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Resumen Introduccion La enfermedad inflamatoria intestinal (EII) es un factor de riesgo independiente para presentar fenomenos tromboembolicos (FTE). Evaluamos la prevalencia y los posibles factores de riesgo asociados a presentar FTE en pacientes con EII en nuestro centro. Material y metodos Se recogieron los datos de forma retrospectiva desde enero de 1995 hasta diciembre de 2011, obteniendo un total de 23 pacientes. Un 61% habia sido diagnosticado de enfermedad de Crohn (EC) y un 39% de colitis ulcerosa (CU) segun los criterios habituales. Resultados Utilizando la clasificacion de Montreal, el 58% de los pacientes con EC tenia un patron inflamatorio (B1), el 25% un patron estenosante (B2) y el 17% un patron fistulizante (B3). Respecto a la localizacion, la mitad de los pacientes tenian afectacion ileocolica (L3), un tercio afectacion colica (L2) y el resto afectacion ileal (L1). Entre los pacientes con CU segun la clasificacion de Montreal, el 78% sufria una colitis extensa (E3), el 11% tenia afectacion de colon izquierdo (E2) y el 11% proctocolitis (E1). Durante el episodio, casi la mitad de los pacientes con CU tenian actividad inflamatoria severa (S3: 44%), un 33% actividad leve-moderada (S1: 22%; S2: 11%) y solo el 22% se encontraba en periodo quiescente (S0). De forma global, en el momento del FTE, el 48% de los pacientes tenia actividad leve-moderada y el 22% actividad severa. Asimismo, un 44% se encontraban hospitalizados en el momento de sufrir el episodio. En la CU se encontro un aumento de la prevalencia entre aquellos que se encontraban ingresados (66%). Ningun paciente tenia antecedentes familiares, 2 de ellos (9%) presentaban trombofilia asociada y un 26% eran fumadores activos. No hubo ningun fenomeno durante la gestacion. Solo una paciente tomaba anticonceptivos en el momento de sufrir el episodio. El FTE que se produjo con mayor frecuencia fueron las trombosis venosas profundas (TVP) de miembros inferiores (55%) seguidas de la tromboembolia pulmonar (TEP) (25%). Conclusiones Los FTE en la EII son relativamente frecuentes, con un importante impacto en la morbimortalidad de estos pacientes. En nuestra serie supusieron factores de riesgo para presentarlos la afectacion intestinal mas extensa (en cualquiera de los grupos) y la actividad inflamatoria severa. No se encontro una asociacion significativa entre los factores de riesgo clasicos como el uso de anticonceptivos, el embarazo, las enfermedades de la coagulacion o el habito tabaquico y el riesgo de presentar fenomenos tromboembolicos.

Inflammatory bowel disease (IBD) is an independent risk factor for thromboembolic phenomena (TEP). We evaluated the prevalence and the possible risk factors associated with developing TEP in patients with IBD in our center.Data were retrospectively collected from January 1995 to December 2011 from 23 patients. A total of 61% were diagnosed with Crohn's disease (CD) and 39% with ulcerative colitis (UC) according to routine criteria.When the Montreal classification was used, 58% of the patients with CD had an inflammatory pattern (B1), 25% a stenosing pattern (B2) and 17% a fistulizing pattern (B3). Half the patients had ileocolic involvement (L3), one-third had colonic involvement (L2) and the remainder had ileal involvement (L1). Among patients with UC according to the Montreal classification, 78% had extensive colitis (E3), 11% had left colonic involvement (E2) and 11% had proctocolitis (E1). During the event, almost half the patients with UC had severe inflammatory activity (S3; 44%), 33% had mild-moderate activity (S1: 22%, S2: 11%) and only 22% were in remission (S0). Overall, at the time of the TEP, 48% of the patients had mild-moderate activity and 22% had severe activity. Likewise, 44% were hospitalized at the time of the event. In UC, an increase in the prevalence of TEP was found in admitted patients (66%). None of the patients had a family history of TEP, two patients (9%) had associated thrombophilia and 26% were active smokers. There were no TEP during pregnancy. Only one patient was taking contraceptive pills when the event occurred. The most frequent forms of TEP were deep vein thrombosis of the legs (55%) followed by pulmonary thromboembolism (25%).TEP are relatively frequent in patients with IBD, with a strong impact on morbidity and mortality. In our series, risk factors for these events were more extensive involvement (any of the groups) and severe inflammatory activity. No significant association between classical risk factors such as the use of contraceptives, pregnancy, coagulation disorders or smoking and the risk of TEP were found.