1. Nanoparticles as Drug Delivery Systems for the Targeted Treatment of Atherosclerosis.
- Author
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Pang, Alexander Shao-Rong, Dinesh, Tarini, Pang, Natalie Yan-Lin, Dinesh, Vishalli, Pang, Kimberley Yun-Lin, Yong, Cai Ling, Lee, Shawn Jia Jun, Yip, George W., Bay, Boon Huat, and Srinivasan, Dinesh Kumar
- Subjects
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DRUG delivery systems , *ATHEROSCLEROSIS , *NANOPARTICLES , *ATHEROSCLEROTIC plaque , *TREATMENT effectiveness - Abstract
Atherosclerosis continues to be a leading cause of morbidity and mortality globally. The precise evaluation of the extent of an atherosclerotic plaque is essential for forecasting its likelihood of causing health concerns and tracking treatment outcomes. When compared to conventional methods used, nanoparticles offer clear benefits and excellent development opportunities for the detection and characterisation of susceptible atherosclerotic plaques. In this review, we analyse the recent advancements of nanoparticles as theranostics in the management of atherosclerosis, with an emphasis on applications in drug delivery. Furthermore, the main issues that must be resolved in order to advance clinical utility and future developments of NP research are discussed. It is anticipated that medical NPs will develop into complex and advanced next-generation nanobotics that can carry out a variety of functions in the bloodstream. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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