1. Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy.
- Author
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Lee HJ, Lee CH, Kim JW, Park YS, Lee J, and Kim KA
- Subjects
- Adult, Aged, Antineoplastic Agents therapeutic use, Biliary Tract pathology, Breast Neoplasms diagnosis, Breast Neoplasms drug therapy, Female, Gadolinium, Humans, Liver pathology, Liver Neoplasms diagnostic imaging, Liver Neoplasms drug therapy, Middle Aged, Prognosis, Reproducibility of Results, Retrospective Studies, Treatment Outcome, Biliary Tract diagnostic imaging, Breast Neoplasms pathology, Contrast Media, Gadolinium DTPA, Liver diagnostic imaging, Liver Neoplasms secondary, Magnetic Resonance Imaging methods
- Abstract
Objectives: To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer., Methods: 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a "target" or "non-target" appearance. The relationship of appearance or SI ratio with tumor response was analyzed., Results: A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (22.2%)], and it was associated with a better response [p=0.048]., Conclusion: HBP analysis may be useful to predict the response to chemotherapy and survival., (Copyright © 2017 Elsevier Inc. All rights reserved.)
- Published
- 2017
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