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Your search keyword '"Avilés-Robles M"' showing total 2 results
Start Over Author "Avilés-Robles M" Topic antifungal agents
2 results on '"Avilés-Robles M"'

1. Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network.

Author

Bucayu RFT, Boge CLK, Yildirim I, Avilés-Robles M, Vora SB, Berman DM, Sharma TS, Sung L, Castagnola E, Palazzi DL, Danziger-Isakov L, Yin DE, Roilides E, Maron G, Tribble AC, Soler-Palacin P, López-Medina E, Romero J, Belani K, Arrieta AC, Carlesse F, Nolt D, Halasa N, Dulek D, Rajan S, Muller WJ, Ardura MI, Pong A, Gonzalez BE, Salvatore CM, Huppler AR, Aftandilian C, Abzug MJ, Chakrabarti A, Green M, Lutsar I, Knackstedt ED, Johnson SK, Steinbach WJ, Fisher BT, and Wattier RL

Subjects
Humans, Child, Female, Male, Child, Preschool, Adolescent, Infant, Administration, Intravenous, Triazoles therapeutic use, Triazoles administration & dosage, Cohort Studies, Treatment Outcome, Antifungal Agents therapeutic use, Antifungal Agents administration & dosage, Candidiasis, Invasive drug therapy
Abstract

Of 319 children with invasive candidiasis, 67 (21%) transitioned from intravenous to enteral antifungal therapy. Eight (12%) transitioned back to intravenous antifungal therapy, one due to perceived treatment failure defined by clinical progression or worsening. Global treatment response at study completion was successful in 66 participants who transitioned to enteral therapy., (© The Author(s) 2024. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)

Published
2024
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2. Disseminated penicilliosis due to Penicillium chrysogenum in a pediatric patient with Henoch-Schönlein syndrome.

Author

Avilés-Robles M, Gómez-Ponce C, Reséndiz-Sánchez J, Rodríguez-Tovar AV, Ceballos-Bocanegra A, and Martínez-Rivera Á

Subjects
Amphotericin B therapeutic use, Anti-Bacterial Agents therapeutic use, Caspofungin, Child, Echinocandins therapeutic use, Fever, Glomerulonephritis complications, Humans, Hyalohyphomycosis drug therapy, Hyalohyphomycosis microbiology, IgA Vasculitis complications, Immunocompromised Host, Kidney Failure, Chronic complications, Lipopeptides therapeutic use, Male, Penicillium chrysogenum drug effects, Spleen microbiology, Spleen pathology, Splenectomy, Tomography, X-Ray Computed, Treatment Outcome, Voriconazole therapeutic use, Antifungal Agents therapeutic use, Hyalohyphomycosis diagnostic imaging, Penicillium chrysogenum isolation & purification
Abstract

A case of disseminated infection caused by Penicillium chrysogenum in a 10-year-old boy with a history of Henoch-Schönlein purpura and proliferative glomerulonephritis, treated with immunosuppressors, is reported herein. The patient had a clinical picture of 2 weeks of fever that did not respond to treatment with broad-spectrum antibiotics and amphotericin B. Computed tomography imaging showed diffuse cotton-like infiltrates in the lungs, hepatomegaly, mesenteric lymphadenopathy, and multiple well-defined round hypodense lesions in the spleen. His treatment was changed to caspofungin, followed by voriconazole. One month later, a splenic biopsy revealed hyaline septate hyphae of >1μm in diameter. Fungal growth was negative. However, molecular analysis showed 99% identity with P. chrysogenum. A therapeutic splenectomy was performed, and treatment was changed to amphotericin B lipid complex and caspofungin. The patient completed 2 months of treatment with resolution of the infection. P. chrysogenum is a rare causative agent of invasive fungal infections in immunocompromised patients, and its diagnosis is necessary to initiate the appropriate antifungal treatment., (Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Published
2016
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