652 results on '"Lijun Zhang"'
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2. Inspirations from Field-Reservoir CO2 Flooding with Different Miscible Degrees under Cross-Scale Oil Reservoir Conditions
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Lijun Zhang, Xianhong Tan, Xiaofeng Tian, Yujia Jiao, Wenbo Zhang, Xiaohan Shu, Borui Li, Xiliang Liu, and Hao Chen
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Chemistry ,QD1-999 - Published
- 2024
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3. Semianalytical Modeling for Multiphase Flow in a Fractured Low-Permeability Gas Condensate Reservoir
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Fuguo Yin, Shiqing Cheng, Xiuwei Liu, Lijun Zhang, Huisheng Liu, Wenpeng Bai, DengKe Shi, and Yang Wang
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Chemistry ,QD1-999 - Published
- 2023
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4. A Survey on Visual Mamba
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Hanwei Zhang, Ying Zhu, Dan Wang, Lijun Zhang, Tianxiang Chen, Ziyang Wang, and Zi Ye
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Mamba ,computer vision ,state space model ,application ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
State space models (SSM) with selection mechanisms and hardware-aware architectures, namely Mamba, have recently shown significant potential in long-sequence modeling. Since the complexity of transformers’ self-attention mechanism is quadratic with image size, as well as increasing computational demands, researchers are currently exploring how to adapt Mamba for computer vision tasks. This paper is the first comprehensive survey that aims to provide an in-depth analysis of Mamba models within the domain of computer vision. It begins by exploring the foundational concepts contributing to Mamba’s success, including the SSM framework, selection mechanisms, and hardware-aware design. Then, we review these vision Mamba models by categorizing them into foundational models and those enhanced with techniques including convolution, recurrence, and attention to improve their sophistication. Furthermore, we investigate the widespread applications of Mamba in vision tasks, which include their use as a backbone in various levels of vision processing. This encompasses general visual tasks, medical visual tasks (e.g., 2D/3D segmentation, classification, image registration, etc.), and remote sensing visual tasks. In particular, we introduce general visual tasks from two levels: high/mid-level vision (e.g., object detection, segmentation, video classification, etc.) and low-level vision (e.g., image super-resolution, image restoration, visual generation, etc.). We hope this endeavor will spark additional interest within the community to address current challenges and further apply Mamba models in computer vision. more...
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- 2024
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5. The Application of Laser-Scanning 3D Model Reconstruction Technology for Visualizing a Decommissioning Model of the Heavy Water Research Reactor
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Wensi Li, Yu Zhang, Ruizhi Li, Lijun Zhang, Xingwang Zhang, Hongyin Li, Peng Nie, and Shengdong Zhang
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decommissioning ,3D laser scanning ,heavy water research reactor ,model reconstruction ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Currently, over 100 nuclear power units globally have been in operation for more than 40 years. Hindered by the limitations of computer technology at the time, these nuclear facilities lack detailed electronic drawings. Activities such as equipment replacement and process circuit system modifications during operation result in discrepancies between paper drawings and actual conditions. Given the complexity and irreversibility of nuclear facility decommissioning activities, virtual simulation technology is often employed before the decommissioning process begins to assist in designing and validating decommissioning plans. Consequently, the creation of high-precision 3D models is crucial for subsequent decommissioning designs. Through innovatively utilizing laser-scanning 3D model reconstruction technology in the reconstruction of the model of China’s first heavy water research reactor undergoing decommissioning, this paper provides an overview of the process of laser-scanning 3D model reconstruction and its application in reconstructing the heavy water research reactor model. Using a 3D laser scanner, four decommissioning areas of the heavy water research reactor, including the reactor building, secondary water pump room, ventilation center, and low-level radioactive wastewater storage tank area, were subjected to 3D laser scanning. The acquired point cloud data from 572 scanning stations were processed using point cloud processing software for denoising, stitching, and triangulation. The triangulated model was then imported into modeling software for 3D reconstruction, ultimately establishing a digitalized model of the heavy water research reactor suitable for subsequent decommissioning simulation and design. more...
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- 2024
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6. Analysis of Adaptability and Application Potential of Supercritical Multi-Source Multi-Component Thermal Fluid Technology for Offshore Heavy Oil in China
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Yan Sun, Lijun Zhang, Yuting Bai, Taichao Wang, Wenbo Zhang, Jipeng Zhang, and Pengcheng Liu
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supercritical multi-source multi-component thermal fluid ,offshore heavy oil reservoir ,numerical simulation method ,adaptability evaluation ,application potential evaluation method ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Supercritical multi-source, multi-component thermal fluid is a heavy oil thermal recovery method independently developed by China National Offshore Oil Co., Ltd (Beijing, China). It uses waste liquid at the production end of the production well as the water source, the injection medium temperature exceeds 374 °C, 22.1 MPa, and all the produced flue gas is re-injected. Compared with steam huff and puff technology, supercritical technology has the advantages of high enthalpy value, high heat utilization rate, good oil displacement effect, and being green and pollution-free. In addition, its oil–water treatment cost is low, it can realize the reuse of organic matter, it has a good cost advantage of water treatment under the background of low carbon, and it is a thermal recovery method with great application potential for offshore heavy oil. Therefore, it is necessary to carry out research on the adaptability and application potential of supercritical multi-source, multi-heat flow thermal recovery technology in the sea. Based on the laboratory one-dimensional displacement experiment, this paper reveals the mechanism of heavy oil supercritical multi-source multi-component thermal fluid displacement and the contribution of supercritical components to the displacement effect, and establishes the supercritical multi-source, multi-component thermal fluid numerical simulation characterization method. Combined with the characteristics of offshore heavy oil reserves, the main control factors affecting supercritical multi-source, multi-component thermal fluid development were established by numerical simulation and orthogonal test methods, and the adaptive screening method of offshore supercritical technology was established. The application potential of 670 million tons of offshore heavy oil reserves was evaluated and sorted, and KL 10-2 oilfield was selected as the pilot test oilfield. The results show that supercritical technology has great advantages in oil displacement and water treatment cost reduction, and the results play an important guiding significance for the development of offshore heavy oil technology system and the iteration of new technology. more...
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- 2024
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7. Air-Stable Near-Infrared Sensitive Organic Phototransistors Realized via Tri-Layer Planar Heterojunction
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Yao Hu, Yongshun Wang, Yao Li, and Lijun Zhang
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lead phthalocyanine ,near infrared ,organic phototransistors ,planar heterojunction ,air stability ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Near-infrared (NIR) light has many applications in agriculture, transportation, medicine, the military, and other fields. Lead phthalocyanine (PbPc) exhibits excellent near-infrared (NIR) light absorption characteristics and is widely used in NIR-sensitive organic photodetectors. In this work, PbPc-based NIR organic phototransistors (OPTs) with different active layer structures were designed and fabricated. The photo-absorption characteristics of organic films, photosensitive properties, and air stability of the devices were investigated. The results suggested that (i) the bilayer planar heterojunction (PHJ) devices exhibit far better photosensitive performance than the single layer ones due to higher mobility of the formers than the latters; (ii) the bilayer PHJ ones with p-type channel have equivalent photosensitive performance to those with n-type channel owing to equivalent mobility, higher NIR absorption and lower exciton dissociation efficiency of the formers than the latters; (iii) the bilayer PHJ ones with p-type channel possess superior air stability to those with n-type channel thanks to better air stability of pentacene channel layer than C60 channel layer; (iv) the tri-layer PHJ ones perform better than the bilayer PHJ ones with p-type channel and exhibit a high photoresponsivity of 1415 mA/W and a maximum photo-to-dark current ratio of 1.2 × 104, and such an outstanding performance benefits from the virtues of tri-layer PHJ structure including high light absorption, carrier mobility and exciton dissociation efficiency; and (v) the air stability of the tri-layer PHJ ones is better than that of the bilayer PHJ ones with p-type channel, which can be attributed to the passivation of the top-level C60 layer. more...
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- 2023
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8. Influence of Interference Fit and Temperature on High-Speed Permanent Magnet Motor
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Yiming Zeng, Shanju Yang, Xinyi Yang, Qi Wang, Lijun Zhang, Jie Hao, and Wencan Hua
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rotor strength ,chamfer ,finite element analysis ,interference fit ,stress ,failure temperature ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
A high-speed permanent magnet motor is the core driving component of a centrifugal air compressor. The power of the centrifugal air compressor is output by the motor. Its safety and reliability are embodied in the stability of the rotor structure, which greatly affects the stability and working efficiency of the centrifugal air compressor. Much research has focused on the material strength, structural characteristics, and fit clearance of a high-speed rotor, whereas few research articles have focused on the influence of interference fit of high-speed and ultra-high-speed permanent magnet motors, and there is also little research on the thermal failure caused by temperature in high-speed motors. In this paper, the influence of the interference fit and temperature of the high-speed permanent magnet motor is studied. Using finite element analysis conducted by Ansys to obtain simulation data, the influencing factors of the strength of the interference are analyzed comprehensively in the centrifugal compressor rotor system. The interference value and rotational speed range are determined via numerical calculation. Under the condition of minimum interference, when the calculated speed reaches 137,628.82 rpm, the structure of the rotor is loose and fails, which is a mechanical failure caused by the relative sliding of the magnet and the sheath. The calculated speed value differs from the simulation result by about 1.2%. The simulation results show that the maximum stress of the structure can be reduced from 1186.1 MPa to 308.42 MPa by adding chamfer to the end covers in interference fit structure. The effects of interference value, rotational speed, temperature, and sheath thickness on the structure are also analyzed. From the perspective of temperature on structural reliability, the failure temperature of the structure decreases when the interference value increases. The lowest failure temperature is 182.3 °C when the interference value is 70 μm. After that, the interference value increases and the failure temperature increases. The reason for this is the interaction between radial stress and contact stress. These results are caused by the interaction between interference fit and temperature, which should be paid attention to when the structure of a high-speed permanent magnet motor is designed. more...
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- 2023
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9. Design of Wideband Decoupling Antenna Array for 5G Smartphones at N77/N78/N79/WLAN 5 GHz Bands
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Zhao Liu, Yongshun Wang, Yao Hu, and Lijun Zhang
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antenna array ,characteristic mode (CM) ,DGS ,multiple-input multiple-output (MIMO) ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
We propose a broadband decoupled antenna pair for 5G mobile terminals. The broadband decoupled design of this antenna pair is based on the characteristic mode theory (CMA) and defective ground structure. First, CMA is applied to obtain the characteristic current distribution of the antenna, then the characteristic current sensitive regions are optimized to make the antenna introduce new modes and obtain a wide bandwidth. After that, an antenna pair is added with defective ground structure to obtain a wideband decoupled antenna pair that has small size and high isolation. Next, an eight-element MIMO antenna system is constructed with the obtained broadband decoupled antenna pair, and a composite decoupling technique consisting of defective ground structure (DGS) and decoupling strip is applied to the two antenna pairs on the same side of the bezel to improve the isolation. The simulation and prototype test results show that the eight-element MIMO antenna with −10 dB bandwidth of 3.28~5.85 GHz mainly covers the N77/N78/N79/WLAN 5 GHz band, and the antenna pair are only 1.6 mm apart with good isolation (−16.7 dB), the ECC is less than 0.01, and it has a good total efficiency at the main operating frequency. Finally, the effect of a user’s hand on the antenna is briefly analyzed to verify the robustness of the proposed MIMO antenna system. more...
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- 2023
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10. Identification of Oil Produced from Shale and Tight Reservoirs in the Permian Lucaogou Shale Sequence, Jimsar Sag, Junggar Basin, NW China
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Lianhua Hou, Xia Luo, Zhongying Zhao, and Lijun Zhang
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Chemistry ,QD1-999 - Published
- 2021
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11. Facile Preparation of Self-Assembled Chitosan-Based POSS-CNTs-CS Composite as Highly Efficient Dye Absorbent for Wastewater Treatment
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Hongjie Zhao, Ran Wang, Huizhen Deng, Lijun Zhang, Lili Gao, Lexin Zhang, and Tifeng Jiao
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Chemistry ,QD1-999 - Published
- 2020
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12. Features and Commercial Performance of a System of Biomass Gasification for Simultaneous Clean Heating and Activated Carbon Production
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Jianbin Zhou, Liangcai Wang, Pengyuan Zhang, Yu Chen, Lijun Zhang, Huanhuan Ma, Yimeng Zhang, and Dengyu Chen
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Chemistry ,QD1-999 - Published
- 2020
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13. A Novel Methodology for Predicting the Production of Horizontal CSS Wells in Offshore Heavy Oil Reservoirs Using Particle Swarm Optimized Neural Network
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Lijun Zhang, Haojun Xie, Zehua Fan, Yuting Bai, Jinpeng Hu, Chengkai Wang, and Xiaofei Sun
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offshore heavy oil reservoirs ,cyclic steam stimulation ,particle swarm optimization algorithm ,long short-term memory model ,cumulative oil production ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Cyclic steam stimulation (CSS) is one of the main offshore heavy oil recovery methods used. Predicting the production of horizontal CSS wells is significant for developing offshore heavy oil reservoirs. Currently, the existing reservoir numerical simulation and analytical models are the two major methods to predict the production of horizontal CSS wells. The reservoir numerical simulation method is tedious and time-consuming, while the analytical models need many assumptions, decreasing models’ accuracy. Therefore, in this study, a novel methodology combining the particle swarm optimization algorithm (PA) and long short-term memory (LM) model was developed to predict the production of horizontal CSS wells. First, a simulation model was established to calculate the cumulative oil production (COP) of horizontal CSS wells under different well, geological, and operational parameters, and then the correlations between the calculated COP and parameters were analyzed by Pearson correlation coefficient to select the input variables and to generate the initial data set. Then, a PA-LM model for the COP of horizontal CSS wells was developed by utilizing the PA to determine the optimal hyperparameters of the LM model. Finally, the accuracy of the PA-LM model was validated by the initial data set and actual production data. The results showed that, compared with the LM model, the mean absolute percentage error (MAPE) of the testing set for the PA-LM model decreased by 4.27%, and the percentage of the paired points in zone A increased by 2.8% in the Clarke error grids. In addition, the MAPEs of the training set for the PA-LM and LM models stabilized at 267 and 304 epochs, respectively. Therefore, the proposed PA-LM model had a higher accuracy, a stronger generalization ability, and a faster convergence rate. The MAPEs of the actual and predicted COP of the wells B1H and B5H by the optimized PA-LM model were 8.66% and 5.93%, respectively, satisfying the requirements in field applications. more...
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- 2023
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14. Engineering Magnetosomes for High-Performance Cancer Vaccination
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Feng Li, Weidong Nie, Fan Zhang, Guihong Lu, Chengliang Lv, Yanlin Lv, Weier Bao, Lijun Zhang, Shuang Wang, Xiaoyong Gao, Wei Wei, and Hai-Yan Xie
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Chemistry ,QD1-999 - Published
- 2019
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15. A Design for a Wide-Band Antenna Pair Applied for Mobile Terminals at the Sub-6 GHz Band
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Yao Hu, Kaiwen Du, Lijun Zhang, Yongshun Wang, and Xiaoming Kang
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antenna pairs ,DGS ,MIMO system ,mobile terminals ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
To meet the requirements of a high transmission rate and strong communication quality for mobile terminals, a planar antenna printed on a 0.8-mm-thick FR-4 substrate is proposed in this paper. The structures are compact, with a size of 23×6 mm2. The performance of a single antenna pair in a 75×35 mm2 ground plane shows the advantages of both ultra-wide bandwidth and high isolation. The operating frequency of −6 dB is 54% (3.3 GHz–5.9 GHz). To solve the mutual coupling effects exiting in the antenna pair, a hybrid strip defected grounding structure (DGS) is added in the middle of neighboring antenna elements, and good isolation performance of lower than −13 dB is achieved. The evolution and analysis of the proposed antenna pair are given to investigate the operating principle. To verify its practicality, an eight-port antenna system in 150×70 mm2 ground plane is constructed along two frames of the smartphone board. The MIMO antenna system performance is simulated and texted. The results show a bandwidth of 3.4–5.2 GHz (−6 dB), an isolation performance lower than −10 dB, an ECC lower than 0.01, and a total efficiency of 46–84%. In addition, the performance of the antenna system under single handheld conditions is also discussed. The correlation results show that the designed antenna pair has good data transmission and interference resistance capability, which proves that this is an excellent antenna model for application in mobile terminals. more...
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- 2022
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16. Identification and Functional Characterization of the RcFAH12 Promoter from Castor Bean in Arabidopsis thaliana
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Jianjun Di, Guorui Li, Xiaoyu Wang, Fenglan Huang, Yongsheng Chen, Yue Wang, Jiaxin Sun, Chunlin Zhang, Qingbo Zhang, Gang Wang, and Lijun Zhang
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castor bean ,promoter ,oleoyl-12-hydroxylase ,RACE ,multiple transcriptional start sites ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Castor (Ricinus communis L.) seed oil is the commercial source of ricinoleate, a valuable raw material used in many industries. Oleoyl-12-hydroxylase (RcFAH12) is a key enzyme in the biosynthesis of ricinoleate, accumulating nearly 90% of the triacylglycerol in castor seeds. Little is known about the transcriptional regulation of RcFAH12. We used rapid amplification of cDNA 5′ ends (5′RACE) to locate the transcription start site (TSS) of RcFAH12, and the sequence of a 2605 bp region, −2506~+99, surrounding the TSS was cloned. We then investigated these regions to promote β-glucuronidase (GUS) expression in transgenic Arabidopsis by the progressive 5′ and 3′ deletions strategies. The GUS staining showed that the GUS accumulation varied in tissues under the control of different deleted fragments of RcFAH12. In addition, the GUS expression driven by the RcFAH12 promoter markedly accumulated in transgenic seeds, which indicated that RcFAH12 might play an important role in the biosynthesis of ricinoleic acid. This study will lay a potential foundation for developing a tissue-specific promoter in oil-seed crops. more...
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- 2022
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17. Thermal Transport in Extremely Confined Metallic Nanostructures: TET Characterization
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Huan Lin, Fuhua Shen, Jinbo Xu, Lijun Zhang, Shen Xu, Na Liu, and Siyi Luo
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ultra-thin metallic materials ,thermal diffusivity ,thermal conductivity ,nanostructures ,TET ,Chemistry ,QD1-999 - Abstract
In recent years, the continuous development of electronic chips and the increasing integration of devices have led to extensive research on the thermal properties of ultrathin metallic materials. In particular, accurate characterization of their thermal transport properties has become a research hotspot. In this paper, we review the characterization methods of metallic nanomaterials, focusing on the principles of the transient electrothermal (TET) technique and the differential TET technique. By using the differential TET technique, the thermal conductivity, electrical conductivity, and Lorenz number of extremely confined metallic nanostructures can be characterized with high measurement accuracy. At present, we are limited by the availability of existing coating machines that determine the thickness of the metal films, but this is not due to the measurement technology itself. If a material with a smaller diameter and lower thermal conductivity is used as the substrate, much thinner nanostructures can be characterized. more...
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- 2022
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18. Experimental Measurements and Numerical Simulation of H2S Generation during Cyclic Steam Stimulation Process of Offshore Heavy Oil from Bohai Bay, China
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Taichao Wang, Renfeng Yang, Lijun Zhang, Wei Zheng, Yan Sun, and Yuting Bai
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offshore heavy oil ,cyclic steam stimulation ,aquathermolysis ,numerical simulation ,hydrogen sulfide ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Cyclic steam stimulation (CSS) is successfully applied to increase heavy oil recovery in heavy oil reservoirs in Bohai Bay, China. However, during the CSS processes, hydrogen sulfide (H2S) was detected in some heavy oil reservoirs. The existing literature mainly focused on the H2S generation of onshore heavy oil. There is no concrete experimental data available, especially about the level of H2S generation during CSS of offshore heavy oil. In addition, there is still a lack of effective reaction kinetic models and numerical simulation methods to simulate H2S generation during the CSS of offshore heavy oil. Therefore, this paper presents a case study from Bohai Bay, China. First, the laboratory aquathermolysis tests were conducted to simulate the gases that are produced during the CSS processes of heavy oil. The effects of the reaction temperature and time on the H2S generation were studied. Then, a one-dimensional CSS experiment was performed to predict H2S generation under reservoir conditions. A kinetic model for the prediction of H2S generation during the CSS of heavy oil was presented. The developed model was calibrated with the experimental data of the one-dimensional CSS experiment at a temperature of 300 °C. Finally, a reservoir model was developed to predict H2S generation and investigate the effects of soaking time, steam quality, and steam injection volume on H2S generation during CSS processes. The results show that the H2S concentration increased from 0.77 ppm in the first cycle to 1.94 ppm in the eighth cycle during the one-dimensional CSS experiment. The average absolute error between the measured and simulated H2S production was 12.46%, indicating that the developed model can accurately predict H2S production. The H2S production increase with soaking time, steam quality, and steam injection volume due to the strengthened aquathermolysis reaction. Based on the reservoir simulation, the H2S production was predicted in the range of 228 m3 to 2895 m3 within the parameters of this study. more...
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- 2022
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19. Design, Synthesis and Characterization of Bitumen Emulsifiers Based on Molecular Simulation
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Xiangjun Kong, Jinlan Wang, Zupei Liang, Lijun Zhang, and Junhe Zhao
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molecular simulation ,bitumen ,emulsifier ,emulsified bitumen ,Chemistry ,QD1-999 - Abstract
Under the guidance of molecular simulation technology, the Monte Carlo molecular mechanics simulation was used to calculate the compatibility of different lipophilic groups with each component of bitumen, and the compatibility of different hydrophilic groups with water. Based on the calculated results of interaction parameters Chi and mixture energy Emix, the preferred structures of lipophilic and hydrophilic groups of bitumen emulsifier were determined. The target bitumen emulsifier was then synthesized by the reaction of organic acid and polyamine. The molecular simulation results showed that the compatibility of lipophilic group T11 with the bitumen was the best, and the mixing ability of the hydrophilic group H5 with water was excellent. The experimental results show that the preferred structures T11H5 had a good emulsifying performance to prepare emulsified bitumen with good storage stability, consistent with the results of the molecular simulation. more...
- Published
- 2019
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20. Effects of Current Annealing on Thermal Conductivity of Carbon Nanotubes
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Huan Lin, Jinbo Xu, Fuhua Shen, Lijun Zhang, Shen Xu, Hua Dong, and Siyi Luo
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carbon nanotubes ,current annealing ,thermal conductivity ,graphitization ,Chemistry ,QD1-999 - Abstract
This work documents the annealing effect on the thermal conductivity of nanotube film (CNTB) and carbon nanotube fiber (CNTF). The thermal properties of carbon nanotube samples are measured by using the transient electro-thermal (TET) technique, and the experimental phenomena are analyzed based on numerical simulation. During the current annealing treatment, CNTB1 always maintains the negative temperature coefficient of resistance (TCR), and its thermal diffusivity increases gradually. When the annealing current is 200 mA, it increases by 33.62%. However, with the increase of annealing current, the TCR of CNTB2 changes from positive to negative. The disparity between CNTB2 and CNTB1 suggests that they have different physical properties and even structures along their lengths. The high-level thermal diffusivity of CNTB2 and CNTF are 2.28–2.46 times and 1.65–3.85 times higher than the lower one. The results show that the decrease of the thermal diffusivity for CNTB2 and CNTF is mainly caused by enhanced Umklapp scattering, the high thermal resistance and torsional sliding during high temperature heating. more...
- Published
- 2021
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21. Time-Domain Sound Field Reproduction with Pressure and Particle Velocity Jointly Controlled
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Xuanqi Hu, Jiale Wang, Wen Zhang, and Lijun Zhang
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sound field reproduction ,pressure matching ,particle velocity ,time domain ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Particle velocity has been introduced to improve the performance of spatial sound field reproduction systems with an irregular loudspeaker array setup. However, existing systems have only been developed in the frequency domain. In this work, we propose a time-domain sound field reproduction method with both sound pressure and particle velocity components jointly controlled. To solve the computational complexity problem associated with the multi-channel setup and the long-length filter design, we adopt the general eigenvalue decomposition-based approach and the conjugate gradient method. The performance of the proposed method is evaluated through numerical simulations with both a regular loudspeaker array layout and an irregular loudspeaker array layout in a room environment. more...
- Published
- 2021
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22. Online Blended Learning in Small Private Online Course
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Yong Han, Wenjun Wu, Lijun Zhang, and Yu Liang
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peer grading ,blended learning ,online experiment platform ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
In this work, we studied the online blended learning model of computer network experimentation, focusing mainly on the problem of traditional network experiments being limited by location and time, and explore the applicability of the small private online course (SPOC) advanced teaching concepts to computer network online experiment teaching. Based on the structure of a combination of virtual and real, real and not virtual, an online network experiment platform and management system has been designed and constructed, enabling students to carry out remote online computer network hardware experiments anytime and anywhere, without being restricted by time, space, or content. Using the online network experiment platform, we can organize the experimental modules and knowledge points via the SPOC course concept, by developing online network experimental content, modularizing and fragmenting of the experiments, creating the pre-experimental explanation and experiment preview videos, and evaluating the assignments via peer grading to analyze students’ learning behavior. By exploring online network experimental teaching methods and management models, offering experimental guidance in an interactive manner, and highlighting the openness and sharing characteristics of online experimental teaching platforms, we can improve the utilization rate for teaching resources, and provide ideas for applied scientific research methods. more...
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- 2021
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23. On the Potential Contributions of Matrix Converters for the Future Grid Operation, Sustainable Transportation and Electrical Drives Innovation
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Alexandre Bento, Guilherme Paraíso, Pedro Costa, Lijun Zhang, Thomas Geury, Sónia Ferreira Pinto, and José Fernando Silva
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AC-AC converters ,smart grids ,solid state transformers ,renewable energy ,energy storage ,V2G and G2V ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Matrix converters have been extensively investigated in academia over the last 3 decades. Several review works targeting matrix converter topologies, commutation strategies, modulation and control techniques have been published. However, to the best of the authors’ knowledge, a review on the potential contributions of matrix converters for applications that are shaping the electric power sector transition towards decarbonization is lacking, namely applications on smart grids, sustainable transportation and electrical drives. This paper presents an extensive literature review on the more relevant research works targeting applications of matrix converters as an enabling key technology for smart and resilient grids, sustainable transportation, and innovation in variable speed electric drives. more...
- Published
- 2021
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24. Full-Color Realization of Micro-LED Displays
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Yifan Wu, Jianshe Ma, Ping Su, Lijun Zhang, and Bizhong Xia
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micro-LED ,full-color display ,mass transfer ,color conversion ,monolithic growth ,Chemistry ,QD1-999 - Abstract
Emerging technologies, such as smart wearable devices, augmented reality (AR)/virtual reality (VR) displays, and naked-eye 3D projection, have gradually entered our lives, accompanied by an urgent market demand for high-end display technologies. Ultra-high-resolution displays, flexible displays, and transparent displays are all important types of future display technology, and traditional display technology cannot meet the relevant requirements. Micro-light-emitting diodes (micro-LEDs), which have the advantages of a high contrast, a short response time, a wide color gamut, low power consumption, and a long life, are expected to replace traditional liquid-crystal displays (LCD) and organic light-emitting diodes (OLED) screens and become the leaders in the next generation of display technology. However, there are two major obstacles to moving micro-LEDs from the laboratory to the commercial market. One is improving the yield rate and reducing the cost of the mass transfer of micro-LEDs, and the other is realizing a full-color display using micro-LED chips. This review will outline the three main methods for applying current micro-LED full-color displays, red, green, and blue (RGB) three-color micro-LED transfer technology, color conversion technology, and single-chip multi-color growth technology, to summarize present-day micro-LED full-color display technologies and help guide the follow-up research. more...
- Published
- 2020
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25. Comparative Research on RC Equivalent Circuit Models for Lithium-Ion Batteries of Electric Vehicles
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Lijun Zhang, Hui Peng, Zhansheng Ning, Zhongqiang Mu, and Changyan Sun
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lithium-ion batteries ,equivalent circuit model ,electric vehicles ,parameter identification ,battery management system ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Equivalent circuit models are a hot research topic in the field of lithium-ion batteries for electric vehicles, and scholars have proposed a variety of equivalent circuit models, from simple to complex. On one hand, a simple model cannot simulate the dynamic characteristics of batteries; on the other hand, it is difficult to apply a complex model to a real-time system. At present, there are few systematic comparative studies on equivalent circuit models of lithium-ion batteries. The representative first-order resistor-capacitor (RC) model and second-order RC model commonly used in the literature are studied comparatively in this paper. Firstly, the parameters of the two models are identified experimentally; secondly, the simulation model is built in Matlab/Simulink environment, and finally the output precision of these two models is verified by the actual data. The results show that in the constant current condition, the maximum error of the first-order RC model is 1.65% and the maximum error for the second-order RC model is 1.22%. In urban dynamometer driving schedule (UDDS) condition, the maximum error of the first-order RC model is 1.88%, and for the second-order RC model the maximum error is 1.69%. This is of great instructional significance to the application in practical battery management systems for the equivalent circuit model of lithium-ion batteries of electric vehicles. more...
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- 2017
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26. Effects of Vibration on the Electrical Performance of Lithium-Ion Cells Based on Mathematical Statistics
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Lijun Zhang, Zhansheng Ning, Hui Peng, Zhongqiang Mu, and Changyan Sun
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lithium-ion battery ,vibration load ,electrical degradation ,mathematical statistic ,consistency analysis ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Lithium-ion batteries are increasingly used in mobile applications where mechanical vibrations and shocks are a constant companion. There is evidence both in the academic and industrial communities to suggest that the electrical performance and mechanical properties of the lithium-ion cells of an electric vehicle (EV) are affected by the road-induced vibration. However, only a few studies related to the effects of vibration on the degradation of electrical performance of lithium-ion batteries have been approached. Therefore, this paper aimed to investigate the effects of vibration on the DC resistance, 1C capacity and consistency of NCR18650BE lithium-ion cells. Based on mathematical statistics, the method changes of the DC resistance and the capacity of the cells both before and after the test were analyzed with a large sample size. The results identified that a significant increase in DC resistance was observed as a result of vibration at the 95% confidence level, while typically a reduction in 1C capacity was also noted. In addition, based on a multi-feature quantity, a clustering algorithm was adopted to analyze the effect of vibration on cell consistency; the results show that the cell consistency had deteriorated after the vibration test. more...
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- 2017
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27. Electrical Energy Forecasting and Optimal Allocation of ESS in a Hybrid Wind-Diesel Power System
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Hai Lan, He Yin, Shuli Wen, Ying-Yi Hong, David C. Yu, and Lijun Zhang
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renewable energy ,energy storage system ,hybrid multi-objective particle swarm optimization ,back-propagation neural network ,power-voltage sensitivity analysis ,three-point estimation method ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Due to the increasingly serious energy crisis and environmental pollution problem, traditional fossil energy is gradually being replaced by renewable energy in recent years. However, the introduction of renewable energy into power systems will lead to large voltage fluctuations and high capital costs. To solve these problems, an energy storage system (ESS) is employed into a power system to reduce total costs and greenhouse gas emissions. Hence, this paper proposes a two-stage method based on a back-propagation neural network (BPNN) and hybrid multi-objective particle swarm optimization (HMOPSO) to determine the optimal placements and sizes of ESSs in a transmission system. Owing to the uncertainties of renewable energy, a BPNN is utilized to forecast the outputs of the wind power and load demand based on historic data in the city of Madison, USA. Furthermore, power-voltage (P-V) sensitivity analysis is conducted in this paper to improve the converge speed of the proposed algorithm, and continuous wind distribution is discretized by a three-point estimation method. The Institute of Electrical and Electronic Engineers (IEEE) 30-bus system is adopted to perform case studies. The simulation results of each case clearly demonstrate the necessity for optimal storage allocation and the efficiency of the proposed method. more...
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- 2017
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28. ZIF-derived hierarchical pore carbons as high-performance catalyst for methane decomposition
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Shun Zhao, Lijun Zhang, Haoquan Hu, Lijun Jin, Yunfei Wu, and Yun Zhang
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Methane decomposition ,chemistry.chemical_compound ,Materials science ,chemistry ,Chemical engineering ,Carbonization ,Specific surface area ,Carbon source ,chemistry.chemical_element ,Carbon ,Methane ,Furfuryl alcohol ,Catalysis - Abstract
Catalytic methane decomposition (CMD) is a promising route for H2 production. In this paper, MOF-derived hierarchical carbon catalysts were prepared by the carbonization of ZIF-8 with additional carbon source and used for CMD. The effects of carbonization temperature, reaction temperature, and the kinds of additional carbon sources on the structure of derived carbon materials and their catalytic performances were studied. The results showed that the morphology and textural properties can be improved by varying the carbonization temperature and additional carbon source. The specific surface area of the ZIF-derived carbon can be significantly increased, and the hierarchical pore structure with improved pore size distribution can be obtained, which leads to good performances for CMD. Catalytic performance can be obviously enhanced by increasing the reaction temperature. The C950-FA prepared by carbonization of ZIF-8 with furfuryl alcohol as additional carbon source exhibits the highest initial conversion of methane (64%) and good stability at 890 °C. About 11% methane conversion was kept after 2750 min. This study provides a new route for the preparation of carbon material catalysts to achieve high-efficient conversion of methane. more...
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- 2022
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29. Co-pyrolysis of coke bottle wastes with cellulose, lignin and sawdust: Impacts of the mixed feedstock on char properties
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Xun Hu, Chao Li, Zijun Yi, Yifan Sun, Shu Zhang, and Lijun Zhang
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Renewable Energy, Sustainability and the Environment ,Chemistry ,Biomass ,Coke ,Raw material ,chemistry.chemical_compound ,Chemical engineering ,visual_art ,visual_art.visual_art_medium ,Lignin ,Sawdust ,Char ,Cellulose ,Pyrolysis - Abstract
Co-pyrolysis of coke bottle (CB) with sawdust/cellulose/lignin was conducted at 700 °C in this study, aiming to understand the potential influence of interactions of the volatiles of the varied origins on properties of the char. The results indicated that the interaction of volatiles from CB with that from biomass enhanced cross-polymerization of the volatiles, decreasing the formation of gases while enhanced the formation of both char and oil. The cross-interactions of the intermediates also diminished the formation of π-conjugated organics. In addition, the varied volatiles from the pyrolysis of cellulose, lignin, or sawdust interacted with that from CB and affected the properties of char in different ways. The char from the co-pyrolysis of sawdust/CB was more aliphatic, and had a higher oxygen content (7.3%) and higher polarity but lower thermal stability. Additionally, the thermal stability, crystallinity as well as the evolution of functionalities of char versus increasing temperature were also significantly affected by the cross-interactions of the volatiles. more...
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- 2022
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30. Microchamber-Free Digital Flow Cytometric Analysis of T4 Polynucleotide Kinase Phosphatase Based on Single-Enzyme-to-Single-Bead Space-Confined Reaction
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Wenjiao Fan, Chenghui Liu, Wei Ren, Lijun Zhang, Dailu Jia, and Qinya Feng
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chemistry.chemical_classification ,Polynucleotide 5'-Hydroxyl-Kinase ,Biomolecule ,Phosphatase ,Nanotechnology ,Microbead (research) ,Fluorescence ,Phosphoric Monoester Hydrolases ,Analytical Chemistry ,Enzyme ,chemistry ,Digital signal ,T4 polynucleotide kinase ,Sensing system - Abstract
Digital bioassays have attracted extensive attention in biomedical applications due to their ultrahigh sensitivity. However, traditional digital bioassays require numerous microchambers such as droplets or microwells, which restricts their application scope. Herein, we propose a microchamber-free flow cytometric method for the digital quantification of T4 polynucleotide kinase phosphatase (T4 PNKP) based on an unprecedented phenomenon that each T4 PNKP molecule-catalyzed reaction can be spatially self-confined on a single microbead, which ultimately enables the one-target-to-one-fluorescence-positive microbead digital signal transduction. The digital signal-readout mode can clearly detect T4 PNKP concentrations as low as 1.28 × 10-10 U/μL, making it most sensitive method to date. Significantly, T4 PNKP can be specifically distinguished from other phosphatases and nucleases in complex samples by digitally counting the fluorescence-positive microbeads, which cannot be realized by traditional bulk measurement-based methods. Taking advantage of the novel space-confined enzymatic feature of T4 PNKP, this digital mechanism can use T4 PNKP as the enzyme label to fabricate digital sensing systems toward various biomolecules such as digital enzyme-linked immunosorbent assay (ELISA). Therefore, this work not only enlarges the toolbox for high-sensitivity biomolecule detection but also opens new gates to fabricate next-generation digital assays. more...
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- 2021
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31. Syntheses of Rare-Earth Metal Alkyl Complexes Bearing a Dianionic α-Iminopyridyl Ligand and Their Catalytic Activities toward Polymerization of 2-Vinylpyridine
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Gen Luo, Xiancui Zhu, Donghan Wang, Xiuli Zhang, Yun Wei, Peng Cui, Lijun Zhang, Shuangliu Zhou, and Shaowu Wang
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chemistry.chemical_classification ,2-Vinylpyridine ,Bearing (mechanical) ,Chemistry ,Ligand ,Organic Chemistry ,Rare earth ,Catalysis ,law.invention ,Inorganic Chemistry ,Metal ,chemistry.chemical_compound ,Polymerization ,law ,visual_art ,Polymer chemistry ,visual_art.visual_art_medium ,Physical and Theoretical Chemistry ,Alkyl - Published
- 2021
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32. Survival outcomes in older men with non-metastatic castration-resistant prostate cancer treated with androgen receptor inhibitors: a US Food and Drug Administration pooled analysis of patient-level data from three randomised trials
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Sundeep Agrawal, Anup K. Amatya, Harpreet Singh, Lijun Zhang, Mehrnoosh Hadadi, Vishal Bhatnagar, Amna Ibrahim, Paul G. Kluetz, Bellinda L. King-Kallimanis, Julia A. Beaver, Shenghui Tang, Yutao Gong, Michael Brave, Mitchell S. Anscher, Chana Weinstock, Jaleh Fallah, Elaine Chang, Laleh Amiri-Kordestani, Richard Pazdur, James X Xu, Dow-Chung Chi, Daniel L. Suzman, Jamie R. Brewer, Marc R. Theoret, and Kirsten B. Goldberg more...
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Male ,medicine.medical_specialty ,Drug-Related Side Effects and Adverse Reactions ,Placebo ,Prostate cancer ,chemistry.chemical_compound ,Internal medicine ,Androgen Receptor Antagonists ,Humans ,Medicine ,Enzalutamide ,Progression-free survival ,Neoplasm Metastasis ,Survival rate ,Aged ,Randomized Controlled Trials as Topic ,Aged, 80 and over ,United States Food and Drug Administration ,business.industry ,Apalutamide ,Hazard ratio ,medicine.disease ,Progression-Free Survival ,United States ,Survival Rate ,Androgen receptor ,Prostatic Neoplasms, Castration-Resistant ,Oncology ,chemistry ,Quality of Life ,business - Abstract
Little is known about the benefit-risk profile of second-generation androgen receptor inhibitors in older men with non-metastatic castration-resistant prostate cancer. We aimed to examine the efficacy and safety of second-generation androgen receptor inhibitors in men aged 80 years or older with non-metastatic castration-resistant prostate cancer.We searched for all randomised controlled clinical trials evaluating second-generation androgen receptor inhibitors in patients with non-metastatic castration-resistant prostate cancer submitted to the US Food and Drug Administration before Aug 15, 2020, and pooled data from three trials that met the selection criteria. All three trials enrolled patients who were aged 18 years or older with an Eastern Cooperative Oncology Group performance status of 0-1, castration-resistant prostate cancer, prostate-specific antigen (PSA) 2·0 μg/L or greater, PSA doubling time of 10 months or less, and no evidence of distant metastatic disease on conventional imaging per the investigator's assessment at the time of screening. All patients had histologically or cytologically confirmed adenocarcinoma of the prostate without neuroendocrine differentiation or small-cell features. All patients who were randomly assigned to androgen receptor inhibitor or placebo groups in these trials were considered assessable and were included in this pooled analysis. We evaluated the effect of age on metastasis-free survival and overall survival across age groups (80 years vs ≥80 years) in the intention-to-treat population. Safety analyses were done in patients who received at least one dose of study treatment.Between Oct 14, 2013, and March 9, 2018, 4117 patients were assigned to androgen receptor inhibitor (apalutamide, enzalutamide, or daralutamide; n=2694) or placebo (n=1423) across three randomised trials. The median follow-up duration for metastasis-free survival was 18 months (IQR 11-26) and for overall survival was 44 months (32-55). In patients aged 80 years or older (n=1023), the estimated median metastasis-free survival was 40 months (95% CI 36-41) in the androgen receptor inhibitor groups and 22 months (18-29) in the placebo groups (adjusted hazard ratio [HR] 0·37 [95% CI 0·28-0·47]), and the median overall survival was 54 months (50-61) versus 49 months (43-58), respectively (adjusted HR 0·79 [0·64-0·98]). In patients younger than 80 years of age (n=3094), the estimated median metastasis-free survival was 41 months (95% CI 36-not estimable [NE]) in the androgen receptor inhibitor groups and 16 months (15-18) in the placebo groups (adjusted HR 0·31 [95% CI 0·27-0·35]), and the median overall survival was 74 months (74-NE) versus 61 months (56-NE), respectively (adjusted HR 0·69 [0·60-0·80]). In patients aged 80 years or older, grade 3 or worse adverse events were reported in 371 (55%) of 672 patients in the androgen receptor inhibitor groups and 140 (41%) of 344 patients in the placebo groups, compared with 878 (44%) of 2015 patients in the androgen receptor inhibitor groups and 321 (30%) of 1073 patients in the placebo groups among patients younger than 80 years. The most common grade 3-4 adverse events were hypertension (168 [8%] of 2015 patients aged80 years and 51 [8%] of 672 patients aged ≥80 years in the androgen receptor inhibitor groups vs 53 [5%] of 1073 patients aged80 years and 22 [6%] of 344 patients aged ≥80 years in the placebo groups) and fracture (61 [3%] and 36 [5%] in the androgen receptor inhibitor groups vs 15 [1%] and 11 [3%] in the placebo groups).The findings of this pooled analysis support the use of androgen receptor inhibitors in older men with non-metastatic castration-resistant prostate cancer. Incorporating geriatric assessment tools in the care of older adults with non-metastatic castration-resistant prostate cancer might help clinicians to offer individualised treatment to each patient.None. more...
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- 2021
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33. Competition between acidic sites and hydrogenation sites in Cu/ZrO2 catalysts with different crystal phases for conversion of biomass-derived organics
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Qingyin Li, Yuewen Shao, Guangzhi Hu, Shu Zhang, Xun Hu, Kai Sun, Zhanming Zhang, Lijun Zhang, and Tingting Wang
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Renewable Energy, Sustainability and the Environment ,Inorganic chemistry ,chemistry.chemical_element ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Furfural ,01 natural sciences ,Copper ,0104 chemical sciences ,Catalysis ,Furfuryl alcohol ,law.invention ,chemistry.chemical_compound ,Tetragonal crystal system ,chemistry ,law ,Cubic zirconia ,Calcination ,0210 nano-technology ,Monoclinic crystal system - Abstract
Oxides with different crystal phases can have important effects on the configuration of surface atoms, which can further affect the distribution of hydrogenation sites and acidic sites as well as the competitions of these varied types of catalytic sites. This could be potentially used to tailor the distribution of the products. In this study, zirconium oxides with different crystal phases supported copper catalysts were prepared for the hydrogenation of the biomass-derived furfural, vanillin, etc. The results showed that both calcination temperature and Cu species affected the shift of zirconia from tetragonal phase to the monoclinic phase. Monoclinic zirconia supported copper catalyst can effectively catalyze the hydrogenation of furfural to furfuryl alcohol via hydrogenation route due to its low amount of Bronsted acidic sites, although the surface area and the exposed metallic Cu surface area were much lower than the tetragonal zirconia supported copper catalyst. Zirconia with tetragonal or tetragonal/monoclinic phases supported copper catalysts contain abundant acidic sites and especially the Bronsted acidic sites, which catalyzed mainly the conversion of furfural via the acid-catalyzed routes such as the acetalization, rather than the hydrogenation. The acidic sites over the Cu/ZrO2 catalyst played more predominant roles than the hydrogenation sites in determining the conversion of the organics like furfural and vanillin. more...
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- 2021
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34. Association of Genetic Variants in miR-217 Gene with Risk of Coronary Artery Disease: A Case–Control Study
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Menghai Wu, Lijun Zhang, Xiaotang Liang, Honglei Jiang, and Xia Han
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Oncology ,medicine.medical_specialty ,miR-217 ,Pathogenesis ,Coronary artery disease ,chemistry.chemical_compound ,symbols.namesake ,Pharmacogenomics and Personalized Medicine ,Internal medicine ,Medicine ,SNP ,Allele ,Gene ,Original Research ,Pharmacology ,business.industry ,Case-control study ,medicine.disease ,VEGF ,Vascular endothelial growth factor ,Bonferroni correction ,chemistry ,symbols ,Molecular Medicine ,genetic ,business ,coronary artery disease - Abstract
Xia Han,1,* Xiaotang Liang,2,* Menghai Wu,1 Lijun Zhang,1 Honglei Jiang2 1Department of Cardiology, Jinan Peopleâs Hospital Affiliated to Shandong First Medical University, Laiwu, 271199, Peopleâs Republic of China; 2Shandong Second Provincial General Hospital, Jinan, Shandong Province, 250000, Peopleâs Republic of China*These authors contributed equally to this workCorrespondence: Honglei JiangShandong Second Provincial General Hospital, No. 4, Xingxi Street, Jinan, Shandong Province, 250000, Peopleâs Republic of ChinaEmail jianghl_sd@21cn.comObjective: To evaluate the associations of genetic variants of the miR-217 gene with coronary artery disease (CAD) risk, as well as plasma level of vascular endothelial growth factor (VEGF).Methods: A caseâcontrol study with 498 CAD patients and 499 frequency-matched healthy controls was conducted to evaluate the associations of four tagSNPs of the miR-217 gene, including rs6724872, rs4999828, rs10206823, and rs41291177, with CAD risk and plasma level of VEGF.Results: SNP rs6724872 and rs4999828 were significantly associated with increased risk of CAD (P value was smaller than 0.05 even after Bonferroni multiple adjustment). Compared with the G allele, C allele of rs6724872 was significantly associated with 1.73-fold increased risk of CAD (95% CI: 1.25â 2.39; P = 0.001). While C allele of rs4999828 was significantly associated with 1.75-fold increased risk of CAD, compared with T allele (95% CI: 1.34â 2.29; P = 4 Ã 10â 5). Meanwhile, rs6724872 and rs4999828 were also significantly associated with higher level of VEGF (P < 0.001).Conclusion: These findings highlighted the important role of genetic variants of the miR-217 gene in the pathogenesis of CAD and potential targets for intervention.Keywords: coronary artery disease, miR-217, VEGF, genetic more...
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- 2021
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35. Stable Cesium-Rich Formamidinium/Cesium Pure-Iodide Perovskites for Efficient Photovoltaics
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Xingtao Wang, Miao Kan, Xiaomin Liu, Xinjiang Wang, Yong Wang, Yanfeng Miao, Yuetian Chen, Xiaoyu Wang, Yixin Zhao, Haoran Chen, Jielin Shi, Taiyang Zhang, and Lijun Zhang
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chemistry.chemical_classification ,Materials science ,Renewable Energy, Sustainability and the Environment ,business.industry ,Iodide ,Inorganic chemistry ,Energy Engineering and Power Technology ,chemistry.chemical_element ,Fuel Technology ,Formamidinium ,chemistry ,Chemistry (miscellaneous) ,Photovoltaics ,Caesium ,Materials Chemistry ,business - Published
- 2021
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36. Selective Conversion of Furfural into Diols over Co-Based Catalysts: Importance of the Coordination of Hydrogenation Sites and Basic Sites
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Xiangzhou Yuan, Kai Sun, Mingzhu Guo, Yuewen Shao, Guangzhi Hu, Xun Hu, Lijun Zhang, Shu Zhang, Junzhe Wang, and Leilei Xu
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chemistry.chemical_compound ,Chemistry ,General Chemical Engineering ,Organic chemistry ,General Chemistry ,Furfural ,Industrial and Manufacturing Engineering ,Catalysis - Published
- 2021
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37. Stability analysis on the kerosene nanofluid flow with hybrid zinc/aluminum-oxide (ZnO-Al2O3) nanoparticles under Lorentz force
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Muhammad Mubashir Bhatti, Tayyaba Nazar, Efstathios E. Michaelides, and Lijun Zhang
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Kerosene ,Materials science ,Applied Mathematics ,Mechanical Engineering ,Flow (psychology) ,chemistry.chemical_element ,02 engineering and technology ,Zinc ,01 natural sciences ,010305 fluids & plasmas ,Computer Science Applications ,Magnetic field ,symbols.namesake ,020303 mechanical engineering & transports ,Nanofluid ,0203 mechanical engineering ,chemistry ,Mechanics of Materials ,0103 physical sciences ,symbols ,Al2o3 nanoparticles ,Composite material ,Lorentz force ,Aluminum oxide - Abstract
Purpose The flow and heat transfer of a hybrid nanofluid composed of kerosene and ZnO-Al2O3 nanoparticles (NPs) is investigated. The flow occurs over complex surfaces with stretching and shrinking features. The base fluid is electrically conducting, and an external magnetic field is added so that the nanofluid and the electric field are in equilibrium. Irrotational flow with viscous dissipation effects is considered. Design/methodology/approach The governing equations of the system are formulated, and a similarity transformation is used to convert the system of equations into ordinary differential equations, which are solved numerically. The friction coefficient of the flow and the Nusselt number are calculated for a wide range of parameters, and the results are presented in graphical form. In addition, dual solutions of the problem were noticed to occur for a certain range of the unsteadiness parameter. A stability analysis has been performed and presented to elucidate the behavior of these dual solutions. Findings For the solution of the upper branch, the velocity and temperature profiles of the nanofluid are enhanced by increasing the magnetic field parameter M, but the same variables decrease in the solution of the lower branch. The same trend is detected for the velocity of the fluid with the suction parameter. The temperature of the nanofluid decreases in both branches of the solution by increasing the Prandtl number. Similarly, they decrease with the suction parameter. The temperature of the nanofluid slightly increases in both branches of the solution by increasing the Eckert number. With the stability analysis the authors performed, it was determined that the solution is stable in the upper branch, but unstable in the lower branch. Originality/value The kerosene nanofluid with hybrid Zinc/Aluminum-oxide is presented for the first time in the literature. more...
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- 2021
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38. Hierarchically Grown Ni–Mo–S Modified 2D CeO2 for High-Efficiency Photocatalytic Hydrogen Evolution
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Shanchi Liu, Lijun Zhang, Zhiliang Jin, and Kai Wang
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chemistry.chemical_classification ,Electron mobility ,Sulfide ,010405 organic chemistry ,Chemistry ,Nanoparticle ,General Chemistry ,Overpotential ,010402 general chemistry ,01 natural sciences ,Catalysis ,0104 chemical sciences ,Nanomaterials ,Chemical engineering ,Photocatalysis ,Bimetallic strip - Abstract
Through a simple solvothermal method, the bimetallic sulfide nanomaterial (Ni–Mo–S) was successfully grown on the surface of CeO2 to restrain the severe photogenerated electron–hole recombination of CeO2. The presence of a close contact interface between the 0D metal sulfide particles and the 2D CeO2 sheet is conducive to charge transfer. Meanwhile, the introduction of Ni–Mo–S nanoparticles on 2D CeO2 can accelerate surface electron mobility, which could obviously inhibit the combination of electrons and holes. Also, there are many unsaturation sites of metal sulfide introduced on the surface and low hydrogen evolution overpotential, which can serve as active sites for hydrogen evolution. In addition, the 2D structure of CeO2 can provide a support framework for the 0D Ni–Mo–S particles, thereby greatly reducing the recombination of useful electrons and holes. All of these advantages of photocatalysts discussed above make for the enhancement of photocatalyst catalytic performance, which equal to about 66 times compared with pure CeO2. Besides, a series of research tests were carried out from different angles to support the relevant results and proposed possible reaction mechanisms. more...
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- 2021
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39. Selective hydrogenation of furfural and its derivative over bimetallic NiFe-based catalysts: Understanding the synergy between Ni sites and Ni–Fe alloy
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Xun Hu, Chao Li, Guangzhi Hu, Shu Zhang, Guoming Gao, Junzhe Wang, Yuewen Shao, Kai Sun, Lijun Zhang, and Leilei Xu
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060102 archaeology ,Renewable Energy, Sustainability and the Environment ,020209 energy ,Layered double hydroxides ,chemistry.chemical_element ,06 humanities and the arts ,02 engineering and technology ,engineering.material ,Furfural ,Catalysis ,Furfuryl alcohol ,chemistry.chemical_compound ,Nickel ,Adsorption ,chemistry ,Hydrogenolysis ,Furan ,0202 electrical engineering, electronic engineering, information engineering ,engineering ,0601 history and archaeology ,Nuclear chemistry - Abstract
Pentanediols (1,2-pentanediol and 1,5-pentanediol) are important feedstock for synthesis of fine chemicals, production of which from the biomass-derived furfural or furfuryl alcohol (FA) has been considered as a sustainable route and attracted much interest. In this study, the catalysts with Ni–Fe as the metal sites and Mg–Al layered double hydroxides (LDH) as precursor of support were synthesized. The results showed that the presence of Fe in catalyst affected both the development of the pores of the catalyst and the catalytic behaviors of nickel species. A low Fe content facilitated formation of mesoporous structure, but the higher content destroyed the LDH structure, resulting in a decreased surface area. Fe could also react with metallic Ni to form NiFe alloy. This decreased the catalytic activity for the further hydrogenation of the furan ring in FA, and FA would thus have the chance to produce pentanediols via hydrogenolysis. The In-situ Diffuse Reflectance Infrared Fourier Transform Spectroscopy characterization of hydrogenation of FA indicated that the alloying between Fe and Ni resulted in a weak adsorption of C C group in furan ring and moderate adsorption of C–O–C group, which suppressed the complete hydrogenation of FA while facilitated the ring-opening of FA to form the pentanediols. more...
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- 2021
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40. 2D CoP supported 0D WO3 constructed S-scheme for efficient photocatalytic hydrogen evolution
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Xin Guo, Lijun Zhang, Teng Yan, Teng Li, and Zhiliang Jin
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Materials science ,Renewable Energy, Sustainability and the Environment ,Phosphide ,Composite number ,Energy Engineering and Power Technology ,Heterojunction ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,0104 chemical sciences ,Catalysis ,Electron transfer ,chemistry.chemical_compound ,Fuel Technology ,Chemical engineering ,Transition metal ,chemistry ,Photocatalysis ,0210 nano-technology ,Hydrogen production - Abstract
For heterojunction composite photocatalyst, intimate contact interface is the key to the carrier transfer separation conditions. Due to the interface contact, the electron transfer rate between catalysts can be increased during photocatalytic hydrogen production, therefore, we design the close contact of 0D/2D heterojunction, which greatly enhanced the photocatalytic hydrogen production activity of the composite catalyst. The composite catalyst WO3/CoP was obtained by simple high temperature in situ synthesis. Moreover, it was proved by photoelectric chemistry and fluorescence tests that appropriate conduction band and valence band locations of WO3 and CoP provided a favorable way for thermodynamic electron transfer. In addition, fluorescence results showed that WO3 load effectively promoted photoelectron-hole transfer and increased electron lifetime. The formation of S-scheme heterojunctions can make more efficient use of useful photogenerated electrons and prevent the photogenerated electron-hole recombination of CoP itself, further promote the liveness of photocatalytic H2 evolution. Meanwhile, the study of Metal-organic frameworks (MOFs) materials further promoted the application of MOFs derivatives in the field of photocatalytic hydrogen evolution, and provided a reference for the rational design of composite catalysts for transition metal phosphide photocatalysts. more...
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- 2021
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41. Hydrogenation of biomass derivatives over Ni/clay catalyst: significant impacts of the treatment of clay with<scp>NaOH</scp>on the reaction network
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Shu Zhang, Lijun Zhang, Leilei Xu, Kai Sun, Guoming Gao, Yuewen Shao, Guangzhi Hu, Xun Hu, and Hongli Tian
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Renewable Energy, Sustainability and the Environment ,General Chemical Engineering ,Vanillin ,Organic Chemistry ,Biomass ,Furfural ,Pollution ,Catalysis ,Inorganic Chemistry ,chemistry.chemical_compound ,Fuel Technology ,chemistry ,Waste Management and Disposal ,Biotechnology ,Nuclear chemistry - Published
- 2021
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42. The small protein MafG plays a critical role in MC3T3-E1 cell apoptosis induced by simulated microgravity and radiation
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Yingjun Tan, Xinsheng Cao, Hai Zhao, Jingjing Dong, Yixuan Wang, Honghui Wang, Lijun Zhang, Zebing Hu, Shu Zhang, Gaozhi Li, and Fei Shi
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MafG Transcription Factor ,0301 basic medicine ,Biophysics ,Down-Regulation ,Apoptosis ,Spaceflight ,Biochemistry ,Cell Line ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,law ,Humans ,Bone damage ,Molecular Biology ,Transcription factor ,Weightlessness Simulation ,chemistry.chemical_classification ,Reactive oxygen species ,Osteoblasts ,Chemistry ,X-Rays ,Cell Biology ,Mc3t3 e1 ,Cell biology ,Repressor Proteins ,030104 developmental biology ,Gene Expression Regulation ,Simulated microgravity ,030220 oncology & carcinogenesis ,Reactive Oxygen Species - Abstract
Microgravity and radiation exposure-induced bone damage is one of the most significant alterations in astronauts after long-term spaceflight. However, the underlying mechanism is still largely unknown. Recent ground-based simulation studies have suggested that this impairment is likely mediated by increased production of reactive oxygen species (ROS) during spaceflight. The small Maf protein MafG is a basic-region leucine zipper-type transcription factor, and it globally contributes to regulation of antioxidant and metabolic networks. Our research investigated the role of MafG in the process of apoptosis induced by simulated microgravity and radiation in MC3T3-E1 cells. We found that simulated microgravity or radiation alone decreased MafG expression and elevated apoptosis in MC3T3-E1 cells, and combined simulated microgravity and radiation treatment aggravated apoptosis. Meanwhile, under normal conditions, increased ROS levels facilitated apoptosis and downregulated the expression of MafG in MC3T3-E1 cells. Overexpression of MafG decreased apoptosis induced by simulated microgravity and radiation. These findings provide new insight into the mechanism of bone damage induced by microgravity and radiation during space flight. more...
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- 2021
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43. Simultaneous determination of 46 semi-volatile organic compounds in water by liquid-liquid extraction-gas chromatography-mass spectrometry
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Chuanming Zhao, Xiaomei Chen, Lijun Zhang, Lingling Liu, and Xiliang Dong
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Detection limit ,Internal standard ,Chromatography ,Chemistry ,General Chemical Engineering ,Organic Chemistry ,Extraction (chemistry) ,Biochemistry ,Analytical Chemistry ,Solvent ,chemistry.chemical_compound ,Liquid–liquid extraction ,Electrochemistry ,Solubility ,Gas chromatography–mass spectrometry ,Dichloromethane - Abstract
Semi-volatile organic compounds (SVOCs) include polycyclic aromatic hydrocarbons (PAHs), phthalic acid esters (PAEs), organochlorine pesticides (OCPs) and nitrobenzenes (NBs). Most of them have carcinogenic, teratogenic, mutagenic and endocrine disrupting effects. Therefore, rapid and accurate determination of SVOCs in water is very important. As the most traditional pretreatment method, liquid-liquid extraction (LLE) has the advantages of wide extraction range, high extraction efficiency, simple operation and lower cost, which is very suitable for the simultaneous extraction of multiclass SVOCs. Dichloromethane has good solubility for most SVOCs, and is slightly soluble in water with low boiling point. It is a good broad-spectrum extractive solvent of organic compounds. But at present, there is no detection standard of SVOCs in water in China. In this study, three factors including nitrogen blowing temperature, pH of water sample and extraction time were optimized. It was aimed to establish a liquid-liquid extraction-gas chromatography-mass spectrometry (GC-MS) method for the simultaneous determination of the 46 SVOCs in water. At first, the effect of nitrogen blowing temperature (30, 35, 40 ℃) was investigated. The results showed that under different nitrogen blowing temperature, the recoveries of the 46 SVOCs were slightly different, but the differences were not significant. Considering the recovery and concentration efficiency, the nitrogen blowing temperature was finally set at 35 ℃. Dichloromethane was selected as the LLE solvent of the SVOCs and its extraction efficiency was investigated. The recoveries of the 46 SVOCs were satisfactory for the determination. Then sample pH (neutral and alkaline condition) was investigated. Most of the SVOCs in this paper have no obvious acid-base property. The extraction effect of water sample under neutral conditions was the best and the most stable, and under alkaline condition, the recovery of each substance was generally low. Finally, extraction time (7, 10, 15 min) was studied. In a certain range, with the increase of extraction time, the recovery also increased, but when the time increased to 15 min, the recovery of some compounds increased or decreased, and the time-consuming was longer, the recovery of most substances could meet the requirements when the extraction time was set to 10 min. The optimized experimental conditions were determined as follows: under neutral conditions, the water sample was extracted by dichloromethane for three times, each extraction time was 10 min, and concentrated at the nitrogen blowing temperature of 35 ℃. GC-MS was used for detection, and internal standard method was used for quantitative analysis. The results showed that the linearity of the method was good in the range of 20-2000 μg/L, the correlation coefficients (r2) were no less than 0.9916, the limits of detection (LODs, S/N=3) ranged from 0.28 to 16.55 ng/L, and the limits of quantification (LOQs, S/N=10) ranged from 0.92 to 55.16 ng/L. The average recovery was 63.6%-125% at three spiked levels of 0.02, 0.2, 0.4 μg/L, with the relative standard deviations (n=6) ranging from 1.03% to 17.0%. This method was applied for the determination of 27 surface water samples in Jinan section of the Yellow River. The pollutants were mainly PAEs and PAHs, while NBs were not detected, only two kinds of OCPs were detected at some sites. The method is simple, universal, accurate and precise, and has low detection limit. It is suitable for the simultaneous determination of the 46 SVOCs in surface water and groundwater. more...
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- 2021
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44. Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV
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Michel Perron, Xiaofeng Zhao, Richard L. Mackman, Robert Jordan, Daniel Byun, Raju Subramanian, Tomas Cihlar, Kwon Soo Chun, Diane Lye, Christopher A. Palmiotti, Darius Babusis, Hui Hon Chung, Scott Simonovich, Bin Ma, Sarah Wortman, Lijun Zhang, Gary Lee, Julie Chan, Maria M. Toteva, Eisuke Murakami, Kirsten M. Stray, Xianghan Lu, Jared Pitts, Dustin Siegel, John P. Bilello, Kimberly T. Barrett, Bindu Goyal, Cynthia Kim, Arya Vijjapurapu, Venice Du Pont, and Adelle Vandersteen more...
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Chemistry ,viruses ,Metabolite ,Phenotypic screening ,respiratory system ,Prodrug ,Virology ,Virus ,In vitro ,chemistry.chemical_compound ,In vivo ,Drug Discovery ,Molecular Medicine ,African Green Monkey ,Viral load - Abstract
A discovery program targeting respiratory syncytial virus (RSV) identified C-nucleoside 4 (RSV A2 EC50 = 530 nM) as a phenotypic screening lead targeting the RSV RNA-dependent RNA polymerase (RdRp). Prodrug exploration resulted in the discovery of remdesivir (1, GS-5734) that is >30-fold more potent than 4 against RSV in HEp-2 and NHBE cells. Metabolism studies in vitro confirmed the rapid formation of the active triphosphate metabolite, 1-NTP, and in vivo studies in cynomolgus and African Green monkeys demonstrated a >10-fold higher lung tissue concentration of 1-NTP following molar normalized IV dosing of 1 compared to that of 4. A once daily 10 mg/kg IV administration of 1 in an African Green monkey RSV model demonstrated a >2-log10 reduction in the peak lung viral load. These early data following the discovery of 1 supported its potential as a novel treatment for RSV prior to its development for Ebola and approval for COVID-19 treatment. more...
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- 2021
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45. Radiative parameters of high-lying levels in neutral rhodium
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Yaxin Wu, Lijun Zhang, Sébastien Gamrath, Meina Liu, Yidan Geng, Pascal Quinet, Zhenwen Dai, Yongfan Li, and Huiting Ma
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Physics ,010308 nuclear & particles physics ,chemistry.chemical_element ,Astronomy and Astrophysics ,01 natural sciences ,Rhodium ,chemistry ,Space and Planetary Science ,0103 physical sciences ,Radiative transfer ,Atomic physics ,010303 astronomy & astrophysics ,Lying ,Atomic data - Abstract
Radiative lifetimes of 20 high-lying excited levels in neutral rhodium (Rh i) were measured using time-resolved laser-induced fluorescence technique, 17 of which are reported for the first time to our knowledge. These lifetimes were combined with theoretical branching fractions obtained from pseudo-relativistic Hartree–Fock calculations to deduce semi-empirical transition probabilities and oscillator strengths for 63 Rh i spectral lines. more...
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- 2021
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46. Cross-interaction of volatiles from co-pyrolysis of lignin with pig manure and their effects on properties of the resulting biochar
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Chao Li, Lijun Zhang, Yifan Sun, Xun Hu, Shu Zhang, Leilei Xu, Changxu Wang, and Qiaoling Li
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Carbonization ,Soil Science ,chemistry.chemical_element ,Environmental Science (miscellaneous) ,Pollution ,Manure ,Nitrogen ,Biomaterials ,chemistry.chemical_compound ,Chemical engineering ,chemistry ,Biochar ,Lignin ,Heat of combustion ,Char ,Pyrolysis - Abstract
Biomass and pig manure have distinct compositions and the co-pyrolysis of them has gained much attention. However, the influence of volatiles interaction on the properties of the char was still unclear. In this study, lignin was selected as the model component of biomass with pig manure for co-pyrolysis at 600 °C. The results indicate that volatiles from co-pyrolysis promoted re-condensation reaction, resulting in the higher char yield (48.0% in co-pyrolysis versus 31.0% in pyrolysis of single manure) and the formation of more aromatics in bio-oil. The co-pyrolysis also facilitated the dehydrogenation and dehydration reactions, which accounted for the elimination of oxygen and nitrogen contents and thus a higher carbon content (64.7% in the co-pyrolysis versus the averaged value of 46.4% from the pyrolysis of single feedstock), higher crystallinity and thermal stability of the char. The in-situ diffuse reflection infrared Fourier transform spectroscopy (DRIFTS) characterization results demonstrated that the functionalities abundances of char with temperature was influenced by volatiles interaction via accelerating the carbonization reaction. In addition, the high heating value (HHV) of char was obviously improved by cross-interaction of volatiles during co-pyrolysis (24.4 MJ/Kg in co-pyrolysis versus averaged value of 15.1 MJ/Kg from single pyrolysis), implying that the co-pyrolysis enhanced the energy density of the resulting char. more...
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- 2021
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47. Three‐dimensional micro–nanorods‐like structure bimetallic oxide fabricated by dealumination strategy for supercap electrodes
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Dongmei Meng, Yaojian Ren, Lijun Zhang, Zhi Sun, Zhenzhen Zhan, Man Zhang, Peng Cao, Meihua Zhou, Shilin Xu, Jiqiu Qi, Qun Wang, Fuxiang Wei, Lan Ma, and Yanwei Sui
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010302 applied physics ,Supercapacitor ,Materials science ,Oxide ,Condensed Matter Physics ,Electrochemistry ,01 natural sciences ,Capacitance ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Corrosion ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,0103 physical sciences ,Electrode ,Nanorod ,Electrical and Electronic Engineering ,Bimetallic strip - Abstract
Chemical dealloying is an emerging strategy that can be applied to synthesize porous materials. The structure morphologies of the active materials were precisely regulated by designing the various NaOH corrosion solutions. Three-dimensional micro–nanorods-like structure Ni75Cu25O bimetallic oxide with ultra-high electrochemical properties have been obtained, which used Al65Cu15Ni20 precursors through a dealumination strategy. Meanwhile, three-dimensional micro–nanorods-like structure Ni75Cu25O demonstrates an unusual extraordinary specific capacitance (16.96 F cm−2 at 10 mV s−1) and excellent cycling stability (100.8% retention after 5000 cycles at 10 mV s−1). Here, the transition bimetallic oxides by using the dealloying strategy can be applied to develop novel guidances and ideas for the generation of energy storage devices. more...
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- 2021
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48. IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis
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Guangxun Gao, Zhe Wang, Tak W. Mak, Yuanlin Zhao, Yuan Yuan, Risheng Yang, Julie Leca, Jing Ye, Wenjing Zhou, Alan Tseng, Mary E. Saunders, Andrew Wakeham, Yu Gu, Liming Xiao, Feng Zhang, Lijun Zhang, Ying Yang, Wanda Y. Li, Thorsten Berger, Xing Gao, and Jerome Fortin more...
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Ineffective erythropoiesis ,Myeloid ,Erythroblasts ,Immunology ,Mutation, Missense ,Heme ,Biology ,medicine.disease_cause ,Biochemistry ,Glutarates ,Mice ,chemistry.chemical_compound ,Bone Marrow ,hemic and lymphatic diseases ,medicine ,Animals ,Point Mutation ,Preleukemia ,Erythropoiesis ,Ketoglutarate Dehydrogenase Complex ,Myeloid Cells ,Gene Knock-In Techniques ,Myelopoiesis ,Mutation ,Membrane Proteins ,Myeloid leukemia ,Anemia ,Cell Biology ,Hematology ,Hematopoietic Stem Cells ,Thrombocytopenia ,Isocitrate Dehydrogenase ,Recombinant Proteins ,Mice, Inbred C57BL ,Haematopoiesis ,medicine.anatomical_structure ,chemistry ,Splenomegaly ,Cancer research ,Acyl Coenzyme A ,Stem cell ,Reactive Oxygen Species ,Heme Oxygenase-1 - Abstract
Isocitrate dehydrogenase (IDH) mutations are common genetic alterations in myeloid disorders, including acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Epigenetic changes, including abnormal histone and DNA methylation, have been implicated in the pathogenic build-up of hematopoietic progenitors, but it is still unclear whether and how IDH mutations themselves affect hematopoiesis. Here, we show that IDH1-mutant mice develop myeloid dysplasia in that these animals exhibit anemia, ineffective erythropoiesis, and increased immature progenitors and erythroblasts. In erythroid cells of these mice, D-2-hydroxyglutarate, an aberrant metabolite produced by the mutant IDH1 enzyme, inhibits oxoglutarate dehydrogenase activity and diminishes succinyl–coenzyme A (CoA) production. This succinyl-CoA deficiency attenuates heme biosynthesis in IDH1-mutant hematopoietic cells, thus blocking erythroid differentiation at the late erythroblast stage and the erythroid commitment of hematopoietic stem cells, while the exogenous succinyl-CoA or 5-ALA rescues erythropoiesis in IDH1-mutant erythroid cells. Heme deficiency also impairs heme oxygenase-1 expression, which reduces levels of important heme catabolites such as biliverdin and bilirubin. These deficits result in accumulation of excessive reactive oxygen species that induce the cell death of IDH1-mutant erythroid cells. Our results clearly show the essential role of IDH1 in normal erythropoiesis and describe how its mutation leads to myeloid disorders. These data thus have important implications for the devising of new treatments for IDH-mutant tumors. more...
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- 2021
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49. Sycamore fruit seed‐based hard carbon anode material with high cycle stability for sodium‐ion battery
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Zhiqiang Shi, Lei Yan, Yabin Zhao, Lijun Zhang, and Guifang Zhang
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010302 applied physics ,Materials science ,Carbonization ,Diffusion ,chemistry.chemical_element ,Sodium-ion battery ,Condensed Matter Physics ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Anode ,chemistry ,Chemical engineering ,0103 physical sciences ,Crystallite ,Graphite ,Electrical and Electronic Engineering ,Carbon ,Pyrolysis - Abstract
Hard carbon is considered to be one of the most promising anodes for sodium-ion batteries (SIBs), but high cost and poor cycle stability limit the large-scale application for SIBs. Here, a new kind of low-cost sycamore fruit seed hard carbon was prepared by facile pyrolysis at different temperatures as anode for SIBs. With the large interlayer spacing, the reversible specific capacity of sycamore fruit seed carbonized at 1100 °C can reach 323 mAh g−1 at the current density of 0.1 C. When cycled at 0.4 C, the reversible specific capacity is 246.9 mAh g−1, following the capacity retention is 87.85% after 300 cycles. Moreover, we find although the different interlayer spacings (d002 ≥ 0.37 nm) of graphite crystallites of the obtained hard carbon beneficial for the Na+ storage, the smaller d002 limits the diffusion of Na+ inevitably, which affects their cycle stability. This research furnishes a competitive choice about anode materials for the industrialized SIBs. more...
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- 2021
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50. Availability of steam impacts coke properties in steam reforming of acetic acid
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Tao Wei, Guanggang Gao, Xianglin Li, Lijun Zhang, Xun Hu, Zehui Zhang, Shu Zhang, Cuncheng Li, Guozhu Chen, and Zhanming Zhang
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Energy Engineering and Power Technology ,chemistry.chemical_element ,02 engineering and technology ,Carbon nanotube ,010402 general chemistry ,complex mixtures ,01 natural sciences ,Catalysis ,law.invention ,Steam reforming ,Acetic acid ,chemistry.chemical_compound ,law ,Renewable Energy, Sustainability and the Environment ,Chemistry ,technology, industry, and agriculture ,Coke ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,respiratory tract diseases ,0104 chemical sciences ,Fuel Technology ,Chemical engineering ,Particle size ,Absorption (chemistry) ,0210 nano-technology ,Carbon - Abstract
Steam to carbon ratio (S/C) determines the availability of oxygen-containing species during steam reforming, which not only affect the amount of coke formed, but also might impact physicochemical properties of the coke generated. In this study, the effect of S/C on the coke formation in steam reforming of acetic acid was assessed. The results indicated that dissociative absorption of acetic acid generated the intermediates containing both C O and C C groups even at 100 °C. At low S/C, the insufficient ∗OH reacted with carbonaceous intermediates such as CHx to form more carbonyl species, leading to significant coking and lower gas yields. Sufficient ∗OH at high S/C facilitated transformation of the carbonyl-containing species into gases, minimizing coking. The varied amount of coke showed significant effect on the diffraction of metallic nickel phase, the particle size of Ni and the absorption for the Si–O–Si functional groups on spent catalysts. The coke formed at low S/C was more aromatic with high thermal stabilities, while the coke formed at high S/C was more aliphatic with low thermal stabilities. The involvement ∗OH species in coking process determined not only properties but also morphologies of the coke. The coke formed at low S/C showed bamboo-like, dendritic or twisted rope-like structure. While the higher S/C favored the generation of the carbon nanotubes with smooth outer surface. more...
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- 2021
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