Search

Your search keyword '"Patel, Gayatri"' showing total 15 results
Start Over Author "Patel, Gayatri" Topic pharmaceuticals and cosmetics industries
15 results on '"Patel, Gayatri"'

1. Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Author

Patel, Gayatri and Patel, Divyangi

Subjects
Medical research, Medicine, Experimental, Patient compliance, Ion exchange resins, Doxylamine, Cefpodoxime, Business, Pharmaceuticals and cosmetics industries
Abstract

Cefpodoxime proxetil (CFPD PRXL) is a third-generation cephalosporin antibiotic with broad-spectrum activity. However, its bitter taste often leads to poor patient compliance. This study aimed to develop a taste-masked drug [...]

Published
2024

2. Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Author

Patel, Gayatri and Patel, Divyangi

Subjects
Urinary tract infections -- Health aspects, Patient compliance -- Health aspects, Ion exchange resins -- Health aspects, Bacterial infections -- Health aspects, Doxylamine -- Health aspects, Cefpodoxime -- Health aspects, Business, Pharmaceuticals and cosmetics industries
Abstract

Cefpodoxime proxetil (CFPD PRXL) is a third-generation cephalosporin antibiotic with broad-spectrum activity commonly prescribed in both solid and liquid forms to treat various bacterial infections, including upper respiratory infections, ear [...]

Published
2024

3. Formulation of Modified Liquid-Solid Compact for Dissolution Enhancement of Raloxifene Hydrochloride

Author

Patel, Gayatri, Pandya, Dharmang, Gandhi, Pushti, and Parikh, Rajesh

Subjects
Osteoporosis -- Research, Raloxifene -- Research, Postmenopausal women -- Research, Povidone -- Research, Estrogen -- Antagonists, Business, Pharmaceuticals and cosmetics industries
Abstract

Raloxifene hydrochloride (RLX), used in postmenopausal osteoporosis, is a class-ll drug as per Biopharmaceutics Classification System. The purpose of this research was to formulate modified liquisolid compacts (MLSC) of RLX [...]

Published
2021

4. Formulation of Modified Liquid-Solid Compact for Dissolution Enhancement of Raloxifene Hydrochloride: Raloxifene hydrochloride (RLX), used in postmenopausal osteoporosis, is a class-II drug as per Biopharmaceutics Classification System. The purpose of this research was to formulate modified liquisolid compacts (MLSC) of RLX for improved dissolution in immediate-release tablet formulations. Preliminary trials on selection of excipients were performed. Fourier transform infrared spectra illustrated no interaction between drug and MLSC powder. The X-ray diffraction studies demonstrated the transformation of the crystalline nature of drug into partial amorphous state in MLSC. After all experimental results on selection of excipients were analyzed, the final tablet formulation was derived and manufactured. The results of an in-vitro drug release study from the selected batch illustrated a remarkable improvement in the dissolution rate as compared to reference product

Author

Patel, Gayatri, Pandya, Dharmang, Gandhi, Pushti, and Parikh, Rajesh

Subjects
Dissolution (Chemistry) -- Analysis, Raloxifene -- Product development -- Analysis, X-rays -- Diffraction, Osteoporosis -- Care and treatment, Postmenopausal women -- Care and treatment, Pharmaceutical industry -- Product development, Business, Pharmaceuticals and cosmetics industries
Abstract

More than 40% new chemical entities (NCE) developed in pharmaceutical industries are insoluble in biological fluid, thus making solubility a major challenge for any formulation scientist. Good dissolution in biological [...]

Published
2021

5. Using Quality by Design to Develop Fixed-Dose Combination Tablets

Author

Kotadiya, Rajendra, Jasani, Krunal, and Patel, Gayatri

Subjects
Povidone -- Dosage and administration, Drug therapy, Combination, Business, Pharmaceuticals and cosmetics industries
Abstract

In the present investigation, the fixed-dose combination (FDC) tablet of Atorvastatin calcium and Ezetimibe was prepared by a quality-by-design approach using [2.sup.3] factorial design. Precompression and post-compression parameters were determined [...]

Published
2021

6. Using Quality by Design to Develop Fixed-Dose Combination Tablets

Author

Kotadiya, Rajendra, Jasani, Krunal, and Patel, Gayatri

Subjects
Drug therapy, Combination -- Methods -- Analysis, Business, Pharmaceuticals and cosmetics industries
Abstract

In the present investigation, the fixed-dose combination (FDC) tablet of Atorvastatin calcium and Ezetimibe was prepared by a quality-by-design approach using [2.sup.3] factorial design. Precompression and post-compression parameters were determined [...]

Published
2021

7. Development of Taste-Masked Oral Reconstitutable Suspension of Cetrizine Dihydrochloride

Author

Patel, Gayatri C.

Subjects
Pharmaceutical Press, Patient compliance, Ion exchange resins, Business, Pharmaceuticals and cosmetics industries
Abstract

Cetirizine dihydrochloride (CTZ) is a second-generation piperazine derivative, a potent H1 selective antihistaminic agent. Its extreme bitter taste results in poor patient compliance. The aim of this study was to [...]

Published
2020

8. Development of Taste-Masked Oral Reconstitutable Suspension of Cetirizine Dihydrochloride

Author

Patel, Gayatri C.

Subjects
Drugs -- Controlled release, Ion exchange resins -- Usage, Cetirizine -- Production processes -- Properties, Controlled release preparations -- Analysis, Business, Pharmaceuticals and cosmetics industries
Abstract

Cetirizine dihydrochloride (CTZ) is a secondgeneration piperazine derivative, a potent H1 selective antihistaminic agent. Its extreme bitter taste results in poor patient compliance. The aim of this study was to [...]

Published
2020

9. Optimizing Compression Coating for Pulsatile Release Tablets: Research examined the effects of varying excipient and polymer weight in coatings designed to optimize release of diclofenac sodium, with the goal of releasing it at night to improve the treatment of rheumatoid arthritis

Author

Patel, Gayatri C.

Subjects
Diclofenac -- Research, Rheumatoid factor -- Research -- Analysis, Arthritis -- Research -- Drug therapy, Polymers -- Analysis -- Research, Coatings -- Research -- Analysis, Business, Pharmaceuticals and cosmetics industries
Abstract

As the fields of chronopharmaceutics and chronophar-macology (1) reveal more about the importance of circadian rhythms with respect to human physiology, disease state, and drug action, time-controlled pulsatile-release tablets are [...]

Published
2019

10. Optimizing Compression Coating for Pulsatile Release Tablets: Research examined the effects of varying excipient and polymer weight in coatings designed to optimize the release of diclofenac sodium. The goal was to release it at night to improve the treatment of rheumatoid arthritis

Author

Patel, Gayatri C.

Subjects
Polymers -- Influence, Excipients -- Influence, Rheumatoid arthritis -- Drug therapy, Enteric-coated tablets -- Materials, Business, Pharmaceuticals and cosmetics industries
Abstract

The concept of pulsatile release, in which active ingredient is fully and quickly released after a predetermined lag time, is gaining popularity as a drug-delivery approach. Pulsatile release offers a [...]

Published
2019

11. Optimizing Manufacturing Based on the Storage Stability of Pegylated Products: Research into peginterferon alfa-2b's degradation pathways suggest that drug substance be immediately and continuously converted to drug product when the material is in liquid form

Author

Patel, Chintan, Bandyopadhyay, Sanjay, and Patel, Gayatri

Subjects
Drug stability -- Testing, Peginterferon alfa-2b -- Chemical properties -- Testing -- Storage, Business, Pharmaceuticals and cosmetics industries
Abstract

Depending on the polyethylene glycol reagent and chemistry used to manufacture them, pegylated products may exhibit different degradation patterns under different storage conditions. To ensure product quality, it is essential [...]

Published
2019

12. Optimizing Manufacturing Based on the Storage Stability of Pegylated Products: Research into peginterferon alfa-2b's degradation pathways suggest that drug substance be immediately and continuously converted to drug product when the material is in liquid form

Author

Patel, Chintan, Bandyopadhyay, Sanjay, and Patel, Gayatri

Subjects
Backup software, Polyethylene glycol, Viral antigens, Polyols, Pegademase, Interferon, Production management, Glycols (Class of compounds), Backup software, Business, Pharmaceuticals and cosmetics industries, Peg-Intron (Medication), Oncaspar (Medication)
Abstract

Depending on the polyethylene glycol reagent and chemistry used to manufacture them, pegylated products may exhibit different degradation patterns under different storage conditions. To ensure product quality, it is essential [...]

Published
2019

13. Degradation Pathways: A Case Study with Pegylated L-Asparaginase

Author

Patel, Chintan, Bandyopadhyay, Sanjay, and Patel, Gayatri

Subjects
Merck & Company Inc., Asparaginase -- Case studies, Backup software -- Case studies, Pharmaceutical industry -- Case studies, Technology, Production management, Backup software, Business, Pharmaceuticals and cosmetics industries, Oncaspar (Medication)
Abstract

Pegylation is a well-known technology used to increase residence time of L-asparaginase in blood circulation and to reduce hypersensitivity reactions; however, it is important to address manufacturing problems associated with [...]

Published
2019

14. Degradation Pathways: A Case Study with Pegylated L-Asparaginase

Author

Patel, Chintan, Bandyopadhyay, Sanjay, and Patel, Gayatri

Subjects
Backup software -- Case studies, Asparaginase -- Case studies, Technology, Production management, Backup software, Business, Pharmaceuticals and cosmetics industries
Abstract

Pegylation is a well-known technology used to increase residence time of L-asparaginase in blood circulation and to reduce hypersensitivity reactions; however, it is important to address manufacturing problems associated with [...]

Published
2019

15. Developing a modified Pulsincap system

Author

Patel, Gayatri C. and Patel, Madhabhai M.

Subjects
Drugs -- Vehicles, Diclofenac -- Dosage and administration, Pharmacokinetics -- Research, Drug delivery systems -- Usage -- Methods, Rheumatoid arthritis -- Drug therapy -- Research, Business, Pharmaceuticals and cosmetics industries, Drug therapy, Usage, Research, Methods, Dosage and administration
Abstract

Traditional oral dosage forms of diclofenac sodium (DS) used for the treatment of rheumatoid arthritis (RA) do not always offer pain protection that fully coincides with the rhythm of the [...]

Published
2009

Catalog

Books, media, physical & digital resources
See catalog results