1. Selective extraction and detection of β-agonists in swine urine for monitoring illegal use in livestock breeding.
- Author
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Yuan Y, Nie H, Yin J, Han Y, Lv Y, and Yan H
- Subjects
- Adsorption, Animals, Body Fluids chemistry, Breeding, Chromatography, High Pressure Liquid methods, Clenbuterol urine, Drug and Narcotic Control, Graphite chemistry, Hazard Analysis and Critical Control Points, Isoproterenol analogs & derivatives, Isoproterenol urine, Molecular Imprinting, Nanostructures chemistry, Solid Phase Extraction instrumentation, Swine, Adrenergic beta-Agonists urine, Solid Phase Extraction methods, Veterinary Drugs urine
- Abstract
The illegal use of β-agonists often endangers animal-derived food safety. In this study, a selective detection method for β-agonists in swine urine was established via the combination of polymeric ionic liquid-molecularly imprinted graphene oxide-miniaturized pipette tip solid-phase extraction and high-performance liquid chromatography. It is worth noting that this method relied mainly on the designed adsorbent, which presented a rich adsorption mechanism, fast mass transfer rate, and high selectivity, and was successfully utilized in the selective extraction of β-agonists from swine urine samples. The proposed method has low LOD (0.20-0.56 ng/mL), high recovery (94.9-107.9%), and high reusability (4 times, 91.9-108.8%), which indicates its high potential as a selective, sensitive, accurate, and nonfatal method for monitoring the illegal use of β-agonists in the livestock breeding stage., (Copyright © 2020 Elsevier Ltd. All rights reserved.)
- Published
- 2020
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