1. Critical peritonitis secondary to gastrointestinal mucormycosis in a peritoneal dialysis patient: a case report
- Author
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Kiyoshi Kajiyama, Sho Sasaki, Ryosuke Minagawa, Yusuke Nakamata, Takashi Matono, Takafumi Nakashima, Soken Hattori, Makoto Hirakawa, Kazuhiro Okamura, Takuro Kometani, and Tomoya Hamashoji
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Peritonitis ,Case Report ,Peritoneal dialysis ,Peritoneal Dialysis, Continuous Ambulatory ,Gastrointestinal perforation ,medicine.artery ,Medicine ,Ascending colon ,Humans ,Mucormycosis ,Aged ,business.industry ,Continuous ambulatory peritoneal dialysis ,Ileocolic artery ,General Medicine ,medicine.disease ,Surgery ,Catheter ,Mycoses ,business ,Peritoneal Dialysis - Abstract
Immunodeficient patients are susceptible to systemic fungal infections; however, these rarely cause secondary peritonitis. A 66-year-old man with multiple myeloma and diabetes mellitus on continuous ambulatory peritoneal dialysis (CAPD) presented with cloudy ascitic fluid. He had been treated with corticosteroids for 1 month for Tolosa–Hunt syndrome. We diagnosed peritoneal dialysis-related peritonitis caused by Enterococcus avium, removed the CAPD catheter, and initiated intravenous ampicillin. Computed tomography (CT) revealed an intramural gastric mass and a thinning ascending colon wall. Four days later, follow-up contrast-enhanced CT showed penetration of the ascending colon and rupture of the ileocolic artery. Emergency open surgery revealed hemorrhagic infarction with mucormycosis. We initiated intravenous liposomal amphotericin B 20 days after admission; however, he died 55 days later. Anatomical abnormalities, such as gastrointestinal perforation, should be considered for peritonitis in immunodeficient patients. Gastrointestinal mucormycosis is rare but fatal, resulting from a delay in diagnosis and consequent gastrointestinal perforation. For an early diagnosis and a favorable clinical outcome, it is important to consider the risk factors for mucormycosis, including corticosteroid use, diabetes, end-stage kidney diseases.
- Published
- 2021