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Start Over Descriptor "neuron transformation" Topic rc321-571
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1. Cdk5 activation promotes Cos-7 cells transition towards neuronal-like cells

Author

Bao Li, Lan Xiao-Mei, Zhang Guo-Qing, Bao Xi, Li Bo, Ma Dan-Na, Luo Hong-Yan, Cao Shi-Lu, Liu Shun-Yao, Jing E, Zhang Jian-Zhong, and Zheng Ya-Li

Subjects
p35, cdk5 kinase activity, neuron transformation, ngf, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Cyclin-dependent kinase 5 (Cdk5) activity is specifically active in neurogenesis, and Cdk5 and neocortical neurons migration related biomarker are expressed in Cos-7 cells. However, the function of Cdk5 on the transformation of immortalized Cos-7 cells into neuronal-like cells is not clear.

Published
2023
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