1. Differences in glycemic trends due to reconstruction methods after proximal gastrectomy from the perspective of continuous glucose-monitoring.
- Author
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Shoda K, Kubota T, Kawaguchi Y, Akaike H, Maruyama S, Higuchi Y, Nakayama T, Saito R, Takiguchi K, Furuya S, Shiraishi K, Amemiya H, Kawaida H, and Ichikawa D
- Subjects
- Humans, Prospective Studies, Male, Female, Aged, Middle Aged, Plastic Surgery Procedures methods, Blood Glucose Self-Monitoring methods, Monitoring, Physiologic methods, Anastomosis, Surgical methods, Glycemic Control methods, Age Factors, Gastrectomy methods, Stomach Neoplasms surgery, Hypoglycemia etiology, Hypoglycemia prevention & control, Blood Glucose metabolism, Blood Glucose analysis, Postoperative Complications etiology, Postoperative Complications prevention & control
- Abstract
Purpose: In recent years, clinicians have focused on the importance of preventing hypoglycemia. We evaluated the impact of different reconstruction procedures after proximal gastrectomy on glycemic variability in non-diabetic patients with gastric cancer., Methods: This prospective observational study was conducted between April 2020 and March 2023. Flash continuous glucose-monitoring, a novel method for assessing glycemic control, was used to evaluate the glycemic profiles after gastrectomy. A flash continuous glucose-monitoring sensor was placed subcutaneously at the time of discharge, and glucose trends were evaluated for 2 weeks., Results: The anastomotic methods for proximal gastrectomy were esophagogastrostomy in 10 patients and double-tract reconstruction in 10 patients. The time below this range (glucose levels < 70 mg/dL) was significantly higher in the double-tract reconstruction group than in the esophagogastrostomy group (p = 0.049). A higher nocturnal time below this range was significantly correlated with an older age and double-tract reconstruction (p = 0.025 and p = 0.025, respectively)., Conclusion: These findings provide new insights into reconstruction methods after proximal gastrectomy by assessing postoperative hypoglycemia in non-diabetic patients with gastric cancer., (© 2024. The Author(s) under exclusive licence to Springer Nature Singapore Pte Ltd.)
- Published
- 2024
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