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7 results on '"Anke Sönmez"'

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1. The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512

2. Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes

3. PTBP1 is required for glucose-stimulated cap-independent translation of insulin granule proteins and Coxsackieviruses in beta cells

4. Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies

5. Stability of proICA512/IA-2 and its targeting to insulin secretory granules require β4-sheet-mediated dimerization of its ectodomain in the endoplasmic reticulum

7. Ectodomain dimerization of proICA512/IA-2 in the endoplasmic reticulum coordinates the conversion of the mature insulin secretory granule form

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