanuele Cereda, Cecilia Gavazzi, Vittorina Zagonel, and Riccardo Caccialanza
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Pediatrics ,Palliative care ,Alternative medicine ,Review ,Clinical nutrition ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Medicine ,Nutritional support ,Intensive care medicine ,Cancer ,030109 nutrition & dietetics ,business.industry ,Malnutrition ,medicine.disease ,Clinical trial ,Oncology ,030220 oncology & carcinogenesis ,Position paper ,business - Abstract
Malnutrition is a frequent problem in cancer patients, which leads to prolonged hospitalization, a higher degree of treatment-related toxicity, reduced response to cancer treatment, impaired quality of life and a worse overall prognosis. The attitude towards this issue varies considerably and many malnourished patients receive inadequate nutritional support. We reviewed available data present in the literature, together with the guidelines issued by scientific societies and health authorities, on the nutritional management of patients with cancer, in order to make suitable and concise practical recommendations for appropriate nutritional support in this patient population. Evidence from the literature suggests that nutritional screening should be performed using validated tools (the Nutritional Risk Screening 2002 [NRS 2002], the Malnutrition Universal Screening Tool [MUST], the Malnutrition Screening Tool [MST] and the Mini Nutritional Assessment [MNA]), both at diagnosis and at regular time points during the course of disease according to tumor type, stage and treatment. Patients at nutritional risk should be promptly referred for comprehensive nutritional assessment and support to clinical nutrition services or medical personnel with documented skills in clinical nutrition, specifically for cancer patients. Nutritional intervention should be actively managed and targeted for each patient; it should comprise personalized dietary counseling and/or artificial nutrition according to spontaneous food intake, tolerance and effectiveness. Nutritional support may be integrated into palliative care programs. “Alternative hypocaloric anti-cancer diets” (e.g. macrobiotic or vegan diets) should not be recommended as they may worsen nutritional status. Well-designed clinical trials are needed to further our knowledge of the nutritional support required in different care settings for cancer patients.
- Published
- 2016
22. Position paper update: Whole bowel irrigation for gastrointestinal decontamination of overdose patients
- Author
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Régis Bedry, Kalle Hoppu, Bill Troutman, Andrew R. Erdman, Blaine Jess Benson, Ruben Thanacoody, E. Martin Caravati, Bruno Mégarbane, and Jonas Höjer
- Subjects
medicine.medical_specialty ,business.industry ,Alternative medicine ,Context (language use) ,General Medicine ,Lithium ,Clinical toxicology ,Toxicology ,Gastrointestinal decontamination ,Surgery ,Gastrointestinal Tract ,Charcoal ,medicine ,Animals ,Humans ,Position paper ,Drug Overdose ,Therapeutic Irrigation ,business ,Intensive care medicine ,Whole bowel irrigation ,Decontamination - Abstract
A position paper on the use of whole bowel irrigation (WBI) was first published in 1997 by the American Academy of Clinical Toxicology (AACT) and the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) and updated in 2004. The aims of this paper are to briefly summarize the content of the 2004 Position Paper and to present any new data and recommendations.A systematic review of the literature from January 2003 to February 28, 2013 was conducted using multiple online databases for articles concerning WBI for gastrointestinal decontamination. An evidence table was created for applicable articles. The authors produced the initial draft that was reviewed by AACT and EAPCCT.The literature search produced 60 articles with the possibility of applicable human data. Based mainly on volunteer studies, WBI can be considered for potentially toxic ingestions of sustained-release or enteric-coated drugs particularly for those patients presenting later than 2 h after drug ingestion when activated charcoal is less effective. WBI can be considered for patients who have ingested substantial amounts of iron, lithium, or potassium as the morbidity is high and there is a lack of other potentially effective options for gastrointestinal decontamination. WBI can be considered for removal of ingested packets of illicit drugs in "body packers." However, controlled data documenting improvement in clinical outcome after WBI are lacking. WBI is contraindicated in patients with bowel obstruction, perforation, or ileus, and in patients with hemodynamic instability or compromised unprotected airways. WBI should be used cautiously in debilitated patients and in patients with medical conditions that might be further compromised by its use. The concurrent administration of activated charcoal and WBI might decrease the effectiveness of the charcoal. The clinical relevance of this interaction is uncertain.WBI can facilitate removal of select toxicants from the gastrointestinal tract in some patients, but there is no convincing evidence from clinical studies that it improves the outcome of poisoned patients. There is no new evidence that would require a major revision of the conclusions of the 2004 position statement.
- Published
- 2014
23. Full text publication rates of papers presented at the British Foot and Ankle Society
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A Mumith, Heath Taylor, and Daniel Marsland
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medicine.medical_specialty ,Biomedical Research ,Scrutiny ,Evidence-based practice ,Databases, Factual ,media_common.quotation_subject ,Alternative medicine ,Bibliometrics ,03 medical and health sciences ,Presentation ,0302 clinical medicine ,medicine ,Humans ,Orthopedic Procedures ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,Societies, Medical ,media_common ,030222 orthopedics ,Medical education ,Foot ,business.industry ,Publications ,Foot and ankle surgery ,United Kingdom ,British Foot ,Orthopedics ,medicine.anatomical_structure ,Ankle ,business - Abstract
Background Techniques in foot and ankle surgery have expanded rapidly in recent years, often presented at national society meetings. It is important that research is published to guide evidence based practice. Many abstracts however do not go on to full text publication. Methods A database was created of all abstracts presented at BOFAS meetings from 2009 to 2013. Computerised searches were performed using PubMed and Google search engines. Results In total 341 papers were presented, with an overall publication rate of 31.7%. Of 251 clinical papers, 200 were case series (79.6%). Factors associated with publication success included basic science studies, papers related to arthroscopic surgery and research performed outside the UK. Conclusion A relatively low conversion rate from presentation to publication could be as a result of papers failing to pass the scrutiny of peer review, or that the work is never formally submitted for publication. The information from this study could be used to prioritise future research and promote higher quality research.
- Published
- 2018
24. Quality of life measurement in acne. Position Paper of the European Academy of Dermatology and Venereology Task Forces on Quality of Life and Patient Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa
- Author
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Andrew Yule Finlay, Andrea W M Evers, Servando E Marron, Clio Dessinioti, Lucia Tomas-Aragones, Françoise Poot, Gregor B.E. Jemec, Thrasyvoulos Tzellos, Vincenzo Bettoli, Francesca Sampogna, Aikaterini I. Liakou, O. D. van Cranenburgh, Mir-saeed Salek, Christos C. Zouboulis, Jacek C Szepietowski, Åke Svensson, L. Manolache, Pavel V Chernyshov, and Medical Psychology
- Subjects
medicine.medical_specialty ,Venereology ,Alternative medicine ,Dermatology ,Validation Studies as Topic ,Task (project management) ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Surveys and Questionnaires ,Acne Vulgaris ,medicine ,Humans ,Hidradenitis suppurativa ,030212 general & internal medicine ,Acne ,Clinical Trials as Topic ,business.industry ,Reproducibility of Results ,medicine.disease ,R1 ,humanities ,Infectious Diseases ,Rosacea ,Quality of Life ,Inflammatory diseases Radboud Institute for Health Sciences [Radboudumc 5] ,Position paper ,business - Abstract
Item does not contain fulltext Acne causes profound negative psychological and social effects on the quality of life (QoL) of patients. The European Dermatology Forum S3-Guideline for the Treatment of Acne recommended adopting a QoL measure as an integral part of acne management. Because of constantly growing interest in health-related QoL assessment in acne and because of the high impact of acne on patients' lives, the European Academy of Dermatology and Venereology Task Force on QoL and Patient Oriented Outcomes and the Task Force on Acne, Rosacea and Hidradenitis Suppurativa have documented the QoL instruments that have been used in acne patients, with information on validation, purposes of their usage, description of common limitations and mistakes in their usage and overall recommendations.
- Published
- 2017
25. Review of prolotherapy for musculoskeletal pain and disability: a White Paper for the Australasian Faculty of Musculoskeletal Medicine
- Author
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Yelland, M
- Published
- 2002
26. Adding to the cannabis debate: Comment on various Central Drug Authority papers
- Author
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Keith Scott
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medicine.medical_specialty ,Civil society ,Harm reduction ,biology ,business.industry ,Cannabinoids ,Illicit Drugs ,Substance-Related Disorders ,Alternative medicine ,General Medicine ,Public relations ,biology.organism_classification ,Public opinion ,South Africa ,Harm ,Drug control ,Harm Reduction ,Public Opinion ,medicine ,Government Regulation ,Position paper ,Drug and Narcotic Control ,Humans ,Cannabis ,business - Abstract
This editorial addresses the following documents published in this and a previous edition of the SAMJ:The Central Drug Authority (CDA)'s position paper on cannabisThe CDA's position paper on harm reductionThe CDA's response to the editorial 'Comment on the CDA's position statement on cannabis'. As there is considerable overlap between the contents of the above documents, this editorial tries to avoid covering all the arguments put forward both in these documents and in the author's 'Comment on the CDA's position statement on cannabis'. Instead, it sets out to inform medical professionals and civil society why the incorporation of illicit drugs into the existing regulatory framework of drug control is the only holistic way to implement comprehensive harm reduction measures and bring an end to the 'war on drugs'.Instead it sets out to inform medical professionals and civil society as to why the incorporation of illicit drugs into the existing regulatory framework of drug control is the only holistic way to both implement comprehensive harm reduction measures and bring an end to the 'war on drugs'.
- Published
- 2016
27. Fibromyalgia and Chronic Pain Syndromes: A White Paper Detailing Current Challenges in the Field
- Author
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Takahiro Ushida, Guochun Wang, Richard E. Harris, Daniel J. Clauw, Don L. Goldenberg, Koichi Noguchi, Troels S. Jensen, Ernest Choy, Stuart L. Silverman, Milton Helfenstein, and Lesley M. Arnold
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,unified diagnostic guidelines ,Alternative medicine ,interprofessional collaboration ,Primary care ,Key issues ,central amplification ,03 medical and health sciences ,0302 clinical medicine ,White paper ,Fibromyalgia ,medicine ,central sensitivity syndromes ,Intensive care medicine ,sensory hypersensitivity ,030203 arthritis & rheumatology ,neuroimaging ,business.industry ,Chronic pain ,chronic widespread pain ,medicine.disease ,Research findings ,humanities ,nervous system diseases ,Anesthesiology and Pain Medicine ,Physical therapy ,Research studies ,regulatory pathway ,fibromyalgia ,Neurology (clinical) ,business ,central pain ,030217 neurology & neurosurgery - Abstract
Pfizer Inc., New York, NY Dainippon Sumitomo Pharma, Tokyo, Japan Innovative Med Concepts LLC (IMC), Tuscaloosa, AL Ironwood Pharmaceuticals, Cambridge, MA Purdue Pharma, Stamford, CT Shire, Lexington, MA Theravance Biopharma, South San Francisco, CA Toray, Tokyo, Japan Eli Lilly and Company, Indianapolis, IN Forest Laboratories, New York, NY Tonix Pharmaceuticals, New York, NY Cerephex Corporation, Los Altos, CA National Institutes of Health, Bethesda, MD National Institutes of Health Grunenthal, Aachen Germany Orion Pharma, Espoo, Finland This manuscript, developed by a group of chronic pain researchers and clinicians from around the world, aims to address the state of knowledge about fibromyalgia (FM) and identify ongoing challenges in the field of FM and other chronic pain syndromes that may be characterized by pain centralization/amplification/hypersensitivity. There have been many exciting developments in research studies of the pathophysiology and treatment of FM and related syndromes that have the potential to improve the recognition and management of patients with FM and other conditions with FM-like pain. However, much of the new information has not reached all clinicians, especially primary care clinicians, who have the greatest potential to use this new knowledge to positively impact their patients' lives. Furthermore, there are persistent misconceptions about FM and a lack of consensus regarding the diagnosis and treatment of FM. This paper presents a framework for future global efforts to improve the understanding and treatment of FM and other associated chronic pain syndromes, disseminate research findings, identify ways to enhance advocacy for these patients, and improve global efforts to collaborate and reach consensus about key issues related to FM and chronic pain in general. Univ Cincinnati, Coll Med, Dept Psychiat & Behav Neurosci, Cincinnati, OH USA Cardiff Inst Infect & Immun, Cardiff, S Glam, Wales Univ Michigan, Ann Arbor, MI 48109 USA Tufts Univ, Sch Med, Boston, MA 02111 USA Univ Fed Sao Paulo, Sao Paulo, Brazil Aarhus Univ, Danish Pain Res Ctr, Aarhus, Denmark Hyogo Coll Med, Nishinomiya, Hyogo, Japan Aichi Med Univ, Multidisciplinary Pain Ctr, Nagakute, Aichi, Japan Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA China Japan Friendship Hosp, Beijing, Peoples R China Univ Fed Sao Paulo, EPM, Sao Paulo, Brazil Web of Science
- Published
- 2016
28. Investigators at Department of Pharmacy Report Findings in Herbal Medicine [Antimicrobial Effects of Chemical Compounds Isolated Traditional Chinese Herbal Medicine (Tchm) Against Drug-resistant Bacteria: a Review Paper]
- Subjects
Traditional Chinese medicine -- Methods -- Patient outcomes ,Communicable diseases -- Care and treatment ,Obesity ,Bacterial infections ,Bacteria ,Alternative medicine ,Antibacterial agents ,Novels ,Editors ,Herbal medicine ,Pharmacy ,Physical fitness ,Microbial drug resistance ,Infection ,Drug resistance ,Drug discovery ,Drugs ,Health - Abstract
2019 MAR 9 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Complementary and Alternative Medicine - Herbal Medicine. [...]
- Published
- 2019
29. Biosimilars: a position paper of the European Society for Medical Oncology, with particular reference to oncology prescribers
- Author
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Tabernero, Josep, Vyas, Malvika, Giuliani, Rosa, Arnold, Dirk, Cardoso, Fatima, Casali, Paolo G., Cervantes, Andrés, Eggermont, Alexander, Eniu, Alexandru, Jassem, Jacek, Pentheroudakis, George, Peters, Solange, Rauh, Stefan, Zielinski, Christoph C., Stahel, Rolf A., Voest, Emile, Douillard, Jean-Yves, McGregor, Keith, Ciardiello, Fortunato, Universitat Autònoma de Barcelona, Tabernero, Josep, Vyas, Malvika, Giuliani, Rosa, Arnold, Dirk, Cardoso, Fatima, Casali, Paolo G, Cervantes, Andre, Eggermont, Alexander Mm, Eniu, Alexandru, Jassem, Jacek, Pentheroudakis, George, Peters, Solange, Rauh, Stefan, Zielinski, Christoph C, Stahel, Rolf A, Voest, Emile, Douillard, Jean-Yve, Mcgregor, Keith, Ciardiello, Fortunato, and University of Zurich
- Subjects
Oncology ,Cancer Research ,medicine.medical_specialty ,Alternative medicine ,Cancer Treatment ,610 Medicine & health ,Review ,Interchangeability ,Generic ,Breast cancer ,Internal medicine ,Health care ,Generics ,Biobetters ,Medicine ,1306 Cancer Research ,Health Financial Burden ,Biosimilars ,Potential impact ,business.industry ,Biosimilar ,Biobetter ,Medicamentos Biossimilares ,Neoplasias ,Non-comparable Biosimilars ,Editorial ,10032 Clinic for Oncology and Hematology ,Financial sustainability ,Position paper ,2730 Oncology ,Lung cancer ,business ,Healthcare system - Abstract
Biosimilars present a necessary and timely opportunity for physicians, patients and healthcare systems. If suitably developed clinically, manufactured to the correct standards and used appropriately, they can positively impact on the financial sustainability of healthcare systems. A critical consideration regarding the introduction of biosimilars into the clinic centres on the required information concerning all the respective procedures. This position paper aims to describe the issues revolving around biosimilars that are relevant to the field of oncology, especially the prescribers. More specifically, we discuss aspects related to definition, forms of biosimilars, labelling, extrapolation, interchangeability, switching, automatic substitution, clinical standards on safety and efficacy, responsibilities among prescribers and pharmacists, potential impact on financial burden in healthcare and the current scenario and future prospects of biosimilars in Europe and the rest of the world.
- Published
- 2017
30. Minimum standards on prevention, diagnosis and treatment of occupational and work-related skin diseases in Europe - position paper of the COST Action StanDerm (TD 1206)
- Author
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D. Mijakoski, Wolfgang Uter, Marija Bubaš, Anders Boman, M. N. Crepy, Vera Mahler, Lynda Bensefa-Colas, Mark Wilkinson, Jelena Macan, J. M. Ramada Rodilla, Margarida Gonçalo, S.M. John, Ana Giménez-Arnau, Andreas Bauer, Thomas Rustemeyer, Philipp Spring, L. Constandt, Jose Hernán Alfonso, AII - Inflammatory diseases, and Dermatology
- Subjects
medicine.medical_specialty ,Alternative medicine ,MEDLINE ,Legislation ,Dermatology ,Disease ,Skin Diseases ,Work related ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Malalties professionals ,medicine ,Humans ,Intensive care medicine ,business.industry ,medicine.disease ,030210 environmental & occupational health ,Pell -- Malalties ,Europe ,Occupational Diseases ,Infectious Diseases ,Practice Guidelines as Topic ,Position paper ,occupational hand eczema, occupational skin cancer, prevention, standards ,Skin cancer ,business ,Tertiary Prevention - Abstract
Background Skin diseases constitute up to 40% of all notified occupational diseases in most European countries, predominantly comprising contact dermatitis, contact urticaria, and skin cancer. While insufficient prevention of work-related skin diseases (WRSD) is a top-priority problem in Europe, common standards for prevention of these conditions are lacking. Objective To develop common European standards on prevention and management of WRSD and occupational skin diseases (OSD). Method Consensus amongst experts within occupational dermatology was achieved with regard to the definition of minimum evidence-based standards on prevention and management of WRSD/OSD. Results By definition, WRSDs/OSDs are (partially or fully) caused by occupational exposure. The definition of OSD sensu stricto additionally includes diverging national legal requirements, with an impact on registration, prevention, management, and compensation. With the implementation of the classification of WRSD/OSD in the International Classification of Diseases (ICD) 11th Revision in future, a valid surveillance and comparability across countries will be possible. Currently, WRDS and OSD are still under-reported. Depending on legislation and regulations, huge differences exist in notification procedures in Europe, although notification is crucial to prevent chronic and relapsing disease. Facilities for early diagnosis, essential for individual patient management, should be based on existing guidelines and include a multidisciplinary approach. Patch testing is essential if contact dermatitis persists or relapses. Workplace exposure assessment of WRSD/OSD requires full labelling of product ingredients on material safety data sheets helping to identify allergens, irritants and skin carcinogens. Comparable standards in primary, secondary and tertiary prevention must be established in Europe to reduce the burden of WRSD/OSD in Europe. Conclusion The adoption of common European standards on prevention of WRSD/OSD will contribute to reduce the incidence of OSD and their socio-economic burden.
- Published
- 2017
31. Treating Psoriasis and Psoriatic Arthritis: Position Paper on Applying the Treat-to-target Concept to Canadian Daily Practice
- Author
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Michel Zummer, Wayne Gulliver, Jensen Yeung, Vinod Chandran, Dafna D. Gladman, Kirk Barber, Sherry Rohekar, Karen Adams, Yves Poulin, Kim A. Papp, Vincent C. Ho, Chih-Ho Hong, Melinda Gooderham, Majed Khraishi, Anthony S. Russell, Jan Dutz, Olga Ziouzina, Snezana Barac, Cheryl F. Rosen, Proton Rahman, Jacob Karsh, Cathy Flanagan, Marc Bourcier, Charles Lynde, and Ronald Vender
- Subjects
medicine.medical_specialty ,Canada ,Immunology ,Alternative medicine ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Psoriatic arthritis ,0302 clinical medicine ,Rheumatology ,Psoriasis ,Daily practice ,medicine ,Immunology and Allergy ,Humans ,Quality of Health Care ,030203 arthritis & rheumatology ,business.industry ,Arthritis, Psoriatic ,Disease Management ,medicine.disease ,Clinical trial ,Needs assessment ,Physical therapy ,Position paper ,Observational study ,business - Abstract
Objective.To develop preliminary treat-to-target (T2T) recommendations for psoriasis and psoriatic arthritis (PsA) for Canadian daily practice.Methods.A task force composed of expert Canadian dermatologists and rheumatologists performed a needs assessment among Canadian clinicians treating these diseases as well as an extensive literature search on the outcome measures used in clinical trials and practice.Results.Based on results from the needs assessment and literature search, the task force established 5 overarching principles and developed 8 preliminary T2T recommendations.Conclusion.The proposed recommendations should improve management of psoriasis and PsA in Canadian daily practice. However, these recommendations must be further validated in a real-world observational study to ensure that their use leads to better longterm outcomes.
- Published
- 2017
32. The polypill in cardiovascular prevention: evidence, limitations and perspective - position paper of the European Society of Hypertension
- Author
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Giuseppe Mancia, A. Coca, Renata Cifkova, Enrico Agabiti-Rosei, Josep Redon, and Athanasios J. Manolis
- Subjects
medicine.medical_specialty ,Physiology ,Drug Compounding ,Alternative medicine ,Disease ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Cardiovascular prevention ,Internal Medicine ,Medicine ,Humans ,Hypoglycemic Agents ,030212 general & internal medicine ,Intensive care medicine ,Polypill ,Antihypertensive Agents ,Societies, Medical ,business.industry ,Standard treatment ,Perspective (graphical) ,Europe ,Drug Combinations ,Cardiovascular Diseases ,Position paper ,Lipid lowering ,Hydroxymethylglutaryl-CoA Reductase Inhibitors ,Cardiology and Cardiovascular Medicine ,business ,Platelet Aggregation Inhibitors - Abstract
Antihypertensive, lipid lowering, antidiabetic and antiplatelet treatments all substantially reduce the risk of cardiovascular morbid and fatal events. In real life, however, effective implementation of these treatments is rare, and thus their contribution to cardiovascular prevention is much less than it could be, based on research data. This article reviews the pros and cons of cardiovascular prevention by the polypill approach. It is argued that the high prevalence of individuals with a multifactorial risk profile provides a strong rationale for a therapeutic strategy based on the combination in a single tablet of drugs against different risk factors. It is further argued that other important favourable arguments exist. First, in real-life adherence to all above treatments is very low, leading to a major increase in the incidence and risk of cardiovascular outcomes. Second, although a large number of factors are involved, adherence is adversely affected by the complexity of the prescribed treatment regimen and can be considerably improved by treatment simplification. Third, recent studies in patients with a history of manifest cardiovascular disease have documented that different cardiovascular drugs can be combined in a single tablet with no loss of their individual efficacy or unexpected inconveniences and this does favour adherence to treatment and multiple risk factor control, supporting use of the polypill in secondary cardiovascular prevention. It is finally also mentioned, however, that the polypill may have some drawbacks and that at present no evidence is available that this approach reduces cardiovascular outcome to a greater degree than standard treatment strategies. Trials are under way to provide an answer to this question and thus allow the therapeutic value of this approach to be known.
- Published
- 2017
33. Quality of life measurement in atopic dermatitis. Position paper of the European Academy of Dermatology and Venereology (EADV) task force on quality of life
- Author
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A.P. Oranje, Mir-saeed Salek, Pavel V Chernyshov, Françoise Poot, L. Manolache, Servando E Marron, Andrew Yule Finlay, and Lucia Tomas-Aragones
- Subjects
medicine.medical_specialty ,Venereology ,Alternative medicine ,Expert analysis ,Dermatology ,Severity of Illness Index ,Dermatitis, Atopic ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Surveys and Questionnaires ,medicine ,Humans ,030212 general & internal medicine ,Task force ,business.industry ,Age Factors ,Reproducibility of Results ,Atopic dermatitis ,medicine.disease ,humanities ,Infectious Diseases ,Atopic dermatitis (eczema) ,Quality of Life ,Position paper ,business - Abstract
There is a need for researchers to have easy reference to the wide spectrum of different types of quality of life (QoL) instruments that can be used in atopic dermatitis (AD). Previous reviews on QoL in AD do not cover the full spectrum of QoL measures used in studies on AD. This study, on behalf of the European Academy of Dermatology and Venereology (EADV) Task Force on QoL, contains information on instruments available for health-related QoL and family QoL assessment in AD including information on validation, experience of QoL assessment in AD for different purposes, peculiarities of QoL assessment in different age groups, expert analysis of available instruments including data on limitations of their use and recommendations of the Task Force.
- Published
- 2017
34. The continuum of personalized cardiovascular medicine: a position paper of the European Society of Cardiology
- Author
-
Kirchhof, Paulus, Sipido, Karin R., Cowie, Martin R., Eschenhagen, Thomas, Fox, Keith A.A., Katus, Hugo, Schroeder, Stefan, Schunkert, Heribert, Priori, Silvia, Alonso, Angeles, Chezaubernard, Claire, Doevendans, Pieter, Fox, Keith, Khder, Yasser, Kramer, Frank, Kristensen, Steen, Maitland-Van der Zee, Anke-Hilse, Oertelt-Prigione, Sabine, Pinto, Fausto, Pocock, Stuart, Priori, Silvia G., Sartorius, Alfonso, Schott, Daniela, Schwab, Matthias, Sipido, Karin, Svensson, Anders, Swedberg, Karl, Wallentin, Lars, Weimers, Marianne, Herttuala, Seppo Yla, and Pulmonology
- Subjects
Diagnostic Imaging ,medicine.medical_specialty ,Population ,Alternative medicine ,Risk Assessment ,Internal medicine ,Patient-Centered Care ,medicine ,Humans ,Precision Medicine ,education ,education.field_of_study ,Clinical Trials as Topic ,Evidence-Based Medicine ,business.industry ,Evidence-based medicine ,Genomics ,Precision medicine ,3. Good health ,Current Opinion ,Cardiovascular Diseases ,Needs assessment ,Cardiology ,Position paper ,Personalized medicine ,Diffusion of Innovation ,Cardiology and Cardiovascular Medicine ,Risk assessment ,business ,Biomarkers ,Needs Assessment - Abstract
There is strong need to develop the current stratified practice of CVD management into a better personalized cardiovascular medicine, within a broad framework of global patient care. Clinical information obtained from history and physical examination, functional and imaging studies, biochemical biomarkers, genetic/epigenetic data, and pathophysiological insights into disease-driving processes need to be integrated into a new taxonomy of CVDs to allow personalized disease management. This has the potential for major health benefits for the population suffering from cardiovascular diseases.
- Published
- 2014
35. Sexual and Reproductive Health Care: A Position Paper of the Society for Adolescent Health and Medicine
- Author
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Arik V. Marcell, Erica J. Gibson, Pamela J. Burke, Kim Urbach, Mandy S. Coles, Giuseppina Di Meglio, May Lau, Sara M. Handschin, and Kathleen P. Tebb
- Subjects
medicine.medical_specialty ,Adolescent ,Reproductive health care ,business.industry ,Public Health, Environmental and Occupational Health ,Alternative medicine ,Organizational Policy ,United States ,Psychiatry and Mental health ,Reproductive Health ,Adolescent Medicine ,Adolescent Health Services ,Family medicine ,Pediatrics, Perinatology and Child Health ,Health care ,medicine ,Humans ,Position paper ,Health education ,business ,Societies, Medical ,Reproductive health ,Adolescent health - Published
- 2014
36. ASH Position Paper: Evaluation and Treatment of Orthostatic Hypotension
- Author
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Cyndya A. Shibao, Italo Biaggioni, and Lewis A. Lipsitz
- Subjects
Review Paper ,medicine.medical_specialty ,business.industry ,Hospitalized patients ,Endocrinology, Diabetes and Metabolism ,Treatment outcome ,Alternative medicine ,Blood Pressure ,Syncope ,Hypotension, Orthostatic ,Orthostatic vital signs ,Treatment Outcome ,Blood pressure ,Risk Factors ,Hypertension ,Practice Guidelines as Topic ,Internal Medicine ,Physical therapy ,Humans ,Medicine ,Position paper ,Cardiology and Cardiovascular Medicine ,business ,Intensive care medicine ,Stepwise approach - Abstract
This paper provides recommendations on the treatment of orthostatic hypotension (OH) as reviewed by the American Society of Hypertension. It focuses on recent reports on the evaluation and management of OH and provides practical advice for clinicians on how to screen, diagnose, and treat patients using behavioral, nonpharmacologic, and pharmacologic strategies. The authors also provide a stepwise approach on how to apply new findings to successfully control OH and reduce the risk of syncope and falls in these patients. Treatment of OH is also discussed in special situations such as in hypertensive and hospitalized patients. It should be noted, however, that research in this area is mostly limited to studies in small numbers of patients. Unfortunately, the trials of the type needed to develop evidence‐based guidelines are not available for this condition.
- Published
- 2013
37. Medical papers related to keywords of vaccine and vaccination in KoreaMed database, Korea (1962-2012)
- Author
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Chong-Woo Bae, Hee Young Ju, Kyung Suk Lee, Myung Hee Han, Sung-Ho Cha, and Young-jin Lee
- Subjects
Pharmacology ,medicine.medical_specialty ,Vaccines ,PubMed ,Future studies ,business.industry ,Vaccination ,Public Health, Environmental and Occupational Health ,Alternative medicine ,MEDLINE ,Medline ,KoreaMed ,Medical papers ,Infectious Diseases ,Family medicine ,medicine ,Immunology and Allergy ,Original Article ,Journals ,sense organs ,business ,human activities - Abstract
Purpose To describe the present status and changing patterns of medical papers related to keywords of vaccine and vaccination published in Korea over the last 50 years, and provide basic data for future studies. Materials and Methods 185,603 papers are registered in the medical database KoreaMed, which is run by Korean Association of Medical Journal Editors. Among these papers, a search with the keywords vaccine or vaccination revealed a total of 1,089 articles which were published on vaccine and/or vaccination during the period of September 2, 1962 to April 30, 2012. Our study endeavors to analyze these 1,089 articles. Results Only one article published with the keywords vaccine and/or vaccination was published in the 1960s, and the number of journals steadily increased starting from the 1970s (24 articles) to 2 times, 10 times, 20 times in the 1980s, 1990s, and the 2000s (585 articles), respectively. The articles were classified into reviews (20.2%), original articles with clinical study (40.7%), original articles with experimental study (24.6%), and case reports (8.2%). The review articles mainly dealt with an overview. The original articles with clinical study were on epidemiology, effect and immunogenicity, clinical trial. Original articles with experimental study were mainly comprised of complication and overview. Articles on vaccine, pathogen or disease topics were mostly microorganisms such as bacteria or viruses, and studies on anti-cancer vaccines or vaccines of specific diseases were sparse. Conclusion The above data reflects the clinical uses of vaccines in Korea and the history of vaccine studies. The number of vaccine-related articles is increasing rapidly since the first article was published in 1962. This implies that with the increase of studies of clinical trials, clinical uses and results and analyses of the results, articles relating to basic studies are also on the rise. We intend these findings to be of use to researchers in this active and expanding field.
- Published
- 2012
38. Childhood immunization, homoeopathy and community nurses. -Earlier version of this paper presented at the National Immunisation Conference (3rd: 1993: Melbourne )
- Author
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Roden, Janet
- Published
- 1994
39. Evidence or Evidence Based Practice? An Analysis of IASL Research Forum Papers, 1998-2009
- Author
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Marcia A. Mardis
- Subjects
Program evaluation ,medicine.medical_specialty ,Medical education ,Evidence-based practice ,media_common.quotation_subject ,Professional development ,Alternative medicine ,Library science ,school librarianship ,School library ,Library and Information Sciences ,lcsh:Z ,lcsh:Bibliography. Library science. Information resources ,scholarly research ,Presentation ,Empirical research ,medicine ,conference papers ,Sociology ,Research evidence ,media_common - Abstract
Objective - Conferences are essential opportunities for professional development and for learning about research. This study analyses papers presented in the Research Forum track of the International Association of School Librarians (IASL) conferences to determine whether the amount of school library research reporting increased or decreased over time; who (i.e., what author roles and affiliations) has written about research; which countries were represented in the research articles; what topics were discussed in research articles; and what research methodologies were used. The aim was to determine the extent to which the Research Forum provides research evidence that relates to practice. Methods - This study continues the longitudinal analysis of published school library research begun by Clyde (1996) by analyzing Research Forum papers published in IASL conference proceedings from 1998-2009 and using the same approaches and metrics as previous studies by Clyde (e.g., 1996; 2002; 2004), Clyde and Oberg (2004), and Oberg (2006). Results - Conference paper topics, author origins, quantities, and research approaches remained static through the 11 years analyzed. The analysis reveals that the papers’ authors, methods, and topics reflected those found in previous studies of school library research. As well as replicating previous studies, the role of academic research at a practitioner-based conference was investigated. Conclusions - Based on long-established imperatives from leaders in the profession, the IASL conferences provide both evidence and evidence -based practice for school librarians from all over the world. However, when scholarly research is shared at practitioner venues, it is possible that school librarians may assume that research results constitute evidence -based practice (EBP), not evidence upon which practice should be based. This distinction is important if considering that the purpose of academic research is to objectively inform, not to advocate a particular position or practice. The Research Forum can be a valuable venue for the presentation of empirical research findings and conclusions and objective program evaluations and provide a valuable complement to the evidence -based practice descriptions shared in the Professional Papers portion of the conference program. It is argued that the Research Forum must be clear in its purpose: to present the results of research; to present effective practice determined by rigorous evaluation; or to present research-supported arguments for the support of school libraries. Through a reconceptualization of EBP, the paper demonstrates how EBP is both a method and a methodology for the presentation of school library research and practice in a conference atmosphere.
- Published
- 2011
40. The Second SAGES/ASGE White Paper on natural orifice transluminal endoscopic surgery: 5 years of progress
- Author
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Robert H. Hawes, David W. Rattner, Lee L. Swanstrom, Michael L. Kochman, and Steven D. Schwaitzberg
- Subjects
Medical education ,medicine.medical_specialty ,business.industry ,Alternative medicine ,Natural Orifice Endoscopic Surgery ,Natural orifice transluminal endoscopic surgery ,Outcome assessment ,Surgery ,White paper ,Harm ,medicine ,business ,Gastrointestinal endoscopy - Abstract
) was first introduced,many physicians could envisage its potential as a lessinvasive and more cosmetic way to perform surgery. Thepotential for harm if NOTES was adopted too rapidlywas also readily apparent. To ensure the responsibledevelopment of these technologies and techniques and toencourage accurate and honest outcome assessment inhumans, the Society of American Gastrointestinal andEndoscopic Surgeons (SAGES) and the American Soci-ety for Gastrointestinal Endoscopy (ASGE) assembled aJoint Committee to serve as a working group to reviewthe issues involving NOTES. This working group sub-sequently published the ASGE/SAGES Working Groupon Natural Orifice Translumenal Endoscopic SurgeryWhite Paper [1, 2], which laid out the fundamentalchallenges to be addressed and outlined a pathwayfor the responsible development and evaluation ofNOTES. As part of this mission, the Joint Committeealso created an organization called Natural OrificeSurgery Consortium for Assessment and Research(NOSCAR). NOSCAR organized international meetings,developed and sought funding for a research agenda,fostered the translation of research findings into clinicaltrials, and began development of a human registry totrack the clinical adoption of NOTES.Summary of progress on issues outlinedby the original White PaperNOSCAR continues to be the primary vehicle foraddressing the issues laid out in the original White Paper(Table 1). By focusing research efforts on critical topicsand by revisiting the issues frequently (primarily by peerreview and at the annual meeting), substantial progress hasbeen achieved in addressing many of the challengesinherent in natural orifice surgery.
- Published
- 2011
41. Series: Pragmatic trials and real world evidence: Paper 3. Patient selection challenges and consequences
- Author
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Diederick E. Grobbee, Antonio Ciaglia, Alison Lightbourne, Elaine A. Irving, Rolf H.H. Groenwold, Katrien Oude Rengerink, Laurent Eckert, Susan Collier, Sally Worsley, and Shona Kalkman
- Subjects
medicine.medical_specialty ,Epidemiology ,Alternative medicine ,Sample (statistics) ,Target population ,Real world evidence ,Pragmatic trial ,03 medical and health sciences ,0302 clinical medicine ,Enrollment ,Pragmatic Clinical Trials as Topic ,Journal Article ,Humans ,Medicine ,Generalizability theory ,030212 general & internal medicine ,Intensive care medicine ,Selection (genetic algorithm) ,Representativeness ,Real-world evidence ,business.industry ,Patient Selection ,Participant ,Recruitment ,business ,Research setting ,030217 neurology & neurosurgery - Abstract
This paper addresses challenges of identifying, enrolling and retaining participants in a in a trial conducted within a routine care setting. All patients that are potential candidates for the treatments in routine clinical practice should be considered eligible for a pragmatic trial. To ensure generalizability, the recruited sample should have a similar distribution of the treatment effect modifiers as the target population. In practice this can be best achieved by including - within the selected sites - all patients without further selection. If relevant heterogeneity between subgroups is expected, increasing the relative proportion of the subgroup of patients in the heterogeneous trial could be considered (oversampling), or a separate trial in this subgroup can be planned. Selection will nevertheless occur. Low enrolment and loss to follow-up can introduce selection and can jeopardize validity as well as generalizability. Pragmatic trials are conducted in clinical practice rather than in a dedicated research setting, which could reduce recruitment rates. However, if a trial poses a minimal burden to the physician and the patient, and routine clinical practice is maximally adhered to, the participation rate may be high and loss to follow-up will not be a specific problem for pragmatic trials.
- Published
- 2017
42. NGNA: Position Paper on essential gerontological nursing education in registered nursing and continuing education programs
- Author
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Amy Cotton, Linda Hassler, Jane Nunnelee, Joanne Alderman, Susan Schumacher, Deborah Marks Conley, Elizabeth Ibby Tanner, and Melodee Harris
- Subjects
medicine.medical_specialty ,Education, Continuing ,business.industry ,Alternative medicine ,Gerontological nursing ,Continuing education ,Education, Nursing, Baccalaureate ,Geriatric Nursing ,Nursing ,Workforce ,medicine ,Humans ,Position paper ,Students, Nursing ,Curriculum ,Nurse education ,business ,Gerontology - Published
- 2015
43. Opioids for chronic noncancer pain: A position paper of the American Academy of Neurology
- Author
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J. A. Katz, M. A. Swerdloff, S. D. Brass, C. E. Argoff, J. Markman, M. Backonja, N. Katz, and G. M. Franklin
- Subjects
medicine.medical_specialty ,business.industry ,Addiction ,media_common.quotation_subject ,Public health ,Alternative medicine ,Chronic pain ,medicine.disease ,Analgesics, Opioid ,Patient safety ,Universal precautions ,Anesthesia ,Emergency medicine ,Animals ,Humans ,Pain Management ,Medicine ,Position paper ,Neurology (clinical) ,Chronic Pain ,Medical prescription ,business ,media_common - Abstract
The Patient Safety Subcommittee requested a review of the science and policy issues regarding the rapidly emerging public health epidemic of prescription opioid-related morbidity and mortality in the United States. Over 100,000 persons have died, directly or indirectly, from prescribed opioids in the United States since policies changed in the late 1990s. In the highest-risk group (age 35–54 years), these deaths have exceeded mortality from both firearms and motor vehicle accidents. Whereas there is evidence for significant short-term pain relief, there is no substantial evidence for maintenance of pain relief or improved function over long periods of time without incurring serious risk of overdose, dependence, or addiction. The objectives of the article are to review the following: (1) the key initiating causes of the epidemic; (2) the evidence for safety and effectiveness of opioids for chronic pain; (3) federal and state policy responses; and (4) recommendations for neurologists in practice to increase use of best practices/universal precautions most likely to improve effective and safe use of opioids and to reduce the likelihood of severe adverse and overdose events. Neurology® 2014;83:1277–1284
- Published
- 2015
44. Transitioning from a Paper-based to an Electronic Version of the Journal of Insurance Medicine
- Author
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Ross MacKenzie
- Subjects
medicine.medical_specialty ,business.industry ,Family medicine ,Insurance medicine ,Alternative medicine ,medicine ,MEDLINE ,General Medicine ,Paper based ,business - Published
- 2015
45. An ESC position paper on cardio-oncology
- Author
-
José Luis Zamorano
- Subjects
medicine.medical_specialty ,Pathology ,Cardiology ,Alternative medicine ,Improved survival ,030204 cardiovascular system & hematology ,Medical Oncology ,Malignancy ,Core curriculum ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Neoplasms ,medicine ,Humans ,030212 general & internal medicine ,Cardio oncology ,Intensive care medicine ,Patient Care Team ,Cardiotoxicity ,business.industry ,Cancer ,medicine.disease ,Position paper ,Cardiology and Cardiovascular Medicine ,business - Abstract
Jose Zamorano discusses the need for and what cardiology can expect in the ESC position paper One of the changes that we have recently seen in the European Society of Cardiology (ESC) Core Curriculum, is the presence of a chapter entitled Cardio Oncology. Such topic has also been considered for an ESC Committee of Practice Guidelines position paper. We may wonder about the need for such a new topic. There is no doubt however that malignancy is a worldwide health and social problem. Advances in treatment have led to improved survival of cancer patients, but morbidity and mortality has also increased due to the side effects of treatment. This means that as survival rates in cancer patients improve, there is an increased interest in preventing or treating potential complications related to cancer therapies. If we look to the major potential side effects of anticancer drugs, cardiovascular diseases (CVD) are one of the most frequent complications that may lead to abandoning of the treatment. We need to differentiate cardiotoxicity (direct effects of the cancer treatment) to the new appearance of CVD due to accelerated development of CVD in …
- Published
- 2016
46. AB020. To produce a white paper on: ‘how to develop the perfect real-time, real-world effectiveness and cost-effectiveness trial’
- Author
-
Jacqueline Brereton
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Pediatrics ,integumentary system ,business.industry ,Cost effectiveness ,Alternative medicine ,030204 cardiovascular system & hematology ,medicine.disease ,3. Good health ,law.invention ,03 medical and health sciences ,Patient safety ,0302 clinical medicine ,White paper ,Randomized controlled trial ,law ,030220 oncology & carcinogenesis ,Health care ,Medicine ,Medical emergency ,Session 2.1: Pragmatic Approaches ,business ,Adverse effect ,Asthma - Abstract
Background The Salford Lung Study (SLS) involves two prospective patient cohorts—one patients with asthma; the other patients with COPD. SLS is believed to be the first pre-license, prospective randomised controlled trial (RCT) to use electronic healthcare records to monitor patient safety. Safety events are processed in near real-time, and a linked database system creates daily summaries that alert a specialist safety team to potential treatment-related adverse events. SLS is a ‘world first’ in effectiveness research. To synthesise the learnings from the SLS and experiences from leading experts in real-world research in a White Paper to help guide the future design and feasibility of pragmatic RCTs.
- Published
- 2016
47. Stemming the Escalating Cost of Prescription Drugs: A Position Paper of the American College of Physicians
- Author
-
Hilary Daniel
- Subjects
medicine.medical_specialty ,Drug marketing ,business.industry ,010102 general mathematics ,Comparative effectiveness research ,Alternative medicine ,Public policy ,General Medicine ,01 natural sciences ,03 medical and health sciences ,0302 clinical medicine ,Pharmacotherapy ,Family medicine ,Internal Medicine ,Medicine ,Position paper ,030212 general & internal medicine ,0101 mathematics ,Medical prescription ,business ,Developed country ,health care economics and organizations - Abstract
This American College of Physicians position paper, initiated and written by its Health and Public Policy Committee and approved by the Board of Regents on 16 February 2016, reports policy recommendations from the American College of Physicians to address the escalating costs of prescription drugs in the United States. Prescription drugs play an important part in treating and preventing disease. However, the United States often pays more for some prescription drugs than other developed countries, and the high price and increasing costs associated with prescription medication is a major concern for patients, physicians, and payers. Pharmaceutical companies have considerable flexibility in how they price drugs, and the costs that payers and patients see are dependent on how payers are able to negotiate discounts or rebates. Beyond setting list prices are issues of regulatory approval, patents and intellectual property, assessment of value and cost-effectiveness, and health plan drug benefits. These issues are linked, and comprehensive efforts will be needed to affect how drugs are priced in the United States.
- Published
- 2016
48. Benefits and harm of systemic steroids for short- And long-term use in rhinitis and rhinosinusitis: An EAACI position paper
- Subjects
medical literature ,evidence based medicine ,Rhinosinusitis ,adverse event ,gastrointestinal symptom ,otorhinolaryngology ,eye disease ,nose polyp ,mental disease ,systemic therapy ,cardiovascular disease ,lipid metabolism ,Cushingoid syndrome ,Rhinitis ,acute rhinosinusitis ,alternative medicine ,drug effect ,immunosuppressive treatment ,nose disease ,Glucocorticosteroids ,risk benefit analysis ,priority journal ,protein metabolism ,diabetes mellitus ,drug induced disease ,endocrine disease ,pediatric patient ,hypothalamus hypophysis adrenal system ,injection site discomfort ,drug cost ,desensitization ,review ,autoimmune disease ,fungal sinusitis ,drug activity ,rhinitis ,short course therapy ,drug mechanism ,carbohydrate metabolism ,human ,avascular necrosis ,peptic ulcer ,drug use ,long term care ,allergic rhinitis ,calcium balance ,hypophysis disease ,chronic rhinosinusitis ,antiinflammatory activity ,asthma ,osteoporosis ,infection ,drug efficacy ,hypothalamus disease ,upper respiratory tract infection ,occupational disease ,glucocorticoid ,hyperglycemia - Abstract
Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that - potentially severe - side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.
- Published
- 2020
49. Position paper on mesotherapy
- Author
-
Vijay K Garg, Venkataram Mysore, and Rashmi Sarkar
- Subjects
medicine.medical_specialty ,business.industry ,Injections, Subcutaneous ,Lipolysis ,Alternative medicine ,rejuvenation ,Cosmetic Techniques ,Dermatology ,lcsh:RL1-803 ,Skin Diseases ,Surgery ,Scientific evidence ,Mesotherapy ,Infectious Diseases ,mesotherapy ,medicine ,lcsh:Dermatology ,Humans ,Position paper ,Intensive care medicine ,business - Abstract
Mesotherapy is a controversial cosmetic procedure which has received publicity among the lay people, in the internet and in the media. It refers to minimally invasive techniques which consist of the use of intra- or subcutaneous injections containing liquid mixture of compounds (pharmaceutical and homeopathic medications, plant extracts, vitamins and other ingredients) to treat local medical and cosmetic conditions. This position paper has examined the available evidence and finds that acceptable scientific evidence for its effectiveness and safety is lacking. IADVL taskforce, therefore would like to state that the use of this technique remains controversial at present. Further research and well-designed controlled scientific studies are required to substantiate the claims of benefit of this mode of therapy.
- Published
- 2011
50. Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper
- Author
-
Evelijn Lourijsen, Mika J. Mäkelä, Ludger Klimek, Ralph Mösges, Wytske Fokkens, Sanna Toppila-Salmi, Valérie Hox, Kristian Aasbjerg, Thibaut Van Zele, Philippe Gevaert, Claus Bachert, Joaquim Mullol, Koen Boussery, Arnout Jordens, Sophie Scheire, Paloma Campo, P. V. Tomazic, Laura Pujols, Martin Wagemann, Ioana Agache, Isam Alobid, Job F M van Boven, Michael Rudenko, Carmen Rondon, Claire Hopkins, Glenis Scadding, Peter Hellings, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, and UCL - (SLuc) Service d'oto-rhino-laryngologie
- Subjects
Rhinology ,medical literature ,evidence based medicine ,Rhinosinusitis ,adverse event ,gastrointestinal symptom ,otorhinolaryngology ,eye disease ,nose polyp ,Systemic therapy ,mental disease ,systemic therapy ,DOUBLE-BLIND ,0302 clinical medicine ,cardiovascular disease ,ORAL STEROIDS ,lipid metabolism ,Medicine and Health Sciences ,SEVERE NASAL POLYPOSIS ,Cushingoid syndrome ,Immunology and Allergy ,030223 otorhinolaryngology ,Rinitis ,Rhinitis ,acute rhinosinusitis ,alternative medicine ,drug effect ,CORTICOSTEROID-THERAPY ,immunosuppressive treatment ,nose disease ,Glucocorticosteroids ,risk benefit analysis ,3. Good health ,ALLERGIC RHINITIS ,priority journal ,protein metabolism ,SEASONAL ,diabetes mellitus ,drug induced disease ,endocrine disease ,BONE-MINERAL DENSITY ,ENDOSCOPIC SINUS SURGERY ,pediatric patient ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,hypothalamus hypophysis adrenal system ,injection site discomfort ,Immunology ,drug cost ,desensitization ,review ,autoimmune disease ,fungal sinusitis ,03 medical and health sciences ,WEGENERS-GRANULOMATOSIS ,drug activity ,short course therapy ,medicine ,drug mechanism ,carbohydrate metabolism ,human ,Intensive care medicine ,Glucocorticoides ,Glucocorticoids ,avascular necrosis ,peptic ulcer ,Asthma ,drug use ,long term care ,allergic rhinitis ,calcium balance ,business.industry ,hypophysis disease ,chronic rhinosinusitis ,antiinflammatory activity ,Evidence-based medicine ,RC581-607 ,asthma ,medicine.disease ,osteoporosis ,infection ,Review article ,RHEUMATOID-ARTHRITIS ,drug efficacy ,Upper respiratory tract infection ,030228 respiratory system ,hypothalamus disease ,upper respiratory tract infection ,occupational disease ,glucocorticoid ,GLUCOCORTICOID-RECEPTOR-ALPHA ,hyperglycemia ,Immunologic diseases. Allergy ,Airway ,business ,Medical literature - Abstract
Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that-potentially severe-side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease. ispartof: CLINICAL AND TRANSLATIONAL ALLERGY vol:10 issue:1 ispartof: location:England status: published
- Published
- 2019
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