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Objective: To evaluate the clinical efficacy of ROI-C in ACDF and to explore its advantages and disadvantages. Methods: From 2017.06 to 2018.06, 84 cases of patients with Cervical spondylotic myelopathy included in this study, and all of the patients have received Anterior Cervical Discectomy and Fusion were divided into two groups according to different operation ways. 48 patients underwent surgery using ROI-C (experimental group), while 36 patients underwent surgery with Anterior Cervical Locking Plate System (control group). The operation time, bleeding and hospital stay were compared between the two groups, and using VAS score and JOA score to evaluate the clinical efficacy, and make a record of surgical complications, and SPSS 19.0 is used for statistical analysis. Results: There was no significant difference in VAS, JOA and Macnab score between the two groups in 3 days, 6 months and 12 months after operation (P > 0.05) while it has a statistically significant difference compared with preoperative (P < 0.01). Surgeries in both of the two groups were successfully completed, and there were no complications such as nerve injury, hematoma and infection (P > 0.05). There was significant difference in the operation time, operation blood lose and hospital stay time between the two groups. Conclusion: Comparing the traditional system of anterior cervical locking plate in ACDF, using the ROI-C in the treatment of cervical spondylosis has a definite clinical curative effect, however, which can short operation time and the reducing postoperative swallowing discomfort and short hospital stay time, which is worth to promotion and application. [ABSTRACT FROM AUTHOR]

Objective: To investigate the clinical effect and safety of different blood purifications on the patients with multiple organ dysfunction syndrome caused by poisoning. Methods: From September 2015 to September 2018, 41 patients diagnosed as multiple organ dysfunction syndrome caused by poisoning were retrospectively analyzed. All the patients were divided into two groups by different blood purifications: experimental group (sequential blood purification group) or control group (single blood purification group). The clinical outcomes were evaluated by general situation (hospitalization time and hospitalization costs) and main blood indicators, APACHE Ⅱ score and survival rates after treatment. Results: Compared with the control group, the ALT, AST, CK-MB, LDH, Cr, Bun levels and APACHE Ⅱ score of treatment group were significantly lower than those of the control group after 5 days of treatment (P< 0.05). The hospitalization cost of treatment group was higher than taht of the control group(P<0.05), while the length of hospital stay and the mortality of treatment group showed no significant difference between two groups (P>0.05). Conclusion: Compared with the single mode of blood purification, sequential therapy can significantly improve the hepatic function, reduce the APACHE II score for poisoning MODS, though it is more expensive, it won't increase the hospitalization time. [ABSTRACT FROM AUTHOR]

Objective: To explore the clinical effect and safety of percutaneous endoscopic lumbar discectomy(PELD) using Proxomed Tergumed in the treatment of patients with lumbar disc herniation. Methods: From June 2016 to June 2017, 63 cases of patients who were diagnosed as lumbar disc herniation and operated in our hospital were retrospectively analyzed. All the patients were divided into the experimental group(Proxomed Tergumed group) and the control group(tradition group). The clinical outcomes were evaluated by visual analogue scale(VAS) and Oswestry Disability Index(ODI) score, muscular power and complications at 1 week, 3 months and 6 months after operation. Results: The VAS score and ODI score of both groups were significantly lower than those preoperation. There was no obvious difference in the VAS and ODI score at the the first week after operation between two groups(P>0.05), while the VAS and ODI core of experimental group at 3 and 6 months after operation were significantly lower than those of the control group(P<0.05). Compared with the preoperative muscular power, there was statistical differences at 6 months after operation(P<0.05). There was no obvious difference in each muscle strength at 6 months after operation in the experimental group(P>0.05), which were significantly lower in control group(P<0.05). Conclusions: As a part of early rehabilitation training for patients who have undergone treated with percutaneous endoscopic lumbar discectomy, Proxomed Tergumed can effectively reduce the possibility of postoperative complications, relief postoperative pain and reduce the time of postoperative recovery, which has its obvious advantage comparing with traditional postoperative rehabilitation training. [ABSTRACT FROM AUTHOR]