1. Glucose oxidase@zinc-doped zeolitic imidazolate framework-67 as an effective cascade catalyst for one-step chemiluminescence sensing of glucose.
- Author
-
Xu X, Ma Y, Ding S, and Li Y
- Subjects
- Catalysis, Humans, Luminescence, Glucose chemistry, Glucose Oxidase chemistry, Imidazoles chemistry, Zeolites chemistry
- Abstract
A chemiluminescence (CL) sensor was constructed for the one-step determination of glucose. Glucose oxidase (GOx) was successfully encapsulated into Zn-doped zeolitic imidazolate framework-67 (Zn-ZIF-67) via a simple one-pot strategy. The as-prepared GOx@Zn-ZIF-67 nanocomposite can trigger cascade reactions of glucose oxidation to generate H
2 O2 and H2 O2 -mediated luminol reaction to give an intense CL emission. The sensor responds linearly to glucose in the 20.0-400.0 μmol·L-1 range with a limit of detection (LOD) of 4.7 μmol·L-1 . Eleven replicated measurements of 200.0 μmol·L-1 glucose solution gives a relative standard deviation (RSD) of 1.7%. The sensor exhibits good selectivity and stability and was successfully applied to the determination of glucose in real human serum samples. Schematic representation of one-step determination of serum glucose with GOx@Zn-ZIF-67 nanocomposite triggering cascade reactions between luminol and glucose., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)- Published
- 2021
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