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Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction caused mostly by drugs. Three of 22 AGEP cases (13.6%), recruited by us as part of two prospective multinational studies, occurred 24 to 48 hours after a spider bite. We suggest that a spider bite is a possible trigger for AGEP. [Copyright &y& Elsevier]

The article presents a case study of a 91 year old man with a rapidly growing tumour on his face, which had developed within the past few months. It was inferred that the patient was known to suffer from ischaemic heart disease and hypertension treated with aspirin, cilazapril, and metoprolol. Moreover, histological examination inferred a dense infiltrate involving the entire dermis, without involvement of the epidermis.

Pilonidal sinuses usually occur in the sacrococcygeal area in young men, and occasionally can be found in other ectopic sites. We present a retrospective case review on unusual locations of pilonidal sinuses in the past 4 years. The lesion sites were as follows: one on the penis, two on the scalp, two on the abdomen, one on the neck, two in the groin and two in the axilla. Abdominal and penile lesions are uncommon, but the other locations reported are unusually rare. To our knowledge, the groin has not been reported previously as a site of a pilonidal sinus, although the histological appearance of hidradenitis suppurativa may well resemble it. When trying to clarify the pathogenesis of these occurrences, we found that recurrent hair removal was a common characteristic of the patients we contacted, and this may have been the initiating trauma. [ABSTRACT FROM AUTHOR]

SUMMARY: A 60-year-old woman presented with a 3-week history of a pruritic papulo-nodular eruption on the face and trunk after a bee sting. Histological examination showed a predominantly lymphocytic infiltrate with follicular centres and tingible body macrophages. Immunohistochemically, positive staining for both kappa and lambda light chains was noted. The eruption settled with oral antihistamine and topical corticosteroid. These findings support the diagnosis of follicular B-cell pseudolymphoma. [ABSTRACT FROM AUTHOR]

Presents information on a study which reported the case of acne in an adolescent with a history of asymptomatic facial skin lesions since childhood. Results of the skin and physical examination of the patient; Details on lipoid proteinosis or Urbach-Wiethe disease.

The article discusses a case of a 42-year-old man who had an eruption on his chest and shoulders that had been present since early adolescence. Histologic examination revealed a cyst in the mid-dermis lined by flattened squamous epithelium, with a marked granular layer. The cyst was filled with compact laminated keratinous material and vellus hairs. The findings were consistent with eruptive vellus hair cysts. Another type of lesions consisted of widened follicular openings with projection of several hair shafts on his back, nose, and cheeks, compatible with the clinical picture of trichostasis spinulosa.