1. Demographic and clinical patterns of severe asthma in the Middle East
- Author
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Ali Saeed Wahla, Bassam Mahboub, Khaled Saleh, Mateen Uzbeck, Mohamed Abuzakouk, Govinda Saicharan Bodi, Zaid Zoumot, Fulvio Salvo, Omar Ghorab, Jeffrey T. Chapman, Deepa Grandon, Yaser Abu El Sameed, Mohsen Nasir, Ashraf Alzaabi, Irfan Shafiq, and Rajaie Namas
- Subjects
Pulmonary and Respiratory Medicine ,Pediatrics ,medicine.medical_specialty ,Demographics ,Severe asthma ,airflow obstruction ,Tertiary care ,Asthma care ,severe asthma epidemiology ,Diseases of the respiratory system ,immune system diseases ,Female preponderance ,Epidemiology ,Medicine ,Diseases of the circulatory (Cardiovascular) system ,Asthma ,RC705-779 ,business.industry ,th1/th2 ,asthma epidemiology ,asthma ,medicine.disease ,respiratory tract diseases ,RC666-701 ,Original Article ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,allergic asthma ,Asthma Control Test - Abstract
BACKGROUND: Severe asthma is a major burden on health-economic resources; hence, knowing the epidemiology of these patients is important in planning and provision of asthma care. In addition, identifying and managing the comorbidities helps improve symptoms and reduce associated morbidity and mortality. OBJECTIVES: Epidemiology of difficult asthma has not been well studied in the Middle East, so in this study, we present the demographic and clinical characteristics of severe asthma in the United Arab Emirates (UAE). METHODS: We retrospectively reviewed the notes of severe asthma patients attending three tertiary care hospitals between May 2015 and December 2019. Data on baseline demographics, asthma characteristics, treatment, and comorbidities were collected. RESULTS: We reviewed the notes of 458 patients (271 females and 187 males) that fulfilled the 2019 Global Initiative for Asthma guidelines for the diagnosis of severe asthma. The mean age was 47.7 (standard deviation 17.2) years. Males had significantly higher asthma control test scores (17.9 vs. 16, P = 0.01) and mean blood eosinophils (0.401 vs. 0.294, P
- Published
- 2021