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A series of 15-arylisoquinolino[2′,1′:1,2]imidazo[4,5-f][1,10]phenanthrolines was synthesized by a copper(I)-catalyzed reaction of 2-(2-bromophenyl)-1H-imidazo[4,5-f][1,10] phenanthrolines and terminal alkyne in the presence of Cs2CO3. It was proved to be an efficient method for the synthesis of hexacyclic compounds bearing three kinds of heterocycles which were isoquinoline, imidazole and phenanthroline. 15-Arylisoquinolino[2',1':1,2]imidazo[4,5-f][1,10]phenanthrolines were synthesized by a copper(I)-catalyzed reaction of 2-(2-bromophenyl)-1H-imidazo[4,5-f][1,10]phenanthrolines and terminal alkynes in the presence of Cs2CO3. [ABSTRACT FROM AUTHOR]

An unprecedented copper‐catalyzed heteroaromatization/sulfonyl transfer of propargylic alcohols with isocyanide has been developed. 3‐Sulfonyl benzofurans and indoles were produced under Cu(I) catalysis in good to high yields. The developed catalytic methodology provides controlled, modular, and facile access to sulfonyl benzoheterocycle scaffolds. [ABSTRACT FROM AUTHOR]

A double Ullmann coupling reaction successfully takes place between 4,5-diaryl-2-(2-bromophenyl)-1 H -imidazoles and 2-bromophenols in the presence of Cs2 CO3. This procedure is catalyzed by copper(I) iodide and o -phenanthroline and provides an efficient method for the synthesis of dibenzo[ b , f ]imidazo[1,2- d ][1,4]oxazepine derivatives in good yields. [ABSTRACT FROM AUTHOR]

Abstract: CuI accompanyied by Cs2CO3 and TBAB was confirmed to be an efficient catalyst combination to promote an Ullmann coupling reaction. It facilitated 2-bromobenzamides to undergo a coupling reaction for the synthesis of symmetrical biaryldiamides in moderate yields at 120 °C under Pd-free conditions.Graphical Abstract: [ABSTRACT FROM AUTHOR]

A sequential α-arylation of carbonyl reaction and intra-molecular cyclization of 2-(2-bromophenyl)-1 H-benzo[ d]imidazoles with cyclohexane-1,3-diones was described in 1,4-dioxane catalyzed by Cu(I)/ l-proline. It provided an efficient method for the synthesis of benzo[4, 5]imidazo[1,2- f] phenanthridin-4(1 H)-ones with high efficiency in mild conditions. Graphical Abstract: A sequential α-arylation of carbonyl reaction and intra-molecular cyclization of 2-(2-bromophenyl)-1 H-benzo[ d]imidazoles with cyclohexane-1,3-diones was described in 1,4-dioxane catalyzed by Cu(I)/ l-proline. [ABSTRACT FROM AUTHOR]

Isoindolo[1,2- b ]quinazolines was obtained in high yields from a reaction between 2-(2-aminobenzamido)malonate and 2-bromobenzaldehyde catalyzed by CuI under Pd and ligand-free conditions. • It is an α -arylation catalyzed by CuI under ligand-free conditions. • The three new bonds and two new heterocycle are formed. • It is a tandem cyclization reaction to fused tetracyclic isoindolo[1,2- b ]quinazolines. A tandem cyclization reaction of diethyl 2-(2-aminobenzamido)malonates and 2-bromobenzaldehydes was developed for the synthesis of isoindolo[1,2- b ]quinazoline derivatives. The quinazoline was formed first catalyzed by CuI, followed by a noteworthy α -arylation reaction under Pd and ligand-free conditions in the presence of Cs 2 CO 3. [ABSTRACT FROM AUTHOR]