1. AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease: Expert Review.
- Author
-
Younossi ZM, Corey KE, and Lim JK
- Subjects
- Behavior Therapy methods, Behavior Therapy standards, Evidence-Based Medicine methods, Evidence-Based Medicine standards, Exercise Therapy methods, Exercise Therapy standards, Gastroenterology methods, Healthy Lifestyle, Humans, Liver pathology, Liver Cirrhosis pathology, Non-alcoholic Fatty Liver Disease etiology, Non-alcoholic Fatty Liver Disease pathology, Obesity complications, Quality of Life, Societies, Medical standards, United States, Weight Loss, Gastroenterology standards, Liver Cirrhosis prevention & control, Non-alcoholic Fatty Liver Disease therapy, Obesity therapy, Risk Reduction Behavior
- Abstract
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease, with global public health impact affecting more than 25% of the global population. NAFLD is associated with significant morbidity and mortality from cirrhosis, hepatocellular carcinoma, solid organ malignancies, diabetes mellitus, cardiovascular disease, and obstructive sleep apnea, resulting in significant health care resource use and decreased health-related quality of life. NAFLD cirrhosis is a leading indication for liver transplantation in the United States. Lifestyle modification to achieve weight loss remains a first-line intervention in patients with NAFLD. We summarize evidence-based interventions for lifestyle modification in the treatment of NAFLD and provided best practice advice statements to address key issues in clinical management., (Copyright © 2021 AGA Institute. Published by Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
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