1. P.267 Association of chronotype and variation in the CLOCK gene in a large general European population sample.
- Author
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Győrik, D., Sütöri, S., Eszlari, N., Baksa, D., Bagdy, G., Juhasz, G., and Gonda, X.
- Subjects
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CLOCK genes , *MORNINGNESS-Eveningness Questionnaire , *MOLECULAR clock , *BIPOLAR disorder , *AFFECTIVE disorders , *MENTAL depression , *SCHOLARSHIPS ,BEETLE anatomy - Abstract
B Introduction: b Mental health disorders have a huge impact on the well-being of the population, with affective disorders showing the highest prevalence and depression predicted to become the illness associated with the highest disease burden in the near future. B Aim: b The aim of the present study is to reveal associations between variation of the CLOCK gene, circadian phenotypes ascertained by the Morningness-Eveningness Questionnaire and lifetime depression in a large European general population sample. B Conclusion: b Investigating the genetic background of chronotype and its links to mood disorders contributes to elucidating biological pathways behind MDD and BD as well as alleviates a more precise estimation of the risk of developing depression. [Extracted from the article]
- Published
- 2020
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