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2. There seems to be a high rate of success in immature teeth that undergo regenerative endodontic treatment, regardless of the cause of pulp necrosis.

4. Systematic review does not provide sufficient evidence that there are important benefits from single-visit revascularization endodontic procedures in immature permanent teeth.

8. There may be no differences in periapical healing between passive ultrasonic irrigation and nonactivated irrigation when undergoing endodontic treatment.

9. Cryotherapy may increase the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis who undergo endodontic treatment.

10. Use of slow-setting calcium silicate–based materials may result in higher failure rates than fast-setting calcium silicate–based materials in patients undergoing endodontic microsurgery.

11. There may be no important differences in the rate of endodontic microsurgery success when using mineral trioxide aggregate or root repair material, but the quality of this evidence is very low.

13. Local infiltration of corticosteroids may decrease pain 48 hours after 1-visit endodontic treatment in patients with irreversible pulpitis.

16. Combination of Gow-Gates and inferior alveolar nerve block may result in a higher rate of successful anesthesia than either technique alone.

17. Acupuncture seems to result in a higher reduction in pain compared with a single 400 milligram dose of ibuprofen in patients with irreversible pulpitis.

18. Direct pulp capping with Biodentine seems to have an acceptable success rate after 1 to 1.5 years.

19. Delayed core or post and crown placement after nonsurgical endodontic treatment resulted in a very small decrease in the survival of the treated teeth in a privately insured population.

21. Root canal retreatment with Thermafil as an obturator seems to have acceptable survival after 5 years.

22. Limitations of a randomized clinical trial's results in uncertainty about relative effects of formocresol versus sodium hypochlorite in primary molars undergoing pulpotomy.

23. High rate of tooth retention and periapical health 10 years after nonsurgical root canal treatment but uncertainty about the factors that may influence these outcomes.

24. COLD IRRIGATION RESULTS IN LESS SEVERE PAIN AFTER ROOT CANAL TREATMENT THAN CONVENTIONAL IRRIGATION IN TEETH WITH SYMPTOMATIC APICAL PERIODONTITIS, BUT THE DIFFERENCE MAY BE NEGLIGIBLE AFTER THE FIRST DAY.

27. USE OF A MICROSCOPE DURING ENDODONTIC TREATMENT SEEMS TO HAVE HELPED LOCATING SECOND MESIOBUCCAL ROOT IN MAXILLARY FIRST MOLARS THAT NEEDED RETREATMENT.

28. PREOPERATIVE PREDNISOLONE AND KETOROLAC MAY RESULT IN A SMALL REDUCTION OF POSTOPERATIVE ENDODONTIC PAIN COMPARED WITH PLACEBO.

29. INSUFFICIENT EVIDENCE TO SUPPORT BENEFITS OF IBUPROFEN SODIUM DIHYDRATE OVER IBUPROFEN ACID TO REDUCE PAIN IN PATIENTS WITH ACUTE ODONTOGENIC PAIN.

30. EVIDENCE ABOUT SUCCESS OF ENDODONTIC TREATMENT OR RETREATMENT VERSUS TOOTH EXTRACTION AND IMPLANT PLACEMENT IS NOT SUFFICIENT FOR MAKING CLINICAL DECISIONS.

31. HIGH PERCENTAGE OF MESIOBUCCAL ROOTS OF MAXILLARY SECOND MOLARS HAVE A COMPLICATED CONFIGURATION AND MORPHOLOGY.

34. HIGH SURVIVAL AND CLINICAL SUCCESS RATES, BUT ALSO HIGH DISCOLORATION RATES, IN IMMATURE NECROTIC TEETH TREATED WITH REGENERATIVE ENDODONTIC PROCEDURES.

35. RECIPROCATING SINGLE-FILE AND MULTIFILE ROTARY INSTRUMENTATION TECHNIQUES LIKELY TO RESULT IN LESS PAIN AFTER ENDODONTIC TREATMENT OF ASYMPTOMATIC NECROTIC MANDIBULAR MOLARS WITH PERIAPICAL LESIONS.

37. AGE, SEX, DIABETES MELLITUS, AND ENDODONTIC TREATMENT AFFECT INCIDENCE OF TOOTH LOSS AFTER PERIODONTAL TREATMENT.

38. MINERAL TRIOXIDE AGGREGATE IS LIKELY TO RESULT IN HIGHER CLINICAL AND RADIOGRAPHIC SUCCESS RATES THAN OTHER ALTERNATIVES IN IMMATURE NECROTIC TEETH.

39. 2% MEPIVACAINE SEEMS TO DO BETTER THAN 2% LIDOCAINE IN ACHIEVING SUCCESSFUL ANESTHESIA IN POSTERIOR TEETH WITH IRREVERSIBLE PULPITIS.

40. NO EVIDENCE OF DIFFERENCES IN SURVIVAL AND FAILURE RATES OF ENDODONTICALLY TREATED TEETH RESTORED WITH COMPOSITE RESIN OR METAL CROWNS.

41. NO EVIDENCE FROM RANDOMIZED TRIALS TO PREFER ANY DIRECT PULP CAPPING MATERIAL OVER ANOTHER.

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