1. Characteristics and applications of alginate lyases: A review.
- Author
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Cheng D, Jiang C, Xu J, Liu Z, and Mao X
- Subjects
- Alginates chemistry, Biomass, Glucuronic Acid metabolism, Hexuronic Acids, Hydrogen-Ion Concentration, Monosaccharides chemistry, Polysaccharide-Lyases chemistry, Protein Conformation, Protein Engineering, Substrate Specificity, Temperature, Oligosaccharides chemistry, Phaeophyceae enzymology, Polysaccharide-Lyases metabolism, Polysaccharides chemistry
- Abstract
Brown algae, as the main source of alginate, are a type of marine biomass with a very high output. Alginate, a polysaccharide composed of β-D-mannuronic acid (M) and α-L-guluronic acid (G), has great potential for applications in the food, cosmetic and pharmaceutical industries. Alginate lyases (Alys) can degrade alginate polymers into oligosaccharides or monosaccharides, resulting in a broad application field. Alys can be used for both the production of alginate oligosaccharides and the biorefinery of brown algae. In view of their important functions, an increasing number of Alys have been isolated and characterized. For better application, a comprehensive understanding of Alys is essential. Therefore, in this paper, we summarized recently discovered Alys, discussed their characteristics, and introduced their structural properties, degradation patterns and biological roles in alginate-degrading organisms. In addition, applications of Alys have been illustrated with examples. This paper provides a relatively comprehensive description of Alys, which is significant for Alys exploration and application., Competing Interests: Declaration of competing interest The authors declare that they have no competing interests., (Copyright © 2020 Elsevier B.V. All rights reserved.)
- Published
- 2020
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