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The selective construction of a diverse array of five-membered aromatic heterocycles from common starting materials is an attractive and challenging task. We report here that 5-alkylthio-pyrroles, 4-alkylthiocarbonyl-pyrroles and 2-alkylthio-4-tosyl-furans can be prepared, selectively, in a single operation using the readily available α-formyl ketene dithioacetals as common precursors, through their regiodivergent heterocyclization with α-acidic isocyanides controlled by the choice of suitable catalysts/promoters. [ABSTRACT FROM AUTHOR]

A new strategy, the 1,3-carbothiolation/aromatization, for the synthesis of functionalized (trifluoromethyl)arenes has been developed that enables the regioselective introduction of two different functional groups onto an “aromatic ring” in the meta-position to each other in a single step. [ABSTRACT FROM AUTHOR]

The reaction of dithioacetals (I) with nitriles (II) followed by a zinc-mediated one-pot reaction of the isolable intermediate (V) leads to 5-ethylthiopyrroles (III), whilst the copper-mediated reaction of the intermediate (V) affords 4-ethylthiocarbonylpyrroles (IV) via a second isolable intermediate (VI). [ABSTRACT FROM AUTHOR]

A tandem formal [3+2] cycloaddition/cyclization reaction of aminochalcones with tosylmethyl isocyanide derivatives was developed for the practical and convenient synthesis of diverse tricyclic pyrrolo[3,4- c]quinolines in high to excellent yields. In this domino process, three new bonds and two rings are successively formed at ambient conditions. [ABSTRACT FROM AUTHOR]

Abstract: Monodisperse Fe3O4@silica core–shell microspheres have been successfully prepared by using a two step method. Due to their exceptional properties, these composite microspheres can be removed conveniently from water via an external magnet. These composite microspheres can be applied to remove heavy metal ions from industrial wastewater because the surface of the microspheres is covered with SiO2, and the SiO2 is inactive and can adsorb heavy metal ions (such as Hg2+, Pb2+). Furthermore, the interaction between SiO2 and heavy metal ions is reversible, which means that the adsorbed ions can be removed from SiO2 in weak acidic deionized water with the assistance of ultrasound radiation. It is noteworthy that the adsorption ability of the composite microspheres is so strong that any further modification of the composite microspheres is unnecessary. On the basis of the above points, we consider that the synthesized Fe3O4@silica composite microspheres can be used as a useful recyclable tool for heavy metal ion removal. This work provides a potential and unique technique for heavy metal ion removal from industrial wastewater. [Copyright &y& Elsevier]

The article presents a chemical reaction of direct synthesis of the pyrrole [3,4-c] quinolines by using the domino reaction of tosylmethyl isocyanides and aminochalcones.

The base-promoted reaction of cyclic enediones with isocyanides (II) leads to 7- and 8-membered-ring fused pyrroles (III) in moderate yields. [ABSTRACT FROM AUTHOR]