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Your search keyword '"Tingxuan Huang"' showing total 7 results
Start Over Author "Tingxuan Huang" Topic medicine.medical_specialty
7 results on '"Tingxuan Huang"'

2. Dupilumab in patients with uncontrolled asthma: type 2 biomarkers might be predictors of therapeutic efficacy

Author

Tingxuan Huang, Chuntao Liu, Zhuman Du, Bicui Liu, and Dan Yang

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Treatment outcome, MEDLINE, Antibodies, Monoclonal, Humanized, Nitric Oxide, Leukocyte Count, 03 medical and health sciences, Th2 Cells, 0302 clinical medicine, immune system diseases, Internal medicine, medicine, Humans, Immunology and Allergy, In patient, Anti-Asthmatic Agents, 030212 general & internal medicine, Randomized Controlled Trials as Topic, Asthma, Chemokine CCL26, business.industry, medicine.disease, Dupilumab, respiratory tract diseases, Uncontrolled asthma, Eosinophils, Treatment Outcome, 030228 respiratory system, Exhalation, Pediatrics, Perinatology and Child Health, Monoclonal, Chemokine CCL17, business, Biomarkers
Abstract

To the Editor,We read with great interest the recent study by Zayed et al. reporting dupilumab safety and efficacy in uncontrolled asthma [1]. They reported that the addition of dupilumab reduced r...

Published
2019

3. Can tiotropium add-on therapy safely improve clinical outcomes in children and adolescents with persistent asthma?

Author

Chuntao Liu, Xinning Guo, Dan Yang, Qian Peng, and Tingxuan Huang

Subjects
Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Adolescent, business.industry, Immunology, MEDLINE, Asthma, Bronchodilator Agents, Add on therapy, Pharmacotherapy, Text mining, Adrenal Cortex Hormones, Meta-analysis, medicine, Humans, Immunology and Allergy, Drug Therapy, Combination, Female, Tiotropium Bromide, Child, Intensive care medicine, Persistent asthma, Combination method, business
Published
2020

4. To the editor: Does Continuous Positive Airway Pressure (CPAP) treatment of obstructive sleep apnoea (OSA) improve asthma-related clinical outcomes in patients with co-existing conditions?

Author

Chuntao Liu, Bicui Liu, Dan Yang, and Tingxuan Huang

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure, business.industry, medicine.medical_treatment, medicine.disease, Sleep in non-human animals, Asthma, Emergency medicine, Medicine, Cpap treatment, Humans, In patient, Continuous positive airway pressure, business
Published
2018

5. Asthma-associated bronchiectasis: More attention needed!

Author

Chuntao Liu, Bicui Liu, Ling Yang, Dan Yang, and Tingxuan Huang

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Bronchiectasis, Exacerbation, business.industry, medicine.disease, Asthma, medicine, Humans, Intensive care medicine, business, Finland, Lung function
Published
2020

6. Etiology of 1805 adult patients with bronchiectasis in western China

Author

Dan Yang, Jian Luo, Bin-Miao Liang, Tingxuan Huang, Dan Wang, Xiaohu Wang, Bicui Liu, and Chun-Tao Liu

Subjects
Pediatrics, medicine.medical_specialty, Bronchiectasis, Adult patients, business.industry, Etiology, Medicine, business, China, medicine.disease
Published
2018

7. Efficacy and safety of antagonists for chemoattractant receptor-homologous molecule expressed on Th2 cells in adult patients with asthma: a meta-analysis and systematic review

Author

Dan Wang, Jing Yang, Bin-Miao Liang, Ling Yang, Chuntao Liu, Jian Luo, Xiaohu Wang, Dan Yang, Tingxuan Huang, and Bicui Liu

Subjects
0301 basic medicine, medicine.medical_specialty, Receptors, Prostaglandin, Review, Placebo, 03 medical and health sciences, 0302 clinical medicine, Th2 Cells, Internal medicine, medicine, Humans, Anti-Asthmatic Agents, Receptors, Immunologic, Adverse effect, Asthma, Randomized Controlled Trials as Topic, lcsh:RC705-779, business.industry, Absolute risk reduction, lcsh:Diseases of the respiratory system, medicine.disease, Confidence interval, Lung function, Clinical trial, Meta-analysis, 030104 developmental biology, Treatment Outcome, 030228 respiratory system, Relative risk, Adverse events, Systematic review, business, CRTH2 antagonist
Abstract

Background Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) antagonists are novel agents for asthma but with controversial efficacies in clinical trials. Therefore, we conducted a meta-analysis to determine the roles of CRTH2 antagonists in asthma. Methods We searched in major databases for RCTs comparing CRTH2 antagonists with placebo in asthma. Fixed- or random-effects model was performed to calculate mean differences (MD), risk ratio (RR) or risk difference (RD) and 95% confidence interval (CI). Results A total of 14 trails with 4671 participants were included in our final analysis. Instead of add-on treatment of CRTH2 antagonists to corticosteroids, CRTH2 antagonist monotherapy significantly improved pre-bronchodilator FEV1 (MD = 0.09, 95% CI 0.04 to 0.15, P = 0.0005), FEV1% predicted (MD = 3.65, 95% CI 1.15 to 6.14, P = 0.004), and AQLQ (MD = 0.25, 95% CI 0.09 to 0.41, P = 0.002), and reduced asthma exacerbations (RR = 0.45, 95% CI 0.23 to 0.85, P = 0.01). Rescue use of SABA was significantly decreased in both CRTH2 antagonist monotherapy (MD = − 0.04, 95% CI -0.05 to − 0.03, P

Published
2018

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