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Abstract: A copper/iron‐cocatalyzed fluoroalkylative cyclization of 1,6‐enynes with readily available iodoperfluoroalkanes reagents for the synthesis of the corresponding fluoroalkylated pyrrolidines and benzofuran derivatives is reported. This novel protocol provides a mild method for the construction of Csp3‐CF2 and exocyclic double bonds in one step with high regio‐ and stereo‐selectivities. [ABSTRACT FROM AUTHOR]

A simple, efficient and practical iron-catalyzed azidoarylthiation of alkenes has been developed at room temperature, and the corresponding products containing ortho-sited sulfide and azide units were obtained in moderate to good yields with good tolerance of functional groups. The protocol uses readily available 1-(alkylthio)pyrrolidine-2,5-diones and trimethylsilyl azide as the alkylthiation and azidation reagents, respectively, inexpensive and environmentally friendly iron chloride as the catalyst without addition of any ligand and additive. [ABSTRACT FROM AUTHOR]

A simple and efficient catalyst-free method for isothiocyanatoalkylthiation of styrenes has been developed. The protocol uses (alkylthio)pyrrolidine-2,5-diones and trimethylsilyl isothiocyanate as the isothiocyanatoalkylthiolating reagents, dimethylformamide (DMF) as the solvent, and the reactions were completed within one hour with tolerance of some functional groups. No catalyst and additive were required in the reaction system, which avoided any contamination of transition metal catalysts in the target products. Therefore, the present method provides a convenient, efficient and practical strategy for the synthesis of compounds by a combination of sulfides and isothiocyanates. [ABSTRACT FROM AUTHOR]

A wide range of β-alkoxy sulfides are conveniently and efficiently obtained from alkenes using readily available 1-(arylthio)pyrrolidine-2,5-diones and alcohols as the oxysulfenylation reagents. [ABSTRACT FROM AUTHOR]