1. Maternal vitamin D levels and the risk of perinatal death.
- Author
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McGuigan, India, Flatley, Christopher, and Kumar, Sailesh
- Subjects
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VITAMIN D , *STEROID hormones , *PERINATAL death , *INFANT mortality , *POSTMORTEM birth , *GESTATIONAL age , *VITAMIN D deficiency , *CROSS-sectional method , *RETROSPECTIVE studies , *CASE-control method - Abstract
Objective: To determine the association between maternal vitamin D levels and perinatal death.Methods: A retrospective cross-sectional study of all non-anomalous, singleton births (≥24 weeks) with perinatal death compared to a matched control group. Only pregnancies with a recorded vitamin D level at booking (8-19 weeks gestation) were included for analysis. Maternal vitamin D levels were categorized into normal, deficient and insufficient cohorts and variables compared between the three groups.Results: There were 31 perinatal deaths which were compared to 111 controls. Median vitamin D levels were lower in the perinatal death cohort compared to the control group (55 nmol/L versus 64 nmol/L, p = 0.43). There was no significant increase in deaths between the normal and deficient (p = 0.33) or insufficient (p = 0.09) groups.Conclusions: Low maternal vitamin D levels at booking were not associated with an increased risk of perinatal demise. [ABSTRACT FROM AUTHOR]- Published
- 2017
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