1. Insecticidal sesquiterpene pyridine alkaloids from Maytenus chiapensis.
- Author
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Núñez MJ, Guadaño A, Jiménez IA, Ravelo AG, González-Coloma A, and Bazzocchi IL
- Subjects
- Alkaloids chemistry, Alkaloids pharmacology, Animals, Aphids drug effects, Cells, Cultured, El Salvador, Feeding Behavior drug effects, Insecticides chemistry, Insecticides pharmacology, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Plant Leaves chemistry, Pyridines chemistry, Pyridines pharmacology, Sesquiterpenes chemistry, Sesquiterpenes pharmacology, Spodoptera drug effects, Alkaloids isolation & purification, Insecticides isolation & purification, Maytenus chemistry, Plants, Medicinal chemistry, Pyridines isolation & purification, Sesquiterpenes isolation & purification
- Abstract
The new sesquiterpene pyridine alkaloids chiapenines ES-I (1), ES-II (2), ES-III (3), and ES-IV (4), in addition to the known alkaloids wilfordine (5), alatamine (6), wilforidine (7), alatusinine (8), euonine (9), euonymine (10), ebenifoline E-I (11), forrestine (12), mayteine (13), and 4-hydroxy-7-epi-chuchuhuanine E-V (14), were isolated from the leaves of Maytenus chiapensis. Their structures were elucidated by 1D and 2D NMR spectroscopy, including homonuclear and heteronuclear correlation (COSY, ROESY, HSQC, and HMBC) experiments. Wilfordine, alatusinine, and euonine exhibited strong antifeedant activity against Spodoptera littoralis.
- Published
- 2004
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