1. The interobserver agreement in the detection of recurrent HNSCC using MRI including diffusion weighted MRI.
- Author
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Peltenburg B, Driessen JP, Philippens MEP, Pameijer FA, Castelijns J, Dankbaar JW, Dorgelo B, Lange CAH, Meijer FJA, Palm WM, Roosendaal SD, Steens SCA, Verbist BM, Stegeman I, Janssen LM, de Bree R, and Terhaard CHJ
- Subjects
- Aged, Diffusion Magnetic Resonance Imaging methods, Female, Humans, Magnetic Resonance Imaging methods, Male, Middle Aged, Observer Variation, Prospective Studies, Reference Standards, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell pathology, Head and Neck Neoplasms pathology, Neoplasm Recurrence, Local pathology
- Abstract
Introduction: For the detection of local recurrences of head and neck squamous cell carcinomas (HNSCC) after (chemo)radiation, diagnostic imaging is generally performed. Diffusion weighted magnetic resonance imaging (DW-MRI) has been proven to be able to adequately diagnose the presence of cancer. However evaluation of DW-MR images for recurrences is difficult and could be subject to individual interpretation., Aim: To determine the interobserver agreement, intraobserver agreement and influence of experience of radiologists in the assessment of DW-MRI in patients clinically suspected of local recurrent HNSCC after (chemo)radiation., Methods: Ten experienced head and neck radiologists assessed follow-up MRI including DW-MRI series of 10 patients for the existence of local recurrence on a two point decision scale (local recurrence or local control). Patients were clinically suspected for a recurrence of laryngeal (n = 3), hypopharyngeal (n = 3) or oropharyngeal (n = 4) cancer after (chemo)radiation with curative intent. Fleiss' and Cohen's Kappa were used to determine interobserver agreement and intraobserver agreement, respectively., Results: Interobserver agreement was κ = 0.55. Intraobserver agreement was κ = 0.80. Prior experience within the field of radiology and with DW-MRI had no significant influence on the scoring., Conclusion: For the assessment of HNSCC recurrence after (chemo)radiation by DW-MRI, moderate interobserver agreement and substantial intraobserver agreement was found., (Copyright © 2018 Elsevier B.V. All rights reserved.)
- Published
- 2018
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