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Objectives: To ascertain the degree of precision and repeatability inherent in the "capture to edit" digital imaging system, namely the ColorChecker Passport Photo (X-Rite, MI, USA), and to juxtapose its performance against spectrophotometric assessments utilizing the Vita Easyshade® (Vita Zahnfabrik, H Rauter GmbH & Co. KG., Bad Sackingen, Germany) for the same set of teeth., Materials and Methods: Eighty participants aged 19-25 were included in the study; all of them were Croatian students at the School of Dental Medicine, University of Zagreb. Color measurements of the maxillary right central incisors were performed in controlled, standardized laboratory conditions. The measurements were performed on calibrated digital photographs by an experienced clinician three times in a row, and L, a, and b of CIELAB color space values were recorded. The same procedure was performed using the Vita Easyshade 5.0 spectrophotometer (Vita Zahnfabrik, Bad Säckingen, Germany) in "Tooth single" mode., Results: The Cronbach's alpha was used as a repeatability measurement, thus revealing high consistency for both methods (α=0.94-1). Correlations were moderate (Pearson r=0.44-0.66 p<0.05). Testing confirmed that digital photography is inaccurate as spectrophotometry (p<0.05). An analysis of errors of means and their standard deviations revealed consistent discrepancies with minor deviations., Conclusion: The "capture to edit" method showed high consistency (Cronbach's α=0.94-0.96), and it exhibits comparability in terms of variability, reliability, and repeatability when compared to spectrophotometric measurement (VitaShade 5, VitaZahnfabrik). Disparities between the methods are evident and anticipated, yet they do not follow a consistently linear pattern. The combination of repeatability and consistency renders the "capture to edit" method a valuable tool for enhanced color mapping, thus facilitating comparisons between digital images., Competing Interests: Conflict of interest: None declared., (University of Zagreb School of Dental Medicine.)

Background: Croatia and Slovenia were the transit countries on the Balkan route for migrants and refugees from Middle East countries in 2015 and 2016. They had to optimize health care delivery in the special circumstances in refugee camps and transit centres. Little is known about health care provision in border camps where a large number of migrants stay for only couple of hours. Previous studies emphasize that language barriers and cultural differences play a central part in the relationship between health workers and migrants inside the transit zone. The aim of the study was to identify specific characteristics of health care provision experienced by primary healthcare providers in order to prepare solutions on how to organise health care in refugee settings., Methods: Twelve thematic interviews were conducted in the middle of the most intense migration movements to the North-West Europe between November and December 2015 with health workers from Croatia and Slovenia. Interview transcripts were read, coded, reviewed, and labelled. We used qualitative content analysis., Results: Four themes about the health service provision for refugees at Schengen border were identified. The circumstance when mutual understanding is poor and the consultation not successful, cultural differences represent a central barrier. Participants highlighted that the importance of respecting human dignity is crucial for the provision of basic medical care for migrants in transit., Conclusion: Successful overcoming language barriers, respecting cultural differences, humanity, susceptibility to social deprivation and traumatic experiences are the key factors important for organisation of health care in transit centers and camps. This article gives some useful tips for healthcare workers and policy makers who are participating in health services provision for migrants and other refugees. Health workers should be prepared to work in special working conditions with a lack of resources. Their work would require timely planning and reflection on the organization of more transit camps., Trial Registration: Ethical Committee of the Republic of Slovenia approved the study as a project number 112/02/16.

Objective: The purpose of this randomized clinical trial was to assess the efficacy of color change in combined in-office/at-home whitening., Materials and Methods: Thirty participants were randomly divided into two groups: 15 received combined treatment in-office whitening (6% hydrogen peroxide + 2 weeks at-home whitening with 16% carbamide peroxide [CP]); 15 were assigned to control group. Instrumental color measurements were obtained before whitening (t 0 ), immediately after in-office whitening (t in-office ), after 1 week of active treatments (t 1 ), and at the completion of the whitening treatment (t 2 ). CIE L*a*b* values were recorded and CIE L*a*b* and CIEDE2000 color differences were calculated., Results: The color change at t in-office was ΔE ab = 4.7 and ΔE 00 = 3.2 and overall color change of combined method at t 2 was ΔE ab = 8.2 and ΔE 00 = 5.3 (P < 0.05). A statistically significant effect for the mean CIE L*a*b* and CIEDE2000 values was detected within time with the mean a*, b* and C' values decreasing and mean h' values increasing significantly (P < 0.05)., Conclusions: Combined in-office/at-home whitening was effective. Whitening efficacy increased upon application of 16% CP in combined in-office/at-home treatment (P < 0.05)., Clinical Significance: The statistically significant increase in color change recommends clinical application of combined in-office/at-home whitening treatment., (© 2019 Wiley Periodicals, Inc.)

Extended-spectrum beta-lactamases are responsible for resistance of Gram-negative bacilli to several beta-lactam antibiotics, including those prescribed for treatment pneumonia. To evaluate the importance of colonization with E-GNB for the choice of empirical treatment we performed a retrospective case-control study including 156 patients, hospitalized for treatment of pneumonia from 2009 through 2013. Empirical treatment success and in-hospital survival were significantly lower in patients colonized with E-GNB compared to non-colonized (p = 0.002, p = 0.035). When comparing subgroups of colonized patients, treatment success was significantly lower in patients who were colonized with E-GNB resistant to empirical antibiotic (p = 0.010), but not in those colonized by E-GNB susceptible to empirically given antibiotic (p = 0.104). Difference in in-hospital mortality was insignificant in both subgroups (p = 0.056, p = 0.331). The results of study suggest that an anti-E-GNB active antibiotic should be used for empirical treatment of pneumonia in E-GNB colonized patients.

Complex regional pain syndrome (CRPS) represents a state of constant and often disabling pain, affecting one region (usually hand) and often occurs after a trauma whose severity does not correlate with the level of pain. The older term for this condition of chronic pain associated with motor and autonomic symptoms is reflex sympathetic dystrophy or causalgia. The aim of this review, based on contemporary literature, is to show the epidemiology and etiology, proposed pathophysiological mechanisms, method of diagnosis and treatment options, prevention and mitigation of this under-recognized disease. CRPS I occurs without known neurological damage, unlike CRPS II, where the history of trauma is present and in some cases damage to the peripheral nervous system can be objectively assessed using electromyoneurography. New diagnostic methods, such as quantitative sensory testing (CST), challenge this division because the CST findings in patients with CRPS I can suggest damage to Adelta peripheral nerve fibers. Except for distinguishing type I and type II disease, it is important to bear in mind the diversity of clinical presentation of CRPS in acute and chronic phase of the disease. This regional pain syndrome typically includes the autonomic and motor signs and thus differs from other peripheral neuropathic pain syndromes. The complexity of the clinical presentation indicates the likely presence of different pathophysiological mechanisms underlying this disease. Previous studies have demonstrated the autonomic dysfunction, neurogenic inflammation and neuroplastic changes. The diagnosis of CRPS is based on anamnesis and clinical examination on the basis of which the disease can be graded according to the Budapest Criteria. A valuable aid in differentiating subtypes of the disease is electromyoneurography. The treatment of CRPS is as complex as the clinical picture and the pathophysiology of the disease and requires interdisciplinary cooperation and individual approach. The pharmacological approach is mainly symptomatic, including analgesics, glucocorticoids, baclofen, bisphosphonates and prophylactic administration of vitamin C. Physical therapy besides preventing atrophy and contractures reduces the use of analgesic therapy. Invasive approach includes stimulation of the spinal cord, peripheral nerve catheters with anesthetic and amputation that patients in severe condition gladly accept. Further research is needed to better understand the disease and more effective therapies.

Objective: The aim of this study was to assess the level of patients' satisfaction with appearance of maxillary anterior teeth restorations and to determine if there is a significant difference in patients' assessment of restoration appearance with regard to gender., Materials and Methods: Two hundred subjects evaluated the colour, anatomical shape and surface texture of maxillary anterior teeth restorations (composite fillings, acrylic faceted metal crowns, porcelain-fused-to-metal crowns and all-ceramic crowns) in comparison with adjacent natural teeth. The data were expressed in patients' average assessment scores for colour, anatomical shape and surface texture as well as overall patients' average assessment scores for every type of restoration and overall patients' average assessment scores for colour, anatomical shape and surface texture of all the restorations in general. Patients also assessed the general impression of their maxillary anterior teeth restorations and rated it as satisfactory or unsatisfactory., Results: There was a statistically significant gender difference in patient assessment of colour and surface texture for composite fillings and the overall patient average assessment score for colour of all assessments (p <0.05). Women were more dissatisfied with the general impression of their restorations on the upper teeth than men (p >0.05). Only overall patients' average assessment score for composite restorations almost reached the level of significance (p = 0.069) on patients' general impression., Conclusion: Colour of the restorations and the composite material are significant factors which affect dental appearance of maxillary anterior teeth in patients.