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Start Over Author "Luo, Jiani" Topic angiotensinii (angii)
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1. Fenofibrate ameliorates cardiac hypertrophy by activation of peroxisome proliferator-activated receptor-α partly via preventing p65-NFκB binding to NFATc4.

Author

Zou, Jian, Le, Kang, Xu, Suowen, Chen, Jianwen, Liu, Zhiping, Chao, Xiaojuan, Geng, Biao, Luo, Jiani, Zeng, Siyu, Ye, Jiantao, and Liu, Peiqing

Subjects
*FENOFIBRATE, *CARDIAC hypertrophy, *ENZYME activation, *PEROXISOME proliferator-activated receptors, *NF-kappa B, *BINDING sites, *BRAIN natriuretic factor
Abstract

Highlights: [•] Fenofibrate ameliorates cardiac hypertrophy in vivo and in vitro. [•] The interaction between p65-NFκB and NFATc4 regulates cardiac hypertrophy. [•] Fenofibrate attenuates cardiac hypertrophy via activating PPAR-α and thereby preventing the association of p65-NFκB with NFATc4. [Copyright &y& Elsevier]

Published
2013
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