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A new synthetic protocol to give a variety of symmetric diaryl disulfides from odorless and easily available phenyl dimethylcarbamodithioates was developed. By using phenyl dimethylcarbamodithioates as organosulfur source, the target products were furnished smoothly through simple hydrolysis, giving a series of symmetric diaryl disulfides. The protocol features simple operation, odorless and easily available organosulfur source and high yield. [ABSTRACT FROM AUTHOR]

Under transition‐metal‐free conditions, a series of unsymmetrical disulfides could be quickly and conveniently obtained by NIS (N‐Iodosuccinimide)‐promotion in one pot manner. This method features mild conditions, easy operation, short reaction time and wide substrate scopes. It's noteworthy that the desired products could be obtained in moderate to good yields from inexpensive and easily available starting materials, providing an alternative way to afford various unsymmetrical disulfides. [ABSTRACT FROM AUTHOR]

A highly efficient and convenient method for the water‐involved synthesis of β‐keto dithiocarbamates has been developed. In the presence of minimal water, the desired products were obtained in good to excellent yields by using thiuram disulfide reagents and substituted α‐haloacetophenones as starting materials. This protocol features high atom economy, mild conditions, good functional tolerance and good to excellent yields, showing potential value for the preparation of some biologically and pharmaceutically active compounds. [ABSTRACT FROM AUTHOR]

A convenient and effective method is described to construct C–S/S–S bond starting from O‐alkyl phenylcarbamothioates, giving diverse O‐alkyl S‐phenyl phenylcarbonimidothioates and isothiourea disulfides, respectively. The C–S bond formation products (O‐alkyl S‐phenyl phenylcarbonimidothioates) were synthesized by using Cu2O as catalyst in water (without phase‐transfer catalyst), and the S–S bond formation product (isothiourea disulfides) could be furnished catalyzed by NiBr2 at room temperature. These transformations feature easy control, environmental friendliness, and good to excellent yields, which could be attractive in the selective C–S/S–S bond formation. [ABSTRACT FROM AUTHOR]

An efficient and convenient procedure for the S-arylation of tetraalkylthiuram disulfides by using diaryliodonium salts was explored. In the presence of CuI/KOtBu, two kinds of S-aryl dithiocarbamates could be obtained in good to excellent yields at one time with no clear selectivity. This method has the advantages of efficiency, good atom economy, and broad substrate scope. This protocol allows the facile and convenient preparation of some potentially biologically active compounds. [ABSTRACT FROM AUTHOR]

B The Front Cover b shows an efficient C-S/S-S formation for the chemo-selective synthesis of aryl dithio-carbamates and aryl dialkylcarbamo-(dithioperoxo)thioates. The approach uses inexpensive and readily available diphenyl disulfides and tetramethyl thiuram disulfides as starting materials, a series of aryl dithiocarbamates and aryl dimethylcarbamo(dithioperoxo)thioates could be furnished smoothly in moderate to good yields by modulating the reaction temperature, base, and catalyst. B The Front Cover b shows an efficient C-S/S-S formation for the chemo-selective synthesis of aryl dithio-carbamates and aryl dialkylcarbamo-(dithioperoxo)thioates. [Extracted from the article]

Graphical abstract Highlights • 30 Alkyl Dithiocarbamate derivatives are synthesized in good to excellent yields. • The substrates are cheap and environmentally benign. • The methodology features efficiency, transition-metal-free and easy performance. Abstract An efficient and environmentally benign protocol for the synthesis of S -alkyl dithiocarbamates has been achieved. By reacting tetraalkylthiuram disulfides with alkyl halides, the desired products could be obtained in good to excellent yields. The methodology features efficiency, transition-metal-free, nice yields and easy performance, illustrating it practical synthetic value for the convenient preparation of some potential biologically active molecules. [ABSTRACT FROM AUTHOR]