1. Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper
- Author
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Evelijn Lourijsen, Mika J. Mäkelä, Ludger Klimek, Ralph Mösges, Wytske Fokkens, Sanna Toppila-Salmi, Valérie Hox, Kristian Aasbjerg, Thibaut Van Zele, Philippe Gevaert, Claus Bachert, Joaquim Mullol, Koen Boussery, Arnout Jordens, Sophie Scheire, Paloma Campo, P. V. Tomazic, Laura Pujols, Martin Wagemann, Ioana Agache, Isam Alobid, Job F M van Boven, Michael Rudenko, Carmen Rondon, Claire Hopkins, Glenis Scadding, Peter Hellings, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, and UCL - (SLuc) Service d'oto-rhino-laryngologie
- Subjects
Rhinology ,medical literature ,evidence based medicine ,Rhinosinusitis ,adverse event ,gastrointestinal symptom ,otorhinolaryngology ,eye disease ,nose polyp ,Systemic therapy ,mental disease ,systemic therapy ,DOUBLE-BLIND ,0302 clinical medicine ,cardiovascular disease ,ORAL STEROIDS ,lipid metabolism ,Medicine and Health Sciences ,SEVERE NASAL POLYPOSIS ,Cushingoid syndrome ,Immunology and Allergy ,030223 otorhinolaryngology ,Rinitis ,Rhinitis ,acute rhinosinusitis ,alternative medicine ,drug effect ,CORTICOSTEROID-THERAPY ,immunosuppressive treatment ,nose disease ,Glucocorticosteroids ,risk benefit analysis ,3. Good health ,ALLERGIC RHINITIS ,priority journal ,protein metabolism ,SEASONAL ,diabetes mellitus ,drug induced disease ,endocrine disease ,BONE-MINERAL DENSITY ,ENDOSCOPIC SINUS SURGERY ,pediatric patient ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,hypothalamus hypophysis adrenal system ,injection site discomfort ,Immunology ,drug cost ,desensitization ,review ,autoimmune disease ,fungal sinusitis ,03 medical and health sciences ,WEGENERS-GRANULOMATOSIS ,drug activity ,short course therapy ,medicine ,drug mechanism ,carbohydrate metabolism ,human ,Intensive care medicine ,Glucocorticoides ,Glucocorticoids ,avascular necrosis ,peptic ulcer ,Asthma ,drug use ,long term care ,allergic rhinitis ,calcium balance ,business.industry ,hypophysis disease ,chronic rhinosinusitis ,antiinflammatory activity ,Evidence-based medicine ,RC581-607 ,asthma ,medicine.disease ,osteoporosis ,infection ,Review article ,RHEUMATOID-ARTHRITIS ,drug efficacy ,Upper respiratory tract infection ,030228 respiratory system ,hypothalamus disease ,upper respiratory tract infection ,occupational disease ,glucocorticoid ,GLUCOCORTICOID-RECEPTOR-ALPHA ,hyperglycemia ,Immunologic diseases. Allergy ,Airway ,business ,Medical literature - Abstract
Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that-potentially severe-side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease. ispartof: CLINICAL AND TRANSLATIONAL ALLERGY vol:10 issue:1 ispartof: location:England status: published
- Published
- 2019