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The article examines a study from the University of Michigan that explores how vision impairment affects cognitive testing in older adults in India. Topics discussed include the impact of vision impairment on dementia risk, the methodological approach of the study, and the implications for cognitive testing accuracy.

A study conducted at JN Medical College in Aligarh, India, has reported on two cases of subacute sclerosing panencephalitis (SSPE), a rare neurological disorder caused by persistent measles virus infection. The patients, both children, presented with symptoms such as cognitive decline, myoclonus, and vision problems. The diagnosis was confirmed through clinical features, electroencephalogram patterns, and the presence of high levels of anti-measles antibodies in the serum and cerebrospinal fluid. The study emphasizes the importance of universal measles vaccination coverage to prevent SSPE and reduce the incidence of measles-related deaths. [Extracted from the article]

A recent study conducted in Nagpur, India, explored the potential benefits of agmatine in treating Huntington's disease (HD), a progressive neurodegenerative condition characterized by motor incoordination, cognitive decline, and psychiatric complications. The study used a rat model of HD induced by a mitochondrial toxin called 3-nitropropionic acid (3-NP). The results showed that agmatine treatment improved motor incoordination, depression-like behavior, and cognitive impairment associated with HD. It also normalized levels of certain neurotransmitters and neurotrophic factors in the brain. These findings suggest that agmatine may have a role in the pathogenesis and treatment of HD. [Extracted from the article]

A recent study from the Department of Life Sciences in Bangalore, India, explores the use of nanoscience in the development of therapeutic treatments for Alzheimer's disease (AD). The researchers discuss the challenges posed by the blood-brain barrier (BBB) in delivering drugs to the brain for neurodegenerative diseases. The study focuses on the current state-of-the-art of nanoparticle-based therapeutics for crossing the BBB. This research provides valuable insights into the potential of nanotechnology in the treatment of AD. [Extracted from the article]

A recent study conducted by researchers at Johns Hopkins University examined the association between dual sensory loss (hearing and vision loss) and cognitive function in older adults in India. The study analyzed data from the Longitudinal Aging Study in India and found that poor hearing and/or vision loss were associated with lower cognitive performance across various domains. The strongest association was observed in individuals with dual sensory loss. The researchers suggest that rehabilitative interventions for hearing and vision could potentially reduce the risk of dementia in India. [Extracted from the article]

A report from the National Institute of Mental Health and Neurosciences (NIMHANS) discusses research findings on dementia in India. The report highlights the rapid increase in the older adult population in India, with an estimated 142 million individuals aged 60 and above in 2022. The prevalence of dementia in India is estimated to be 8.8 million in 2016, with over 90% of cases remaining undiagnosed and untreated. The report emphasizes the urgent need for specialized workforce training to promote early diagnosis, intervention, and prevention of dementia, particularly in rural areas. It suggests expanding existing national programs and implementing specialized training courses to strengthen dementia care resources in India. [Extracted from the article]

A study conducted at the University of Petroleum and Energy Studies in Dehradun, India, focused on analyzing subcortical structures in Alzheimer's disease using ensemble learning. The researchers aimed to improve the diagnosis and detection of Alzheimer's disease by examining the connections between neuroregions. The study found that the hippocampus, amygdala, and neuroregion were the most effective in detecting Alzheimer's disease, mild cognitive impairment, and cognitive normal. This research has been peer-reviewed and provides valuable insights into the early detection of Alzheimer's disease. [Extracted from the article]

A recent study conducted at the Giridhar Eye Institute in Kerala, India, focused on the Miller Fisher variant of Guillain-Barre Syndrome. The study presented a case report of a healthy young male who experienced sudden onset binocular diplopia and bilateral abduction limitation, which rapidly progressed to near total ophthalmoplegia. The patient was diagnosed with Miller-Fisher syndrome and treated with intravenous immunoglobulin, resulting in significant recovery of ocular motility. The researchers emphasized the importance of considering Miller-Fisher syndrome in cases of abducent nerve palsy with normal imaging and no systemic risk factors, as it may not be well-known among ophthalmologists. [Extracted from the article]

A researcher at the Sanjay Gandhi Postgraduate Institute of Medical Sciences in India has presented data on multiple system atrophy (MSA), a neurodegenerative disease. The study aimed to evaluate the clinical profile of Parkinsonian features in MSA and found that these features can resemble those of progressive supranuclear palsy (PSP) or Parkinson's disease (PD). The study also found that a subset of MSA patients had features resembling PSP, while others had features resembling PD. The research concluded that the initial presentation of MSA can be deceptive and should be followed up. [Extracted from the article]

A study conducted by researchers at Annamalai University in Tamil Nadu, India, focuses on the detection of epileptic seizures using a hybrid CNN model on EEG signals. Epilepsy is a neurological disorder characterized by abnormal brain activity, resulting in seizures and other symptoms. The researchers propose a model that uses deep learning techniques to extract features from EEG signals and classify them using a convolutional neural network and support vector machine. The experimental results showed a 94% accuracy in detecting seizures and removing noise from the EEG signals. This research provides valuable insights into the development of more effective methods for diagnosing and managing epilepsy. [Extracted from the article]

A report from researchers at Alagappa University in Tamil Nadu, India discusses the findings on Parkinson's Disease. The research highlights the influence of epigenetic factors and single nucleotide polymorphisms (SNPs) in certain genes on the development of neurological conditions associated with Parkinson's Disease. The study focuses on the nutrigenomics of Parkinson's Disease and explores how genes are regulated in terms of nutritive factors and the genetic basis of the disease. The researchers summarize the impact of nutritive supplements on Parkinson's Disease and emphasize the potential therapeutic effects of nutrigenomics on chronic diseases. The research has been peer-reviewed and provides valuable insights into the genetic and nutritional aspects of Parkinson's Disease. [Extracted from the article]

A recent study conducted in Tamil Nadu, India, has developed a novel strategy for the early detection of Alzheimer's disease using deep learning models. The researchers utilized sophisticated sampling methods and a hybrid architecture combining Residual Neural Network (ResNet) and Long Short-Term Memory (LSTM) units. The results showed that this model outperformed traditional machine learning approaches in terms of accuracy, sensitivity, and specificity. The study also aimed to shed light on the decision-making process of the model and contribute to a better understanding of Alzheimer's disease biomarkers. This research provides a promising foundation for accurate and reliable identification of Alzheimer's disease, potentially improving patient outcomes. [Extracted from the article]

A recent report from Maharishi Markandeshwar (Deemed to be University) in Haryana, India, highlights the potential benefits of a combined intervention for individuals with spinal cord injury (SCI). The study focused on a 40-year-old male with traumatic incomplete paraplegia and aimed to improve trunk control, balance, and gait through pelvic proprioceptive neuromuscular facilitation and core strengthening exercises. After four weeks of intervention, significant improvements were observed in trunk control, gait, and balance. This case report suggests the potential therapeutic value of this intervention and calls for further research in this area. [Extracted from the article]

A recent report from Karnataka, India highlights the increasing recognition of autoimmune disorders, particularly anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis, as a significant cause of encephalitis. The case study presented a 17-year-old girl who initially presented with psychiatric symptoms such as low mood and memory difficulties, but later experienced dramatic changes in mood, hallucinations, and neurological symptoms. The diagnosis of anti-NMDAR encephalitis was made through electroencephalography and serum antibody testing, and the patient showed improvement with plasmapheresis and rituximab treatment. The study emphasizes the importance of considering autoimmune encephalitis in the differential diagnosis of psychiatric symptoms, and highlights the need for a multidisciplinary approach for evaluation and treatment. [Extracted from the article]

A report from Lovely Professional University in Punjab, India discusses the relationship between aluminum toxicity and neurodegeneration in Alzheimer's Disease. The researchers explain that aluminum is widely present in the environment and can easily enter the body, leading to toxic effects. They also suggest that consuming antioxidants may be beneficial in combating the oxidative stress associated with aluminum toxicity. The study highlights the need for effective treatments for Alzheimer's Disease, as current drugs have not proven to be successful. [Extracted from the article]

A new report from researchers at the Bangur Institute of Neurosciences in West Bengal, India, compares the effectiveness of two surgical treatments for hydrocephalus, a disorder characterized by the abnormal enlargement of the ventricles in the brain due to excessive accumulation of cerebrospinal fluid. The standard treatment is ventriculoperitoneal shunt (VPS), but this study suggests that endoscopic third ventriculostomy (ETV) may be a safer alternative, particularly for non-communicating hydrocephalus. The study found that ETV had a lower reoperation and complication rate compared to VPS at 4th, 12th, and 24th weeks after treatment. Aqueductal stenosis was the most common cause of hydrocephalus in both groups. [Extracted from the article]

A recent study from Uttar Pradesh, India provides an update on the diagnosis and management of tic disorders (TDs). TDs are common neuropsychiatric disorders that primarily affect children and adolescents, with a higher prevalence in males. The study highlights the complex interaction between genetic, environmental, and immunological factors in the development of TDs. The most plausible pathophysiology of TDs is dysregulation in the cortico-striato-pallido-thalamo-cortical network. The diagnosis of TDs is based on clinical features and neurological examination, and treatment options include psychoeducation, supportive therapy, and medication. The study emphasizes the importance of dispelling myths and promoting acceptance to improve patient outcomes. [Extracted from the article]

A recent study conducted in Karnataka, India compared the outcomes of two surgical procedures, endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS), in children with hydrocephalus due to primary aqueductal stenosis. The study included 89 children and found that overall procedural survival was better after ETV than VPS. The research also noted that VPS caused more reduction in linear indices of ventricles compared to ETV, but this did not affect the success or complication rates of the procedure. The study provides new insights into the treatment options for pediatric hydrocephalus. [Extracted from the article]

A recent study conducted in Assam, India, examined the effectiveness of psychosocial treatment programs in improving the quality of life (QOL) for individuals with epilepsy. The study reviewed 68 articles and included 12 articles in a meta-analysis, with a total of 1712 participants. The findings showed that psychosocial treatment programs significantly improved QOL, self-management, drug adherence, and reduced stigma among individuals with epilepsy. However, there was limited evidence for reducing anxiety, depression, seizure frequency, and improving knowledge. The researchers recommend further research to target these specific outcomes and emphasize the importance of incorporating psychosocial treatment programs in epilepsy care to promote patients' well-being. [Extracted from the article]

A recent report discusses research findings on epilepsy, focusing on the interpretation of electroencephalogram (EEG) signals for diagnosis. The researchers from Sri Eshwar College of Engineering in Tamil Nadu, India, propose a hybrid technique called Sparse ELM-ABO fusion for epileptic seizure identification. This technique combines the Extreme Learning Machine (ELM) with the African Buffalo Optimization (ABO) algorithm to improve speed, accuracy, and reduce storage space. The proposed model achieved high accuracy in binary and multi-label classification, with scores of 96.08% and 90.89% respectively. [Extracted from the article]

A recent study conducted by researchers at Hemchandracharya North Gujarat University in India explores the concept of ferroptosis, an iron-dependent programmed cell death, and its association with neurodegenerative diseases such as Parkinson's and Alzheimer's disease, strokes, and brain tumors. The study highlights the role of major molecular key players and various mechanisms involved in the ferroptosis pathway, as well as the potential therapeutic effects of nanomaterials in preventing and treating these diseases. The research suggests that a combination of nanomaterials and ferroptosis could be a promising approach in the field of nanomedicine. [Extracted from the article]

A recent report from Nizam's Institute of Medical Sciences in Telangana, India, discusses a case of pediatric pleomorphic xanthoastrocytoma (PXA) with neoplastic meningitis. PXA is a rare tumor typically found in children and young adults, commonly in the temporal lobes. The report describes the case of a 17-year-old male with a grade 3 PXA tumor, presenting with seizures and signs of raised intracranial pressure. The researchers emphasize the importance of aggressive management for PXA grade 3 tumors with cerebrospinal fluid spread, including routine baseline and follow-up craniospinal screening. [Extracted from the article]

Researchers from Manipal Academy of Higher Education in Karnataka, India, have conducted a study on Parkinson's disease (PD) patients with urinary dysfunction. The study analyzed urinary extracellular vesicles (EVs) in 29 PD cases and compared them to age-matched controls. The researchers found no significant difference in urinary EV size, concentration, and protein concentration between PD cases with urinary dysfunction and controls. However, they did observe a positive association between urinary EV concentration and motor scores. The study suggests that chronic stress induced by motor symptoms may contribute to excessive EV production in PD patients with urinary dysfunctions. Further research is needed to explore the association between urinary EV dynamics and motor and non-motor symptoms in PD. [Extracted from the article]

A recent study conducted in Uttar Pradesh, India, explored the relationship between impulse-control disorders (ICD-RBs) and restless leg syndrome (RLS) in patients with Parkinson's disease (PD). The study found that 48.6% of PD patients displayed at least one ICD-RB, with compulsive medication use being the most common behavior. Additionally, 26.3% of patients had RLS, and 68.4% of these patients displayed at least one ICD-RB. The study suggests that the co-occurrence of RLS and ICD-RBs may be due to circadian fluctuations in dopamine release and long-term dopaminergic treatment or degenerative processes. [Extracted from the article]

A new report discusses research conducted by Swami Vivekananda Yoga Anusandhana Samsthana in India on the potential benefits of yoga for patients with Parkinson's disease (PD). The study aims to investigate whether sustained yoga intervention can slow the progression of PD. Over 18 months, 160 PD patients will be randomly assigned to either an interventional or control group. The primary outcome will be the difference in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score after 18 months of intervention. This study is the first controlled trial to examine the long-term effects of yoga as an adjuvant therapy for PD. [Extracted from the article]

Researchers at the Thapar Institute of Engineering & Technology in Punjab, India have developed a deep learning method using multi-layer perceptron (MLP) and long short-term memory (LSTM) to identify genes associated with Parkinson's disease. The method utilizes amino acid's physicochemical properties to construct a feature vector and employs feature extraction techniques to reduce noise and improve efficiency. The experimental results show that the proposed approach outperforms existing methods with higher recall, precision, and F-score. This research provides an efficient and accurate method for identifying and classifying genes related to Parkinson's disease. [Extracted from the article]

A recent study conducted in Mumbai, India, focused on giant prolactinomas (GP), a rare type of tumor that accounts for 4.3% of prolactinomas. The study aimed to describe the clinical, biochemical, radiological, and treatment outcomes of Asian-Indian patients with GP. The research found that GP predominantly affects males and that dopamine-agonist therapy was effective in achieving normal prolactin levels and reducing tumor size. However, gonadal axis recovery was poor in patients treated with dopamine-agonists alone. The study concluded that dopamine-agonist therapy as a first-line treatment for GP resulted in better preservation of hormone axes. [Extracted from the article]

A recent study conducted by researchers at Manipal Academy of Higher Education in India has found a link between dysbiosis of gut bacteria and Parkinson's disease (PD). The researchers analyzed fecal samples from PD patients and healthy controls and found that certain bacterial families were more abundant in PD cases, while others were lower in abundance. The study also found a positive correlation between certain bacterial genera and constipation in PD patients. These findings contribute to the growing body of research on the gut microbiome in PD and provide new insights into the gut microbial composition of PD patients in the south Indian population. [Extracted from the article]

A recent study conducted at the National Institute of Mental Health and Neurosciences (NIMHANS) in India explored the phenotypic features of epilepsy caused by sodium channelopathies. The study found that sodium channel mutations were clinically significant in 23 out of 112 children with epilepsy who underwent genetic testing. The children exhibited various clinical presentations, including different types of seizures and other phenotypic features such as movement disorders. The researchers concluded that early clinical diagnosis could help tailor treatment for patients with sodium channelopathies. [Extracted from the article]

A recent study conducted in Uttar Pradesh, India, focused on the incidence and radiological distribution of post-traumatic early cerebral infarction (PTCI). The researchers found that PTCI is common in head injuries and can lead to neurological deterioration. They also discovered that Magnetic Resonance Imaging (MRI) is more sensitive than Computed Tomography (CT) scans in detecting early infarctions, especially the lacunar types. The study highlights the importance of using MRI to accurately diagnose and monitor PTCI in patients with head injuries. [Extracted from the article]

A recent study conducted by researchers at Santhiram College of Pharmacy in Andhra Pradesh, India, has explored the potential of using quercetin nanocrystals (QNC) to treat Parkinson's disease. Quercetin, a compound with pharmacological effects on neurodegenerative diseases, has limited use in pharmaceutical applications due to its low solubility in water and poor bioavailability. The study utilized a network-pharmacology-based methodology to identify the targets of quercetin relevant to Parkinson's disease treatment and investigate the associated pharmacological mechanisms. The results showed that QNC effectively reduced the adverse effects caused by rotenone-induced oxidative stress, suggesting its potential as a treatment for Parkinson's disease. Further clinical trials are needed to assess its effectiveness. [Extracted from the article]

Keywords: Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Dementia; Health and Medicine; India; Mental Health; Neurodegenerative Diseases and Conditions EN Brain Diseases and Conditions Central Nervous System Diseases and Conditions Dementia Health and Medicine India Mental Health Neurodegenerative Diseases and Conditions 534 534 1 06/19/23 20230623 NES 230623 2023 JUN 19 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Researchers detail new data in dementia. Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Dementia, Health and Medicine, India, Mental Health, Neurodegenerative Diseases and Conditions. [Extracted from the article]

Keywords for this news article include: Sri Ramachandra Institute of Higher Education and Research, Antibodies, Hospitals, Immunology, Autoimmunity, Encephalitis, Blood Proteins, Immunoglobulins, Health and Medicine, Brain Diseases and Conditions, Virus Diseases and Conditions, Central Nervous System Infections, Central Nervous System Diseases and Conditions, Central Nervous System Viral Diseases and Conditions. Antibodies, Autoimmunity, Blood Proteins, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Central Nervous System Infections, Central Nervous System Viral Diseases and Conditions, Encephalitis, Health and Medicine, Hospitals, Immunoglobulins, Immunology, Proteins, Virus Diseases and Conditions Keywords: Antibodies; Autoimmunity; Blood Proteins; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Central Nervous System Infections; Central Nervous System Viral Diseases and Conditions; Encephalitis; Health and Medicine; Hospitals; Immunoglobulins; Immunology; Proteins; Virus Diseases and Conditions EN Antibodies Autoimmunity Blood Proteins Brain Diseases and Conditions Central Nervous System Diseases and Conditions Central Nervous System Infections Central Nervous System Viral Diseases and Conditions Encephalitis Health and Medicine Hospitals Immunoglobulins Immunology Proteins Virus Diseases and Conditions 2023 MAR 6 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- A new study on encephalitis is now available. [Extracted from the article]

Keywords: Mysuru; India; Asia; Alzheimer Disease; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Dementia; Emerging Technologies; Health and Medicine; Nanoparticles; Nanotechnology; Neurodegenerative Diseases and Conditions; Risk and Prevention; Tauopathies EN Mysuru India Asia Alzheimer Disease Brain Diseases and Conditions Central Nervous System Diseases and Conditions Dementia Emerging Technologies Health and Medicine Nanoparticles Nanotechnology Neurodegenerative Diseases and Conditions Risk and Prevention Tauopathies 2023 MAR 6 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Research findings on Neurodegenerative Diseases and Conditions - Alzheimer Disease are discussed in a new report. Mysuru, India, Asia, Alzheimer Disease, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Dementia, Emerging Technologies, Health and Medicine, Nanoparticles, Nanotechnology, Neurodegenerative Diseases and Conditions, Risk and Prevention, Tauopathies. [Extracted from the article]