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Your search keyword '"Kotla, Ravindar"' showing total 1 results
Start Over Author "Kotla, Ravindar" Topic enantioselective catalysis
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1. Enantioselective total synthesis of β-zearalenol from (<italic>s</italic>)-propylene oxide.

Author

Kotla, Ravindar, Murugulla, Adharvana Chari, Ruddarraju, Radhakrishnamraju, Aparna, P., Donthabakthuni, Shobha, and Sridhar, Gattu

Subjects
*PROPYLENE oxide, *ENANTIOSELECTIVE catalysis, *ZEARALENONE, *MACROLIDE antibiotics, *CHEMICAL synthesis, *HYDROXYLATION
Abstract

The total synthesis of 14-membered resorcylic acid macrolide, β-zearalenol, was accomplished starting from commercially available enantiomerically pure propylene oxide and methyl 2,4-dihydroxy-6-methylbenzoate using Grignard reaction, asymmetric dihydroxylation, Yamaguchi macrolactonization, and ring-closing metathesis as key steps. [ABSTRACT FROM AUTHOR]

Published
2018
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