1. Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders
- Author
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Andre Sourander, Dan Sucksdorff, Kim Kronström, Auli Suominen, Roshan Chudal, David Gyllenberg, Elina Jokiranta-Olkoniemi, Nuorisopsykiatria, University of Helsinki, Helsinki University Hospital Area, and HUS Psychiatry
- Subjects
Adult ,Pediatrics ,medicine.medical_specialty ,Autism Spectrum Disorder ,Autism ,CHILDREN ,behavioral disciplines and activities ,3124 Neurology and psychiatry ,03 medical and health sciences ,Epilepsy ,0302 clinical medicine ,Risk Factors ,mental disorders ,Developmental and Educational Psychology ,medicine ,Humans ,0501 psychology and cognitive sciences ,Mortality ,VALIDITY ,Child ,IDEATION ,EPILEPSY ,Cause of death ,Original Paper ,Mortality, Premature ,Public health ,05 social sciences ,PSYCHIATRIC-DISORDERS ,DEATH ,3112 Neurosciences ,medicine.disease ,Comorbidity ,Suicide ,Increased risk ,Harm ,Psychology ,Birth cohort ,Psychiatric disorders ,COMORBIDITY ,Self-Injurious Behavior ,Natural cause ,030217 neurology & neurosurgery ,050104 developmental & child psychology - Abstract
To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987–2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and intentional self-harm. The risk among ASD subjects was elevated only for natural cause of death. The risk for intentional self-harm was increased in the unadjusted analyses, but decreased to non-significant after adjusting for comorbid psychiatric disorders. ASD subjects are at increased risk for premature mortality due to natural causes of death. While ASD subjects die of suicide and present with more self-harm, the association is explained by comorbid psychiatric disorders. Electronic supplementary material The online version of this article (10.1007/s10803-020-04768-x) contains supplementary material, which is available to authorized users.
- Published
- 2021