23 results on '"biva"'
Search Results
2. Athletic bioimpedance-based equations underestimate fat free mass components in male elite soccer players: development and validation of new soccer-specific predictive models
- Author
-
Francesco Campa, Tindaro Bongiovanni, Alessio Rossi, Giuseppe Cerullo, Andrea Casolo, Giulia Martera, Athos Trecroci, Tatiana Moro, and Antonio Paoli
- Subjects
Bioelectric impedance analysis ,BIA ,BIVA ,Body composition ,Lean soft tissue ,Somatotype ,Medicine - Abstract
Abstract Background Bioelectrical impedance analysis (BIA) is a rapid and user-friendly technique for assessing body composition in sports. Currently, no sport-specific predictive equations are available, and the utilization of generalized formulas can introduce systematic bias. The objectives of this study were as follows: (i) to develop and validate new predictive models for estimating fat-free mass (FFM) components in male elite soccer players; (ii) to evaluate the accuracy of existing predictive equations. Methods A total of 102 male elite soccer players (mean age 24.7 ± 5.7 years), participating in the Italian first league, underwent assessments during the first half of the in-season period and were randomly divided into development and validation groups. Bioelectrical resistance (R) and reactance (Xc), representing the bioimpedance components, were measured using a foot-to-hand BIA device at a single frequency of 50 kHz. Dual-energy X-ray absorptiometry was employed to acquire reference data for FFM, lean soft tissue (LST), and appendicular lean soft tissue (ALST). The validation of the newly developed predictive equations was conducted through regression analysis, Bland–Altman tests, and the area under the curves (AUC) of regression receiver operating characteristic (RROC) curves. Results Developed models were: FFM = − 7.729 + (body mass × 0.686) + (stature2/R × 0.227) + (Xc × 0.086) + (age × 0.058), R2 = 0.97, Standard error of estimation (SEE) = 1.0 kg; LST = − 8.929 + (body mass × 0.635) + (stature2/R × 0.244) + (Xc × 0.093) + (age × 0.048), R2 = 0.96, SEE = 0.9 kg; ALST = − 24.068 + (body mass × 0.347) + (stature2/R × 0.308) + (Xc × 0.152), R2 = 0.88, SEE = 1.4 kg. Train-test validation, performed on the validation group, revealed that generalized formulas for athletes underestimated all the predicted FFM components (p 0.05), with R2 values ranging from 0.83 to 0.91, and no trend (p > 0.05). The AUC scores of the RROC curves indicated an accuracy of 0.92, 0.92, and 0.74 for FFM, LST, and ALST, respectively. Conclusions The utilization of generalized predictive equations leads to an underestimation of FFM and ALST in elite soccer players. The newly developed soccer-specific formulas enable valid estimations of body composition while preserving the portability of a field-based method.
- Published
- 2023
- Full Text
- View/download PDF
3. Athletic bioimpedance-based equations underestimate fat free mass components in male elite soccer players: development and validation of new soccer-specific predictive models.
- Author
-
Campa, Francesco, Bongiovanni, Tindaro, Rossi, Alessio, Cerullo, Giuseppe, Casolo, Andrea, Martera, Giulia, Trecroci, Athos, Moro, Tatiana, and Paoli, Antonio
- Subjects
- *
LEAN body mass , *ELITE athletes , *SKINFOLD thickness , *MALE athletes , *PREDICTION models , *DUAL-energy X-ray absorptiometry , *BODY composition - Abstract
Background: Bioelectrical impedance analysis (BIA) is a rapid and user-friendly technique for assessing body composition in sports. Currently, no sport-specific predictive equations are available, and the utilization of generalized formulas can introduce systematic bias. The objectives of this study were as follows: (i) to develop and validate new predictive models for estimating fat-free mass (FFM) components in male elite soccer players; (ii) to evaluate the accuracy of existing predictive equations. Methods: A total of 102 male elite soccer players (mean age 24.7 ± 5.7 years), participating in the Italian first league, underwent assessments during the first half of the in-season period and were randomly divided into development and validation groups. Bioelectrical resistance (R) and reactance (Xc), representing the bioimpedance components, were measured using a foot-to-hand BIA device at a single frequency of 50 kHz. Dual-energy X-ray absorptiometry was employed to acquire reference data for FFM, lean soft tissue (LST), and appendicular lean soft tissue (ALST). The validation of the newly developed predictive equations was conducted through regression analysis, Bland–Altman tests, and the area under the curves (AUC) of regression receiver operating characteristic (RROC) curves. Results: Developed models were: FFM = − 7.729 + (body mass × 0.686) + (stature2/R × 0.227) + (Xc × 0.086) + (age × 0.058), R2 = 0.97, Standard error of estimation (SEE) = 1.0 kg; LST = − 8.929 + (body mass × 0.635) + (stature2/R × 0.244) + (Xc × 0.093) + (age × 0.048), R2 = 0.96, SEE = 0.9 kg; ALST = − 24.068 + (body mass × 0.347) + (stature2/R × 0.308) + (Xc × 0.152), R2 = 0.88, SEE = 1.4 kg. Train-test validation, performed on the validation group, revealed that generalized formulas for athletes underestimated all the predicted FFM components (p < 0.01), while the new predictive models showed no mean bias (p > 0.05), with R2 values ranging from 0.83 to 0.91, and no trend (p > 0.05). The AUC scores of the RROC curves indicated an accuracy of 0.92, 0.92, and 0.74 for FFM, LST, and ALST, respectively. Conclusions: The utilization of generalized predictive equations leads to an underestimation of FFM and ALST in elite soccer players. The newly developed soccer-specific formulas enable valid estimations of body composition while preserving the portability of a field-based method. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
4. New bioelectrical impedance vector references and phase angle centile curves in 4,367 adults: The need for an urgent update after 30 years.
- Author
-
Campa, Francesco, Coratella, Giuseppe, Cerullo, Giuseppe, Stagi, Silvia, Paoli, Samuele, Marini, Sofia, Grigoletto, Alessia, Moroni, Alessia, Petri, Cristian, Andreoli, Angela, Ceolin, Chiara, Degan, Raffaella, Izzicupo, Pascal, Sergi, Giuseppe, Mascherini, Gabriele, Micheletti Cremasco, Margherita, Marini, Elisabetta, Toselli, Stefania, Moro, Tatiana, and Paoli, Antonio
- Abstract
The bioelectrical impedance vector analysis (BIVA) represents a qualitative analysis of body composition. The vector, defined by resistance (R) and reactance (Xc) standardized by stature, can be evaluated compared to the 50%,75%, and 95% tolerance ellipses representative of the reference populations. The tolerance ellipses for healthy adults have been provided in 1995 and were developed by mixing underage, adult, and elderly subjects, possibly misrepresenting the actual adult population. The current multicentric, cross-sectional study aimed to provide new tolerance ellipses specific for the general adult population and as a secondary aim to present centile curves for the bioelectrical phase angle. R, Xc, and phase angle were measured in 2137 and 2230 males and females using phase-sensitive foot-to-hand analyzers at 50 kHz. A minimum of 35 subjects were included for each sex and age category from 18 to 65 years. The new mean vectors showed a leftward shift on the R–Xc graph with respect to the former reference values (males: F = 75.3; p < 0.001; females: F = 36.6, p < 0.001). The results provided new 3rd, 5th, 10th, 25th, 50th, 75th, 90th, 95th, and 97th percentile curves for phase angle, identifying time point phases of decrement (males: −0.03° per year at 33.0–51.0 years and −0.05° per year after 51 years; females: −0.03° per year from 37.2 to 57.9 years). Compared to the original references, the new data are characterized by a different distribution within the R-Xc graph with a higher phase angle. Thirty years after the BIVA invention, the current study presents new tolerance ellipses and phase angle reference values for the adult population. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
5. Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment.
- Author
-
Cancello, Raffaella, Brunani, Amelia, Brenna, Ettore, Soranna, Davide, Bertoli, Simona, Zambon, Antonella, Lukaski, Henry C., and Capodaglio, Paolo
- Abstract
Phase angle (PhA) is a recently proposed marker of nutritional status in many clinical conditions. Its use in patients with obesity presents different critical concerns due to the higher variability of the two measured parameters (resistance, R, and reactance, Xc) that contribute to the determination of PhA. Controversial is the relation between PhA and BMI that might vary with graded levels of obesity due to the variation in fat and free fat mass. Obesity is frequently associated with metabolic, hepatic, cardiovascular and kidney diseases that introduce variations in PhA values, in relation to multimorbidity and severity degree of these diseases. It is reported that the improvement of clinical condition is associated with a positive change in PhA. Also, the treatment of obesity with weight loss might confirm this effect, but with different responses in relation to the type and duration of the intervention applied. In fact, the effect appears not only related to the percentage of weight loss but also the possible loss of free fat mass and the nutritional, metabolic and structural modifications that might follow each therapeutic approach to decrease body weight. We can conclude that the PhA could be used as marker of health status in patients with obesity supporting an appropriate weight loss intervention to monitor efficacy and fat free mass preservation. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
6. Effect of resistance training on bioelectrical phase angle in older adults: a systematic review with Meta-analysis of randomized controlled trials.
- Author
-
Campa, Francesco, Colognesi, Lucas Antonio, Moro, Tatiana, Paoli, Antonio, Casolo, Andrea, Santos, Leandro, Correia, Rafael Ribeiro, Lemes, Ítalo Ribeiro, Milanez, Vinícius Flávio, Christofaro, Diego Destro, Cyrino, Edilson Serpeloni, and Gobbo, Luís Alberto
- Abstract
Resistance training has been proposed as a valid practice to counteract the aging effect on body mass and its components, which can be easily evaluated though the bioelectrical impedance analysis. This study aimed to achieve a systematic review with meta-analysis on the impact of resistance training on bioelectrical proprieties in older adults. A literature review was done in four electronic databases up to 1 January 2022. The inclusion criteria were: (i) participants aged ≥ 60 years; (ii) resistance training lasted ≥ 8 weeks; (iii) measurement of raw bioelectrical parameters in randomized controlled study designs. The outcomes of the trial had to be bioelectrical phase angle (PhA), resistance (R), and reactance (Xc). The methodological quality was assessed using the Rosendal scale. Overall, seven studies with a total of 344 participants were eligible for the analysis. The quality assessment yielded a score of 71.3%. Bioelectrical PhA (0.52 degree [95%CI 0.32, 0.71], p < 0.001) and Xc (3.58 ohms [95%CI 1.97, 5.19], p < 0.001) increased, whereas R decreased (-28.50 ohms [95%CI -41.39, -15.60], p < 0.001) after the resistance training programs. In this meta-analysis, resistance training promoted increases of PhA, which result from an increase in Xc concomitant with a reduction in R. According to the bioimpedance vector analysis, resistance-trained people experienced a beneficial leftward vector displacement, whilst inactivity induced a rightward vector displacement within the R-Xc graph. In future, more sophisticated and rigorous studies that address specific criteria, methods and targeted designs are required to identify which equipment and protocols allow for an optimization of the resistance training effects. Registration code in PROSPERO: CRD42020168057. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
7. Bioelectrical Impedance Vector Analysis Discriminates Aerobic Power in Futsal Players: The Role of Body Composition.
- Author
-
Matias, Catarina N., Campa, Francesco, Cerullo, Giuseppe, D'Antona, Giuseppe, Giro, Rita, Faleiro, João, Reis, Joana F., Monteiro, Cristina P., Valamatos, Maria J., and Teixeira, Filipe J.
- Subjects
- *
BODY composition , *BIOELECTRIC impedance , *AEROBIC capacity , *INDOOR soccer , *VECTOR analysis , *MUSCLE mass - Abstract
Simple Summary: Bioelectrical and body composition proprieties are linked to health status and physical performance. The bioelectrical impedance vector analysis (BIVA) is a valid approach for qualitatively and timely assessing body components in sports practice. However, it is still unclear, if bioimpedance vector patterns can provide relevant information regarding the aerobic power. For the first time, this study shows that BIVA is useful in discriminating professional futsal players according to their VO2max. In addition, fat mass and bioelectrical phase angle were identified as valid predictors for aerobic power. Aims: The present study aimed to assess the ability of bioelectrical impedance vector analysis (BIVA) in discriminating fitness levels in futsal players, exploring the association of body composition and bioelectrical parameters with aerobic power. Methods: Forty-eight professional futsal players (age 23.8 ± 5.3 years) were involved in a cross-sectional study during their pre-season phase. Fat mass (FM) and muscle mass were determined by dual-energy X-ray absorptiometry. VO2max was obtained by indirect calorimetry through a graded exercise test performed on a treadmill. Bioelectrical resistance (R), reactance (Xc), and phase angle (PhA) were directly measured using a foot-to-hand bioimpedance technology at a 50 kHz frequency. Bioelectric R and Xc were standardized for the participants' height and used to plot the bioimpedance vector in the R-Xc graph according to the BIVA approach. Results: The participants divided into groups of VO2max limited by tertiles showed significant differences in mean vector position in the R-Xc graph (p < 0.001), where a higher VO2max resulted in a longer vector and upper positioning. FM, muscle mass, and PhA differed (p < 0.01) among the athletes grouped by tertiles of VO2max, where athletes with a greater aerobic power showed a lower percentage of FM and a higher percentage of muscle mass and PhA. FM and PhA were associated with VO2max (FM: r = −0.658, p < 0.001; PhA: r = 0.493, p < 0.001). These relationships remained significant after adjusting for age and body mass (FM: ß = −0.335, p = 0.046; PhA: ß = 0.351, p = 0.003). Conclusions: Bioelectrical impedance vectors positioned on the lower pole of the R-Xc graph identified futsal players with a lower VO2max, while longer vectors corresponded to a greater aerobic power. Additionally, PhA, that describes the vector direction, was positively associated with VO2max, while a higher FM negatively affected VO2max in the futsal players. BIVA and PhA evaluation may represent a valid support for screening the aerobic fitness level in professional futsal players, when more sophisticated assessment methods are not available. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
8. Athlete or Non-athlete? This Is the Question in Body Composition.
- Author
-
Campa, Francesco and Coratella, Giuseppe
- Subjects
BODY composition ,ATHLETES ,SPORTS participation ,ADIPOSE tissues - Abstract
Despite their body composition features, some exercisers could not have the requisites to be defined as athletes, and consequently body composition might be estimated less accurately using equations developed for the general population. Similarly, a person who carries out manual works such as farmers, builders, or a gym attender that does not compete in organized events or is not affiliated with a sports team could nevertheless have similar body composition characteristics to those of an athlete. Consequently, practitioners simply use equations for athletes when specific so-defined athletes are tested or generalized equations when exercisers or different populations are involved. Exercisers and athletes with similar body composition could show a similar phase angle, we suggest setting specific thresholds to define when generalized or formula for athletes should be used. [Extracted from the article]
- Published
- 2021
- Full Text
- View/download PDF
9. Athlete or Non-athlete? This Is the Question in Body Composition
- Author
-
Francesco Campa and Giuseppe Coratella
- Subjects
BIA ,BIVA ,resistance training ,phase angle ,predictive equations ,Physiology ,QP1-981 - Published
- 2021
- Full Text
- View/download PDF
10. Bioelectrical Impedance Vector Analysis Discriminates Aerobic Power in Futsal Players: The Role of Body Composition
- Author
-
Catarina N. Matias, Francesco Campa, Giuseppe Cerullo, Giuseppe D’Antona, Rita Giro, João Faleiro, Joana F. Reis, Cristina P. Monteiro, Maria J. Valamatos, and Filipe J. Teixeira
- Subjects
athletes ,BIA ,BIVA ,fat mass ,phase angle ,performance ,Biology (General) ,QH301-705.5 - Abstract
Aims: The present study aimed to assess the ability of bioelectrical impedance vector analysis (BIVA) in discriminating fitness levels in futsal players, exploring the association of body composition and bioelectrical parameters with aerobic power. Methods: Forty-eight professional futsal players (age 23.8 ± 5.3 years) were involved in a cross-sectional study during their pre-season phase. Fat mass (FM) and muscle mass were determined by dual-energy X-ray absorptiometry. VO2max was obtained by indirect calorimetry through a graded exercise test performed on a treadmill. Bioelectrical resistance (R), reactance (Xc), and phase angle (PhA) were directly measured using a foot-to-hand bioimpedance technology at a 50 kHz frequency. Bioelectric R and Xc were standardized for the participants’ height and used to plot the bioimpedance vector in the R-Xc graph according to the BIVA approach. Results: The participants divided into groups of VO2max limited by tertiles showed significant differences in mean vector position in the R-Xc graph (p < 0.001), where a higher VO2max resulted in a longer vector and upper positioning. FM, muscle mass, and PhA differed (p < 0.01) among the athletes grouped by tertiles of VO2max, where athletes with a greater aerobic power showed a lower percentage of FM and a higher percentage of muscle mass and PhA. FM and PhA were associated with VO2max (FM: r = −0.658, p < 0.001; PhA: r = 0.493, p < 0.001). These relationships remained significant after adjusting for age and body mass (FM: ß = −0.335, p = 0.046; PhA: ß = 0.351, p = 0.003). Conclusions: Bioelectrical impedance vectors positioned on the lower pole of the R-Xc graph identified futsal players with a lower VO2max, while longer vectors corresponded to a greater aerobic power. Additionally, PhA, that describes the vector direction, was positively associated with VO2max, while a higher FM negatively affected VO2max in the futsal players. BIVA and PhA evaluation may represent a valid support for screening the aerobic fitness level in professional futsal players, when more sophisticated assessment methods are not available.
- Published
- 2022
- Full Text
- View/download PDF
11. Bioelectrical Impedance Vector and Creatine Phosphokinase Changes Induced by a High-Intensity Training Session in Rink Hockey Players
- Author
-
Álex Cebrián-Ponce, Manuel V. Garnacho-Castaño, Mercè Castellano-Fàbrega, Jorge Castizo-Olier, Marta Carrasco-Marginet, Noemí Serra-Paya, and Alfredo Irurtia
- Subjects
BIA ,BIVA ,creatine phosphokinase ,rectus femoris ,hydration status ,muscle damage ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
This study aimed to analyze anthropometric and whole-body/muscle-localized bioelectrical impedance vector analysis (BIVA) adaptations and their relation to creatine kinase (CK) as a biomarker of muscle damage in a group of seven male players in the maximum category of professional rink hockey. There were three checkpoint assessments in relation to a high-intensity training session: pre-session (PRE), post-session (POST), and 24 h-post-session (POST24H). The resistance, reactance, and impedance module were adjusted by height (R/h, Xc/h, and Z/h, respectively). The Wilcoxon signed-rank test was used to compare the data at baseline and follow-up, while Spearman correlation was used to explore the relationship between CK and the rest of the parameters. The results registered a decrease in body mass at POST (p = 0.03) and a reestablishment at POST24H (p = 0.02). Whole-body BIVA registered a significant increase in R/h between PRE–to–POST (p = 0.02) and returned to baseline values at POST24H (p = 0.02), which was expected since this parameter is related to hydration processes. Muscle-localized BIVA in the rectus femoris muscle showed an increase in both Xc/h and phase angle in POST (p = 0.04 and p = 0.03, respectively) and a decrease in Xc/h at POST24H (p = 0.02). CK correlated with R/h in the rectus femoris at all the checkpoints (PRE–to–POST: r = 0.75, p = 0.05; PRE–to–POST24H: r = 0.81, p = 0.03; POST–to–POST24H: r = 0.82, p = 0.02). Our results indicate that BIVA is a sensitive methodology to assess general and muscle-localized hydration induced by a high-intensity training session in rink hockey players. A correlation between BIVA and CK was also reported.
- Published
- 2022
- Full Text
- View/download PDF
12. Effects of the COVID-19 Lockdown on Body Composition and Bioelectrical Phase Angle in Serie A Soccer Players: A Comparison of Two Consecutive Seasons
- Author
-
Francesco Campa, Tindaro Bongiovanni, Athos Trecroci, Alessio Rossi, Gianpiero Greco, Giulio Pasta, and Giuseppe Coratella
- Subjects
BIA ,BIVA ,coronavirus disease ,detraining ,fat mass ,football ,Biology (General) ,QH301-705.5 - Abstract
The present study compared changes in body composition during the COVID-19-associated lockdown with the same period of the following season in elite soccer players. Fifteen elite male soccer players (30.5 ± 3.6 years.) underwent a bioelectrical impedance analysis (BIA) before (end of February) and after (end of May) the lockdown, which occurred during the 2019/2020 season, and at the same period during the following competitive season in 2020/2021, when restrictions were lifted. Fat and muscle mass were estimated using predictive equations, while phase angle (PhA) and bioelectrical impedance vector analysis (BIVA) patterns were directly measured. After lockdown, fat mass remained unchanged (p > 0.05), while muscle mass (95%CI = −1.12/−0.64; ES = −2.04) and PhA (95%CI = 0.51/−0.24, ES = −1.56) decreased. A rightward displacement of the BIVA vector was also found (p < 0.001, ES = 1.50). After the same period during the regular season, FM% and muscle mass did not change (p > 0.05), while the PhA increased (95%CI = 0.01/0.22; ES = 0.63). A leftward vector displacement (p < 0.001, ES = 1.05) was also observed. The changes in muscle mass correlated with changes in PhA (“lockdown” season 2019/2020: ß = −1.128, p = 0.011; “regular” season 2020/21: ß = 1.963, p = 0.011). In conclusion, coaches and strength conditioners should monitor muscle mass in soccer players during detraining periods as this parameter appears to be mainly affected by changes in training plans.
- Published
- 2021
- Full Text
- View/download PDF
13. Prevalence of obesity and obesity-associated muscle wasting in patients on peritoneal dialysis.
- Author
-
Guida, Bruna, Trio, Rossella, Di Maro, Martina, Memoli, Andrea, Di Lauro, Teresa, Belfiore, Annamaria, Santillo, Mariarosaria, and Cataldi, Mauro
- Abstract
Background and Aims: A progressive decrease in muscle mass until full-blown sarcopenia may occur in patients on peritoneal dialysis (PD) and worsen their life quality and expectancy. Here we investigate the prevalence of obesity and obesity-associated muscle wasting in PD patients.Patients and Methods: The study design was observational, cross sectional. Body composition was assessed with BIA and BIVA in 88 PD patients (53.4 ± 13.1 years; 67% male). Patients with obesity and/or with reduced muscle mass were identified using FMI and SM/BW cutoff values, respectively. Inflammatory status was assessed by measuring CRP and fibrinogen blood levels.Results: A total of 44.3% of the patients showed a reduced muscle mass (37.5% moderate and 6.8% severe). The prevalence of obesity was 6.1%, 81.8%, and 100% in patients with normal, moderately, and severely reduced muscle mass, respectively (p < 0.05). Of the total, 15.2% of the patients with normal muscle mass, 18.4% of those with moderately reduced muscle mass, and 66.7% of those with severely reduced muscle mass had diabetes. The prevalence of severe muscle mass loss was higher in those with diabetes than in those without diabetes (22.2% vs. 2.8%, p < 0.05). Patients with obesity-associated muscle wasting showed higher fibrinogen (613.9 ± 155.1 vs. 512.9 ± 159.5 mg/dL, p < 0.05) and CPR (1.4 ± 1.3 vs. 0.6 ± 0.8 mg/dL, p < 0.05) blood concentrations than those with normal body composition.Conclusion: Obesity and diabetes were strongly associated with muscle mass loss in our PD patients. It remains to be established whether prevention of obesity with nutritional interventions can halt the occurrence of muscle mass loss in patients on PD. [ABSTRACT FROM AUTHOR]- Published
- 2019
- Full Text
- View/download PDF
14. Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment
- Author
-
Raffaella Cancello, Amelia Brunani, Ettore Brenna, Davide Soranna, Simona Bertoli, Antonella Zambon, Henry C. Lukaski, Paolo Capodaglio, Cancello, R, Brunani, A, Brenna, E, Soranna, D, Bertoli, S, Zambon, A, Lukaski, H, and Capodaglio, P
- Subjects
Phase angle ,Endocrinology ,BIA ,Endocrinology, Diabetes and Metabolism ,Bioelectrical impedance analysi ,BIVA ,Obesity ,Weight lo - Abstract
Phase angle (PhA) is a recently proposed marker of nutritional status in many clinical conditions. Its use in patients with obesity presents different critical concerns due to the higher variability of the two measured parameters (resistance, R, and reactance, Xc) that contribute to the determination of PhA. Controversial is the relation between PhA and BMI that might vary with graded levels of obesity due to the variation in fat and free fat mass. Obesity is frequently associated with metabolic, hepatic, cardiovascular and kidney diseases that introduce variations in PhA values, in relation to multimorbidity and severity degree of these diseases. It is reported that the improvement of clinical condition is associated with a positive change in PhA. Also, the treatment of obesity with weight loss might confirm this effect, but with different responses in relation to the type and duration of the intervention applied. In fact, the effect appears not only related to the percentage of weight loss but also the possible loss of free fat mass and the nutritional, metabolic and structural modifications that might follow each therapeutic approach to decrease body weight. We can conclude that the PhA could be used as marker of health status in patients with obesity supporting an appropriate weight loss intervention to monitor efficacy and fat free mass preservation.
- Published
- 2022
15. Biological Mechanisms Underlying Physical Fitness and Sports Performance.
- Author
-
Georgian, Badicu, Clemente, Filipe Manuel, Georgian, Badicu, and Murawska-Ciałowicz, Eugenia
- Subjects
Biology, life sciences ,Research & information: general ,25(OH)D ,BIA ,BIVA ,FTP ,HRQoL ,IgA ,Paralympic Powerlifting ,Tabata training ,acid-base balance ,acute exercise ,adolescent ,aerobic capacity ,aerobic training ,age ,antioxidant ,aquatic training ,athletic performance ,back squat ,biological mechanisms ,blood pressure ,body composition ,body fat ,cancer survivorship ,cardiac autonomic modulation ,cardiorespiratory fitness ,cardiovascular fitness ,chronic low back pain ,cognitive performance ,combined training ,core endurance test ,coronavirus disease ,cycling ,depression ,detraining ,dry land training ,electromyography ,endurance ,ergogenic aids ,erythroferrone ,erythropoietin ,executive functions ,exercise ,fat mass ,flanker ,football ,glucagon-like peptide-1 ,glucose-dependent insulinotropic polypeptide ,health ,heart rate ,heart rate recovery ,heart rate variability ,high-intensity ,high-intensity exercise ,high-intensity interval training ,high-speed running ,hormonal response ,hormones ,hypoxic dose ,ibuprofen ,immunomodulation ,inflammation ,kickboxing ,kinanthropometry ,knowledge ,lean body mass ,load ,log-linear analysis ,mathematical model ,mental health ,metabolic acidosis ,monotony ,multivariate correspondence analysis ,muscle damage ,muscle fatigue ,muscle mass ,muscle regeneration ,muscle soreness ,muscle strength ,muscular activity ,muscular endurance ,muscular performance ,myogenic regulatory factors ,n/a ,non-planned agility ,nutritional supplement ,obesity ,one repetition maximum ,oxidative stress ,oxygen uptake ,performance ,physical activity ,physical education ,physical education lessons ,physical exercise ,physical health ,physiology of performances ,power ,pre-planned agility ,psychophysiological responses ,puberty ,recovery ,recovery of function ,resistance training ,rheumatic diseases ,rowing ,saliva ,satellite cells ,sex difference ,skin surface temperature ,sleep ,small-sided games ,soccer ,spinal cord injury ,sport ,sports ,sports and exercise physiology ,sprint ,strain ,strength ,strength training ,stress ,surface electromyography ,swimming performance ,team sports ,thermal imaging ,threshold ,triathlon ,tumour ,type 2 diabetes ,vibrating exercise equipment ,water parachute ,weight loss ,women ,young athlete ,youth - Abstract
Summary: The concept of mechanism in biology has three distinct meanings. It may refer to a philosophical thesis about the nature of life and biology, to the internal workings of a machine-like structure, or to the causal explanation of a particular phenomenon. In this Special Issue, we try to discuss these possible biological mechanisms that underlie the beneficial effects of physical fitness and sports performance, as well their importance and role/influences on physical health.Despite the significant body of knowledge regarding the physiological and physical effects of different training methods (based on dimensions of load), some of the biological causes for those changes are still unknown. Additionally, few studies have focused on the natural biological variability in humans and how specific properties of humans may justify different effects for the same training intervention. Thus, more original research is needed to provide plausible biological mechanisms that may explain the physiological and physical effects of exercise and training in humans.In this Special Issue, we gather the contributions that describe and list the links between physical fitness, sports performance, and human biology.
16. Comparison of generalized and athletic bioimpedance-based predictive equations for estimating fat-free mass in resistance-trained exercisers
- Author
-
Francesco Campa, Catarina N. Matias, Filipe J. Teixeira, Joana F. Reis, Maria J. Valamatos, Giuseppe Coratella, and Cristina P. Monteiro
- Subjects
Adult ,Male ,Nutrition and Dietetics ,Endocrinology, Diabetes and Metabolism ,Reproducibility of Results ,BIVA ,predictive equations ,Body Mass Index ,fat-free mass ,Young Adult ,Absorptiometry, Photon ,BIA ,Body Composition ,Electric Impedance ,Humans ,Sports - Abstract
This study aimed to test whether athlete-specific, bioelectrical, impedance-based equations to estimate fat-free mass (FFM) could be more accurate than generalized equations when testing resistance-trained exercisers.A total of 50 resistance-trained men (age 30.9 ± 7.4 y; body mass index: 25.3 ± 2.2 kg/mCompared with DXA, when assessing the resistance-trained participants, the athletic-specific equation had neither mean (-0.89 kg; P = 0.789) or proportional bias (r = -0.104; P = 0.474) with a coefficient of determination equal to RWhen assessing body composition in resistance-trained exercisers, specific equations for athletes should be preferred to generalized ones to avoid an overestimation in FFM. Furthermore, athlete-specific and generalized formulas cannot be used interchangeably, even when assessing body composition in the general population.
- Published
- 2022
17. Effect of resistance training on bioelectrical phase angle in older adults: a systematic review with Meta-analysis of randomized controlled trials
- Author
-
Francesco Campa, Lucas Antonio Colognesi, Tatiana Moro, Antonio Paoli, Andrea Casolo, Leandro Santos, Rafael Ribeiro Correia, Ítalo Ribeiro Lemes, Vinícius Flávio Milanez, Diego Destro Christofaro, Edilson Serpeloni Cyrino, and Luís Alberto Gobbo
- Subjects
Aging ,Phase angle ,Endocrinology ,BIA ,BIVA ,Body composition ,Strength ,Endocrinology, Diabetes and Metabolism - Abstract
Resistance training has been proposed as a valid practice to counteract the aging effect on body mass and its components, which can be easily evaluated though the bioelectrical impedance analysis. This study aimed to achieve a systematic review with meta-analysis on the impact of resistance training on bioelectrical proprieties in older adults.A literature review was done in four electronic databases up to 1 January 2022. The inclusion criteria were: (i) participants aged ≥ 60 years; (ii) resistance training lasted ≥ 8 weeks; (iii) measurement of raw bioelectrical parameters in randomized controlled study designs.The outcomes of the trial had to be bioelectrical phase angle (PhA), resistance (R), and reactance (Xc). The methodological quality was assessed using the Rosendal scale.Overall, seven studies with a total of 344 participants were eligible for the analysis. The quality assessment yielded a score of 71.3%. Bioelectrical PhA (0.52 degree [95%CI 0.32, 0.71], p In this meta-analysis, resistance training promoted increases of PhA, which result from an increase in Xc concomitant with a reduction in R. According to the bioimpedance vector analysis, resistance-trained people experienced a beneficial leftward vector displacement, whilst inactivity induced a rightward vector displacement within the R-Xc graph. In future, more sophisticated and rigorous studies that address specific criteria, methods and targeted designs are required to identify which equipment and protocols allow for an optimization of the resistance training effects.Registration code in PROSPERO: CRD42020168057.
- Published
- 2022
18. Evaluation of body composition with bioimpedence. A comparison between athletic and non-athletic children.
- Author
-
Meleleo, Domenico, Bartolomeo, Nicola, Cassano, Liliana, Nitti, Alessandro, Susca, Giovanna, Mastrototaro, Giuseppina, Armenise, Umberto, Zito, Annapaola, Devito, Fiorella, Scicchitano, Pietro, and Ciccone, Marco Matteo
- Subjects
- *
BODY composition , *ADIPOSE tissues , *ANTHROPOMETRY , *COMPARATIVE studies , *BIOELECTRIC impedance , *LONGITUDINAL method , *PROBABILITY theory , *WATER in the body , *WATER-electrolyte balance (Physiology) , *SPORTS participation , *LEAN body mass , *DESCRIPTIVE statistics , *CHILDREN - Abstract
Purpose:Conventional Bioelectrical Impedance Analysis (BIA) or Bioelectrical Impedance Vector Analysis (BIVA) can provide direct evaluations of body composition. The purpose of this study was to evaluate lean and fat mass (FM), and hydration of children involved in daily competitive sports.Methods:190 non-athletic [8.2–10.5 years] and 29 competitive children [8.0–10.5 years] were enrolled. They were evaluated: at baseline (t0), 6 months (t1) and one year (t2). Anthropometric, BIA and BIVA, lean and FM, and hydration evaluations were performed.Results:Resistance (R/h) and reactance (Xc/h) were lower att0 in competitive individuals when compared to controls. Xc/h (+3.28) significantly increases in competitive when compared to non-competitive individuals (+0.66,pfor difference: 0.011), while phase angle (PA) was lower att0 (5.72 vs. 6.17,p < .001) and after 6 months (p = .001). Total body water adjusted for height (TBW/h) significantly increased only in non-athletes (+0.50 ± 0.13,p < .001) betweent0andt1. Att1, extracellular water (ECW) significantly decreased (p = .026) in the two groups: −0.45 ± 0.19% in non-competitive, −1.63 ± 0.49% in competitive subjects, while intracellular water (ICW) increased. At one-year follow-up (t2), there were no statistically significant differences in R/h, Xc/h and PA in competitive individuals when compared to baseline andt1. Furthermore, we observed att2that hours/week of training, age, male gender and body mass index can influence FFM/h and FM/h in both competitive and non-competitive subjects. In particular, a direct correlation was for hours/week and FFM/h, inverse for hours/week and FM/h.Conclusions:Body mass index does not allow evaluating differences in lean body mass and FM between athletes and non-athletes. BIA and BIVA can give more reliable details about body composition differences in competitive adolescents and non-competitive, outlining a progressive decline in ECW and increase in ICW without affecting TBW composition of athletes. [ABSTRACT FROM PUBLISHER]
- Published
- 2017
- Full Text
- View/download PDF
19. Effects of the COVID-19 Lockdown on Body Composition and Bioelectrical Phase Angle in Serie A Soccer Players: A Comparison of Two Consecutive Seasons
- Author
-
Giulio Pasta, Athos Trecroci, Alessio Rossi, Gianpiero Greco, Giuseppe Coratella, Tindaro Bongiovanni, and Francesco Campa
- Subjects
football ,BIA ,BIVA ,coronavirus disease ,detraining ,fat mass ,muscle mass ,team sports ,General Immunology and Microbiology ,Coronavirus disease 2019 (COVID-19) ,QH301-705.5 ,Phase angle ,Biology ,Muscle mass ,Article ,General Biochemistry, Genetics and Molecular Biology ,Fat mass ,Animal science ,Biology (General) ,General Agricultural and Biological Sciences ,Bioelectrical impedance analysis ,human activities - Abstract
The present study compared changes in body composition during the COVID-19-associated lockdown with the same period of the following season in elite soccer players. Fifteen elite male soccer players (30.5 ± 3.6 years.) underwent a bioelectrical impedance analysis (BIA) before (end of February) and after (end of May) the lockdown, which occurred during the 2019/2020 season, and at the same period during the following competitive season in 2020/2021, when restrictions were lifted. Fat and muscle mass were estimated using predictive equations, while phase angle (PhA) and bioelectrical impedance vector analysis (BIVA) patterns were directly measured. After lockdown, fat mass remained unchanged (p >, 0.05), while muscle mass (95%CI = −1.12/−0.64, ES = −2.04) and PhA (95%CI = 0.51/−0.24, ES = −1.56) decreased. A rightward displacement of the BIVA vector was also found (p <, 0.001, ES = 1.50). After the same period during the regular season, FM% and muscle mass did not change (p >, 0.05), while the PhA increased (95%CI = 0.01/0.22, ES = 0.63). A leftward vector displacement (p <, 0.001, ES = 1.05) was also observed. The changes in muscle mass correlated with changes in PhA (“lockdown” season 2019/2020: ß = −1.128, p = 0.011, “regular” season 2020/21: ß = 1.963, p = 0.011). In conclusion, coaches and strength conditioners should monitor muscle mass in soccer players during detraining periods as this parameter appears to be mainly affected by changes in training plans.
- Published
- 2021
- Full Text
- View/download PDF
20. Effects of the COVID-19 Lockdown on Body Composition and Bioelectrical Phase Angle in Serie A Soccer Players: A Comparison of Two Consecutive Seasons.
- Author
-
Campa, Francesco, Bongiovanni, Tindaro, Trecroci, Athos, Rossi, Alessio, Greco, Gianpiero, Pasta, Giulio, and Coratella, Giuseppe
- Subjects
- *
MUSCLE mass , *BODY composition , *COVID-19 pandemic , *COVID-19 , *SOCCER players , *ADIPOSE tissues - Abstract
Simple Summary: In 2020, the first Italian soccer league (Serie A) was canceled due to the COVID-19 pandemic. Consequently, a detraining process was triggered in soccer players, leading coaches and sports scientists to implement alternative training strategies to prevent a remodeling in body composition. This study tested the hypothesis that male elite soccer players, when confined to their home during the coronavirus disease 2019 pandemic, will display unfavorable trends in bioelectrical and body composition parameters. The results of the present study showed that reduction in phase angle and muscle mass occurred in soccer players during the coronavirus disease 2019 pandemic lockdown. Recognizing these adverse effects of a detraining period is critical in avoiding adverse effects on body composition in soccer players. In addition, the bioelectrical phase angle has been identified as a valid predictor of muscle mass changes during the competitive soccer season. Considerably, the phase angle represents a parameter that can be measured directly through bioelectrical impedance analysis, and it is independent of predictive equations such as those that quantify muscle mass. The present study compared changes in body composition during the COVID-19-associated lockdown with the same period of the following season in elite soccer players. Fifteen elite male soccer players (30.5 ± 3.6 years.) underwent a bioelectrical impedance analysis (BIA) before (end of February) and after (end of May) the lockdown, which occurred during the 2019/2020 season, and at the same period during the following competitive season in 2020/2021, when restrictions were lifted. Fat and muscle mass were estimated using predictive equations, while phase angle (PhA) and bioelectrical impedance vector analysis (BIVA) patterns were directly measured. After lockdown, fat mass remained unchanged (p > 0.05), while muscle mass (95%CI = −1.12/−0.64; ES = −2.04) and PhA (95%CI = 0.51/−0.24, ES = −1.56) decreased. A rightward displacement of the BIVA vector was also found (p < 0.001, ES = 1.50). After the same period during the regular season, FM% and muscle mass did not change (p > 0.05), while the PhA increased (95%CI = 0.01/0.22; ES = 0.63). A leftward vector displacement (p < 0.001, ES = 1.05) was also observed. The changes in muscle mass correlated with changes in PhA ("lockdown" season 2019/2020: ß = −1.128, p = 0.011; "regular" season 2020/21: ß = 1.963, p = 0.011). In conclusion, coaches and strength conditioners should monitor muscle mass in soccer players during detraining periods as this parameter appears to be mainly affected by changes in training plans. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
21. Prevalence of obesity and obesity-associated muscle wasting in patients on peritoneal dialysis
- Author
-
Rossella Trio, Mauro Cataldi, Mariarosaria Santillo, A. Belfiore, Martina Di Maro, Teresa Di Lauro, Bruna Guida, Andrea Memoli, Guida, B., Trio, R., Di Maro, M., Memoli, A., Di Lauro, T., Belfiore, A., Santillo, M., and Cataldi, M.
- Subjects
Male ,Sarcopenia ,Endocrinology, Diabetes and Metabolism ,medicine.medical_treatment ,Medicine (miscellaneous) ,BIVA ,030204 cardiovascular system & hematology ,Gastroenterology ,Muscle wasting ,0302 clinical medicine ,Risk Factors ,Prevalence ,Wasting ,Inflammation Mediator ,Nutrition and Dietetics ,Diabetes Mellitu ,Middle Aged ,medicine.anatomical_structure ,C-Reactive Protein ,Italy ,Body Composition ,Female ,medicine.symptom ,Inflammation Mediators ,Cardiology and Cardiovascular Medicine ,Peritoneal Dialysis ,Human ,Adult ,medicine.medical_specialty ,030209 endocrinology & metabolism ,Risk Assessment ,Peritoneal dialysis ,Peritoneal Dialysi ,03 medical and health sciences ,Diabetes mellitus ,Internal medicine ,BIA ,medicine ,Diabetes Mellitus ,Humans ,Obesity ,Dialysis ,Aged ,Cross-Sectional Studie ,business.industry ,Risk Factor ,Skeletal muscle ,Fibrinogen ,Biomarker ,medicine.disease ,Cross-Sectional Studies ,Blood chemistry ,Kidney Failure, Chronic ,business ,Biomarkers - Abstract
Background and aims: A progressive decrease in muscle mass until full-blown sarcopenia may occur in patients on peritoneal dialysis (PD) and worsen their life quality and expectancy. Here we investigate the prevalence of obesity and obesity-associated muscle wasting in PD patients. Patients and methods: The study design was observational, cross sectional. Body composition was assessed with BIA and BIVA in 88 PD patients (53.4 ± 13.1 years; 67% male). Patients with obesity and/or with reduced muscle mass were identified using FMI and SM/BW cutoff values, respectively. Inflammatory status was assessed by measuring CRP and fibrinogen blood levels. Results: A total of 44.3% of the patients showed a reduced muscle mass (37.5% moderate and 6.8% severe). The prevalence of obesity was 6.1%, 81.8%, and 100% in patients with normal, moderately, and severely reduced muscle mass, respectively (p < 0.05). Of the total, 15.2% of the patients with normal muscle mass, 18.4% of those with moderately reduced muscle mass, and 66.7% of those with severely reduced muscle mass had diabetes. The prevalence of severe muscle mass loss was higher in those with diabetes than in those without diabetes (22.2% vs. 2.8%, p < 0.05). Patients with obesity-associated muscle wasting showed higher fibrinogen (613.9 ± 155.1 vs. 512.9 ± 159.5 mg/dL, p < 0.05) and CPR (1.4 ± 1.3 vs. 0.6 ± 0.8 mg/dL, p < 0.05) blood concentrations than those with normal body composition. Conclusion: Obesity and diabetes were strongly associated with muscle mass loss in our PD patients. It remains to be established whether prevention of obesity with nutritional interventions can halt the occurrence of muscle mass loss in patients on PD.
- Published
- 2019
22. The impact of 2 weeks of detraining on phase angle, BIVA patterns, and muscle strength in trained older adults.
- Author
-
Freitas, Sofia P., Júdice, Pedro B., Hetherington-Rauth, Megan, Magalhães, João P., Correia, Inês R., Lopes, Júlia M., Strong, Christopher, Matos, Daniel, and Sardinha, Luís B.
- Subjects
- *
OLDER people , *MUSCLE strength , *IMMUNOGLOBULINS , *MUSCLE histology , *HISTOLOGY - Abstract
An intermission in the training routine, in which older adults refrain from regular structured exercise, may have deleterious effects on muscle performance and bioelectric phase angle (PhA), which is a predictive marker for cellular integrity. To determine the effects of a 2-week detraining period on PhA and muscular strength (MS) in trained older adults. A total of 14 trained older adults (6 females) aged ≥65 years (77.2 ± 6.6) were assessed at baseline (i.e. trained condition) and after 2 weeks of detraining, where they refrained from their usual participation in structured exercise sessions. Whole-body resistance (R), reactance (Xc), and PhA were assessed using bioelectrical impedance analysis (BIA, single frequency, 50 kHz ± 1%, NutriLab, Akern). MS was assessed on both lower and upper limbs under isometric conditions. Differences between moments were examined using ANOVA for repeated measures, while adjusting for sex. Bioimpedance vector analysis (BIVA) was performed to evaluate changes in cellular function and body fluid content. Detraining resulted in declines in PhA (−4.34%) (p = 0.017). There was a significant difference in the mean impedance vectors from baseline to post-detraining (p < 0.05), which were driven by decreases in reactance (Xc) relative to height (Xc/H) with little change in resistance (R) relative to height (R/H) for both males and females. No differences were found in MS for both the leg press (p = 0.992) and bench press (p = 0.166) tests. A detraining period as short as 2-weeks is enough to cause alterations in the bodies bioelectrical properties, resulting in detrimental changes in PhA, due to alterations in cellular integrity, but not in MS. These results highlight the importance of maintaining structured exercise sessions in older adults, and reinforce the potential role of PhA as a sensitive predictor to detect acute changes in muscle cell integrity following alterations in exercise training. • A detraining period as short as 2-weeks is enough to cause detrimental changes in PhA • PhA may be a sensitive marker to detect acute changes in muscle cell integrity following a period of detraining • Older adults should maintain a frequent practice of structured exercise activities in order to prevent adverse health changes [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
23. Der Einfluss kritischer Erkrankung und inflammationsbedingter Organdysfunktion unterschiedlicher Ausprägung auf die Ganzkörperimpedanz
- Author
-
Steinhilp, Lina-Sophie
- Subjects
critical care ,systemic inflammation ,nutrition ,BIA ,ICU ,BIVA ,600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit ,body impedance - Abstract
Eine Möglichkeit den Ernährungsstatus eines Menschen zu bestimmen ist die Bioimpedanzananlyse (BIA). Mittels BIA werden die Wechselstromwiderstände Resistanz (R) und Reaktanz (Xc) gemessen. R korreliert negativ mit dem Gesamtkörperwasser, Xc korreliert positiv mit der Körperzellmasse. Erkrankungen verschiedener Genese beeinflussen die Ganzkörperimpedanz. Ziel unserer Studie ist herauszufinden in welchem Maße systemische Inflammation und assoziierte Organdysfunktionen einen Einfluss auf die Ganzkörperimpedanz haben. Hierfür wurde ein Vergleich der Impedanzwerte von Gesunden, leichter kritisch Kranken und schwerer kritisch Kranken definiert durch das Systemische Inflammatiorische Response-Syndrom (SIRS) und den Sequential Organ Failure Assessment Score (SOFA) angestellt. Der Unterschied zwischen diesen Gruppen zum ersten Messzeitpunkt stellt den primären Endpunkt dieser Studie dar. Sekundäre Endpunkte sind der Gruppenunterschied an den darauf folgenden Messzeitpunkten, die Veränderung der Impedanz über die Zeit, der Einfluss von Bilanz, Serumnatriumwert, Ödemen, Kategorie der Grunderkrankung und Körpertemperatur auf die Gruppenunterschiede zu den verschiedenen Messzeitpunkten. Es wurden 70 intensivmedizinische Patienten und 70 gematchte, gesunde Probanden eingeschlossen. Als die Gruppenaufteilung der Intensivpatienten bestimmendes Kriterium wurde mittels Regressionsanalyse ein SOFA-Score ≥ 8 Punkten an mindestens 2 Tagen innerhalb der ersten 4 Tage bei gleichzeitigem Vorliegen der SIRS-Kriterien festgelegt. 39 der Patienten erfüllten das Kriterium der Gruppenaufteilung nicht und fielen in Gruppe 1. 31 der Patienten mit einer stärkeren Ausprägung von Inflammation und inflammationsbedingtem Organversagen erfüllten das Kriterium und gehörten der Gruppe 2 an. Die Impedanzparameter der Gruppe 1, der Gruppe 2 und der Normalpopulation unterschieden sich zu M1 signifikant. Mit einer stärkeren Ausprägung von Inflammation und inflammationsassoziierter Organdysfunktion waren deutlich pathologischere, von der Normalpopulation stärker abweichende Impedanzparameter nachzuweisen. Die Plasmanatriumkonzentration und das Vorliegen von Ödemen waren signifikante Einflussfaktoren, die Kategorie der Grunderkrankung einen marginalen Einflussfaktor auf die Impedanzparameter zu M1. Auch zu den Messzeitpunkten M2 und M3 konnten ähnlicher Ergebnisse dargestellt werden. Hingegen wurde zu den Messzeitpunkten M4 und M5 zwar weiterhin ein deutlich signifikanter Gruppenunterschied mit pathologischeren Impedanzparametern in der Gruppe 2 errechnet, dieser war aber stärker durch die Kovariaten Serumnatriumkonzentration, dem Vorliegen von Ödemen und der Kategorie der Grunderkrankung verursacht, als von der Gruppenaufteilung an sich. Eine signifikante Veränderung der Impedanz über die Zeit wurde im Patientenkollektiv nicht nachgewiesen. Die Darstellung der Impedanzwerte eines Intensivpatientenkollektivs mittels nach Alter, BMI und Geschlecht genormten Z-Werten sowie die Untersuchung des Zusammenhangs zwischen Schwere der kritischen Erkrankung gemessen in SOFA und SIRS mit der Ganzkörperimpedanz sind die wissenschaftlichen Erkenntnisse dieser Arbeit. Limitiert ist die BIA durch Faktoren, welche in die Berechnungen der Studie zum Teil als Kovariaten einflossen., The metabolic status of human beings can be monitored through the analysis of bioelectrical impedance (BIA). BIA measures the impedance values resistance (R) and reactance (Xc). While R is negatively correlated with total body water, Xc is positively correlated with body cell mass. Illnesses of various genesis influence whole body impedance. Our study aimed to identify to which degree systemic inflammation and associated organ dysfunction influence whole body impedance. We compared the impedance values of healthy subjects, less severely critically ill patients and more severely critically ill patients. These were defined through criteria of Systemic Inflammation Response Syndrome (SIRS) and Sequential Organ Failure Assessment Score (SOFA). Primary endpoint of the study was the difference between these groups at the first measuring (M1). Secondary endpoints were group differences at following measuring (M2-M6), the change of impedance over time and the influence of fluid balance, plasma sodium concentration, oedema, category of primary illness and body temperature on differences within the groups at different measuring. 70 patients and 70 matched healthy subjects were included. A SOFA-Score ≥ 8 in at least 2 days within the first 4 days combined with positive SIRS criteria determined the dividing of intensive care patients using regression analysis. 39 patients who did not meet the criteria were assigned to group 1. 31 patients met the defining criteria and were assigned to group 2. Impedance values of group 1, group 2 and the healthy subjects differed significantly at M1. The higher the degree of inflammation and associated organ dysfunction, the more pathologic was the impedance measured, differing more strongly to healthy population. Plasma sodium concentration and oedema were significant factors of influence, the category of primary illness was a marginal factor of influence at M1, M2 and M3. In contrast, at M4 and M5 the highly significant group difference was caused more through the covariates plasma sodium concentration, existence of oedema and category of primary illness than through group division. No significant change of impedance in patients was detected over time. The scientific findings of this study are the description of impedance values in an intensive care patient collective using Z-values standardised by age, BMI and sex, as well as the investigation of the relation between severity of critical illness measured by SOFA and SIRS and whole body impedance. BIA is limited by factors which were in parts included in the calculation as covariates.
- Published
- 2015
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.