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Start Over Author "Lee, Cheng-Lin" Topic cancer cells
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1. Design, syntheses, and biological evaluations of squamostolide and its related analogs

Author

Lee, Cheng-Lin, Lin, Chi-Fong, Lin, Wan-Ru, Wang, Kun-Sheng, Chang, Ya-her, Lin, Shinne-Ren, Wu, Yang-Chang, and Wu, Ming-Jung

Subjects
*CANCER cells, *CELL culture, *CELL lines, *TUMORS
Abstract

Abstract: Squamostolide and its related analogs were designed and synthesized for biological evaluation. All these compounds were tested for growth inhibition activities against human tumor cell lines, in which one of the compounds showed the most potent cytotoxicity among these derivatives against a full panel of 60 human cancer cell lines. The same compound also showed G2/M phase arrest and a weak apoptotic effect during flow cytometric analysis. [Copyright &y& Elsevier]

Published
2005
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