413 results on '"Hao, Peng"'
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2. Essential role of momentum-forbidden dark excitons in the energy transfer responses of monolayer transition-metal dichalcogenides
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Jhen-Dong Lin, Ping-Yuan Lo, Guan-Hao Peng, Wei-Hua Li, Shiang-Yu Huang, Guang-Yin Chen, and Shun-Jen Cheng
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Materials of engineering and construction. Mechanics of materials ,TA401-492 ,Chemistry ,QD1-999 - Abstract
Abstract We present a theoretical investigation of exciton-mediated Förster resonant energy transfers (FRET’s) from photoexcited quantum dots (QD’s) to transition-metal dichalcogenide monolayers (TMD-ML’s), implemented by the quantum theory of FRET on the base of first-principles-calculated exciton fine structures. With the enhanced electron-hole Coulomb interactions, atomically thin TMD-MLs are shown to serve as an exceptional platform for FRET that are mediated purely by excitons and take full advantage of the superior excitonic properties. Remarkably, the energy-transfer responses of atomically thin TMD-ML’s are shown to be dictated by the momentum-forbidden dark excitons rather than the commonly recognized bright ones. Specifically, the longitudinal dark exciton states following the exchange-driven light-like linear band dispersion play a key role in grading up the efficiency and robustness of FRET of TMD-ML against the inhomogeneity of QD-donor ensembles. With the essential involvement of dark excitons, the FRET responses of TMD-ML’s no longer follow the distance power law as classically predicted and, notably, cannot manifest the dimensionality of the donor-acceptor system.
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- 2023
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3. YOLO-Chili: An Efficient Lightweight Network Model for Localization of Pepper Picking in Complex Environments
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Hailin Chen, Ruofan Zhang, Jialiang Peng, Hao Peng, Wenwu Hu, Yi Wang, and Ping Jiang
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chili detection ,automatic picking ,neural network ,model compression ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Currently, few deep models are applied to pepper-picking detection, and existing generalized neural networks face issues such as large model parameters, prolonged training times, and low accuracy. To address these challenges, this paper proposes the YOLO-chili target detection algorithm for chili pepper detection. Initially, the classical target detection algorithm YOLOv5 serves as the benchmark model. We introduce an adaptive spatial feature pyramid structure that combines the attention mechanism and the concept of multi-scale prediction to enhance the model’s detection capabilities for occluded and small target peppers. Subsequently, we incorporate a three-channel attention mechanism module to improve the algorithm’s long-distance recognition ability and reduce interference from redundant objects. Finally, we employ a quantized pruning method to reduce model parameters and achieve lightweight processing. Applying this method to our custom chili pepper dataset, we achieve an average precision (AP) value of 93.11% for chili pepper detection, with an accuracy rate of 93.51% and a recall rate of 92.55%. The experimental results demonstrate that YOLO-chili enables accurate and real-time pepper detection in complex orchard environments.
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- 2024
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4. Species Diversity, Nitrogen Fixation, and Nutrient Solubilization Activities of Endophytic Bacteria in Pea Embryos
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Junjie Hao, Xiaoyan Zhang, Shizuo Qiu, Fengjing Song, Xianghua Lyu, Yu Ma, and Hao Peng
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bacterial diversity ,edible peas ,plant embryo microbiome ,endophytic bacteria ,nitrogen-fixing bacteria ,plant growth-promoting bacteria ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Endophytic bacteria, especially those that participate in nitrogen fixation, play critical roles in supplying essential nutrients for legume plant growth. Despite that there have been numerous investigations targeting bacterial microbiomes in legume roots and nodules, little is known about embryonic bacteria that facilitate plant nutrient utilization after seed germination. Here, we collected and investigated endophytic bacterial microbiome in edible pea (Pisum sativum) embryos using five representative cultivars and a pea sprout (shoot of pea [SHP]) control. Twenty-six nitrogen-fixing bacteria (NFB) were isolated from pea embryos, with three strains found in fresh grain pea (FGP) and snow pea (SP) exhibiting the strongest nitrogenase activity of above 85 nmol C2H4/mL/h. Some NFB isolates are also potassium-solubilizing bacteria (KSB) or phosphorus-solubilizing bacteria (PSB) utilizing inorganic and/or organic phosphorus. All 26 NFB showed variable levels (0.41 to 7.10 μg/mL) of indole-3-acetic acid (IAA) secretion. The nutrient-solubilizing NFB identified in our research are potential targets for biofertilizer development. They could be useful in converting nitrogen, potassium, and/or phosphorus into usable forms for the plants. At the microbiome level, high-throughput 16S ribosomal RNA (rRNA) sequencing of 40 bacterial collections from pea embryos generated 4234 operational taxonomic units (OTUs) using 97% identity as the threshold for clustering high-quality effective reads (valid tags). Analysis of OTU annotation results revealed similar species community structures, abundance, and diversity in most samples. Our embryo-derived endophytic bacterial pool provides a microbiome platform for seed dormancy and germination research of edible peas, as well as for digging new biofertilizer resources in general.
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- 2024
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5. Study of Estimated Ultimate Recovery Prediction and Multi-Stage Supercharging Technology for Shale Gas Wells
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Yanli Luo, Jianying Yang, Man Chen, Liu Yang, Hao Peng, Jinyuan Liang, and Liming Zhang
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shale gas ,multi-stage supercharging ,EUR ,steady yield increase ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The development of shale gas reservoirs often involves the utilization of horizontal well segmental multi-stage fracturing techniques. However, these reservoirs face challenges, such as rapid initial wellhead pressure and production decline, leading to extended periods of low-pressure production. To address these issues and enhance the production during the low-pressure stage, pressurized mining is considered as an effective measure. Determining the appropriate pressurization target and method for the shale gas wells is of great practical significance for ensuring stable production in shale gas fields. This study takes into account the current development status of shale gas fields and proposes a three-stage pressurization process. The process involves primary supercharging at the center station of the block, secondary supercharging at the gas collecting station, and the introduction of a small booster device located behind the platform separator and in front of the outbound valve group. By incorporating a compressor, the wellhead pressure can be reduced to 0.4 MPa, resulting in a daily output of 12,000 to 14,000 cubic meters from the platform. Using a critical liquid-carrying model for shale gas horizontal wells, this study demonstrates that reducing the wellhead pressure decreases the critical flow of liquid, thereby facilitating the discharge of the accumulated fluid from the gas well. Additionally, the formation pressure of shale gas wells is estimated using the mass balance method. This study calculates the cumulative production of different IPR curves based on the formation pressure. It develops a dynamic production decline model for gas outlet wells and establishes a relationship between the pressure depletion of gas reservoirs and the cumulative gas production before and after pressurization of H10 −2 and H10 −3 wells. The final estimated ultimate recovery of two wells is calculated. In conclusion, the implementation of multi-stage pressurization, as proposed in this study, effectively enhances the production of, and holds practical significance for, stable development of shale gas fields.
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- 2023
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6. Novel Technology for Vanadium and Chromium Extraction with KMnO4 in an Alkaline Medium
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Hao Peng, Jing Guo, Huisheng Huang, Bing Li, and Xingran Zhang
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Chemistry ,QD1-999 - Published
- 2021
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7. Thermodynamic and Kinetic Studies on Adsorption of Vanadium with Glutamic Acid
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Hao Peng, Hongzhi Qiu, Caiqiong Wang, Binfang Yuan, Huisheng Huang, and Bing Li
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Chemistry ,QD1-999 - Published
- 2021
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8. A Model-Based Intelligent Adjustment Method of Toolface for Bent-Housing Motor
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Tiansheng Deng, Qian Li, Hu Yin, and Hao Peng
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artificial intelligence ,toolface adjustment ,genetic algorithm ,BP neural network ,bent-housing motor ,directional well ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The traditional toolface adjustment of a bent-housing motor is time-consuming and laborious. For the goal of rapid and accurate toolface adjustment, this paper presents an intelligent toolface adjustment method based on the drill string dynamics model and the BP (back propagation) neural network, optimized by a GA (genetic algorithm). Firstly, for the mode of rotating the drill string at the wellhead to change the downhole toolface, the drill string dynamics model is used to calculate the toolface change value. Then, the actual toolface change value is taken as the output data; the calculated toolface change value and the factors that have a significant impact on the change value of the toolface are taken as the input parameters; and the GA-BP neural network is adopted to fit the relationship between the input parameters and the output data. For the mode of changing the toolface by changing the WOB (weight on bit), the WOB change value and other parameters that cause the toolface to change were taken as the input data and the toolface change value was taken as the output data; the relationship between the WOB and the toolface was fitted with the GA-BP neural network. The results show that the prediction of absolute error under the mode of adjusting the toolface by rotating the drill string at the wellhead is within 10.9783°, and the prediction of absolute error under the mode of adjusting the toolface by changing the WOB is within 18.8833°. The intelligent models established under the two modes can meet the requirements of toolface control accuracy. Using the established intelligent prediction model, the toolface can be adjusted to the required value range at one time, which can improve drilling efficiency, and reduce labor intensity and the dependence on the experience of on-site personnel.
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- 2023
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9. The Key Role of Non-Local Screening in the Environment-Insensitive Exciton Fine Structures of Transition-Metal Dichalcogenide Monolayers
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Wei-Hua Li, Jhen-Dong Lin, Ping-Yuan Lo, Guan-Hao Peng, Ching-Yu Hei, Shao-Yu Chen, and Shun-Jen Cheng
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transition-metal dichalcogenide monolayer ,dark-exciton ,non-local Coulomb screening ,exciton fine structure ,WSe2 ,Chemistry ,QD1-999 - Abstract
In this work, we present a comprehensive theoretical and computational investigation of exciton fine structures of WSe2-monolayers, one of the best-known two-dimensional (2D) transition-metal dichalcogenides (TMDs), in various dielectric-layered environments by solving the first-principles-based Bethe–Salpeter equation. While the physical and electronic properties of atomically thin nanomaterials are normally sensitive to the variation of the surrounding environment, our studies reveal that the influence of the dielectric environment on the exciton fine structures of TMD-MLs is surprisingly limited. We point out that the non-locality of Coulomb screening plays a key role in suppressing the dielectric environment factor and drastically shrinking the fine structure splittings between bright exciton (BX) states and various dark-exciton (DX) states of TMD-MLs. The intriguing non-locality of screening in 2D materials can be manifested by the measurable non-linear correlation between the BX-DX splittings and exciton-binding energies by varying the surrounding dielectric environments. The revealed environment-insensitive exciton fine structures of TMD-ML suggest the robustness of prospective dark-exciton-based optoelectronics against the inevitable variation of the inhomogeneous dielectric environment.
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- 2023
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10. pH-Responsive Pluronic F127–Lenvatinib-Encapsulated Halogenated Boron-Dipyrromethene Nanoparticles for Combined Photodynamic Therapy and Chemotherapy of Liver Cancer
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Jingjing Zong, Hao Peng, Xin Qing, Zhe Fan, Wenjing Xu, Xuanlong Du, Ruihua Shi, and Yewei Zhang
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Chemistry ,QD1-999 - Published
- 2021
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11. Leaching Kinetics of Vanadium from Calcium-Roasting High-Chromium Vanadium Slag Enhanced by Electric Field
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Hao Peng, Jing Guo, and Xingran Zhang
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Chemistry ,QD1-999 - Published
- 2020
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12. Oxidative Leaching Kinetics of Vanadium from the Vanadium-Chromium-Reducing Residue with K2Cr2O7
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Hao Peng, Qian Shang, Ronghua Chen, Yumeng Leng, Jing Guo, Zuohua Liu, and Changyuan Tao
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Chemistry ,QD1-999 - Published
- 2020
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13. Recovery and Separation of Vanadium and Chromium by Two-Step Alkaline Leaching Enhanced with an Electric Field and H2O2
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Hao Peng, Liu Yang, Ya Chen, Jing Guo, and Bing Li
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Chemistry ,QD1-999 - Published
- 2020
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14. Numerical Simulation and Experimental Study of a Multistage Multiphase Separation System
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Xuezhong Chen, Jian Zheng, Jiayu Jiang, Hao Peng, Yanli Luo, and Liming Zhang
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oil–water separation ,gravitational separation ,coalescing components ,separating efficiency ,oil droplet size ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Nowadays, most oilfields have entered the high water cut stage of waterflood development. The importance of oil–water separation technology becomes more obvious. Gravity separation is one of the most commonly used treatment techniques for produced fluid. The gravitational separator has a large processing capacity and a wide application range, but its structure is relatively simple and the separation efficiency gradually falls behind to meet current production needs. The key difficulties to improve the separation efficiency are to analyze the flow field and coalescing components inside the separator. Aiming at these difficulties, this paper reports an innovatively designed series-parallel multistage multiphase separation system (MMSS). A horizontal separator is connected in series with a vertical separator, and the vertical separator consists of five discrete pipes connected in parallel. Different coalescing components are then set inside the vertical separator. The separation effect of the MMSS is studied by numerical simulation and laboratory experiments. The oil phase volume distribution cloud diagrams of coalescing components are analyzed by numerical simulation, including semicircle baffle, spiral track plate, four-hole plate and seven-hole plate. Laboratory experiments show that MMSS has a high separation efficiency, and the water content at the oil outlet is 3.0% less than that of the horizontal separator. By observing the shape of oil droplets at the outlet and measuring the oil cut and water cut at the sampling outlet, the separation effect of four coalescent plates is obtained. According to the statistics, when the volumetric flow at the inlet of the separator is 1.5 m3/h, the average particle size of oil drops in the blank pipe, semicircular baffle, four-hole plate, spiral track and seven-hole plate increases in turn. A continuous oil layer appears at the outlet of the vertical separator in the fully open state. The water content at the oil outlet of the semicircular baffle coalescing component is always at a high level under different flow rates. When the inlet volumetric flow rate is less than 1.6 m3/h, the performance of the spiral track coalescing component is better. With the increase of the inlet volumetric flow rate, the separation efficiency of the spiral track is lower than that of the orifice. The results show that the semicircular coalescing component has the worst performance, the spiral track coalescing component is superior at small volumetric flow rates, and the orifice coalescing component is superior at large volumetric flow rates.
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- 2022
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15. Compact 15 mJ Fiber–Solid Hybrid Hundred-Picosecond Laser Source for Laser Ablation on Copper
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Tingting Wang, Jing Wang, Meng Zhao, Hao Peng, Jianwei Zhou, Guannan Qu, Yong Tan, and Hongxing Cai
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fiber–solid hybrid laser ,hundred-picosecond ,single-mode fiber stretcher ,depolarization compensation ,laser ablation ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
We report on a millijoule-level fiber–solid hybrid hundred-picosecond laser system with a stable performance and compact structure. The laser system is based on a master oscillator power amplifier structure containing an all-fiber master oscillator, a quasi-continuous-wave side-pumped Nd:YAG regenerative amplifier, and a double-pass amplifier. By using the filtering effect of fiber Bragg grating and the dispersion characteristics of single-mode fiber stretcher, the spectrum broadening caused by self-phase modulation effect is effectively suppressed. Thus, the gain linewidth of the Yb-doped fiber seed source and Nd:YAG laser amplifiers is accurately matched. The reason for thermally induced depolarization in the solid-state laser amplifier is theoretically analyzed, and a more flexible depolarization compensation structure is adopted in amplifier experiment. Furthermore, the pulse energy of 14.58 mJ and pulse width of 228 ps is achieved at 500 Hz repetition rate. The central wavelength is 1064.1 nm with a 3 dB bandwidth of 0.47 nm. The beam quality factors in the horizontal and vertical directions are 1.49 and 1.51, respectively. This laser system has a simple and compact structure and has a power stability of 1.9%. The high pulse energy and beam quality of this hundred-picosecond laser are confirmed by latter theoretical simulation of copper laser ablation. It is a very practical laser system for material processing and laser-induced damage.
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- 2022
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16. Efficient Adsorption-Photocatalytic Removal of Tetracycline Hydrochloride over Octahedral MnS
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Jing Guo, Tingting Liu, Hao Peng, and Xiaogang Zheng
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MnS ,octahedral structure ,tetracycline hydrochloride ,adsorption-photocatalysis ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
To disclose the effect of crystal plane on the adsorption-photocatalytic activity of MnS, octahedral MnS was prepared via the hydrothermal route to enhance the adsorption and photocatalytic efficiencies of tetracycline hydrochloride (TCH) in visible light region. The optimal MnS treated at 433 K for 16 h could remove 94.83% TCH solution of 260 mg L−1 within 180 min, and its adsorption-photocatalytic efficiency declined to 89.68% after five cycles. Its excellent adsorption-photocatalytic activity and durability were ascribed to the sufficient vacant sites of octahedral structure for TCH adsorption and the feasible band-gap structure for visible-light response. In addition, the band gap structure (1.37 eV) of MnS with a conduction band value of −0.58 eV and a valence band value of 0.79 eV was favorable for the generation of O2−, while unsuitable for the formation of OH. Hence, octahedral MnS was a potential material for the removal of antibiotics from wastewater.
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- 2022
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17. Highly Efficient Recovery of Vanadium and Chromium: Optimized by Response Surface Methodology
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Hao Peng, Feng Wang, Gang Li, Jing Guo, and Bing Li
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Chemistry ,QD1-999 - Published
- 2019
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18. Functions of COP1/SPA E3 Ubiquitin Ligase Mediated by MpCRY in the Liverwort Marchantia polymorpha under Blue Light
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Li Zhang, Tianhong Li, Shengzhong Su, Hao Peng, Sudi Li, Ke Li, Luyao Ji, Yaoyun Xing, Junchuan Zhang, Xinglin Du, Mingdi Bian, Yuying Liao, Zhenming Yang, and Zecheng Zuo
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blue light ,Marchantia polymorpha ,cryptochromes ,COP1/SPA complex ,HY5 ,ubiquitination ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
COP1/SPA1 complex in Arabidopsis inhibits photomorphogenesis through the ubiquitination of multiple photo-responsive transcription factors in darkness, but such inhibiting function of COP1/SPA1 complex would be suppressed by cryptochromes in blue light. Extensive studies have been conducted on these mechanisms in Arabidopsis whereas little attention has been focused on whether another branch of land plants bryophyte utilizes this blue-light regulatory pathway. To study this problem, we conducted a study in the liverwort Marchantia polymorpha and obtained a MpSPA knock-out mutant, in which Mpspa exhibits the phenotype of an increased percentage of individuals with asymmetrical thallus growth, similar to MpCRY knock-out mutant. We also verified interactions of MpSPA with MpCRY (in a blue light-independent way) and with MpCOP1. Concomitantly, both MpSPA and MpCOP1 could interact with MpHY5, and MpSPA can promote MpCOP1 to ubiquitinate MpHY5 but MpCRY does not regulate the ubiquitination of MpHY5 by MpCOP1/MpSPA complex. These data suggest that COP1/SPA ubiquitinating HY5 is conserved in Marchantia polymorpha, but dissimilar to CRY in Arabidopsis, MpCRY is not an inhibitor of this process under blue light.
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- 2021
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19. A Nano-In-Micro System for Enhanced Stem Cell Therapy of Ischemic Diseases
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Hai Wang, Pranay Agarwal, Yichao Xiao, Hao Peng, Shuting Zhao, Xuanyou Liu, Shenghua Zhou, Jianrong Li, Zhenguo Liu, and Xiaoming He
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Chemistry ,QD1-999 - Published
- 2017
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20. Efficient solar-light photocatalytic H2 evolution of Mn0.5Cd0.5S coupling with S,N-codoped carbon
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Hao Peng, Congying Huang, Xiaogang Zheng, and Jing Wen
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Photon ,Materials science ,business.industry ,General Chemical Engineering ,Quantum yield ,chemistry.chemical_element ,Renewable energy ,Chemical engineering ,chemistry ,Hydrogen economy ,Photocatalysis ,Water splitting ,business ,Carbon ,Visible spectrum - Abstract
The low-cost and highly-efficient photocatalysts for solar-light induced water splitting had drawn great attention to develop the renewable hydrogen economy. To enhance the solar-light driven H2 evolution of Mn0.5Cd0.5S, Mn0.5Cd0.5S was modified by S,N-codoped carbon (3-MCS/SN-C) via the in-situ sulfurization at high temperature. In contrast with Mn0.5Cd0.5S (11.13 mmol g-1 h-1) and S-doped g-C3N4 (0.35 mmol g-1 h-1), the optimal 3-MCS/SN-C with a mass ratio of Mn0.5Cd0.5S to S,N-codoped carbon of 1:3 exhibited the best H2 evolution rate of 27.58 mmol g-1 h-1 and an apparent quantum yield of 27.43% at 400 nm. The photo-corrosion induced to the decreased H2 evolution capacity of 3-MCS/SN-C from 131.13 to 126.52 mmol g-1 after five cycles of 5 h. S,N-codoped carbon could efficiently capture visible light and absorb the photons, leading to the efficient transformation and separation of photo-generated carriers at the junction interface between Mn0.5Cd0.5S and S,N-codoped carbon.
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- 2022
21. Novel Technology for Vanadium and Chromium Extraction with KMnO4 in an Alkaline Medium
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Jing Guo, Hao Peng, Xingran Zhang, Huisheng Huang, and Bing Li
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Reaction conditions ,Residue (complex analysis) ,Solid product ,Chemistry ,General Chemical Engineering ,Extraction (chemistry) ,Surface chemical reaction ,Kinetics ,Vanadium ,chemistry.chemical_element ,General Chemistry ,Article ,Chromium ,QD1-999 ,Nuclear chemistry - Abstract
This paper focused on the oxidation–alkaline extraction process of vanadium–chromium–reducing residue. The affected parameters including reaction temperature, KMnO4 dosage, reaction time, NaOH dosage, and liquid-to-solid ratio on the extraction process were investigated. The E–pH diagram and the thermodynamic analysis indicated that KMnO4 was suitable for the oxidation of low-valence vanadium and chromium. Vanadium (97.24%) and chromium (56.20%) were extracted under the following optimal reaction conditions: reaction temperature of 90 °C, reaction time of 90 min, dosage of KMnO4 at m(KMnO4)/m(residue) = 0.40, dosage of NaOH at m(NaOH)/m(residue) = 0.30, and liquid-to-solid ratio at 5:1 mL/g. The extraction process of vanadium was controlled by the reactant through the solid product layer and the extraction kinetics behavior fitted well with the shrink core model with an Ea of 15.37 kJ/mol. At the same time, the surface chemical reaction was the controlling step for chromium extraction, which was difficult with an Ea of 39.78 kJ/mol.
- Published
- 2021
22. Microscopic pore-fracture configuration and gas-filled mechanism of shale reservoirs in the western Chongqing area, Sichuan Basin, China
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Zhanlei Wang, Shaoguang Ma, Yonghong Fu, Qinhong Hu, Zhi'an Lei, Hao Peng, Yifan Gu, Dazhong Dong, Zimeng Wang, Yuqiang Jiang, and Xingping Yin
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Energy Engineering and Power Technology ,Mineralogy ,Geochemistry and Petrology ,Natural gas ,quality parameter ,gas bearing characteristics ,Organic matter ,Petroleum refining. Petroleum products ,Porosity ,chemistry.chemical_classification ,business.industry ,shale reservoir ,shale gas ,Geology ,Geotechnical Engineering and Engineering Geology ,Upper Ordovician Wufeng Formation ,Permeability (earth sciences) ,Hydrocarbon ,chemistry ,microscopic pore-fracture configuration ,Fracture (geology) ,Economic Geology ,Wetting ,business ,Oil shale ,TP690-692.5 - Abstract
Taking the Upper Ordovician Wufeng Formation to Lower Silurian Longmaxi Formation shale reservoirs in western Chongqing area as the study target, the argon ion polishing scanning electron microscope and nuclear magnetic resonance (NMR) experiments of different saturated wetting media were carried out. Based on the image processing technology and the results of gas desorption, the pore-fracture configuration of the shale reservoirs and its influence on gas-filled mechanism were analyzed. (1) The reservoir space includes organic pores, inorganic pores and micro-fractures and there are obvious differences between wells in the development characteristics of micro-fractures; the organic pores adjacent to the micro-fractures are poorly developed, while the inorganic pores are well preserved. (2) According to the type, development degree and contact relationship of organic pore and micro-fracture, the pore-fracture configuration of the shale reservoir is divided into four types. (3) Based on the differences in NMR T2 spectra of shale samples saturated with oil and water, an evaluation parameter of pore-fracture configuration was constructed and calculated. The smaller the parameter, the better the pore-fracture configuration is. (4) The shale reservoir with good pore-fracture configuration has well-developed organic pores, high porosity, high permeability and high gas content, while the shale reservoir with poor pore-fracture configuration has micro-fractures developed, which improves the natural gas conductivity and leads to low porosity and gas content of the reservoir. (5) Based on pore-fracture configuration, from the perspective of organic matter generating hydrocarbon, micro-fracture providing migration channel, three types of micro gas-filled models of shale gas were established.
- Published
- 2021
23. Nanosecond Laser Ablation of Ti–6Al–4V under Different Temperature
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Jiantao Zhao, Zhenge Zhu, Yacheng Xu, Xueyong Song, Yufan Wang, Hao Peng, Ying Wang, Jinrong Zuo, Xuedao Shu, and Anmin Yin
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nanosecond laser ablation ,multi-pulse irradiation ,Ti–6Al–4V ,substrate temperature ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Multi-pulse nanosecond laser ablation of Ti–6Al–4V is a complex process. In this study, the effect of substrate temperature on the nanosecond laser ablation of Ti–6Al–4V was investigated. Morphology, diameter and depth of ablation craters were observed; ablation efficiency ω (μm3/mJ) was proposed to analyzes the ablation process. The results showed that, with the increasing of substrate temperature, the ablation craters’ diameter increased and depth decreased, while ω initially increased, but then decreased rapidly. Furthermore, with increasing pulse number, the depth of ablation crater increased linearly, while the growth of the diameter gradually slowed down and tended to be stable after the 16th irradiation. The above changes were different in details at different substrate temperatures.
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- 2020
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24. A Novel Technology for Recovery and Separation of Vanadium and Chromium from Vanadium-Chromium Reducing Residue
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Hao Peng, Liu Yang, Ya Chen, and Jing Guo
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vanadium ,chromium ,mno2 ,acid leaching ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
This paper was to develop an efficient process for efficient recovery and separation of vanadium and chromium. The vanadium-chromium reducing residue was conducted by oxidation acidic leaching with MnO2, followed by selective adsorption of vanadium and precipitation of chromium, respectively. The results showed that 97.93% vanadium was leached out and then adsorbed by melamine at pH 1.8 at 90 °C for 60 min. Almost all chromium was leached out and efficiently recovered as Cr2O3. The leaching process was mainly controlled by surface chemical reaction, and its kinetic behaviors fitted well with the shrink core model. The apparent activation energy for vanadium and chromium leaching out wascalculated as 19.93 kJ·mol−1 and 21.26 kJ·mol−1, respectively.
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- 2019
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25. N-Doped Carbon-Coated ZnS with Sulfur-Vacancy Defect for Enhanced Photocatalytic Activity in the Visible Light Region
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Hao Peng, Daixin Liu, Xiaogang Zheng, and Xiaojin Fu
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zns ,sulfur-vacancy defect ,n-doped carbon ,visible-light harvesting ,Chemistry ,QD1-999 - Abstract
In this work, N-doped carbon-coated ZnS with a sulfur-vacancy defect (ZnS@N-C) was performed for the visible-light-driven photodegradation of tetracycline hydrochloride (TCH). The obtained ZnS@N-C exhibited enhanced photocatalytic activity compared with ZnS for TCH removal. Among these ZnS@N-C composites, ZnS@N-C-3 with N-doped content of 3.01% (100 nm) presented the best visible-light photocatalytic activity and superior long-term photocatalytic stability after five cycle times for TCH removal in the visible light region. This may be ascribed to the interface between the N-doped carbon shell and ZnS with a sulfur-vacancy defect for efficient charge transfer and the restrained recombination of charge carriers. Electron spin resonance (ESR) results indicate that the ·O2‒ radical plays a crucial role in the enhanced photocatalytic activity of ZnS@N-C-3.
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- 2019
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26. Combined steam explosion and optimized green-liquor pretreatments are effective for complete saccharification to maximize bioethanol production by reducing lignocellulose recalcitrance in one-year-old bamboo
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Yanting Wang, Qiaomei Yang, Yuqi Li, Hantian Wei, Hao Peng, Haiwen Lu, Hairong Gao, Dan Zhan, Mostafa M. EI-Sheekh, Liangcai Peng, Zhi Qi, Xinchun Lin, and Mahmoud M.A. Bakr
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Bamboo ,060102 archaeology ,Renewable Energy, Sustainability and the Environment ,Chemistry ,020209 energy ,food and beverages ,Biomass ,06 humanities and the arts ,02 engineering and technology ,Pulp and paper industry ,complex mixtures ,chemistry.chemical_compound ,Biofuel ,Bioenergy ,0202 electrical engineering, electronic engineering, information engineering ,Lignin ,Green liquor ,0601 history and archaeology ,Cellulose ,Steam explosion - Abstract
Bamboo is a fast-growing perennial plant rich at lignocellulose convertible for biofuels and biochemical production. Despite various physical and chemical pretreatments have been implemented for bamboo biomass utilization, it becomes essential to explore optimal technology for complete biomass saccharification to maximize bioethanol production in the desirable bamboo substrates. In this study, the steam explosion followed with optimized green-liquor pretreatments were conducted in different-year-old bamboo samples using response surface methodology. Compared to the older samples, the one-year-old bamboo (PhY1) showed a complete biomass enzymatic saccharification with hexoses yield of 100.0% (% cellulose), leading to the highest bioethanol yield of 20.3% (% dry biomass) achieved among all previously-reported bamboo processes. Notably, those combined pretreatments could not only cause an effective co-extraction of hemicellulose-lignin complexes, but also distinctively modify major wall polymer features (cellulose DP and accessibility, hemicellulosic Xyl/Ara and lignin S/G) for significantly reduced lignocellulose recalcitrance, which should lead to an integrated enhancement to biomass enzymatic saccharification in the PhY1 bamboo sample. Therefore, this study has demonstrated a powerful strategy for a green-like biomass process, providing an applicable technology to achieve maximum bioethanol production in bamboo and other lignin-rich bioenergy crops.
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- 2021
27. Effect of Autoclave Pretreatment on Biogas Production through Anaerobic Digestion of Green Algae
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Feng Ruizhe, Asad A. Zaidi, Hao Peng, Yue Shi, and QiaoYan Li
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Anaerobic digestion ,biology ,Chemistry ,General Chemical Engineering ,Green algae ,biology.organism_classification ,Pulp and paper industry ,Biogas production ,Autoclave - Abstract
Anaerobic Digestion (AD) is one of the most widely used methods in the field of sustainable bioenergy production from various feedstock. One such feedstock is algae waste which has become an increasingly serious environmental problem. AD of algal biomass is hindered by the presence of resistant cell walls; hence a pretreatment step is usually required to decompose the cell wall structure. This study uses green algae (Enteromorpha) and anaerobic sludge as raw materials to explore the impact of autoclave (AC) pretreatment on biogas production. AC pretreatment was performed at 120 °C and 80 °C. The cumulative biogas production of the 120 °C AC pretreatment, 80 °C AC pretreatment and control group were 600 mL, 450 mL and 400 mL, respectively. The results showed that AC pretreatment improved the biodegradability of biomass as 120 °C AC pretreatment group achieved higher degradation rate of cells (95.99 %). The energy evaluation showed that the net energy ratio of the 120 °C AC pretreatment group was 1.07, indicating high overall energy gain via AD process. The experimental data is further modeled by using Modified Gompertz Model (MGM) and Logistic Function Model (LFM). To check the applicability of better model for this AD process, an Akaike Information Criteria (AIC) test was performed. AIC showed that the MGM is basically consistent with the experimental data and more reliable for prediction modeling of Enteromorpha AD.
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- 2021
28. Distinct Miscanthus lignocellulose improves fungus secreting cellulases and xylanases for consistently enhanced biomass saccharification of diverse bioenergy crops
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Qian Li, Yuqi Li, Peng Liu, Qiuming Cai, Ao Li, Liangcai Peng, Youmei Wang, Tao Xia, Yanting Wang, Haizhong Yu, Ran Zhang, Yuanyuan Tu, Hao Peng, and Xiaoyang Wei
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Arabinose ,060102 archaeology ,biology ,Renewable Energy, Sustainability and the Environment ,020209 energy ,food and beverages ,Biomass ,06 humanities and the arts ,02 engineering and technology ,Miscanthus ,Cellulase ,biology.organism_classification ,Pulp and paper industry ,chemistry.chemical_compound ,chemistry ,Biofuel ,Bioenergy ,0202 electrical engineering, electronic engineering, information engineering ,biology.protein ,Lignin ,0601 history and archaeology ,Hemicellulose - Abstract
Bioenergy crops provide enormous renewable biomass resources convertible for biofuel production, but lignocellulose recalcitrance fundamentally determines its enzymatic saccharification at high cost and low efficiency. In this study, total 30 diverse Miscanthus lignocellulose substrates were incubated with T. reesei strain to secret lignocellulose-degradation enzymes, and their major wall polymers features (cellulose crystallinity, hemicellulose arabinose and lignin H-monomer) were meanwhile examined with distinct impacts on the enzyme activities. Using characteristic Miscanthus (Msi62) de-lignin residue as inducing substrate with the reesei strain, this study detected that the Msi62-induced enzymes were of consistently higher enhancements on enzymatic saccharification of various lignocellulose residues examined in 17 grassy and woody bioenergy crops, particularly for the hemicellulose hydrolyses, compared to other two reesei-secreted cellulases and three commercial enzymes. Notably, based on SDS-gel protein separation profiling and LC-MS/MS analysis, the Msi62-induced enzymes consist of distinct cellulases (CBHI, BG, EGII) compositions and high-activity xylanases. Therefore, this study has demonstrated an applicable approach to achieve the optimal cellulases and xylanases cocktails that enable for low-costly and high-efficient enzymatic saccharification of diverse lignocellulose sources, providing a potential strategy for large-scale biofuel production in all major bioenergy crops.
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- 2021
29. Chiral Bidentate Phosphoramidite-Pd Catalyzed Asymmetric Decarboxylative Dipolar Cycloaddition for Multistereogenic Tetrahydrofurans with Cyclic N-Sulfonyl Ketimine Moieties
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Hao-Peng Lv, Zheng Wang, Hao-Di Yang, Xing-Wang Wang, Bai-Lin Wang, and Xiao-Peng Yang
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Sulfonyl ,chemistry.chemical_classification ,Isothiazole ,Phosphoramidite ,Denticity ,010405 organic chemistry ,Chemistry ,Organic Chemistry ,010402 general chemistry ,01 natural sciences ,Biochemistry ,Medicinal chemistry ,Cycloaddition ,0104 chemical sciences ,Catalysis ,chemistry.chemical_compound ,Physical and Theoretical Chemistry - Abstract
An asymmetric [3 + 2] cycloaddition of vinyl ethylenecarbonates (VECs) and (E)-3-arylvinyl substituted benzo[d] isothiazole 1,1-dioxides has been developed using the Pd complex of a bidentate phosphoramidite (Me-BIPAM) as the catalyst, providing a wide variety of chiral multistereogenic vinyltetrahydrofurans in good yields with excellent diastereo- and enantioselectivities (up to >20:1 dr, 99% ee).
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- 2021
30. Surface Functionalization of PEO Nanofibers Using a TiO2 Suspension as Sheath Fluid in a Modified Coaxial Electrospinning Process
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Jiaxin Jiang, Gaofeng Zheng, Juan Liu, Guoyi Kang, Hao Peng, Jianyi Zheng, and Yifang Liu
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Materials science ,Composite number ,Nanoparticle ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Electrospinning ,0104 chemical sciences ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,Nanofiber ,Titanium dioxide ,Nano ,Surface modification ,Coaxial ,0210 nano-technology - Abstract
Convenient and integration fabrication process is a key issue for the application of functional nanofibers. A surface functionalization method was developed based on coaxial electrospinning to produce ultraviolet(UV) protection nanofibers. The titanium dioxide(TiO2) nanoparticles suspension was delivered through the shell channel of the coaxial spinneret, by which the aggregation of TiO2 nanoparticles was overcome and the distribution uniformity on the surface of polyethylene oxide(PEO) nanofiber was obtained. With the content of TiO2 increasing from 0 to 3%(mass fraction), the average diameter of nanofibers increased from (380± 30) nm to (480±100) nm. The surface functionalization can be realized during the electrospinning process to gain PEO/TiO2 composite nanofibers directly. The uniform distribution of TiO2 nanoparticles on the surface of nanofibers enhanced the UV absorption and resistance performance. The maximum UV protection factor(UPF) value of composite nanofibers reaches 2751. This work presented a novel surface-functionalized way for the preparation of composite nanofiber, which has great application potential in the field of micro/nano system integration fabrication.
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- 2021
31. pH-Responsive Pluronic F127–Lenvatinib-Encapsulated Halogenated Boron-Dipyrromethene Nanoparticles for Combined Photodynamic Therapy and Chemotherapy of Liver Cancer
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Ruihua Shi, Hao Peng, Xuanlong Du, Jingjing Zong, Yewei Zhang, Xin Qing, Zhe Fan, and Wenjing Xu
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chemistry.chemical_classification ,Reactive oxygen species ,Chemotherapy ,Combination therapy ,Chemistry ,General Chemical Engineering ,medicine.medical_treatment ,Photodynamic therapy ,General Chemistry ,Poloxamer ,medicine.disease ,Article ,chemistry.chemical_compound ,medicine ,Cancer research ,BODIPY ,Liver cancer ,Lenvatinib ,QD1-999 - Abstract
Combination therapy such as photodynamic therapy (PDT)-enhanced chemotherapy is regarded as a promising strategy for cancer treatment. Boron-dipyrromethene (BODIPY), as close relatives of porphyrins, was widely used in PDT. However, poor water solubility, rapid metabolism by the body and lack of targeting limits its clinical application. Lenvatinib, as the first-line drug for molecular-targeted therapy of liver cancer, restricted its clinical application for its side effects. Herein, to achieve the synergy between PDT and chemotherapy, we synthesized two halogenated BODIPY, BDPBr2 and BDPCl2, which were prepared into self-assembly nanoparticles with lenvatinib, and were encapsulated with Pluronic F127 through the nanoprecipitation method, namely, LBPNPs (LBBr2 NPs and LBCl2 NPs). The fluorescence quantum yields of LBPNPs were 0.73 and 0.71, respectively. The calculated loading rates of lenvatinib for LBBr2 NPs and LBCl2 NPs were 11.8 and 10.2%, respectively. LBPNPs can be hydrolyzed under weakly acidic conditions (pH 5.0) to generate reactive oxygen species (ROS), and the release rate of lenvatinib reached 88.5 and 82.4%. Additionally, LBPNPs can be effectively taken up by Hep3B and Huh7 liver cancer cells, releasing halogenated BODIPY and lenvatinib in the acidic environment of tumor cells to enhance the targeting performance of chemotherapeutics. Compared with free lenvatinib and separate halogenated BODIPY, LBPNPs can inhibit tumor growth more effectively through pH-responsive chemo/photodynamic synergistic therapy and significantly promote the cascade of caspase apoptotic protease. This study shows that LBPNPs can be a promising nanotheranostic agent for synergetic chemo/photodynamic liver cancer therapy.
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- 2021
32. Counterion Binding Dynamics of a Polyelectrolyte
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Jiang Zhao, Yu Shi, Hao Peng, and Jingfa Yang
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inorganic chemicals ,chemistry.chemical_classification ,Aqueous solution ,Polymers and Plastics ,Chemistry ,Organic Chemistry ,Dynamics (mechanics) ,Counterion binding ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Polyelectrolyte ,0104 chemical sciences ,Inorganic Chemistry ,Molecular level ,Adsorption ,Chemical physics ,Desorption ,Materials Chemistry ,Counterion ,0210 nano-technology - Abstract
The dynamics of adsorption and desorption of counterions on a polyelectrolyte chain in aqueous solution is studied at a single molecular level. The investigation is through the process of fluoresce...
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- 2021
33. Electrochemical oscillation of vanadium ions in anolyte
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Hao Peng, Zuohua Liu, and Changyuan Tao
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vanadyl sulfate ,electrochemical oscillation ,vanadium ,redox flow battery ,Chemistry ,QD1-999 - Abstract
Periodic electrochemical oscillation of the anolyte was reported for the first time in a simulated charging process of the vanadium redox flow batteries. The electrochemical oscillation could be explained in terms of the competition between the growth and the chemical dissolution of V2O5 film. Also, the oscillation phenomenon was possible to regular extra power consumption. The results of this paper might enable new methods to improve the charge efficiency and energy saving for vanadium redox flow batteries.
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- 2017
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34. Asymptomatic Hyperuricemia and Metabolically Unhealthy Obesity: A Cross-Sectional Analysis in the Tianning Cohort
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Hao Peng, Liyun Ren, Jinhua Zhu, Hongfei Shi, Jia Yu, Xintong Wei, Bin Shen, Mingzhi Zhang, Rongyan Zhang, Yan He, and Hongyan Sun
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obesity ,serum uric acid ,medicine.medical_specialty ,Cross-sectional study ,030209 endocrinology & metabolism ,hyperuricemia ,030204 cardiovascular system & hematology ,Gastroenterology ,Asymptomatic ,metabolic syndrome ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Internal medicine ,Metabolically healthy obesity ,Internal Medicine ,medicine ,Hyperuricemia ,Targets and Therapy [Diabetes, Metabolic Syndrome and Obesity] ,Original Research ,Pharmacology ,business.industry ,nutritional and metabolic diseases ,medicine.disease ,Obesity ,chemistry ,Cohort ,Uric acid ,Metabolic syndrome ,medicine.symptom ,business - Abstract
Jia Yu,1,* Hongyan Sun,2,* Jinhua Zhu,3,* Xintong Wei,1 Hongfei Shi,2 Bin Shen,3 Liyun Ren,1 Yan He,1 Rongyan Zhang,3 Mingzhi Zhang,1 Hao Peng1,4 1Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, People’s Republic of China; 2Center for Disease Prevention and Control of Tianning District, Changzhou, People’s Republic of China; 3Center for Disease Prevention and Control of Wujiang District, Suzhou, People’s Republic of China; 4Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Soochow University, Suzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hao PengDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, 199 Renai Road, Industrial Park, Suzhou, 215123, People’s Republic of ChinaTel +86 512 6588 0078Fax +86 512 6588 0052Email penghao@suda.edu.cnObjective: The relationship between obesity and hyperuricemia has been demonstrated by many studies. However, whether or to what extent metabolic condition influents the association between obesity and hyperuricemia was not clear. Here, we aimed to examine the association between obese-metabolic phenotype and hyperuricemia in a large sample of Chinese adults.Methods: According to BMI and metabolic syndrome, obese-metabolic phenotype was defined as metabolically unhealthy obesity (MUO), metabolically healthy obesity (MHO), metabolically unhealthy non-obesity (MUNO) and metabolically healthy non-obesity (MHNO)in the Tianning cohort (N=5072). We conducted a cross-sectional analysis between obese-metabolic phenotype and hyperuricemia, followed by a Mendelian Randomization analysis using GWAS summary data to confirm the causality between uric acid and BMI.Results: The average level of serum UA showed 41.87-higher μmol/L in participants with MHO (β=41.87, P< 0.001) and 63.18-higher μmol/L in participants with MUO (β=63.18, P< 0.001), compared to those with MHNO. Compared to participants with MHNO, those with MUO had the highest likelihood to have hyperuricemia (OR=4.56, P< 0.001), followed by those with MHO (OR=3.32, P< 0.001). Mendelian randomization analysis indicated that uric acid was more likely to be a consequence of BMI (β=0.059, P=6.54× 10− 154).Conclusion: MUO, in comparison with MHO, was significantly associated with hyperuricemia in Chinese adults.Keywords: metabolic syndrome, obesity, serum uric acid, hyperuricemia
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- 2021
35. Metal Reaction-Induced Bulk-Doping Effect in Forming Conductive Source-Drain Regions of Self-Aligned Top-Gate Amorphous InGaZnO Thin-Film Transistors
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Huan Yang, Haishi Fu, Yuxin Min, Baozhu Chang, Xiaoliang Zhou, Hao Peng, Lei Lu, and Shengdong Zhang
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010302 applied physics ,Materials science ,business.industry ,Doping ,chemistry.chemical_element ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Amorphous solid ,Threshold voltage ,Hysteresis ,chemistry ,Aluminium ,Thin-film transistor ,0103 physical sciences ,Optoelectronics ,General Materials Science ,0210 nano-technology ,business ,Saturation (magnetic) ,Sheet resistance - Abstract
In this paper, the aluminum (Al) treatment-induced doping effect on the formation of conductive source-drain (SD) regions of self-aligned top-gate (SATG) amorphous indium gallium zinc oxide (a-InGaZnO or a-IGZO) thin-film transistors (TFTs) is systematically investigated. Average carrier concentration over 1 × 1020 cm-3 and sheet resistance of around 500 Ω/sq result from the Al reaction doping. It is shown that the doping effect is of bulk despite the treatment at the surface. The doping process is disclosed to be a chemical oxidation-reduction reaction, that generates defects of oxygen vacancies and metal interstitials at the metal/a-IGZO interface. Both the generated oxygen vacancies and metal interstitials act as shallow donors, and the oxygen vacancies diffuse rapidly, leading to the bulk-doping effect. The fabricated SATG a-IGZO TFTs with the Al reaction-doped SD regions exhibit both high performance and excellent stability, featuring a low width-normalized SD resistance of about 10 Ω cm, a decent saturation mobility of 13 cm2/(V s), an off current below 1 × 10-13 A, a threshold voltage of 0.5 V, a slight hysteresis of -0.02 V, and a less than 0.1 V threshold voltage shift under 30 V gate bias stresses for 2000 s.
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- 2021
36. Development and Validation of an RNA Sequencing Assay for Gene Fusion Detection in Formalin-Fixed, Paraffin-Embedded Tumors
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Chen Caifu, Hua Dong, Hao Peng, Meng Li, Jianbing Wu, Bin Li, Hao Chen, Lei Tian, Dadong Zhang, Youbing Guo, Rong Huang, Kui Wang, Qing Xu, Li Fugen, and Cuiyun Wang
- Subjects
0301 basic medicine ,Tissue Fixation ,Serial dilution ,Sequence analysis ,Biology ,Pathology and Forensic Medicine ,Fusion gene ,03 medical and health sciences ,chemistry.chemical_compound ,symbols.namesake ,0302 clinical medicine ,Formaldehyde ,Neoplasms ,Humans ,Gene ,Sanger sequencing ,Paraffin Embedding ,Base Sequence ,Sequence Analysis, RNA ,Reproducibility of Results ,RNA ,Molecular biology ,030104 developmental biology ,chemistry ,Cell culture ,030220 oncology & carcinogenesis ,symbols ,Molecular Medicine ,Gene Fusion ,DNA - Abstract
RNA sequencing (RNA-seq) is a well-validated tool for detecting gene fusions in fresh-frozen tumors; however, RNA-seq is much more challenging to use with formalin-fixed, paraffin-embedded (FFPE) tumor samples. We evaluated the performance of RNA-seq to detect gene fusions in clinical FFPE tumor samples. Our assay identified all 15 spiked-in NTRK fusions from RNA reference material and six known fusions from five cancer cell lines. Limit of detection for the assay was assessed with a series of dilutions of RNA from the cell line H2228. These fusions can be detected when the dilution is down to 10%. Good intra-assay and interassay reproducibility was observed in three specimens. For clinical validation, the assay detected 10 of 12 fusions initially identified by a DNA panel (covering 23 gene fusions) in clinical specimens (83.3% sensitivity), whereas one fusion (MET fusion) was identified in another 34 fusion-negative tumor specimens as determined by the DNA panel (negative prediction value of 94.3%). This MET fusion was confirmed by RT-PCR and Sanger sequencing, which found that this is a false-negative result for the DNA panel. The assay also identified 26 extra fusions not covered by the DNA panel, 20 (76.9%) of which were validated by RT-PCR and Sanger sequencing. Therefore, this RNA assay has reasonable performance and could complement DNA-based next-generation sequencing assays.
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- 2021
37. SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model
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Yang Liu, Jian Lei, Jingxin Qiao, Xin Yang, Wen-Pei Li, Shengyong Yang, Yangli Zhou, Xinlei Liu, Yuquan Wei, Yong-Tang Zheng, Xincheng Ni, Chong Huang, Yiguo Hu, Lin-Li Li, Jing-Ming Liu, Yifei Wang, Y. Li, Pei Chen, Ling Xu, Rong-Hua Luo, Wei Yang, Guifeng Lin, Weining Sun, Jun Zou, Hai-Lin Zhang, Baoxue Quan, Jie Zhang, Rui Yao, Kai Wang, Qu Wang, Chenjian Shen, Ming-Hua Li, Qing-Cui Zou, Xiaolong Liu, Yang-Hao-Peng Long, Rui-Cheng Yang, Jing You, Feng-Liang Liu, Guangwen Lu, Xin Mao, Weimin Li, Rui Zeng, and Zilei Duan
- Subjects
Letter ,medicine.medical_treatment ,viruses ,Virus Replication ,Telaprevir ,Rats, Sprague-Dawley ,chemistry.chemical_compound ,Mice ,0302 clinical medicine ,Lung ,Coronavirus 3C Proteases ,0303 health sciences ,Multidisciplinary ,Microbio ,Viral Load ,Drug screening ,030220 oncology & carcinogenesis ,ddc:500 ,Structural biology ,Viral load ,Oligopeptides ,medicine.drug ,Genetically modified mouse ,Antagonists & inhibitors ,Proline ,Cell Survival ,Mice, Transgenic ,Antiviral Agents ,Cell Line ,03 medical and health sciences ,Boceprevir ,Report ,Virology ,medicine ,Animals ,Humans ,Protease Inhibitors ,030304 developmental biology ,Protease ,business.industry ,SARS-CoV-2 ,COVID-19 ,Interferon-beta ,In vitro ,Rats ,COVID-19 Drug Treatment ,Chemokine CXCL10 ,Disease Models, Animal ,chemistry ,Viral replication ,Drug Design ,business ,Reports - Abstract
Targeting the SARS-CoV-2 main protease Vaccines are an important tool in the fight against COVID-19, but developing antiviral drugs is also a high priority, especially with the rise of variants that may partially evade vaccines. The viral protein main protease is required for cleaving precursor polyproteins into functional viral proteins. This essential function makes it a key drug target. Qiao et al. designed 32 inhibitors based on either boceprevir or telaprevir, both of which are protease inhibitors approved to treat hepatitis C virus. Six compounds protected cells from viral infection with high potency, and two of these were selected for in vivo studies based on pharmokinetic experiments. Both showed strong antiviral activity in a mouse model. Science, this issue p. 1374, Designed SARS-CoV-2 Mpro (main protease) inhibitors display excellent antiviral activity both in vitro and in a transgenic mouse model., The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continually poses serious threats to global public health. The main protease (Mpro) of SARS-CoV-2 plays a central role in viral replication. We designed and synthesized 32 new bicycloproline-containing Mpro inhibitors derived from either boceprevir or telaprevir, both of which are approved antivirals. All compounds inhibited SARS-CoV-2 Mpro activity in vitro, with 50% inhibitory concentration values ranging from 7.6 to 748.5 nM. The cocrystal structure of Mpro in complex with MI-23, one of the most potent compounds, revealed its interaction mode. Two compounds (MI-09 and MI-30) showed excellent antiviral activity in cell-based assays. In a transgenic mouse model of SARS-CoV-2 infection, oral or intraperitoneal treatment with MI-09 or MI-30 significantly reduced lung viral loads and lung lesions. Both also displayed good pharmacokinetic properties and safety in rats.
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- 2021
38. Influence of Particle Size on the Heat and Mass Transfer Characteristics of Methane Hydrate Formation and Decomposition in Porous Media
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Xiao-Yan Li, Xiao-Sen Li, Gang Li, Hao-Peng Zeng, Heng-Qi Hu, Yu Zhang, Yi Wang, and Kun Wan
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Materials science ,General Chemical Engineering ,Clathrate hydrate ,Energy Engineering and Power Technology ,Permafrost ,Deep sea ,Decomposition ,Methane ,chemistry.chemical_compound ,Fuel Technology ,Chemical engineering ,chemistry ,Mass transfer ,Particle size ,Porous medium - Abstract
In nature, permafrost regions and deep ocean sediments contain a large amount of gas hydrate. As a basic property of the sediments, the particle size of the porous media is a critical factor affect...
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- 2021
39. Eriodictyol attenuates dextran sodium sulphate-induced colitis in mice by regulating the sonic hedgehog signalling pathway
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Ru Wang, Lei Shen, Hao Peng, and Huimin Li
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Male ,Cyclopamine ,Colon ,Pharmaceutical Science ,Context (language use) ,RM1-950 ,Pharmacology ,Occludin ,Mice ,chemistry.chemical_compound ,Drug Discovery ,medicine ,Animals ,oxidative stress ,Hedgehog Proteins ,Colitis ,Dextran Sulfate ,Veratrum Alkaloids ,ibd ,General Medicine ,epithelial barrier destruction ,Eriodictyol ,medicine.disease ,Hedgehog signaling pathway ,Mice, Inbred C57BL ,Complementary and alternative medicine ,chemistry ,Apoptosis ,inflammation ,Flavanones ,Models, Animal ,Cytokines ,Molecular Medicine ,Colitis, Ulcerative ,Therapeutics. Pharmacology ,Smoothened ,Research Article ,Signal Transduction - Abstract
Context Eriodictyol (EDT) is a flavonoid with strong anti-inflammatory, anti-apoptotic, and antioxidant properties. Objective To investigate the protective effect and mechanism of EDT in ulcerative colitis (UC). Materials and methods UC model was induced by 3% dextran sulphate sodium (DSS) solution for 7 days, meanwhile, EDT and Smoothened (Smo) inhibitor cyclopamine (Cyc) were intraperitoneally injected. In the first experiment, C57BL/6 mice divided into blank control, DSS, DSS + EDT (20 or 40 mg/kg) groups. In second experiment, added Cyc (5 mg/kg) and EDT + Cyc groups. All mice were sacrificed on day 8. Disease activity index (DAI), colon length and colon histology as well as MDA levels, SOD, and GSH-Px activities were measured. The expression of Sonic hedgehog (Shh), Patched, Smo, glioblastoma-1, zonula occludens-1 (ZO-1), occludin, cleaved caspase 3, Bax and Bcl-2 in colon was detected using RT-PCR and Western blotting. Results After EDT treatment, compared with the DSS group, DAI (2.33 ± 0.516 vs. 3.67 ± 0.516), colon shortening (5.27 ± 0.476 vs. 4.53 ± 0.528 cm) and histological score (6.67 ± 1.211 vs. 12 ± 1.265) was significantly decreased. EDT also reduced inflammation, oxidative stress and apoptosis in colon. Additionally, EDT increased the expression of the tight junction proteins ZO-1 (35%) and occludin (66.3%). Mechanistically, EDT upregulated the Shh signalling pathway. However, Cyc-mediated inhibition of the Shh pathway partially abolished the effects of EDT. Discussion and Conclusions These results indicate EDT attenuates DSS-induced colitis by activating the Shh pathway. Further clinical trials are needed to demonstrate its efficacy on UC.
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- 2021
40. Inhibition effect of ZrF4 on UO2 precipitation in the LiF–BeF2 molten salt
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Nan Ji, Hao Peng, Yu-Long Song, Yu Gong, Leidong Xie, and Wei Huang
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Precipitation (chemistry) ,General Chemical Engineering ,FLiBe ,02 engineering and technology ,General Chemistry ,Solubility equilibrium ,Uranium tetrafluoride ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,chemistry.chemical_compound ,chemistry ,Solubility ,Zirconium tetrafluoride ,Molten salt ,0210 nano-technology ,Dissolution ,Nuclear chemistry - Abstract
The dissolution–precipitation behavior of zirconium dioxide (ZrO2) in molten lithium fluoride–beryllium fluoride (LiF–BeF2, (2 : 1 mol, FLiBe)) eutectic salt at 873 K was studied. The results of the dissolution experiment showed that the saturated solubility of ZrO2 in the FLiBe melt was 3.84 × 10−3 mol kg−1 with equilibrium time of 6 h, and its corresponding apparent solubility product (K′sp) was 3.40 × 10−5 mol3 kg−3. The interaction between Zr(IV) and O2− was studied by titrating lithium oxide (Li2O) into the FLiBe melt containing zirconium tetrafluoride (ZrF4), and the concentration of residual Zr(IV) in the melt gradually decreased due to precipitate formation. The precipitate corresponded to ZrO2, as confirmed by the stoichiometric ratio and X-ray diffraction analysis. The K′sp was 3.54 × 10−5 mol3 kg−3, which was highly consistent with that from the dissolution experiment. The obtained K′sp of ZrO2 was in the same order of magnitude as that of uranium dioxide (UO2), indicating that a considerable amount of ZrF4 could inhibit the UO2 formation when oxide contamination occurred in the melt containing ZrF4 and uranium tetrafluoride (UF4). Further oxide titration in the LiF–BeF2–ZrF4 (5 mol%)–UF4 (1.2 mol%) system showed that ZrO2 was formed first with O2− addition less than 1 mol kg−1, and the precipitation of UO2 began only after the O2− addition reached 1 mol kg−1 and the precipitation of ZrO2 decreased the ZrF4 concentration to 0.72 mol kg−1 (3 mol%). Lastly, UO2 and ZrO2 coprecipitated with further O2− addition of more than 1 mol kg−1. The preferential formation of ZrO2 effectively avoided the combination of UF4 and O2−. This study provides a solution for the control of UO2 precipitation in molten salt reactors.
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- 2021
41. Optimizing two green-like biomass pretreatments for maximum bioethanol production using banana pseudostem by effectively enhancing cellulose depolymerization and accessibility
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Yanting Wang, Hairong Gao, Hao Peng, Liangcai Peng, Fei Liu, Zhen Hu, Yuqi Li, Yuanyuan Tu, Hailang Wang, Hua Yu, Guifen Zhang, and Jingyang Li
- Subjects
010405 organic chemistry ,Renewable Energy, Sustainability and the Environment ,Depolymerization ,020209 energy ,food and beverages ,Energy Engineering and Power Technology ,Biomass ,02 engineering and technology ,01 natural sciences ,0104 chemical sciences ,Hydrolysis ,chemistry.chemical_compound ,Fuel Technology ,chemistry ,Biofuel ,0202 electrical engineering, electronic engineering, information engineering ,Green liquor ,Lignin ,Hemicellulose ,Food science ,Cellulose - Abstract
The banana is an important fruit crop that generates enormous quantities of lignocellulose-rich pseudostem residues that can be converted into biofuels and biochemicals. By performing response surface methodological modeling, optimized green liquor (GL) and liquid hot water (LHW) pretreatments of representative banana samples were studied. Using banana (BP-1) pseudostem residues rich in directly fermentable soluble sugars (27% hexoses and 2.7% pentoses via dry matter) and easily digestible xyloglucans, we measured nearly complete enzymatic saccharification with a hexose yield of 99% (% cellulose) from the most optimal GL pretreatment under relatively mild conditions. Notably, both optimal LHW (20 min, 110 °C) and GL (26.74% TTA, 105 °C, 26 min) pretreatments led to the highest bioethanol yields achieved thus far, at 27% and 31% (% dry matter), respectively, subjective to yeast fermentation with all hexose sources obtained in the BP-1 sample. Furthermore, we determined that optimal LHW and GL pretreatments extracted lignin by 25% and 40%, and reduced the cellulose crystalline index by 35% and 44% and polymerization degree by 34% and 36%, respectively, with distinctively altered lignin and hemicellulose features. Cellulose accessibility was increased 2–3 fold for remarkably enhanced enzymatic saccharification of biomass. Hence, we propose a mechanism model to elucidate why banana lignocellulose underwent complete biomass enzymatic saccharification under mild green-like pretreatments, providing an applicable strategy that can be used to produce large quantities of bioethanol from banana lignocellulose residues and beyond.
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- 2021
42. Box-copper catalyzed cascade asymmetric amidation for chiral exo-methylene aminoindoline derivatives
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Xing-Wang Wang, Hao-Di Yang, Xiao-Peng Yang, Hao-Peng Lv, and Bai-Lin Wang
- Subjects
Annulation ,Ligand ,Chemistry ,Organic Chemistry ,Enantioselective synthesis ,Biochemistry ,Combinatorial chemistry ,chemistry.chemical_compound ,Nucleophile ,Cascade ,Intramolecular force ,Copper catalyzed ,Physical and Theoretical Chemistry ,Methylene - Abstract
Enantioselective copper-catalyzed cascade inter- and intramolecular amidation was achieved between ethynyl benzoxazinanones and α-halohydroxamates in the presence of an indapybox ligand. The one-pot cascade transformation was triggered by the attack of hydroxamates to dipolar copper–allenylidene intermediates, followed by a nucleophilic annulation reaction. Thus, a series of exo-methylene 3-aminoindoline derivatives were obtained in good yields with high enantioselectivities under mild reaction conditions.
- Published
- 2021
43. Effect of Surfactant on Water Content of Phosphogypsum
- Author
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Bing Li, Hao Peng, and Jing Guo
- Subjects
crystallization ,filtration rate ,phosphogypsum ,surfactant ,water content ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Phosphogypsum is a kind of solid waste produced in wet process of producing phosphoric acid, which affects the filtration rate and water content of phosphogypsum. The effects of single surfactant sodium dodecyl sulfate (SDS), sodium dodecylbenzene sulfonate (SDBS), stearic acid (SR) and polydimethylsiloxane (PDMS) and coupled surfactants on the water content of phosphogypsum were investigated. The results show that, during the leaching process, surfactant strengthened the interfacial interactions between molecules through hydrophobic and hydrophilic orientation on solid–liquid interface, reduced the surface tension and contact angle to improve the filtration rate and reduced the soluble phosphorus loss, thereby improving the leaching rate of phosphate rock and reducing the water content of phosphogypsum. Among them, the water content of phosphogypsum was better controlled by stearic acid and sodium dodecylbenzene sulfonate than the other surface surfactants. Compared with the blank group, the stearic acid and sodium dodecylbenzene sulfonate increased the filtration rate of phosphogypsum by 24.34%, the moisture content decreased by 3%, and the phosphate leaching rate increased by 4.36%.
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- 2019
- Full Text
- View/download PDF
44. Electrochemical Removal of Chromium (VI) from Wastewater
- Author
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Hao Peng, Yumeng Leng, and Jing Guo
- Subjects
electrochemical ,chromium ,kinetic ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The removal of hexavalent chromium has attracted much attention as it is a hazardous contaminant. Electrochemical reduction technology was applied to remove chromium (VI) from wastewater. The mechanisms and parameters that affect the reduction process were investigated. The results showed that the reduction efficiency was significantly affected by the concentration of H2SO4, current density, and reaction temperature. The reduction efficiency was up to 86.45% at an H2SO4 concentration of 100 g/L, reaction temperature of 70 °C, current density at 50 A/m2, reaction time at 180 min, and stirring rate of 500 rpm. The reduction process of chromium (VI) followed a pseudo-first-order equation, and the reduction rate constant could be expressed as Kobs = k [H2SO4]1·[j]4·exp−4170/RT.
- Published
- 2019
- Full Text
- View/download PDF
45. Highly efficient oxidative-alkaline-leaching process of vanadium-chromium reducing residue and parameters optimization by response surface methodology
- Author
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Ya Chen, Hao Peng, Qian Shang, Jing Guo, Ronghua Chen, and Liuying Zhang
- Subjects
Chromium ,inorganic chemicals ,Municipal solid waste ,0208 environmental biotechnology ,Inorganic chemistry ,Vanadium ,chemistry.chemical_element ,02 engineering and technology ,Oxidative phosphorylation ,010501 environmental sciences ,Solid Waste ,01 natural sciences ,Residue (chemistry) ,otorhinolaryngologic diseases ,Sodium Hydroxide ,Environmental Chemistry ,Response surface methodology ,Waste Management and Disposal ,0105 earth and related environmental sciences ,Water Science and Technology ,Chemistry ,technology, industry, and agriculture ,General Medicine ,020801 environmental engineering ,Oxidative Stress ,Leaching (metallurgy) - Abstract
Vanadium-chromium reducing residue was not only a typical solid waste in the steel industry but also a valuable secondary source for recovery of vanadium and chromium. A highly efficient oxidative-alkaline-leaching technology with Na
- Published
- 2020
46. Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development
- Author
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Zhen Qin, Ye Liu, Yong Liu, Dan Su, Dexu Xu, Yuan Zhao, Hao Peng, Lusong Luo, Bo Ren, Fan Wang, Changxin Huo, Min Wei, Yingcai Feng, Huibin Yan, Qiu Ming, Yin Guo, Kuang Xianzhao, Wenfeng Gong, Zhiwei Wang, Hong Xu, Xuebing Sun, Yajuan Gao, Xuesong Liu, Ruipeng Qi, Lai Wang, Beibei Jiang, Changyou Zhou, Yiyuan Wu, Fenglong Yu, Yutong Zhu, Hexiang Wang, Lei Lv, Xing Wang, and Tristin Tang
- Subjects
Indoles ,DNA repair ,Poly ADP ribose polymerase ,Carbazoles ,Poly(ADP-ribose) Polymerase Inhibitors ,01 natural sciences ,Mice ,Structure-Activity Relationship ,03 medical and health sciences ,Dogs ,Microsomes ,Neoplasms ,Drug Discovery ,Animals ,Humans ,Structure–activity relationship ,IC50 ,Polymerase ,Cell Proliferation ,030304 developmental biology ,chemistry.chemical_classification ,Fluorenes ,0303 health sciences ,Binding Sites ,biology ,Xenograft Model Antitumor Assays ,Rats ,0104 chemical sciences ,Isoenzymes ,Molecular Docking Simulation ,010404 medicinal & biomolecular chemistry ,Enzyme ,chemistry ,PARP inhibitor ,biology.protein ,Cancer research ,Molecular Medicine ,Female ,Poly(ADP-ribose) Polymerases ,Drug metabolism ,Half-Life - Abstract
Poly (ADP-ribose) polymerase (PARP) plays a significant role in DNA repair responses; therefore, this enzyme is targeted by PARP inhibitors in cancer therapy. Here we have developed a number of fused tetra- or pentacyclic dihydrodiazepinoindolone derivatives with excellent PARP enzymatic and cellular PARylation inhibition activities. These efforts led to the identification of pamiparib (BGB-290, 139), which displays excellent PARP-1 and PARP-2 inhibition with IC50 of 1.3 and 0.9 nM, respectively. In a cellular PARylation assay, this compound inhibits PARP activity with IC50 = 0.2 nM. Cocrystal of pamiparib shows similar binding sites with PARP with other PARP inhibitors, but pamiparib is not a P-gp substrate and shows excellent drug metabolism and pharmacokinetics (DMPK) properties with significant brain penetration (17-19%, mice). The compound is currently being investigated in phase III clinical trials as a maintenance therapy in platinum-sensitive ovarian cancer and gastric cancer.
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- 2020
47. Glucocorticoids induce femoral head necrosis in rats through the ROS/JNK/c‐Jun pathway
- Author
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Hao Peng, Zhigang Nie, Puji Peng, and Fei Sun
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musculoskeletal diseases ,Male ,0301 basic medicine ,autophagy ,medicine.medical_specialty ,MAP Kinase Signaling System ,Proto-Oncogene Proteins c-jun ,JNK/c‐Jun signaling pathway ,Avascular necrosis ,Dexamethasone ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,Femoral head ,0302 clinical medicine ,Femur Head Necrosis ,Internal medicine ,medicine ,Animals ,Humans ,Glucocorticoids ,Research Articles ,chemistry.chemical_classification ,Reactive oxygen species ,Osteoblasts ,biology ,Cytochrome c ,Autophagy ,apoptosis ,Femur Head ,ROS ,Osteoblast ,medicine.disease ,Rats ,Disease Models, Animal ,030104 developmental biology ,Endocrinology ,medicine.anatomical_structure ,chemistry ,Apoptosis ,030220 oncology & carcinogenesis ,biology.protein ,hormonal osteonecrosis of the femoral head ,Signal transduction ,Reactive Oxygen Species ,Research Article - Abstract
Apoptosis of osteoblasts caused by glucocorticoid (GC) is the biological basis of steroid‐induced avascular necrosis of the femoral head (SANFH). We found that GC can induce osteoblast apoptosis and autophagy through the ROS/JNK/c‐Jun signaling pathway, which contributes to SANFH. Therefore, the autophagy inhibitor 3‐MA might have potential for development into a treatment for SANFH., Osteonecrosis of the femoral head (ONFH) is a common clinical disease with a high disability rate. Apoptosis of osteoblasts caused by high‐dose short‐term or low‐dose long‐term glucocorticoid (GC) administration is the biological basis of steroid‐induced avascular necrosis of the femoral head (SANFH). The pathogenesis of SANFH has not yet been fully elucidated, and there is currently a lack of effective clinical treatments. Here, we investigated the role of the reactive oxygen species (ROS)/JNK/c‐Jun signaling pathway in SANFH. Dexamethasone (Dex) was used to induce apoptosis in osteoblasts, and this resulted in a significant increase in levels of p‐JNK, p‐c‐Jun, Bax, caspase‐3, caspase‐9, cytochrome C, Beclin‐1, and LC3, and a decrease in levels of P62 and Bcl‐2. In addition, intracellular ROS levels were increased and mitochondrial membrane potential was decreased. Administration of 3‐MA, an autophagy inhibitor, attenuated Dex‐mediated changes in autophagy and apoptosis. A rat model of ONFH exhibited severe bone trabecular hollow bone pits along with a significant increase in femoral head cell apoptosis compared with the control group. Additionally, micro‐CT analysis showed that both bone tissue content and femoral head integrity were significantly reduced in the ONFH group. Furthermore, 3‐MA treatment decreased the effect of Dex on GC‐induced ONFH and osteoblast apoptosis in rats and could counteract microstructure destruction due to femoral head necrosis. In summary, our data suggest that GC can induce osteoblast apoptosis and autophagy through the ROS/JNK/c‐Jun signaling pathway, which contributes to ONFH.
- Published
- 2020
48. Study on the environmental effects of heavy metals in coal gangue and coal combustion by ReCiPe2016 for life cycle impact assessment
- Author
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Hao Peng, Feng-ling Yang, Cheng Fangqin, and Wang Baofeng
- Subjects
Flue gas ,Pulverized coal-fired boiler ,Waste management ,010405 organic chemistry ,Chemistry ,business.industry ,Boiler (power generation) ,Coal combustion products ,02 engineering and technology ,Combustion ,01 natural sciences ,0104 chemical sciences ,020401 chemical engineering ,Fly ash ,Coal ,Fluidized bed combustion ,0204 chemical engineering ,business - Abstract
During coal and coal gangue combustion, many heavy metal pollutants are emitted and cause serious environmental problems. In this paper, the environmental effect values of As and Pb emission during coal gangue and coal combustion in the 330 MW pulverized coal boiler, 50 kW circulated fluidized bed boiler and laboratory were calculated by ReCiPe2016. The results show that when coal combustion in 330 MW pulverized coal boiler, the environment effect values of as for bottom slag, fly ash and flue gas are 3.28×10−6, 2.68×10−5 and 3.89×10−3 respectively; while the environment effect value of Pb for bottom slag, fly ash and flue gas are 8.57×10−6, 6.00×10−5 and 4.83×10−2, respectively. The environmental effects of As and Pb in bottom slag are lower than those in the fly ash; and the environmental effects of As and Pb on air are higher than those on soil. Moreover, when coal combustion in the 50 kW circulated fluidized boiler, the effect values of As and Pb in fly ash on environment are 3.26×10−5 and 1.28×10−4; and the effect values of As and Pb in bottom slag are 1.16×10−6 and 1.43×10−5 respectively. The results also show that when coal gangue combustion in the laboratory, the effect values of As and Pb emission increase with increasing of the temperature; and the proportions of total environmental effects of As and Pb on air are higher than those on soil. Besides that, this study also indicates that the effect of Pb emitted into environment is higher than that of As at the same conditions during coal combustion both in circulated fluidized boiler and pulverized coal boiler. The results may provide basic data for predicting the environmental effects of As and Pb during coal gangue combustion in circulating fluidized bed for life cycle impact assessment.
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- 2020
49. Recovery of chromium by calcium-roasting, sodium-roasting, acidic leaching, alkaline leaching and sub-molten technology: a review
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Jing Guo, Huisheng Huang, Liping Lv, Bing Li, and Hao Peng
- Subjects
inorganic chemicals ,Chemistry ,Sodium ,technology, industry, and agriculture ,food and beverages ,chemistry.chemical_element ,02 engineering and technology ,010501 environmental sciences ,Calcium ,Contamination ,equipment and supplies ,021001 nanoscience & nanotechnology ,Pulp and paper industry ,complex mixtures ,01 natural sciences ,Chromium ,Environmental Chemistry ,Leaching (metallurgy) ,0210 nano-technology ,0105 earth and related environmental sciences ,Roasting - Abstract
Chromium is a major strategic mineral widely used in industrial processes, yet mineral resources are decreasing, calling for advanced recycling techniques to recover chromium from ores, waste and contaminated media. Here, we review chromium resources and methods to leach out Cr, such as calcium-roasting, sodium-roasting, acidic leaching, alkaline leaching and sub-molten technology.
- Published
- 2020
50. Interfacial Structure of Water as a New Descriptor of the Hydrogen Evolution Reaction
- Author
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Zhi-Chao Huang-Fu, Bang-An Lu, Yu-Yang Li, Yan-Xia Jiang, Xi-Ming Qu, Shi-Gang Sun, Jin-Yu Ye, Guang Li, Linfan Shen, Jia Liu, Wen-Bin Cai, Junming Zhang, and Hao Peng
- Subjects
010405 organic chemistry ,Chemistry ,Kinetics ,Nanoparticle ,General Chemistry ,General Medicine ,010402 general chemistry ,Photochemistry ,01 natural sciences ,Catalysis ,Dissociation (chemistry) ,0104 chemical sciences ,symbols.namesake ,Adsorption ,symbols ,Molecule ,Fourier transform infrared spectroscopy ,Raman spectroscopy - Abstract
Driven by the persisting poor understanding of the sluggish kinetics of the hydrogen evolution reaction (HER) on Pt in alkaline media, a direct correlation of the interfacial water structure and activity is still yet to be established. Herein, using Pt and Pt-Ni nanoparticles we first demonstrate a strong dependence of the proton donor structure on the HER activity and pH. The structure of the first layer changes from the proton acceptors to the donors with increasing pH. In the base, the reactivity of the interfacial water varied its structure, and the activation energies of water dissociation increased in the sequence: the dangling O-H bonds < the trihedrally coordinated water < the tetrahedrally coordinated water. Moreover, optimizing the adsorption of H and OH intermediates can re-orientate the interfacial water molecules with their H atoms pointing towards the electrode surface, thereby enhancing the kinetics of HER. Our results clarified the dynamic role of the water structure at the electrode-electrolyte interface during HER and the design of highly efficient HER catalysts.
- Published
- 2020
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