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Your search keyword '"Zhukova Os"' showing total 3 results
Start Over Author "Zhukova Os" Topic burkitt lymphoma
3 results on '"Zhukova Os"'

1. [Effect of L-lysine-alpha-oxidase on the cell cycle kinetics of cultured Burkitt's lymphoma cells].

Author

Zhukova OS, Khaduev SKh, Dobrynin IaV, Smirnova MP, and Lukasheva EV

Subjects
Burkitt Lymphoma metabolism, Cell Cycle drug effects, Cells, Cultured, DNA, Neoplasm biosynthesis, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Humans, Neoplasm Proteins biosynthesis, RNA, Neoplasm biosynthesis, Time Factors, Trichoderma enzymology, Amino Acid Oxidoreductases toxicity, Burkitt Lymphoma pathology
Abstract

L-lysine-alpha-oxidase from Trichoderma sp. fungi inhibits the synthesis of DNA, RNA and protein in cultivated cells of the Burkitt lymphoma (strain P3HRj) in vitro, which results in the blocking of the cells' transfer from phase S to phase G2/M of the mitotic cycle.

Published
1985

2. [Effect of gangliosides Gm1 and Gm3 on the binding, internalization and cytotoxic activity of ricin].

Author

Tonevitskiĭ AG, Zhukova OS, Timofeeva NV, and Bergel'son LD

Subjects
Burkitt Lymphoma immunology, G(M1) Ganglioside pharmacology, G(M3) Ganglioside pharmacology, Humans, Ricin immunology, Tumor Cells, Cultured immunology, Burkitt Lymphoma metabolism, Cytotoxicity, Immunologic, G(M1) Ganglioside metabolism, G(M3) Ganglioside metabolism, Gangliosides metabolism, Ricin metabolism, Tumor Cells, Cultured metabolism
Published
1987

3. A new approach to studies of cell-antibody interactions using fluorescent lipid probes

Author

Alexander G. Tonevitsky, Lev D. Bergelson, E. L. Arsen'eva, Zhukova Os, Manevich Em, and G. T. Bogacheva

Subjects
medicine.drug_class, (Burkitt lymphoma cell), Cell, Biophysics, Receptors, Antigen, B-Cell, Fluorescence Polarization, Monoclonal antibody, Biochemistry, Lipid fluorescence, Antigen-Antibody Reactions, Membrane Lipids, Fluorescent probe, Antigen, Structural Biology, Genetics, medicine, Tumor Cells, Cultured, Humans, Molecular Biology, Fluorescent Dyes, Liposome, biology, Chemistry, Cell Membrane, Cell Biology, Fluorescence, Burkitt Lymphoma, Antibodies, Anti-Idiotypic, Sphingomyelins, medicine.anatomical_structure, Immunoglobulin receptor, biology.protein, Immunoglobulin Light Chains, Antibody, Sphingomyelin, Fluorescence anisotropy
Abstract

The interaction of poly- and monoclonal antibodies against the L-chain of human Ig with Burkitt lymphoma EB-3 cells was studied using a fluorescent lipid probe, anthrylvinyl-labelled sphingomyelin, incorporated into the cell plasma membrane. Binding of the antibodies to Ig receptors on the surface was shown to induce changes in the fluorescence polarization of the probe. The high sensitivity of the method allows one to detect less than 100 antibody molecules per cell. The possibility of using cells or liposomes carrying antigens and fluorescent lipids for the determination of antibodies in solution is discussed.

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