1. Coagulase-negative staphylococcal prosthetic valve endocarditis--a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study
- Author
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Chu, V. H., Miro, J. M., Hoen, B., Cabel, C. H., Pappa, P. A., Jones, P., Stryjewski, M. E., Anguera, I., Braun, S., Muñ, oz, P., Commerford, P., Tornos, P., Francis, J., Oyonarte, M., Selton-Suty, C., Morris, A. J., Habib, G., Almirante, B., Sexton, D. J., Corey, G. R., Fowler, V. G. Jr, International Collaboration on Endocarditis-Prospective Cohort Study Group Investigators: Baršić, Bruno et al., Chu, Vh, Miro, Jm, Hoen, B, Cabell, Ch, Pappas, Pa, Jones, P, Stryjewski, Me, Anguera, I, Braun, S, Muñoz, P, Commerford, P, Tornos, P, Francis, J, Oyonarte, M, Selton Suty, C, Morris, Aj, Habib, G, Almirante, B, Sexton, Dj, Corey, Gr, Fowler VG, Jr, among International Collaboration on Endocarditis Prospective Cohort Study Group, Investigator, Utili, Riccardo, Service des maladies infectieuses et tropicales, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Hôpital Saint-Jacques, Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Department of Physics [Jyväskylä Univ] (JYU), University of Jyväskylä (JYU), Service de cardiologie, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Hôpital Saint-Jacques, Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Department of Physics, University of Jyvaskyl ( University of Jyvaskyl ), University of Jyvaskyl, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille ( APHM ) - Hôpital de la Timone [CHU - APHM] ( TIMONE ), AII - Amsterdam institute for Infection and Immunity, Infectious diseases, and Laboratoire Chrono-environnement (UMR 6249) (LCE)
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Male ,Time Factors ,MESH: Drug Resistance, Microbial ,MESH : Aged ,MESH : Prospective Studies ,MESH : Coagulase ,030204 cardiovascular system & hematology ,Postoperative Complications ,0302 clinical medicine ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,MESH: Postoperative Complications ,MESH: Staphylococcus aureus ,MESH : Female ,Hospital Mortality ,Prospective Studies ,030212 general & internal medicine ,MESH : Endocarditis, Bacterial ,Abscess ,Prospective cohort study ,MESH: Aged ,Cross Infection ,MESH: Statistics, Nonparametric ,MESH: Middle Aged ,biology ,MESH : Staphylococcus aureus ,valvular heart disease ,cons ,Drug Resistance, Microbial ,coagulase-negative staphylococci ,endoccarditis ,prosthetic valves ,Middle Aged ,Staphylococcal Infections ,3. Good health ,[ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Heart Valve Prosthesis ,Infective endocarditis ,Female ,MESH: Coagulase ,Cardiology and Cardiovascular Medicine ,MESH : Cross Infection ,Cohort study ,MESH : Time Factors ,Coagulase ,Staphylococcus aureus ,medicine.medical_specialty ,Prosthesis-Related Infections ,MESH: Heart Valve Prosthesis ,MESH : Male ,MESH: Staphylococcal Infections ,MESH : Bioprosthesis ,Statistics, Nonparametric ,MESH : Prosthesis-Related Infections ,MESH : Heart Valve Prosthesis ,MESH : Hospital Mortality ,03 medical and health sciences ,MESH : Drug Resistance, Microbial ,medicine ,Humans ,Endocarditis ,MESH : Middle Aged ,MESH: Endocarditis, Bacterial ,MESH: Hospital Mortality ,MESH : Statistics, Nonparametric ,Aged ,Bioprosthesis ,MESH: Humans ,business.industry ,MESH: Prosthesis-Related Infections ,MESH : Humans ,MESH: Time Factors ,MESH: Cross Infection ,Endocarditis, Bacterial ,medicine.disease ,biology.organism_classification ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,MESH: Male ,MESH: Prospective Studies ,Surgery ,MESH: Bioprosthesis ,Viridans streptococci ,MESH : Postoperative Complications ,MESH : Staphylococcal Infections ,business ,MESH: Female - Abstract
International audience; OBJECTIVE: To describe the contemporary features of coagulase-negative staphylococcal (CoNS) prosthetic valve endocarditis (PVE). DESIGN: Observational study of prospectively collected data from a multinational cohort of patients with infective endocarditis. Patients with CoNS PVE were compared to patients with Staphylococcus aureus and viridans streptococcal (VGS) PVE. SETTING: The International Collaboration on Endocarditis-Prospective Cohort Study (ICE-PCS) is a contemporary cohort of patients with infective endocarditis from 61 centres in 28 countries. PATIENTS: Adult patients in the ICE-PCS with definite PVE and no history of injecting drug use from June 2000 to August 2005 were included. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Heart failure, intracardiac abscess, death. RESULTS: CoNS caused 16% (n = 86) of 537 cases of definite non-injecting drug use-associated PVE. Nearly one-half (n = 33/69, 48%) of patients with CoNS PVE presented between 60 days and 365 days of valve implantation. The rate of intracardiac abscess was significantly higher in patients with CoNS PVE (38%) than in patients with either S aureus (23%, p = 0.03) or VGS (20%, p = 0.05) PVE. The rate of abscess was particularly high in early (50%) and intermediate (52%) CoNS PVE. In-hospital mortality was 24% for CoNS PVE, 36% for S aureus PVE (p = 0.09) and 9.1% for VGS PVE (p = 0.08). Meticillin resistance was present in 68% of CoNS strains. CONCLUSIONS: Nearly one-half of CoNS PVE cases occur between 60 days and 365 days of prosthetic valve implantation. CoNS PVE is associated with a high rate of meticillin resistance and significant valvular complications.
- Published
- 2009